Gene Gene information from NCBI Gene database.
Entrez ID 79364
Gene name ZXD family zinc finger C
Gene symbol ZXDC
Synonyms (NCBI Gene)
ZXDL
Chromosome 3
Chromosome location 3q21.3
miRNA miRNA information provided by mirtarbase database.
1415
miRTarBase ID miRNA Experiments Reference
MIRT026669 hsa-miR-192-5p Microarray 19074876
MIRT047258 hsa-miR-181b-5p CLASH 23622248
MIRT439173 hsa-miR-218-5p HITS-CLIP 23212916
MIRT439173 hsa-miR-218-5p HITS-CLIP 23212916
MIRT1544423 hsa-miR-103a CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14
GO ID Ontology Definition Evidence Reference
GO:0003712 Function Transcription coregulator activity IBA
GO:0003713 Function Transcription coactivator activity IEA
GO:0003713 Function Transcription coactivator activity IMP 17493635
GO:0005515 Function Protein binding IPI 16600381, 17493635, 17696781, 23275563, 27705803, 29892012, 32296183, 32814053, 33961781
GO:0005634 Component Nucleus IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
615746 28160 ENSG00000070476
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q2QGD7
Protein name Zinc finger protein ZXDC (ZXD-like zinc finger protein)
Protein function Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00096 zf-C2H2 208 232 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 238 262 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 388 412 Zinc finger, C2H2 type Domain
Tissue specificity TISSUE SPECIFICITY: Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen. {ECO:0000269|PubMed:16600381}.
Sequence
MDLPALLPAPTARGGQHGGGPGPLRRAPAPLGASPARRRLLLVRGPEDGGPGARPGEASG
PSPPPAEDDSDGDSFLVLLEVPHGGAAAEAAGSQEAEPGSRVNLASRPEQGPSGPAAPPG
PGVAPAGAVTISSQDLLVRLDRGVLALSAPPGPATAGAAAPRRAPQASGPSTPGYRCPEP
QCALAFAKKHQLKVHLLTHGGGQGRRPFKCPLEGCGWAFTTSYKLKRHLQSHDKLRPFGC
PVGGCGKKFTTVYNLKAHMKGH
EQESLFKCEVCAERFPTHAKLSSHQRSHFEPERPYKCD
FPGCEKTFITVSALFSHNRAHFREQELFSCSFPGCSKQYDKACRLKIHLRSHTGERPFIC
DSDSCGWTFTSMSKLLRHRRKHDDDRRFTCPVEGCGKSFTRAEHLKGHSITHLGTKPFEC
PVEGCCARFSARSSLYIHSKKHVQDVGAPKSRCPVSTCNRLFTSKHSMKAHMVRQHSRRQ
DLLPQLEAPSSLTPSSELSSPGQSELTNMDLAALFSDTPANASGSAGGSDEALNSGILTI
DVTSVSSSLGGNLPANNSSLGPMEPLVLVAHSDIPPSLDSPLVLGTAATVLQQGSFSVDD
VQTVSAGALGCLVALPMKNLSDDPLALTSNSNLAAHITTPTSSSTPRENASVPELLAPIK
VEPDSPSRPGAVGQQEGSHGLPQSTLPSPAEQHGAQDTELSAGTGNFYLESGGSARTDYR
AIQLAKEKKQRGAGSNAGASQSTQRKIKEGKMSPPHFHASQNSWLCGSLVVPSGGRPGPA
PAAGVQCGAQGVQVQLVQDDPSGEGVLPSARGPATFLPFLTVDLPVYVLQEVLPSSGGPA
GPEATQFPGSTINLQDLQ
Sequence length 858
Interactions View interactions
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
COLOR VISION DISORDER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Glomerulonephritis IGA Associate 38154557
★☆☆☆☆
Found in Text Mining only
Inflammation Associate 23954399
★☆☆☆☆
Found in Text Mining only
Moyamoya Disease Associate 26530418
★☆☆☆☆
Found in Text Mining only
Polycythemia Vera Associate 28427458
★☆☆☆☆
Found in Text Mining only