Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	79175
Gene name	Zinc finger protein 343
Gene symbol	ZNF343
Synonyms (NCBI Gene)	dJ734P14.5
Chromosome	20
Chromosome location	20p13

183

Show/Hide all (183)

miRTarBase ID	miRNA	Experiments	Reference
MIRT714759	hsa-miR-595	HITS-CLIP	19536157
MIRT714758	hsa-miR-4789-3p	HITS-CLIP	19536157
MIRT714757	hsa-miR-4643	HITS-CLIP	19536157
MIRT714756	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT714755	hsa-miR-942-5p	HITS-CLIP	19536157
MIRT714754	hsa-miR-466	HITS-CLIP	19536157
MIRT714753	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT714752	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT714751	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT714759	hsa-miR-595	HITS-CLIP	19536157
MIRT714758	hsa-miR-4789-3p	HITS-CLIP	19536157
MIRT714757	hsa-miR-4643	HITS-CLIP	19536157
MIRT714756	hsa-miR-6845-3p	HITS-CLIP	19536157
MIRT714755	hsa-miR-942-5p	HITS-CLIP	19536157
MIRT714754	hsa-miR-466	HITS-CLIP	19536157
MIRT714753	hsa-miR-6873-3p	HITS-CLIP	19536157
MIRT714752	hsa-miR-4768-5p	HITS-CLIP	19536157
MIRT714751	hsa-miR-6833-3p	HITS-CLIP	19536157
MIRT1522865	hsa-let-7a	CLIP-seq
MIRT1522866	hsa-let-7b	CLIP-seq
MIRT1522867	hsa-let-7c	CLIP-seq
MIRT1522868	hsa-let-7d	CLIP-seq
MIRT1522869	hsa-let-7e	CLIP-seq
MIRT1522870	hsa-let-7f	CLIP-seq
MIRT1522871	hsa-let-7g	CLIP-seq
MIRT1522872	hsa-let-7i	CLIP-seq
MIRT1522873	hsa-miR-1	CLIP-seq
MIRT1522874	hsa-miR-1202	CLIP-seq
MIRT1522875	hsa-miR-1294	CLIP-seq
MIRT1522876	hsa-miR-15a	CLIP-seq
MIRT1522877	hsa-miR-15b	CLIP-seq
MIRT1522878	hsa-miR-16	CLIP-seq
MIRT1522879	hsa-miR-195	CLIP-seq
MIRT1522880	hsa-miR-196a	CLIP-seq
MIRT1522881	hsa-miR-196b	CLIP-seq
MIRT1522882	hsa-miR-202	CLIP-seq
MIRT1522883	hsa-miR-206	CLIP-seq
MIRT1522884	hsa-miR-2355-5p	CLIP-seq
MIRT1522885	hsa-miR-3164	CLIP-seq
MIRT1522886	hsa-miR-3194-5p	CLIP-seq
MIRT1522887	hsa-miR-3673	CLIP-seq
MIRT1522888	hsa-miR-3972	CLIP-seq
MIRT1522889	hsa-miR-424	CLIP-seq
MIRT1522890	hsa-miR-4257	CLIP-seq
MIRT1522891	hsa-miR-4458	CLIP-seq
MIRT1522892	hsa-miR-4500	CLIP-seq
MIRT1522893	hsa-miR-4530	CLIP-seq
MIRT1522894	hsa-miR-4727-5p	CLIP-seq
MIRT1522895	hsa-miR-4765	CLIP-seq
MIRT1522896	hsa-miR-4769-3p	CLIP-seq
MIRT1522897	hsa-miR-497	CLIP-seq
MIRT1522898	hsa-miR-605	CLIP-seq
MIRT1522899	hsa-miR-613	CLIP-seq
MIRT1522900	hsa-miR-98	CLIP-seq
MIRT1522896	hsa-miR-4769-3p	CLIP-seq
MIRT2157958	hsa-miR-4797-5p	CLIP-seq
MIRT1522865	hsa-let-7a	CLIP-seq
MIRT1522866	hsa-let-7b	CLIP-seq
MIRT1522867	hsa-let-7c	CLIP-seq
MIRT1522868	hsa-let-7d	CLIP-seq
MIRT1522869	hsa-let-7e	CLIP-seq
MIRT1522870	hsa-let-7f	CLIP-seq
MIRT1522871	hsa-let-7g	CLIP-seq
MIRT1522872	hsa-let-7i	CLIP-seq
MIRT2377442	hsa-miR-1182	CLIP-seq
MIRT2377443	hsa-miR-1224-5p	CLIP-seq
MIRT1522875	hsa-miR-1294	CLIP-seq
MIRT2377444	hsa-miR-1299	CLIP-seq
MIRT1522880	hsa-miR-196a	CLIP-seq
MIRT1522881	hsa-miR-196b	CLIP-seq
MIRT1522882	hsa-miR-202	CLIP-seq
MIRT2377445	hsa-miR-223	CLIP-seq
MIRT2377446	hsa-miR-224	CLIP-seq
MIRT1522885	hsa-miR-3164	CLIP-seq
MIRT2377447	hsa-miR-3170	CLIP-seq
MIRT2377448	hsa-miR-3177-5p	CLIP-seq
MIRT2377449	hsa-miR-326	CLIP-seq
MIRT2377450	hsa-miR-330-5p	CLIP-seq
MIRT2377451	hsa-miR-3657	CLIP-seq
MIRT2377452	hsa-miR-3909	CLIP-seq
MIRT1522890	hsa-miR-4257	CLIP-seq
MIRT1522891	hsa-miR-4458	CLIP-seq
MIRT1522892	hsa-miR-4500	CLIP-seq
MIRT2377453	hsa-miR-451b	CLIP-seq
MIRT2377454	hsa-miR-4669	CLIP-seq
MIRT2377455	hsa-miR-4672	CLIP-seq
MIRT2377456	hsa-miR-4696	CLIP-seq
MIRT2377457	hsa-miR-4713-5p	CLIP-seq
MIRT1522895	hsa-miR-4765	CLIP-seq
MIRT2377458	hsa-miR-642b	CLIP-seq
MIRT2377459	hsa-miR-875-3p	CLIP-seq
MIRT2377460	hsa-miR-934	CLIP-seq
MIRT2377461	hsa-miR-942	CLIP-seq
MIRT1522900	hsa-miR-98	CLIP-seq
MIRT1522890	hsa-miR-4257	CLIP-seq
MIRT2377442	hsa-miR-1182	CLIP-seq
MIRT2669864	hsa-miR-1185	CLIP-seq
MIRT2377443	hsa-miR-1224-5p	CLIP-seq
MIRT2669865	hsa-miR-125a-5p	CLIP-seq
MIRT2669866	hsa-miR-125b	CLIP-seq
MIRT2669867	hsa-miR-127-5p	CLIP-seq
MIRT2377444	hsa-miR-1299	CLIP-seq
MIRT2669868	hsa-miR-2467-5p	CLIP-seq
MIRT2669869	hsa-miR-3136-5p	CLIP-seq
MIRT2669870	hsa-miR-3150a-3p	CLIP-seq
MIRT2669871	hsa-miR-3173-5p	CLIP-seq
MIRT2669872	hsa-miR-3175	CLIP-seq
MIRT2377448	hsa-miR-3177-5p	CLIP-seq
MIRT2669873	hsa-miR-3188	CLIP-seq
MIRT2377449	hsa-miR-326	CLIP-seq
MIRT2377450	hsa-miR-330-5p	CLIP-seq
MIRT2669874	hsa-miR-3605-5p	CLIP-seq
MIRT2669875	hsa-miR-3616-3p	CLIP-seq
MIRT2669876	hsa-miR-3647-3p	CLIP-seq
MIRT2377451	hsa-miR-3657	CLIP-seq
MIRT2669877	hsa-miR-3659	CLIP-seq
MIRT2669878	hsa-miR-3679-5p	CLIP-seq
MIRT2377452	hsa-miR-3909	CLIP-seq
MIRT2669879	hsa-miR-3913-3p	CLIP-seq
MIRT2669880	hsa-miR-3915	CLIP-seq
MIRT2669881	hsa-miR-3975	CLIP-seq
MIRT1522890	hsa-miR-4257	CLIP-seq
MIRT2669882	hsa-miR-4287	CLIP-seq
MIRT2669883	hsa-miR-4319	CLIP-seq
MIRT2669884	hsa-miR-4420	CLIP-seq
MIRT2669885	hsa-miR-4436b-3p	CLIP-seq
MIRT2669886	hsa-miR-4439	CLIP-seq
MIRT2669887	hsa-miR-4469	CLIP-seq
MIRT2669888	hsa-miR-4658	CLIP-seq
MIRT2669889	hsa-miR-4667-5p	CLIP-seq
MIRT2377454	hsa-miR-4669	CLIP-seq
MIRT2377455	hsa-miR-4672	CLIP-seq
MIRT2669890	hsa-miR-4685-3p	CLIP-seq
MIRT2669891	hsa-miR-4689	CLIP-seq
MIRT2669892	hsa-miR-4700-5p	CLIP-seq
MIRT2669893	hsa-miR-4711-3p	CLIP-seq
MIRT2377457	hsa-miR-4713-5p	CLIP-seq
MIRT2669894	hsa-miR-4721	CLIP-seq
MIRT2669895	hsa-miR-4732-3p	CLIP-seq
MIRT2669896	hsa-miR-485-5p	CLIP-seq
MIRT2669897	hsa-miR-489	CLIP-seq
MIRT2669898	hsa-miR-510	CLIP-seq
MIRT2669899	hsa-miR-574-5p	CLIP-seq
MIRT2669900	hsa-miR-593	CLIP-seq
MIRT2669901	hsa-miR-637	CLIP-seq
MIRT2377458	hsa-miR-642b	CLIP-seq
MIRT2669902	hsa-miR-668	CLIP-seq
MIRT2669903	hsa-miR-670	CLIP-seq
MIRT2377459	hsa-miR-875-3p	CLIP-seq
MIRT2377460	hsa-miR-934	CLIP-seq
MIRT2669904	hsa-miR-939	CLIP-seq
MIRT2377461	hsa-miR-942	CLIP-seq
MIRT2669905	hsa-miR-943	CLIP-seq
MIRT2377442	hsa-miR-1182	CLIP-seq
MIRT2669864	hsa-miR-1185	CLIP-seq
MIRT2377443	hsa-miR-1224-5p	CLIP-seq
MIRT2669867	hsa-miR-127-5p	CLIP-seq
MIRT2377444	hsa-miR-1299	CLIP-seq
MIRT2669870	hsa-miR-3150a-3p	CLIP-seq
MIRT2669871	hsa-miR-3173-5p	CLIP-seq
MIRT2669872	hsa-miR-3175	CLIP-seq
MIRT2377448	hsa-miR-3177-5p	CLIP-seq
MIRT2377449	hsa-miR-326	CLIP-seq
MIRT2377450	hsa-miR-330-5p	CLIP-seq
MIRT2669874	hsa-miR-3605-5p	CLIP-seq
MIRT2669876	hsa-miR-3647-3p	CLIP-seq
MIRT2669878	hsa-miR-3679-5p	CLIP-seq
MIRT2669879	hsa-miR-3913-3p	CLIP-seq
MIRT2669880	hsa-miR-3915	CLIP-seq
MIRT1522890	hsa-miR-4257	CLIP-seq
MIRT2669884	hsa-miR-4420	CLIP-seq
MIRT2669889	hsa-miR-4667-5p	CLIP-seq
MIRT2377455	hsa-miR-4672	CLIP-seq
MIRT2669891	hsa-miR-4689	CLIP-seq
MIRT2669892	hsa-miR-4700-5p	CLIP-seq
MIRT2669893	hsa-miR-4711-3p	CLIP-seq
MIRT2669897	hsa-miR-489	CLIP-seq
MIRT2669900	hsa-miR-593	CLIP-seq
MIRT2669901	hsa-miR-637	CLIP-seq
MIRT2377458	hsa-miR-642b	CLIP-seq
MIRT2377459	hsa-miR-875-3p	CLIP-seq
MIRT2377460	hsa-miR-934	CLIP-seq
MIRT2669904	hsa-miR-939	CLIP-seq

Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q6P1L6

Protein name

Zinc finger protein 343

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	61 → 101	KRAB box	Family
PF00096	zf-C2H2	269 → 291	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	297 → 319	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	353 → 375	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	381 → 403	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	409 → 431	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	437 → 459	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	465 → 487	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	493 → 515	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	521 → 543	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	549 → 571	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	577 → 599	Zinc finger, C2H2 type	Domain

Sequence

MMLPYPSALGDQYWEEILLPKNGENVETMKKLTQNHKAKGLPSNDTDCPQKKEGKAQIVV
PVTFRDVTVIFTEAEWKRLSPEQRNLYKEVMLENYRNLLSLAEPKPEIYTCSSCLLAFSC
QQFLSQHVLQIFLGLCAENHFHPGNSSPGHWKQQGQQYSHVSCWFENAEGQERGGGSKPW
SARTEERETSRAFPSPLQRQSASPRKGNMVVETEPSSAQRPNPVQLDKGLKELETLRFGA
INCREYEPDHNLESNFITNPRTLLGKKPYICSDCGRSFKDRSTLIRHHRIHSMEKPYVCS
ECGRGFSQKSNLSRHQRTHSEEKPYLCRECGQSFRSKSILNRHQWTHSEEKPYVCSECGR
GFSEKSSFIRHQRTHSGEKPYVCLECGRSFCDKSTLRKHQRIHSGEKPYVCRECGRGFSQ
NSDLIKHQRTHLDEKPYVCRECGRGFCDKSTLIIHERTHSGEKPYVCGECGRGFSRKSLL
LVHQRTHSGEKHYVCRECRRGFSQKSNLIRHQRTHSNEKPYICRECGRGFCDKSTLIVHE
RTHSGEKPYVCSECGRGFSRKSLLLVHQRTHSGEKHYVCRECGRGFSHKSNLIRHQRTH

Sequence length

599

Interactions

View interactions

	Reactome
			Generic Transcription Pathway

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
CONOTRUNCAL HEART MALFORMATIONS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Carcinoma Mucoepidermoid	Associate	25823930	★★★★★ ★☆☆☆☆ Found in Text Mining only
Salivary Gland Neoplasms	Associate	25823930	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZNF343 (zinc finger protein 343)