CENPO (centromere protein O)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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79172 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Centromere protein O |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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CENPO |
Synonyms (NCBI Gene)
Gene synonyms aliases
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CENP-O, ICEN-36, MCM21R |
Chromosome
Chromosome number
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2 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2p23.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a component of the interphase centromere complex. The encoded protein is localized to the centromere throughout the cell cycle and is required for bipolar spindle assembly, chromosome segregation and checkpoint signaling during mitosis. |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9BU64 | ||||||||||
Protein name | Centromere protein O (CENP-O) (Interphase centromere complex protein 36) | ||||||||||
Protein function | Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesiz | ||||||||||
PDB | 7PB8 , 7PKN , 7QOO , 7R5S , 7R5V , 7XHN , 7XHO , 7YWX , 7YYH | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 300 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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