PRRC2A (proline rich coiled-coil 2A)

Gene

• Entrez ID: 7916
• Gene name: Proline rich coiled-coil 2A
• Gene symbol: PRRC2A
• Synonyms (NCBI Gene): BAT2, D6S51, D6S51E, G2
• Chromosome: 6
• Chromosome location: 6p21.33
• Summary: A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This gene has microsatellite repeats which are associated wi

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT005234	hsa-let-7b-5p	pSILAC	18668040
MIRT005234	hsa-let-7b-5p	Proteomics	18668040
MIRT005234	hsa-let-7b-5p	CLASH	23622248
MIRT005234	hsa-let-7b-5p	CLASH	23622248
MIRT005234	hsa-let-7b-5p	CLASH	23622248
MIRT051744	hsa-let-7c-5p	CLASH	23622248
MIRT051617	hsa-let-7e-5p	CLASH	23622248
MIRT050337	hsa-miR-25-3p	CLASH	23622248
MIRT048319	hsa-miR-106a-5p	CLASH	23622248
MIRT046673	hsa-miR-222-3p	CLASH	23622248
MIRT046673	hsa-miR-222-3p	CLASH	23622248
MIRT043314	hsa-miR-331-3p	CLASH	23622248
MIRT041837	hsa-miR-484	CLASH	23622248
MIRT041320	hsa-miR-193b-3p	CLASH	23622248
MIRT040800	hsa-miR-18a-3p	CLASH	23622248
MIRT040729	hsa-miR-92b-3p	CLASH	23622248
MIRT039872	hsa-miR-615-3p	CLASH	23622248
MIRT039872	hsa-miR-615-3p	CLASH	23622248
MIRT038861	hsa-miR-93-3p	CLASH	23622248
MIRT038490	hsa-miR-296-3p	CLASH	23622248
MIRT038238	hsa-miR-330-5p	CLASH	23622248
MIRT038145	hsa-miR-423-5p	CLASH	23622248
MIRT037410	hsa-miR-744-5p	CLASH	23622248
MIRT037162	hsa-miR-877-3p	CLASH	23622248
MIRT036751	hsa-miR-760	CLASH	23622248
MIRT036751	hsa-miR-760	CLASH	23622248
MIRT035936	hsa-miR-1180-3p	CLASH	23622248
MIRT035887	hsa-miR-1303	CLASH	23622248
MIRT615516	hsa-miR-605-5p	HITS-CLIP	23824327
MIRT615515	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT615514	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT615513	hsa-miR-556-3p	HITS-CLIP	23824327
MIRT615516	hsa-miR-605-5p	HITS-CLIP	23824327
MIRT615515	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT615514	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT615513	hsa-miR-556-3p	HITS-CLIP	23824327
MIRT470249	hsa-miR-6753-5p	PAR-CLIP	23592263
MIRT470248	hsa-miR-4779	PAR-CLIP	23592263
MIRT470247	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT470246	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT470245	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT470244	hsa-miR-3179	PAR-CLIP	23592263
MIRT470243	hsa-miR-5008-5p	PAR-CLIP	23592263
MIRT470242	hsa-miR-6089	PAR-CLIP	23592263
MIRT470241	hsa-miR-3202	PAR-CLIP	23592263
MIRT470240	hsa-miR-765	PAR-CLIP	23592263
MIRT470239	hsa-miR-874-5p	PAR-CLIP	23592263
MIRT470238	hsa-miR-4747-5p	PAR-CLIP	23592263
MIRT470237	hsa-miR-5196-5p	PAR-CLIP	23592263
MIRT470236	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT470235	hsa-miR-4271	PAR-CLIP	23592263
MIRT470234	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT470233	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT470232	hsa-miR-3144-5p	PAR-CLIP	23592263
MIRT470231	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT470230	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT470229	hsa-miR-5698	PAR-CLIP	23592263
MIRT470228	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT470227	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT470226	hsa-miR-4316	PAR-CLIP	23592263
MIRT439890	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439890	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT615516	hsa-miR-605-5p	HITS-CLIP	23824327
MIRT615515	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT615514	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT615513	hsa-miR-556-3p	HITS-CLIP	23824327
MIRT615516	hsa-miR-605-5p	HITS-CLIP	23824327
MIRT615515	hsa-miR-500a-5p	HITS-CLIP	23824327
MIRT615514	hsa-miR-501-5p	HITS-CLIP	23824327
MIRT615513	hsa-miR-556-3p	HITS-CLIP	23824327
MIRT470249	hsa-miR-6753-5p	PAR-CLIP	23592263
MIRT470248	hsa-miR-4779	PAR-CLIP	23592263
MIRT470247	hsa-miR-6783-5p	PAR-CLIP	23592263
MIRT470246	hsa-miR-4716-3p	PAR-CLIP	23592263
MIRT470245	hsa-miR-6794-5p	PAR-CLIP	23592263
MIRT470244	hsa-miR-3179	PAR-CLIP	23592263
MIRT470243	hsa-miR-5008-5p	PAR-CLIP	23592263
MIRT470242	hsa-miR-6089	PAR-CLIP	23592263
MIRT470241	hsa-miR-3202	PAR-CLIP	23592263
MIRT470240	hsa-miR-765	PAR-CLIP	23592263
MIRT470239	hsa-miR-874-5p	PAR-CLIP	23592263
MIRT470238	hsa-miR-4747-5p	PAR-CLIP	23592263
MIRT470237	hsa-miR-5196-5p	PAR-CLIP	23592263
MIRT470236	hsa-miR-7106-5p	PAR-CLIP	23592263
MIRT470235	hsa-miR-4271	PAR-CLIP	23592263
MIRT470234	hsa-miR-4725-3p	PAR-CLIP	23592263
MIRT470233	hsa-miR-6780b-5p	PAR-CLIP	23592263
MIRT470232	hsa-miR-3144-5p	PAR-CLIP	23592263
MIRT470231	hsa-miR-6825-5p	PAR-CLIP	23592263
MIRT470230	hsa-miR-4723-5p	PAR-CLIP	23592263
MIRT470229	hsa-miR-5698	PAR-CLIP	23592263
MIRT470228	hsa-miR-6870-5p	PAR-CLIP	23592263
MIRT470227	hsa-miR-7111-5p	PAR-CLIP	23592263
MIRT470226	hsa-miR-4316	PAR-CLIP	23592263
MIRT1267345	hsa-miR-1915	CLIP-seq
MIRT1267346	hsa-miR-4323	CLIP-seq
MIRT1267347	hsa-miR-495	CLIP-seq
MIRT1267345	hsa-miR-1915	CLIP-seq
MIRT1267346	hsa-miR-4323	CLIP-seq
MIRT1267347	hsa-miR-495	CLIP-seq
MIRT1267347	hsa-miR-495	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005515	Function	Protein binding	IPI	16713569, 20195357
GO:0005654	Component	Nucleoplasm	IDA
GO:0005829	Component	Cytosol	IDA
GO:0005886	Component	Plasma membrane	IDA
GO:0016020	Component	Membrane	HDA	19946888
GO:0030154	Process	Cell differentiation	IBA	21873635
GO:0070062	Component	Extracellular exosome	HDA	19056867

Other IDs

• MIM: 142580
• HGNC: 13918
• e!Ensembl: ENSG00000204469

Protein

• UniProt ID: P48634
• Protein name: Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
• Protein function: May play a role in the regulation of pre-mRNA splicing.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF07001	BAT2_N	1 → 189	BAT2 N-terminus	Family

• Tissue specificity: TISSUE SPECIFICITY: Limited to cell-lines of leukemic origin.
• Sequence:

  MSDRSGPTAKGKDGKKYSSLNLFDTYKGKSLEIQKPAVAPRHGLQSLGKVAIARRMPPPA
  NLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQTPASN
  QPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAAGDQD
  KAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGP
  PQFPPYRGMMPPFMYPPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEP
  VGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRD
  SQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHRGPA
  GNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQE
  ERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAP
  TPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPE
  PPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQ
  QHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFD
  PRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRER
  GTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPG
  FPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTGPEAGR
  KPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTK
  VEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGP
  TSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPR
  GRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPP
  PPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTG
  PLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRL
  KQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEE
  WETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDL
  SKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRS
  RPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHK
  PGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKR
  RERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSR
  KSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAA
  EGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQR
  TDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWE
  LLPSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPN
  SGGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGV
  LYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQML
  LPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARP
  FPASLGRAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGV
  FRTQRVDLYQQASPPDALRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEPGLPPPR

• Sequence length: 2157

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Breast cancer	Malignant neoplasm of breast	rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158, rs80357524, rs80357115, rs80357945, rs80357729, rs80357609, rs80357259, rs80357981, rs80358063, rs80357389, rs80356862, rs80359876, rs80357580, rs80358053, rs80358089, rs80187739, rs397507241, rs80358069, rs80357590, rs80357284, rs80357941, rs80359261, rs80359272, rs80359276, rs276174813, rs80358474, rs80359316, rs1555282969, rs80359388, rs80359499, rs80359505, rs80359520, rs80359526, rs80359533, rs56253082, rs80358824, rs80359554, rs80359636, rs80359651, rs80359659, rs80359011, rs80359012, rs80359013, rs80359718, rs397507410, rs81002812, rs80359730, rs80359152, rs80359159, rs397507419, rs28897759, rs80359211, rs80359775, rs397514577, rs397507584, rs80358435, rs80358456, rs80359340, rs80359343, rs80359365, rs80358579, rs397507670, rs80358593, rs80359406, rs80359444, rs80359454, rs276174853, rs276174854, rs80359483, rs80359537, rs80358815, rs80358843, rs80359558, rs80359560, rs80359594, rs80358893, rs28897743, rs397507900, rs397507906, rs397507918, rs80358971, rs80358981, rs397507941, rs80359030, rs80359035, rs41293511, rs397507396, rs81002806, rs80359112, rs397508006, rs81002893, rs45580035, rs80359760, rs397508051, rs80359772, rs4987049, rs80359777, rs80357770, rs397508867, rs62625303, rs397508874, rs80357506, rs80357287, rs273898674, rs80358042, rs80358083, rs80357058, rs41286296, rs80357960, rs80356945, rs80357223, rs386134270, rs80358116, rs80357856, rs80357424, rs397509050, rs80357485, rs80357966, rs397509067, rs80357310, rs80356866, rs80357260, rs80357437, rs80358023, rs80358086, rs80357133, rs80356993, rs80357997, rs80357239, rs80357227, rs397509243, rs80356969, rs80356959, rs63750617, rs63751319, rs587779315, rs200640585, rs398122546, rs80357543, rs398122687, rs80359328, rs398122779, rs398122783, rs62517194, rs80358029, rs515726060, rs180177103, rs180177111, rs180177133, rs587776527, rs180177135, rs180177136, rs515726117, rs587779813, rs587779909, rs587780024, rs587780100, rs28909982, rs121908698, rs180177100, rs587780210, rs587780240, rs587780639, rs587781269, rs587781353, rs587781471, rs587781658, rs587781697, rs587781730, rs587781894, rs587781948, rs587782005, rs587782011, rs200928781, rs587781558, rs370228071, rs587782245, rs587782401, rs180177110, rs587782504, rs72552322, rs587782531, rs587782620, rs587782680, rs587782774, rs587782818, rs730881411, rs730881389, rs564652222, rs397507768, rs587776419, rs730881868, rs730881940, rs56383036, rs758972589, rs201089102, rs730881348, rs786202608, rs786201886, rs786203318, rs786203775, rs786203714, rs786202033, rs750621215, rs786203884, rs786203650, rs772821016, rs863224521, rs864622223, rs864622655, rs375699023, rs876659572, rs768362387, rs876659535, rs876658957, rs483353072, rs876659435, rs267608041, rs876661113, rs730881369, rs878853535, rs772228129, rs878855122, rs760551339, rs80359596, rs397509222, rs886039630, rs886039683, rs886040828, rs587781799, rs886040374, rs886040649, rs397507967, rs878854957, rs886040043, rs1057517589, rs1060502769, rs866380588, rs863224765, rs1064793243, rs747563556, rs1555074976, rs1064795885, rs753961188, rs1064794708, rs869312772, rs1064793887, rs1131690820, rs1135401928, rs1135401868, rs1135401859, rs1553370324, rs397507630, rs1555283160, rs1555283251, rs1555283262, rs1555283361, rs1555286298, rs1555288462, rs886040950, rs1555289566, rs776323117, rs80357123, rs1555579627, rs1555580697, rs80358054, rs1555593302, rs1328985852, rs763470424, rs1555139694, rs878854697, rs1555461217, rs1555461765, rs774684620, rs766416564, rs1554558613, rs1305740166, rs1555461460, rs1555461407, rs1555461586, rs1555567202, rs1555607022, rs1555069815, rs1442299125, rs1474786480, rs1555084947, rs1555457867, rs141087784, rs1482641121, rs1564830522, rs1565469955, rs1565503137, rs864622613, rs755263466, rs757679199, rs1593903166, rs1597801649, rs1603293306, rs879253880, rs80358754, rs1597062038, rs45494092, rs1603275367, rs887358871, rs1597091518, rs1966967065, rs1064793049, rs2082872908, rs2085078278, rs2072475243
Diabetes mellitus	Diabetes Mellitus, Insulin-Dependent	rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237, rs80356613, rs387906407, rs151344623, rs28938469, rs28936371, rs137852672, rs80356637, rs80356642, rs80356653, rs137852673, rs137852674, rs80356634, rs80356651, rs193929360, rs137853334, rs137853335, rs137853336, rs1600731198, rs137853338, rs121964882, rs121964883, rs387906511, rs121964884, rs121964885, rs2147483647, rs387906512, rs121964887, rs121964888, rs121964889, rs121964890, rs121964891, rs28934878, rs74315383, rs121964893, rs886037620, rs886037621, rs121434593, rs121913150, rs587776825, rs137853236, rs2135842335, rs137853237, rs137853238, rs2135818776, rs1566092470, rs1463923467, rs137853243, rs137853244, rs2135839114, rs137853245, rs2135847417, rs121918407, rs104894005, rs104894006, rs80356655, rs104894008, rs104894009, rs104894010, rs104894011, rs80356654, rs104894016, rs193929376, rs193929374, rs193929375, rs193929373, rs80356669, rs80356664, rs193929366, rs1048095, rs193929355, rs193929356, rs1259467443, rs104893642, rs387906777, rs193922396, rs193922400, rs193922401, rs137852676, rs193922407, rs193922638, rs193922257, rs193922258, rs193922259, rs193922260, rs193922261, rs193922262, rs193922263, rs193922264, rs193922265, rs193922268, rs193921338, rs193922269, rs193922272, rs193922273, rs193922275, rs193922278, rs193922279, rs193922280, rs193922281, rs193922282, rs193922283, rs193922284, rs193922286, rs193922287, rs193922289, rs193922291, rs193922295, rs193922297, rs193922300, rs193922302, rs193922303, rs193922308, rs193922313, rs193922314, rs144723656, rs193922315, rs193922316, rs193922317, rs148311934, rs193922319, rs193922320, rs193922326, rs193922329, rs193922330, rs193922331, rs193922335, rs193922336, rs193922338, rs193922340, rs193922341, rs193922471, rs193922475, rs193922476, rs193922479, rs80356663, rs193922355, rs193922356, rs193922576, rs193922578, rs193922582, rs193922588, rs193922592, rs193922594, rs193922596, rs386134267, rs193922598, rs193922599, rs193922600, rs193922604, rs193922605, rs397514580, rs397515519, rs267601516, rs587780343, rs587780345, rs587780346, rs587780347, rs587780357, rs148954387, rs587783672, rs587783669, rs786204676, rs794727236, rs151344624, rs794727775, rs794727839, rs199946797, rs869320673, rs796065047, rs759072800, rs797045595, rs797045209, rs797045207, rs797045213, rs863225280, rs149703259, rs864321656, rs139964066, rs777870079, rs878853246, rs769268803, rs886039380, rs886041392, rs886041391, rs886042610, rs143064649, rs1057516192, rs746480424, rs1057516281, rs576684889, rs754728827, rs1057520291, rs1057520779, rs893256143, rs1057520504, rs1057524790, rs1057524902, rs1057524904, rs1057524905, rs764232985, rs1064793998, rs1064794268, rs769086289, rs369429452, rs1085307913, rs1131691416, rs765432081, rs1131692182, rs748749585, rs1554335441, rs762263694, rs1312678560, rs767565869, rs1375656631, rs1554335391, rs1360415315, rs1554335616, rs1554335752, rs1554909277, rs769518471, rs757171524, rs768951263, rs762703502, rs1555212248, rs1555212359, rs1555813319, rs1555816654, rs371977235, rs1415041911, rs1554334894, rs1260178539, rs1554335421, rs1555211904, rs779184183, rs1554335564, rs200670692, rs1400535021, rs1554334872, rs1555212749, rs1553876668, rs1553878211, rs954727530, rs1554924035, rs372307320, rs925231098, rs1554913069, rs1554933565, rs766431403, rs746714109, rs751279984, rs770664202, rs1008906426, rs758844607, rs1554924540, rs1566092307, rs753998395, rs1565885935, rs1167124132, rs1376796469, rs556436603, rs1562715657, rs1486280029, rs1564869850, rs755259997, rs769569410, rs1172328722, rs1286294151, rs1375557127, rs1568731279, rs1562715426, rs556581174, rs1564865302, rs1565886545, rs1568724014, rs1392795567, rs781260712, rs1562719705, rs1382448285, rs1564977373, rs750586210, rs1598842892, rs1583592247, rs780612692, rs1593060859, rs1476637197, rs751279776, rs1593060890, rs1191912908, rs1167675604, rs1583601110, rs1593058932, rs778611627, rs753296261	17632545
Multiple sclerosis	Multiple Sclerosis	rs104895219, rs483353022, rs483353023, rs483353028, rs483353029, rs483353024, rs483353030, rs3207617, rs483353031, rs483353032, rs483353033, rs483353034, rs483353035, rs483353036, rs483353039, rs483353038, rs61731956, rs568165874, rs767480544	17660530
Myasthenia gravis	Myasthenia Gravis	rs5030818, rs121912815, rs121912817, rs121912818, rs121912821, rs75466054, rs121912822, rs121912823, rs794727516, rs764497513, rs376808313, rs1279554995, rs1554802792, rs369251527, rs372760913, rs1554802808, rs769234940, rs201439531, rs1272947184, rs757303526, rs760936252, rs1590576560, rs1838635262	23055271
Rheumatoid arthritis	Rheumatoid Arthritis	rs587776843	21156761, 17804836, 19503088
Schizophrenia	Schizophrenia	rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346, rs863223347, rs863223351, rs863223352, rs61734270, rs797045205, rs869312829, rs869312830, rs770913157, rs869312832, rs869312831, rs781720548, rs1262969313	28540026

Unknown
Disease term	Disease name	Evidence	References	Source
Mental depression	Major Depressive Disorder		29662059	ClinVar
Cervical Cancer	Cervical Cancer	Our screens identified 10 miRNAs that enhance fitness of HeLa cells and have been reported to be up-regulated in cervical cancer (Table2).		GWAS, CBGDA
Anxiety Disorder	Anxiety Disorder			GWAS
Takayasu Arteritis	Takayasu Arteritis			GWAS
Irritable Bowel Syndrome	Irritable Bowel Syndrome			GWAS
Hypertension	Hypertension			GWAS
Diabetes	Diabetes			GWAS
Inflammatory Bowel Disease	Inflammatory Bowel Disease			GWAS
Psoriasis	Psoriasis			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Alzheimer Disease	Associate	35640139
Breast Neoplasms	Associate	23079975
Carcinogenesis	Associate	25937444
Carcinoma Squamous Cell	Associate	23221128
Cardiovascular Diseases	Associate	34996442
Cataract	Associate	30335004
Celiac Disease	Associate	28282431
Coronary Aneurysm	Associate	20626023
Diabetes Mellitus Type 1	Stimulate	35784577
Diabetes Mellitus Type 1	Associate	35784577
Diabetes Mellitus Type 2	Associate	25093408
Diabetic Retinopathy	Associate	30335004
Dyslipidemias	Associate	34996442
Hypertensive Retinopathy	Associate	30335004
Lung Neoplasms	Associate	23221128, 25937444
Lupus Nephritis	Associate	28754791
Lymphoma B Cell	Inhibit	23047821
Lymphoma B Cell	Associate	23047821
Lymphoma Non Hodgkin	Associate	17827388, 23047821, 28282431
Mucocutaneous Lymph Node Syndrome	Associate	20626023
Obesity	Associate	20616199
Primary Ovarian Insufficiency	Associate	34996442
Stroke	Associate	19023099
Triple Negative Breast Neoplasms	Associate	23079975