Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	79139
Gene name Gene Name - the full gene name approved by the HGNC.	Derlin 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	DERL1
Synonyms (NCBI Gene) Gene synonyms aliases	DER-1, DER1, derlin-1
Chromosome Chromosome number	8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	8q24.13
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradatio

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miRTarBase ID	miRNA	Experiments	Reference
MIRT000172	hsa-miR-21-5p	Luciferase reporter assay, Quantitative proteomic approach	19253296
MIRT028468	hsa-miR-30a-5p	Proteomics	18668040
MIRT000172	hsa-miR-21-5p	Microarray	18591254
MIRT031154	hsa-miR-19b-3p	Sequencing	20371350
MIRT050045	hsa-miR-26b-5p	CLASH	23622248
MIRT497912	hsa-miR-139-5p	PAR-CLIP	22291592
MIRT727879	hsa-miR-27a-3p	HITS-CLIP	22473208
MIRT727878	hsa-miR-27b-3p	HITS-CLIP	22473208
MIRT497912	hsa-miR-139-5p	PAR-CLIP	22291592
MIRT933070	hsa-miR-1200	CLIP-seq
MIRT933071	hsa-miR-1224-3p	CLIP-seq
MIRT933072	hsa-miR-1253	CLIP-seq
MIRT933073	hsa-miR-1273d	CLIP-seq
MIRT933074	hsa-miR-1305	CLIP-seq
MIRT933075	hsa-miR-1323	CLIP-seq
MIRT933076	hsa-miR-181a	CLIP-seq
MIRT933077	hsa-miR-181b	CLIP-seq
MIRT933078	hsa-miR-181c	CLIP-seq
MIRT933079	hsa-miR-181d	CLIP-seq
MIRT933080	hsa-miR-182	CLIP-seq
MIRT933081	hsa-miR-2053	CLIP-seq
MIRT933082	hsa-miR-2116	CLIP-seq
MIRT933083	hsa-miR-219-5p	CLIP-seq
MIRT933084	hsa-miR-223	CLIP-seq
MIRT933085	hsa-miR-27a	CLIP-seq
MIRT933086	hsa-miR-27b	CLIP-seq
MIRT933087	hsa-miR-302a	CLIP-seq
MIRT933088	hsa-miR-302b	CLIP-seq
MIRT933089	hsa-miR-302c	CLIP-seq
MIRT933090	hsa-miR-302d	CLIP-seq
MIRT933091	hsa-miR-302e	CLIP-seq
MIRT933092	hsa-miR-3074-5p	CLIP-seq
MIRT933093	hsa-miR-3140-5p	CLIP-seq
MIRT933094	hsa-miR-3152-3p	CLIP-seq
MIRT933095	hsa-miR-3190	CLIP-seq
MIRT933096	hsa-miR-3192	CLIP-seq
MIRT933097	hsa-miR-3613-3p	CLIP-seq
MIRT933098	hsa-miR-3658	CLIP-seq
MIRT933099	hsa-miR-3664-3p	CLIP-seq
MIRT933100	hsa-miR-3689a-3p	CLIP-seq
MIRT933101	hsa-miR-3689c	CLIP-seq
MIRT933102	hsa-miR-372	CLIP-seq
MIRT933103	hsa-miR-373	CLIP-seq
MIRT933104	hsa-miR-375	CLIP-seq
MIRT933105	hsa-miR-382	CLIP-seq
MIRT933106	hsa-miR-412	CLIP-seq
MIRT933107	hsa-miR-4261	CLIP-seq
MIRT933108	hsa-miR-4262	CLIP-seq
MIRT933109	hsa-miR-4273	CLIP-seq
MIRT933110	hsa-miR-4276	CLIP-seq
MIRT933111	hsa-miR-4282	CLIP-seq
MIRT933112	hsa-miR-4302	CLIP-seq
MIRT933113	hsa-miR-4328	CLIP-seq
MIRT933114	hsa-miR-4445	CLIP-seq
MIRT933115	hsa-miR-4470	CLIP-seq
MIRT933116	hsa-miR-4474-3p	CLIP-seq
MIRT933117	hsa-miR-4496	CLIP-seq
MIRT933118	hsa-miR-4509	CLIP-seq
MIRT933119	hsa-miR-450b-5p	CLIP-seq
MIRT933120	hsa-miR-4517	CLIP-seq
MIRT933121	hsa-miR-4525	CLIP-seq
MIRT933122	hsa-miR-4659a-3p	CLIP-seq
MIRT933123	hsa-miR-4659b-3p	CLIP-seq
MIRT933124	hsa-miR-4662a-5p	CLIP-seq
MIRT933125	hsa-miR-4676-5p	CLIP-seq
MIRT933126	hsa-miR-4677-5p	CLIP-seq
MIRT933127	hsa-miR-4709-5p	CLIP-seq
MIRT933128	hsa-miR-4714-3p	CLIP-seq
MIRT933129	hsa-miR-4728-5p	CLIP-seq
MIRT933130	hsa-miR-4738-3p	CLIP-seq
MIRT933131	hsa-miR-4744	CLIP-seq
MIRT933132	hsa-miR-4752	CLIP-seq
MIRT933133	hsa-miR-4757-5p	CLIP-seq
MIRT933134	hsa-miR-4776-3p	CLIP-seq
MIRT933135	hsa-miR-4782-3p	CLIP-seq
MIRT933136	hsa-miR-4799-5p	CLIP-seq
MIRT933137	hsa-miR-494	CLIP-seq
MIRT933138	hsa-miR-507	CLIP-seq
MIRT933139	hsa-miR-508-3p	CLIP-seq
MIRT933140	hsa-miR-513a-5p	CLIP-seq
MIRT933141	hsa-miR-519a	CLIP-seq
MIRT933142	hsa-miR-519b-3p	CLIP-seq
MIRT933143	hsa-miR-519c-3p	CLIP-seq
MIRT933144	hsa-miR-520a-3p	CLIP-seq
MIRT933145	hsa-miR-520b	CLIP-seq
MIRT933146	hsa-miR-520c-3p	CLIP-seq
MIRT933147	hsa-miR-520d-3p	CLIP-seq
MIRT933148	hsa-miR-520e	CLIP-seq
MIRT933149	hsa-miR-548aa	CLIP-seq
MIRT933150	hsa-miR-548o	CLIP-seq
MIRT933151	hsa-miR-548t	CLIP-seq
MIRT933152	hsa-miR-548u	CLIP-seq
MIRT933153	hsa-miR-557	CLIP-seq
MIRT933154	hsa-miR-575	CLIP-seq
MIRT933155	hsa-miR-580	CLIP-seq
MIRT933156	hsa-miR-590-3p	CLIP-seq
MIRT933157	hsa-miR-649	CLIP-seq
MIRT933158	hsa-miR-660	CLIP-seq
MIRT933159	hsa-miR-758	CLIP-seq
MIRT933160	hsa-miR-873	CLIP-seq
MIRT933161	hsa-miR-1202	CLIP-seq
MIRT933162	hsa-miR-1245b-3p	CLIP-seq
MIRT933073	hsa-miR-1273d	CLIP-seq
MIRT933163	hsa-miR-1291	CLIP-seq
MIRT933164	hsa-miR-132	CLIP-seq
MIRT933165	hsa-miR-146b-3p	CLIP-seq
MIRT933080	hsa-miR-182	CLIP-seq
MIRT933166	hsa-miR-19a	CLIP-seq
MIRT933167	hsa-miR-19b	CLIP-seq
MIRT933082	hsa-miR-2116	CLIP-seq
MIRT933168	hsa-miR-212	CLIP-seq
MIRT933083	hsa-miR-219-5p	CLIP-seq
MIRT933084	hsa-miR-223	CLIP-seq
MIRT933085	hsa-miR-27a	CLIP-seq
MIRT933086	hsa-miR-27b	CLIP-seq
MIRT933169	hsa-miR-3065-5p	CLIP-seq
MIRT933170	hsa-miR-3157-3p	CLIP-seq
MIRT933171	hsa-miR-3160-5p	CLIP-seq
MIRT933172	hsa-miR-3163	CLIP-seq
MIRT933173	hsa-miR-3173-5p	CLIP-seq
MIRT933095	hsa-miR-3190	CLIP-seq
MIRT933174	hsa-miR-3194-5p	CLIP-seq
MIRT933175	hsa-miR-328	CLIP-seq
MIRT933176	hsa-miR-345	CLIP-seq
MIRT933177	hsa-miR-3545-3p	CLIP-seq
MIRT933178	hsa-miR-374c	CLIP-seq
MIRT933104	hsa-miR-375	CLIP-seq
MIRT933179	hsa-miR-3942-3p	CLIP-seq
MIRT933180	hsa-miR-3972	CLIP-seq
MIRT933106	hsa-miR-412	CLIP-seq
MIRT933181	hsa-miR-4267	CLIP-seq
MIRT933182	hsa-miR-4268	CLIP-seq
MIRT933109	hsa-miR-4273	CLIP-seq
MIRT933183	hsa-miR-4311	CLIP-seq
MIRT933184	hsa-miR-4323	CLIP-seq
MIRT933113	hsa-miR-4328	CLIP-seq
MIRT933185	hsa-miR-4420	CLIP-seq
MIRT933114	hsa-miR-4445	CLIP-seq
MIRT933186	hsa-miR-4448	CLIP-seq
MIRT933115	hsa-miR-4470	CLIP-seq
MIRT933116	hsa-miR-4474-3p	CLIP-seq
MIRT933187	hsa-miR-4494	CLIP-seq
MIRT933119	hsa-miR-450b-5p	CLIP-seq
MIRT933120	hsa-miR-4517	CLIP-seq
MIRT933188	hsa-miR-4530	CLIP-seq
MIRT933189	hsa-miR-4539	CLIP-seq
MIRT933190	hsa-miR-4645-3p	CLIP-seq
MIRT933126	hsa-miR-4677-5p	CLIP-seq
MIRT933191	hsa-miR-4696	CLIP-seq
MIRT933192	hsa-miR-4701-5p	CLIP-seq
MIRT933193	hsa-miR-4709-3p	CLIP-seq
MIRT933130	hsa-miR-4738-3p	CLIP-seq
MIRT933132	hsa-miR-4752	CLIP-seq
MIRT933194	hsa-miR-4771	CLIP-seq
MIRT933135	hsa-miR-4782-3p	CLIP-seq
MIRT933195	hsa-miR-499a-5p	CLIP-seq
MIRT933138	hsa-miR-507	CLIP-seq
MIRT933139	hsa-miR-508-3p	CLIP-seq
MIRT933140	hsa-miR-513a-5p	CLIP-seq
MIRT933149	hsa-miR-548aa	CLIP-seq
MIRT933153	hsa-miR-557	CLIP-seq
MIRT933155	hsa-miR-580	CLIP-seq
MIRT933196	hsa-miR-588	CLIP-seq
MIRT933197	hsa-miR-598	CLIP-seq
MIRT933198	hsa-miR-622	CLIP-seq
MIRT933199	hsa-miR-655	CLIP-seq
MIRT933158	hsa-miR-660	CLIP-seq
MIRT933200	hsa-miR-663b	CLIP-seq
MIRT933159	hsa-miR-758	CLIP-seq
MIRT933201	hsa-miR-874	CLIP-seq
MIRT933202	hsa-miR-922	CLIP-seq
MIRT1976249	hsa-miR-1208	CLIP-seq
MIRT933072	hsa-miR-1253	CLIP-seq
MIRT933164	hsa-miR-132	CLIP-seq
MIRT933075	hsa-miR-1323	CLIP-seq
MIRT933080	hsa-miR-182	CLIP-seq
MIRT1976250	hsa-miR-200b	CLIP-seq
MIRT1976251	hsa-miR-200c	CLIP-seq
MIRT933082	hsa-miR-2116	CLIP-seq
MIRT933168	hsa-miR-212	CLIP-seq
MIRT933083	hsa-miR-219-5p	CLIP-seq
MIRT933084	hsa-miR-223	CLIP-seq
MIRT933085	hsa-miR-27a	CLIP-seq
MIRT933086	hsa-miR-27b	CLIP-seq
MIRT933094	hsa-miR-3152-3p	CLIP-seq
MIRT1976252	hsa-miR-3153	CLIP-seq
MIRT933171	hsa-miR-3160-5p	CLIP-seq
MIRT933172	hsa-miR-3163	CLIP-seq
MIRT933096	hsa-miR-3192	CLIP-seq
MIRT1976253	hsa-miR-3685	CLIP-seq
MIRT933100	hsa-miR-3689a-3p	CLIP-seq
MIRT933101	hsa-miR-3689c	CLIP-seq
MIRT933104	hsa-miR-375	CLIP-seq
MIRT1976254	hsa-miR-384	CLIP-seq
MIRT933179	hsa-miR-3942-3p	CLIP-seq
MIRT933106	hsa-miR-412	CLIP-seq
MIRT933182	hsa-miR-4268	CLIP-seq
MIRT933109	hsa-miR-4273	CLIP-seq
MIRT1976255	hsa-miR-429	CLIP-seq
MIRT933113	hsa-miR-4328	CLIP-seq
MIRT1976256	hsa-miR-4436b-3p	CLIP-seq
MIRT933114	hsa-miR-4445	CLIP-seq
MIRT1976257	hsa-miR-4447	CLIP-seq
MIRT933186	hsa-miR-4448	CLIP-seq
MIRT933115	hsa-miR-4470	CLIP-seq
MIRT1976258	hsa-miR-4472	CLIP-seq
MIRT933116	hsa-miR-4474-3p	CLIP-seq
MIRT1976259	hsa-miR-4481	CLIP-seq
MIRT933119	hsa-miR-450b-5p	CLIP-seq
MIRT933120	hsa-miR-4517	CLIP-seq
MIRT1976260	hsa-miR-452	CLIP-seq
MIRT933124	hsa-miR-4662a-5p	CLIP-seq
MIRT1976261	hsa-miR-4668-5p	CLIP-seq
MIRT1976262	hsa-miR-4676-3p	CLIP-seq
MIRT933125	hsa-miR-4676-5p	CLIP-seq
MIRT933126	hsa-miR-4677-5p	CLIP-seq
MIRT1976263	hsa-miR-4691-3p	CLIP-seq
MIRT933127	hsa-miR-4709-5p	CLIP-seq
MIRT933129	hsa-miR-4728-5p	CLIP-seq
MIRT1976264	hsa-miR-4745-5p	CLIP-seq
MIRT933134	hsa-miR-4776-3p	CLIP-seq
MIRT933135	hsa-miR-4782-3p	CLIP-seq
MIRT1976265	hsa-miR-4789-3p	CLIP-seq
MIRT1976266	hsa-miR-499-3p	CLIP-seq
MIRT1976267	hsa-miR-499a-3p	CLIP-seq
MIRT933138	hsa-miR-507	CLIP-seq
MIRT933139	hsa-miR-508-3p	CLIP-seq
MIRT933140	hsa-miR-513a-5p	CLIP-seq
MIRT933150	hsa-miR-548o	CLIP-seq
MIRT933153	hsa-miR-557	CLIP-seq
MIRT933154	hsa-miR-575	CLIP-seq
MIRT933156	hsa-miR-590-3p	CLIP-seq
MIRT933197	hsa-miR-598	CLIP-seq
MIRT933198	hsa-miR-622	CLIP-seq
MIRT933157	hsa-miR-649	CLIP-seq
MIRT933159	hsa-miR-758	CLIP-seq
MIRT1976268	hsa-miR-888	CLIP-seq
MIRT933082	hsa-miR-2116	CLIP-seq
MIRT933084	hsa-miR-223	CLIP-seq
MIRT2211674	hsa-miR-2278	CLIP-seq
MIRT933085	hsa-miR-27a	CLIP-seq
MIRT933086	hsa-miR-27b	CLIP-seq
MIRT2211675	hsa-miR-28-5p	CLIP-seq
MIRT2211676	hsa-miR-3121-3p	CLIP-seq
MIRT2211677	hsa-miR-3139	CLIP-seq
MIRT933094	hsa-miR-3152-3p	CLIP-seq
MIRT933095	hsa-miR-3190	CLIP-seq
MIRT2211678	hsa-miR-3662	CLIP-seq
MIRT933099	hsa-miR-3664-3p	CLIP-seq
MIRT2211679	hsa-miR-3667-3p	CLIP-seq
MIRT933178	hsa-miR-374c	CLIP-seq
MIRT933104	hsa-miR-375	CLIP-seq
MIRT933106	hsa-miR-412	CLIP-seq
MIRT933107	hsa-miR-4261	CLIP-seq
MIRT933109	hsa-miR-4273	CLIP-seq
MIRT2211680	hsa-miR-4297	CLIP-seq
MIRT933112	hsa-miR-4302	CLIP-seq
MIRT933113	hsa-miR-4328	CLIP-seq
MIRT1976256	hsa-miR-4436b-3p	CLIP-seq
MIRT933117	hsa-miR-4496	CLIP-seq
MIRT933119	hsa-miR-450b-5p	CLIP-seq
MIRT1976260	hsa-miR-452	CLIP-seq
MIRT2211681	hsa-miR-4655-3p	CLIP-seq
MIRT933124	hsa-miR-4662a-5p	CLIP-seq
MIRT1976261	hsa-miR-4668-5p	CLIP-seq
MIRT1976262	hsa-miR-4676-3p	CLIP-seq
MIRT933125	hsa-miR-4676-5p	CLIP-seq
MIRT933126	hsa-miR-4677-5p	CLIP-seq
MIRT933127	hsa-miR-4709-5p	CLIP-seq
MIRT933130	hsa-miR-4738-3p	CLIP-seq
MIRT933132	hsa-miR-4752	CLIP-seq
MIRT933136	hsa-miR-4799-5p	CLIP-seq
MIRT2211682	hsa-miR-495	CLIP-seq
MIRT933138	hsa-miR-507	CLIP-seq
MIRT933140	hsa-miR-513a-5p	CLIP-seq
MIRT2211683	hsa-miR-516a-3p	CLIP-seq
MIRT933151	hsa-miR-548t	CLIP-seq
MIRT933153	hsa-miR-557	CLIP-seq
MIRT2211684	hsa-miR-558	CLIP-seq
MIRT933154	hsa-miR-575	CLIP-seq
MIRT933155	hsa-miR-580	CLIP-seq
MIRT933156	hsa-miR-590-3p	CLIP-seq
MIRT933197	hsa-miR-598	CLIP-seq
MIRT933157	hsa-miR-649	CLIP-seq
MIRT933199	hsa-miR-655	CLIP-seq
MIRT933200	hsa-miR-663b	CLIP-seq
MIRT2211685	hsa-miR-708	CLIP-seq
MIRT933160	hsa-miR-873	CLIP-seq
MIRT933084	hsa-miR-223	CLIP-seq
MIRT933113	hsa-miR-4328	CLIP-seq
MIRT933119	hsa-miR-450b-5p	CLIP-seq
MIRT1976261	hsa-miR-4668-5p	CLIP-seq
MIRT933138	hsa-miR-507	CLIP-seq
MIRT933153	hsa-miR-557	CLIP-seq
MIRT2442101	hsa-miR-330-3p	CLIP-seq
MIRT2442102	hsa-miR-606	CLIP-seq
MIRT933161	hsa-miR-1202	CLIP-seq
MIRT2515380	hsa-miR-1245b-5p	CLIP-seq
MIRT933072	hsa-miR-1253	CLIP-seq
MIRT933073	hsa-miR-1273d	CLIP-seq
MIRT933164	hsa-miR-132	CLIP-seq
MIRT933075	hsa-miR-1323	CLIP-seq
MIRT2515381	hsa-miR-137	CLIP-seq
MIRT933076	hsa-miR-181a	CLIP-seq
MIRT933077	hsa-miR-181b	CLIP-seq
MIRT933078	hsa-miR-181c	CLIP-seq
MIRT933079	hsa-miR-181d	CLIP-seq
MIRT933080	hsa-miR-182	CLIP-seq
MIRT1976250	hsa-miR-200b	CLIP-seq
MIRT1976251	hsa-miR-200c	CLIP-seq
MIRT2515382	hsa-miR-2052	CLIP-seq
MIRT933081	hsa-miR-2053	CLIP-seq
MIRT933168	hsa-miR-212	CLIP-seq
MIRT933083	hsa-miR-219-5p	CLIP-seq
MIRT2515383	hsa-miR-22	CLIP-seq
MIRT2515384	hsa-miR-221	CLIP-seq
MIRT2515385	hsa-miR-222	CLIP-seq
MIRT2515386	hsa-miR-299-3p	CLIP-seq
MIRT2515387	hsa-miR-299-5p	CLIP-seq
MIRT2515388	hsa-miR-3115	CLIP-seq
MIRT2515389	hsa-miR-3125	CLIP-seq
MIRT2515390	hsa-miR-3142	CLIP-seq
MIRT2515391	hsa-miR-3145-5p	CLIP-seq
MIRT2515392	hsa-miR-3151	CLIP-seq
MIRT933094	hsa-miR-3152-3p	CLIP-seq
MIRT2515393	hsa-miR-3152-5p	CLIP-seq
MIRT933171	hsa-miR-3160-5p	CLIP-seq
MIRT933172	hsa-miR-3163	CLIP-seq
MIRT2515394	hsa-miR-3175	CLIP-seq
MIRT2515395	hsa-miR-3180-5p	CLIP-seq
MIRT2515396	hsa-miR-3185	CLIP-seq
MIRT933174	hsa-miR-3194-5p	CLIP-seq
MIRT2515397	hsa-miR-3200-5p	CLIP-seq
MIRT2515398	hsa-miR-320a	CLIP-seq
MIRT2515399	hsa-miR-320b	CLIP-seq
MIRT2515400	hsa-miR-320c	CLIP-seq
MIRT2515401	hsa-miR-320d	CLIP-seq
MIRT2515402	hsa-miR-324-5p	CLIP-seq
MIRT2442101	hsa-miR-330-3p	CLIP-seq
MIRT2515403	hsa-miR-340	CLIP-seq
MIRT2515404	hsa-miR-361-3p	CLIP-seq
MIRT2515405	hsa-miR-3647-3p	CLIP-seq
MIRT933098	hsa-miR-3658	CLIP-seq
MIRT933099	hsa-miR-3664-3p	CLIP-seq
MIRT2515406	hsa-miR-3671	CLIP-seq
MIRT2515407	hsa-miR-3688-5p	CLIP-seq
MIRT2515408	hsa-miR-3916	CLIP-seq
MIRT2515409	hsa-miR-3936	CLIP-seq
MIRT933179	hsa-miR-3942-3p	CLIP-seq
MIRT933180	hsa-miR-3972	CLIP-seq
MIRT2515410	hsa-miR-4251	CLIP-seq
MIRT933107	hsa-miR-4261	CLIP-seq
MIRT933108	hsa-miR-4262	CLIP-seq
MIRT933181	hsa-miR-4267	CLIP-seq
MIRT933182	hsa-miR-4268	CLIP-seq
MIRT933110	hsa-miR-4276	CLIP-seq
MIRT933111	hsa-miR-4282	CLIP-seq
MIRT1976255	hsa-miR-429	CLIP-seq
MIRT933112	hsa-miR-4302	CLIP-seq
MIRT2515411	hsa-miR-4307	CLIP-seq
MIRT2515412	hsa-miR-4312	CLIP-seq
MIRT933184	hsa-miR-4323	CLIP-seq
MIRT2515413	hsa-miR-433	CLIP-seq
MIRT2515414	hsa-miR-4429	CLIP-seq
MIRT2515415	hsa-miR-4434	CLIP-seq
MIRT1976256	hsa-miR-4436b-3p	CLIP-seq
MIRT933114	hsa-miR-4445	CLIP-seq
MIRT1976257	hsa-miR-4447	CLIP-seq
MIRT933186	hsa-miR-4448	CLIP-seq
MIRT2515416	hsa-miR-4453	CLIP-seq
MIRT933115	hsa-miR-4470	CLIP-seq
MIRT1976258	hsa-miR-4472	CLIP-seq
MIRT933117	hsa-miR-4496	CLIP-seq
MIRT2515417	hsa-miR-4516	CLIP-seq
MIRT933120	hsa-miR-4517	CLIP-seq
MIRT933188	hsa-miR-4530	CLIP-seq
MIRT2515418	hsa-miR-4538	CLIP-seq
MIRT933124	hsa-miR-4662a-5p	CLIP-seq
MIRT2515419	hsa-miR-4666-3p	CLIP-seq
MIRT1976261	hsa-miR-4668-5p	CLIP-seq
MIRT933125	hsa-miR-4676-5p	CLIP-seq
MIRT2515420	hsa-miR-4684-3p	CLIP-seq
MIRT933127	hsa-miR-4709-5p	CLIP-seq
MIRT2515421	hsa-miR-4713-5p	CLIP-seq
MIRT2515422	hsa-miR-4715-3p	CLIP-seq
MIRT2515423	hsa-miR-4716-3p	CLIP-seq
MIRT2515424	hsa-miR-4716-5p	CLIP-seq
MIRT2515425	hsa-miR-4731-3p	CLIP-seq
MIRT933194	hsa-miR-4771	CLIP-seq
MIRT2515426	hsa-miR-4772-3p	CLIP-seq
MIRT2515427	hsa-miR-4774-3p	CLIP-seq
MIRT933135	hsa-miR-4782-3p	CLIP-seq
MIRT2515428	hsa-miR-4789-5p	CLIP-seq
MIRT2515429	hsa-miR-4795-5p	CLIP-seq
MIRT2515430	hsa-miR-4801	CLIP-seq
MIRT2515431	hsa-miR-4803	CLIP-seq
MIRT2515432	hsa-miR-491-5p	CLIP-seq
MIRT933137	hsa-miR-494	CLIP-seq
MIRT2211682	hsa-miR-495	CLIP-seq
MIRT933139	hsa-miR-508-3p	CLIP-seq
MIRT2515433	hsa-miR-508-5p	CLIP-seq
MIRT2515434	hsa-miR-511	CLIP-seq
MIRT2211683	hsa-miR-516a-3p	CLIP-seq
MIRT2515435	hsa-miR-518a-5p	CLIP-seq
MIRT2515436	hsa-miR-520a-5p	CLIP-seq
MIRT2515437	hsa-miR-525-5p	CLIP-seq
MIRT2515438	hsa-miR-527	CLIP-seq
MIRT2515439	hsa-miR-539	CLIP-seq
MIRT933149	hsa-miR-548aa	CLIP-seq
MIRT2515440	hsa-miR-548c-3p	CLIP-seq
MIRT933150	hsa-miR-548o	CLIP-seq
MIRT933152	hsa-miR-548u	CLIP-seq
MIRT2515441	hsa-miR-548v	CLIP-seq
MIRT2515442	hsa-miR-553	CLIP-seq
MIRT933154	hsa-miR-575	CLIP-seq
MIRT2515443	hsa-miR-582-5p	CLIP-seq
MIRT933156	hsa-miR-590-3p	CLIP-seq
MIRT933197	hsa-miR-598	CLIP-seq
MIRT2442102	hsa-miR-606	CLIP-seq
MIRT933198	hsa-miR-622	CLIP-seq
MIRT2515444	hsa-miR-625	CLIP-seq
MIRT2515445	hsa-miR-627	CLIP-seq
MIRT933157	hsa-miR-649	CLIP-seq
MIRT933158	hsa-miR-660	CLIP-seq
MIRT933159	hsa-miR-758	CLIP-seq
MIRT2515446	hsa-miR-766	CLIP-seq
MIRT933160	hsa-miR-873	CLIP-seq
MIRT1976268	hsa-miR-888	CLIP-seq
MIRT2515447	hsa-miR-891b	CLIP-seq
MIRT933202	hsa-miR-922	CLIP-seq
MIRT2515448	hsa-miR-924	CLIP-seq
MIRT2515449	hsa-miR-942	CLIP-seq
MIRT2515450	hsa-miR-944	CLIP-seq
MIRT933161	hsa-miR-1202	CLIP-seq
MIRT2515380	hsa-miR-1245b-5p	CLIP-seq
MIRT933073	hsa-miR-1273d	CLIP-seq
MIRT933075	hsa-miR-1323	CLIP-seq
MIRT933080	hsa-miR-182	CLIP-seq
MIRT2515382	hsa-miR-2052	CLIP-seq
MIRT933083	hsa-miR-219-5p	CLIP-seq
MIRT2515383	hsa-miR-22	CLIP-seq
MIRT2515386	hsa-miR-299-3p	CLIP-seq
MIRT2515387	hsa-miR-299-5p	CLIP-seq
MIRT2515388	hsa-miR-3115	CLIP-seq
MIRT2515390	hsa-miR-3142	CLIP-seq
MIRT2515391	hsa-miR-3145-5p	CLIP-seq
MIRT2515393	hsa-miR-3152-5p	CLIP-seq
MIRT933172	hsa-miR-3163	CLIP-seq
MIRT2515394	hsa-miR-3175	CLIP-seq
MIRT2515395	hsa-miR-3180-5p	CLIP-seq
MIRT2515396	hsa-miR-3185	CLIP-seq
MIRT933174	hsa-miR-3194-5p	CLIP-seq
MIRT2515397	hsa-miR-3200-5p	CLIP-seq
MIRT2515398	hsa-miR-320a	CLIP-seq
MIRT2515399	hsa-miR-320b	CLIP-seq
MIRT2515400	hsa-miR-320c	CLIP-seq
MIRT2515401	hsa-miR-320d	CLIP-seq
MIRT2515402	hsa-miR-324-5p	CLIP-seq
MIRT2442101	hsa-miR-330-3p	CLIP-seq
MIRT2515403	hsa-miR-340	CLIP-seq
MIRT2515404	hsa-miR-361-3p	CLIP-seq
MIRT2515405	hsa-miR-3647-3p	CLIP-seq
MIRT2515406	hsa-miR-3671	CLIP-seq
MIRT2515407	hsa-miR-3688-5p	CLIP-seq
MIRT2515409	hsa-miR-3936	CLIP-seq
MIRT933180	hsa-miR-3972	CLIP-seq
MIRT2515410	hsa-miR-4251	CLIP-seq
MIRT933181	hsa-miR-4267	CLIP-seq
MIRT933111	hsa-miR-4282	CLIP-seq
MIRT2515411	hsa-miR-4307	CLIP-seq
MIRT2515412	hsa-miR-4312	CLIP-seq
MIRT933184	hsa-miR-4323	CLIP-seq
MIRT2515414	hsa-miR-4429	CLIP-seq
MIRT2515415	hsa-miR-4434	CLIP-seq
MIRT1976256	hsa-miR-4436b-3p	CLIP-seq
MIRT933114	hsa-miR-4445	CLIP-seq
MIRT2515416	hsa-miR-4453	CLIP-seq
MIRT933115	hsa-miR-4470	CLIP-seq
MIRT2515417	hsa-miR-4516	CLIP-seq
MIRT933120	hsa-miR-4517	CLIP-seq
MIRT933188	hsa-miR-4530	CLIP-seq
MIRT2515418	hsa-miR-4538	CLIP-seq
MIRT1976261	hsa-miR-4668-5p	CLIP-seq
MIRT933125	hsa-miR-4676-5p	CLIP-seq
MIRT2515420	hsa-miR-4684-3p	CLIP-seq
MIRT2515422	hsa-miR-4715-3p	CLIP-seq
MIRT2515423	hsa-miR-4716-3p	CLIP-seq
MIRT2515424	hsa-miR-4716-5p	CLIP-seq
MIRT2515425	hsa-miR-4731-3p	CLIP-seq
MIRT933194	hsa-miR-4771	CLIP-seq
MIRT2515426	hsa-miR-4772-3p	CLIP-seq
MIRT2515427	hsa-miR-4774-3p	CLIP-seq
MIRT933135	hsa-miR-4782-3p	CLIP-seq
MIRT2515429	hsa-miR-4795-5p	CLIP-seq
MIRT2515430	hsa-miR-4801	CLIP-seq
MIRT2515431	hsa-miR-4803	CLIP-seq
MIRT933137	hsa-miR-494	CLIP-seq
MIRT933139	hsa-miR-508-3p	CLIP-seq
MIRT2515433	hsa-miR-508-5p	CLIP-seq
MIRT2211683	hsa-miR-516a-3p	CLIP-seq
MIRT2515435	hsa-miR-518a-5p	CLIP-seq
MIRT2515436	hsa-miR-520a-5p	CLIP-seq
MIRT2515437	hsa-miR-525-5p	CLIP-seq
MIRT2515438	hsa-miR-527	CLIP-seq
MIRT2515439	hsa-miR-539	CLIP-seq
MIRT933149	hsa-miR-548aa	CLIP-seq
MIRT2515440	hsa-miR-548c-3p	CLIP-seq
MIRT933150	hsa-miR-548o	CLIP-seq
MIRT2515442	hsa-miR-553	CLIP-seq
MIRT933154	hsa-miR-575	CLIP-seq
MIRT933156	hsa-miR-590-3p	CLIP-seq
MIRT933197	hsa-miR-598	CLIP-seq
MIRT2442102	hsa-miR-606	CLIP-seq
MIRT2515444	hsa-miR-625	CLIP-seq
MIRT933157	hsa-miR-649	CLIP-seq
MIRT933158	hsa-miR-660	CLIP-seq
MIRT933159	hsa-miR-758	CLIP-seq
MIRT2515446	hsa-miR-766	CLIP-seq
MIRT1976268	hsa-miR-888	CLIP-seq
MIRT2515447	hsa-miR-891b	CLIP-seq
MIRT933202	hsa-miR-922	CLIP-seq
MIRT2515450	hsa-miR-944	CLIP-seq
MIRT933115	hsa-miR-4470	CLIP-seq

Show/Hide all(44)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000839	Component	Hrd1p ubiquitin ligase ERAD-L complex	IBA	21873635
GO:0002020	Function	Protease binding	IPI	25239945
GO:0005047	Function	Signal recognition particle binding	IDA	26565908
GO:0005515	Function	Protein binding	IPI	15215856, 16901789, 17872946, 18555783, 18675248, 19135427, 19275885, 19818707, 24089527, 25239945, 25416956, 29275994, 32296183
GO:0005769	Component	Early endosome	IEA
GO:0005770	Component	Late endosome	IEA
GO:0005783	Component	Endoplasmic reticulum	IDA	15215855, 16186510
GO:0005783	Component	Endoplasmic reticulum	IMP	16449189
GO:0005789	Component	Endoplasmic reticulum membrane	TAS
GO:0006457	Process	Protein folding	TAS
GO:0006986	Process	Response to unfolded protein	IMP	15215855
GO:0016020	Component	Membrane	HDA	19946888
GO:0016021	Component	Integral component of membrane	IDA	15215855
GO:0016032	Process	Viral process	IEA
GO:0016567	Process	Protein ubiquitination	TAS
GO:0030176	Component	Integral component of endoplasmic reticulum membrane	IBA	21873635
GO:0030176	Component	Integral component of endoplasmic reticulum membrane	IDA	15215856
GO:0030433	Process	Ubiquitin-dependent ERAD pathway	IBA	21873635
GO:0030433	Process	Ubiquitin-dependent ERAD pathway	IDA	15215856, 17872946
GO:0030433	Process	Ubiquitin-dependent ERAD pathway	IMP	18555783
GO:0030433	Process	Ubiquitin-dependent ERAD pathway	TAS	22013210
GO:0030968	Process	Endoplasmic reticulum unfolded protein response	IBA	21873635
GO:0030968	Process	Endoplasmic reticulum unfolded protein response	IDA	15215856
GO:0030970	Process	Retrograde protein transport, ER to cytosol	IDA	15215856
GO:0030970	Process	Retrograde protein transport, ER to cytosol	IMP	15215855, 25660456
GO:0031398	Process	Positive regulation of protein ubiquitination	IDA	24089527
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	24019521
GO:0031648	Process	Protein destabilization	IMP	25239945
GO:0032092	Process	Positive regulation of protein binding	IMP	24089527
GO:0036502	Component	Derlin-1-VIMP complex	IDA	15215856
GO:0036503	Process	ERAD pathway	IMP	25239945
GO:0036513	Component	Derlin-1 retrotranslocation complex	IDA	15215856, 17872946, 25239945
GO:0038023	Function	Signaling receptor activity	NAS	15215856
GO:0042288	Function	MHC class I protein binding	IDA	15215855
GO:0042802	Function	Identical protein binding	IPI	16186510
GO:0044322	Component	Endoplasmic reticulum quality control compartment	IEA
GO:0044877	Function	Protein-containing complex binding	IPI	26565908
GO:0045184	Process	Establishment of protein localization	TAS	15215856
GO:0051117	Function	ATPase binding	IPI	16186510, 24089527
GO:0051787	Function	Misfolded protein binding	IBA	21873635
GO:0055085	Process	Transmembrane transport	TAS
GO:0071712	Process	ER-associated misfolded protein catabolic process	IMP	24089527
GO:1990381	Function	Ubiquitin-specific protease binding	IBA	21873635
GO:1990381	Function	Ubiquitin-specific protease binding	IPI	17000876

MIM	HGNC	e!Ensembl
608813	28454	ENSG00000136986

Protein

UniProt ID

Q9BUN8

Protein name

Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1)

Protein function

Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins (PubMed:15215856, PubMed:33658201). Forms homotetramers which encircle a large channel traversing the endoplasmic reticulum (ER) membrane

PDB

5GLF , 7CZB , 7Y4W , 7Y53 , 7Y59

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04511	DER1	11 → 204	Der1-like family	Family

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:15215855, ECO:0000269|PubMed:16449189}.

Sequence

MSDIGDWFRSIPAITRYWFAATVAVPLVGKLGLISPAYLFLWPEAFLYRFQIWRPITATF
YFPVGPGTGFLYLVNLYFLYQYSTRLETGAFDGRPADYLFMLLFNWICIVITGLAMDMQL
LMIPLIMSVLYVWAQLNRDMIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVG
HLYFFLMFRYPMDLGGRNFLSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRH
NWGQGFRLGDQ

Sequence length

251

Interactions

View interactions

	KEGG		Reactome
	Protein processing in endoplasmic reticulum Amyotrophic lateral sclerosis Pathways of neurodegeneration - multiple diseases		ABC-family proteins mediated transport N-glycan trimming in the ER and Calnexin/Calreticulin cycle Defective CFTR causes cystic fibrosis E3 ubiquitin ligases ubiquitinate target proteins

DERL1 (derlin 1)