Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID	79096
Gene name	Centriolar satellite-associated tubulin polyglutamylase complex regulator 1
Gene symbol	CSTPP1
Synonyms (NCBI Gene)	C11orf49
Chromosome	11
Chromosome location	11p11.2

120

Show/Hide all (120)

miRTarBase ID	miRNA	Experiments
MIRT829818	hsa-miR-1225-3p	CLIP-seq
MIRT829819	hsa-miR-1269	CLIP-seq
MIRT829820	hsa-miR-1269b	CLIP-seq
MIRT829821	hsa-miR-1286	CLIP-seq
MIRT829822	hsa-miR-1296	CLIP-seq
MIRT829823	hsa-miR-1587	CLIP-seq
MIRT829824	hsa-miR-2278	CLIP-seq
MIRT829825	hsa-miR-27a	CLIP-seq
MIRT829826	hsa-miR-27b	CLIP-seq
MIRT829827	hsa-miR-3064-5p	CLIP-seq
MIRT829828	hsa-miR-3616-3p	CLIP-seq
MIRT829829	hsa-miR-3652	CLIP-seq
MIRT829830	hsa-miR-378g	CLIP-seq
MIRT829831	hsa-miR-3929	CLIP-seq
MIRT829832	hsa-miR-4252	CLIP-seq
MIRT829833	hsa-miR-4265	CLIP-seq
MIRT829834	hsa-miR-4270	CLIP-seq
MIRT829835	hsa-miR-4296	CLIP-seq
MIRT829836	hsa-miR-4322	CLIP-seq
MIRT829837	hsa-miR-4417	CLIP-seq
MIRT829838	hsa-miR-4419b	CLIP-seq
MIRT829839	hsa-miR-4430	CLIP-seq
MIRT829840	hsa-miR-4436b-3p	CLIP-seq
MIRT829841	hsa-miR-4438	CLIP-seq
MIRT829842	hsa-miR-4441	CLIP-seq
MIRT829843	hsa-miR-4478	CLIP-seq
MIRT829844	hsa-miR-4492	CLIP-seq
MIRT829845	hsa-miR-4497	CLIP-seq
MIRT829846	hsa-miR-4498	CLIP-seq
MIRT829847	hsa-miR-4505	CLIP-seq
MIRT829848	hsa-miR-4512	CLIP-seq
MIRT829849	hsa-miR-4520b-3p	CLIP-seq
MIRT829850	hsa-miR-4529-3p	CLIP-seq
MIRT829851	hsa-miR-4640-5p	CLIP-seq
MIRT829852	hsa-miR-4656	CLIP-seq
MIRT829853	hsa-miR-4670-3p	CLIP-seq
MIRT829854	hsa-miR-4675	CLIP-seq
MIRT829855	hsa-miR-4690-5p	CLIP-seq
MIRT829856	hsa-miR-4726-5p	CLIP-seq
MIRT829857	hsa-miR-4741	CLIP-seq
MIRT829858	hsa-miR-4749-3p	CLIP-seq
MIRT829859	hsa-miR-513a-5p	CLIP-seq
MIRT829860	hsa-miR-762	CLIP-seq
MIRT829861	hsa-miR-885-3p	CLIP-seq
MIRT829862	hsa-miR-892b	CLIP-seq
MIRT829821	hsa-miR-1286	CLIP-seq
MIRT829863	hsa-miR-149	CLIP-seq
MIRT829864	hsa-miR-15a	CLIP-seq
MIRT829865	hsa-miR-15b	CLIP-seq
MIRT829866	hsa-miR-16	CLIP-seq
MIRT829867	hsa-miR-195	CLIP-seq
MIRT829868	hsa-miR-214	CLIP-seq
MIRT829869	hsa-miR-24	CLIP-seq
MIRT829870	hsa-miR-2467-3p	CLIP-seq
MIRT829871	hsa-miR-3619-5p	CLIP-seq
MIRT829872	hsa-miR-424	CLIP-seq
MIRT829833	hsa-miR-4265	CLIP-seq
MIRT829873	hsa-miR-4284	CLIP-seq
MIRT829874	hsa-miR-4291	CLIP-seq
MIRT829835	hsa-miR-4296	CLIP-seq
MIRT829836	hsa-miR-4322	CLIP-seq
MIRT829837	hsa-miR-4417	CLIP-seq
MIRT829875	hsa-miR-485-5p	CLIP-seq
MIRT829876	hsa-miR-497	CLIP-seq
MIRT829877	hsa-miR-761	CLIP-seq
MIRT829878	hsa-miR-922	CLIP-seq
MIRT1945689	hsa-miR-1287	CLIP-seq
MIRT1945690	hsa-miR-1293	CLIP-seq
MIRT1945691	hsa-miR-185	CLIP-seq
MIRT1945692	hsa-miR-18a	CLIP-seq
MIRT1945693	hsa-miR-18b	CLIP-seq
MIRT1945694	hsa-miR-3135b	CLIP-seq
MIRT1945695	hsa-miR-3620	CLIP-seq
MIRT1945696	hsa-miR-4306	CLIP-seq
MIRT1945697	hsa-miR-4446-3p	CLIP-seq
MIRT1945698	hsa-miR-4483	CLIP-seq
MIRT829844	hsa-miR-4492	CLIP-seq
MIRT829846	hsa-miR-4498	CLIP-seq
MIRT829847	hsa-miR-4505	CLIP-seq
MIRT1945699	hsa-miR-4644	CLIP-seq
MIRT1945700	hsa-miR-4695-5p	CLIP-seq
MIRT1945701	hsa-miR-4735-3p	CLIP-seq
MIRT1945702	hsa-miR-4761-5p	CLIP-seq
MIRT829875	hsa-miR-485-5p	CLIP-seq
MIRT1945703	hsa-miR-541	CLIP-seq
MIRT1945704	hsa-miR-654-5p	CLIP-seq
MIRT829860	hsa-miR-762	CLIP-seq
MIRT2384959	hsa-miR-4260	CLIP-seq
MIRT2445008	hsa-miR-4698	CLIP-seq
MIRT2445009	hsa-miR-4796-3p	CLIP-seq
MIRT2445010	hsa-miR-494	CLIP-seq
MIRT2445011	hsa-miR-520g	CLIP-seq
MIRT2445012	hsa-miR-520h	CLIP-seq
MIRT829825	hsa-miR-27a	CLIP-seq
MIRT829826	hsa-miR-27b	CLIP-seq
MIRT2487686	hsa-miR-3065-3p	CLIP-seq
MIRT2384959	hsa-miR-4260	CLIP-seq
MIRT829841	hsa-miR-4438	CLIP-seq
MIRT2487687	hsa-miR-4453	CLIP-seq
MIRT2487688	hsa-miR-4504	CLIP-seq
MIRT2487689	hsa-miR-4538	CLIP-seq
MIRT2487690	hsa-miR-4757-5p	CLIP-seq
MIRT1945702	hsa-miR-4761-5p	CLIP-seq
MIRT829859	hsa-miR-513a-5p	CLIP-seq
MIRT2487691	hsa-miR-622	CLIP-seq
MIRT2487692	hsa-miR-624	CLIP-seq
MIRT829825	hsa-miR-27a	CLIP-seq
MIRT829826	hsa-miR-27b	CLIP-seq
MIRT2487686	hsa-miR-3065-3p	CLIP-seq
MIRT2384959	hsa-miR-4260	CLIP-seq
MIRT829841	hsa-miR-4438	CLIP-seq
MIRT2487687	hsa-miR-4453	CLIP-seq
MIRT2487688	hsa-miR-4504	CLIP-seq
MIRT2487689	hsa-miR-4538	CLIP-seq
MIRT829853	hsa-miR-4670-3p	CLIP-seq
MIRT2487690	hsa-miR-4757-5p	CLIP-seq
MIRT1945702	hsa-miR-4761-5p	CLIP-seq
MIRT829859	hsa-miR-513a-5p	CLIP-seq
MIRT2487691	hsa-miR-622	CLIP-seq
MIRT2487692	hsa-miR-624	CLIP-seq

Show/Hide all (12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000226	Process	Microtubule cytoskeleton organization	IDA	34782749
GO:0005515	Function	Protein binding	IPI	25416956, 32296183, 32814053
GO:0005737	Component	Cytoplasm	IEA
GO:0005856	Component	Cytoskeleton	IEA
GO:0005874	Component	Microtubule	IEA
GO:0030674	Function	Protein-macromolecule adaptor activity	IDA	34782749
GO:0034451	Component	Centriolar satellite	IDA	34782749
GO:0034451	Component	Centriolar satellite	IDA	26638075
GO:0034451	Component	Centriolar satellite	IEA
GO:0046785	Process	Microtubule polymerization	IDA	10791892, 34782749
GO:0061523	Process	Cilium disassembly	IDA	34782749
GO:0061635	Process	Regulation of protein complex stability	IDA	34782749

MIM	HGNC	e!Ensembl
620479	28720	ENSG00000149179

Q9H6J7

Protein name

Centriolar satellite-associated tubulin polyglutamylase complex regulator 1

Protein function

Regulator of the tubulin polyglutamylase complex (TPGC) that controls cytoskeletal organization, nuclear shape, and cilium disassembly by balancing microtubule and actin assembly (PubMed:34782749). Regulates the assembly and stability of the TPG

Family and domains

Sequence

MLSPERLALPDYEYLAQRHVLTYMEDAVCQLLENREDISQYGIARFFTEYFNSVCQGTHI
LFREFSFVQATPHNRVSFLRAFWRCFRTVGKNGDLLTMKEYHCLLQLLCPDFPLELTQKA
ARIVLMDDAMDCLMSFSDFLFAFQIQFYYSEFLDSVAAIYEDLLSGKNPNTVIVPTSSSG
QHRQRPALGGAGTLEGVEASLFYQCLENLCDRHKYSCPPPALVKEALSNVQRLTFYGFLM
ALSKHRGINQALGALPDKGDLMHDPAMDEELERLLAQVPGLVNSVTASPEASCLPSRTPP
RVGSPWRPLHHSRKVDGESDGSTEETDESET

Sequence length

331

Interactions

View interactions

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (7)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
MOOD DISORDER	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
PERIPHERAL VASCULAR DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
TYPE 2 DIABETES MELLITUS	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VASCULAR DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
VENOUS THROMBOEMBOLISM	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

CSTPP1 (centriolar satellite-associated tubulin polyglutamylase complex regulator 1)