Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	790955
Gene name Gene Name - the full gene name approved by the HGNC.	Ubiquinol-cytochrome c reductase complex assembly factor 3
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	UQCC3
Synonyms (NCBI Gene) Gene synonyms aliases	C11orf83, CCDS41658.1, MC3DN9, UNQ655
Disease Acronyms (UniProt) Disease acronyms from UniProt database	MC3DN9
Chromosome Chromosome number	11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	11q12.3
Summary Summary of gene provided in NCBI Entrez Gene.	Complex III is a mitochondrial inner membrane protein complex that transfers electrons from ubiquinol to cytochrome c. This gene encodes a protein that functions in complex III assembly. Mutations in this gene result in Mitochondrial complex III deficienc

Show/Hide all(206)

miRTarBase ID	miRNA	Experiments	Reference
MIRT753910	hsa-miR-1287-5p	PAR-CLIP	26701625
MIRT753902	hsa-miR-1915-3p	PAR-CLIP	26701625
MIRT753911	hsa-miR-25-5p	PAR-CLIP	26701625
MIRT755162	hsa-miR-302f	PAR-CLIP	26701625
MIRT753909	hsa-miR-3135b	PAR-CLIP	26701625
MIRT753913	hsa-miR-3180-3p	PAR-CLIP	26701625
MIRT753912	hsa-miR-3180	PAR-CLIP	26701625
MIRT753914	hsa-miR-3196	PAR-CLIP	26701625
MIRT753905	hsa-miR-377-5p	PAR-CLIP	26701625
MIRT753904	hsa-miR-4537	PAR-CLIP	26701625
MIRT753916	hsa-miR-455-3p	PAR-CLIP	26701625
MIRT753906	hsa-miR-6086	PAR-CLIP	26701625
MIRT753907	hsa-miR-6499-3p	PAR-CLIP	26701625
MIRT753917	hsa-miR-6516-5p	PAR-CLIP	26701625
MIRT753908	hsa-miR-658	PAR-CLIP	26701625
MIRT753903	hsa-miR-6764-5p	PAR-CLIP	26701625
MIRT753915	hsa-miR-6816-5p	PAR-CLIP	26701625
MIRT753910	hsa-miR-1287-5p	PAR-CLIP	27292025
MIRT753910	hsa-miR-1287-5p	PAR-CLIP	27292025
MIRT753902	hsa-miR-1915-3p	PAR-CLIP	27292025
MIRT753902	hsa-miR-1915-3p	PAR-CLIP	27292025
MIRT753911	hsa-miR-25-5p	PAR-CLIP	27292025
MIRT753911	hsa-miR-25-5p	PAR-CLIP	27292025
MIRT753909	hsa-miR-3135b	PAR-CLIP	27292025
MIRT753909	hsa-miR-3135b	PAR-CLIP	27292025
MIRT753913	hsa-miR-3180-3p	PAR-CLIP	27292025
MIRT753913	hsa-miR-3180-3p	PAR-CLIP	27292025
MIRT753912	hsa-miR-3180	PAR-CLIP	27292025
MIRT753912	hsa-miR-3180	PAR-CLIP	27292025
MIRT753914	hsa-miR-3196	PAR-CLIP	27292025
MIRT753914	hsa-miR-3196	PAR-CLIP	27292025
MIRT753905	hsa-miR-377-5p	PAR-CLIP	27292025
MIRT753905	hsa-miR-377-5p	PAR-CLIP	27292025
MIRT753904	hsa-miR-4537	PAR-CLIP	27292025
MIRT753904	hsa-miR-4537	PAR-CLIP	27292025
MIRT753916	hsa-miR-455-3p	PAR-CLIP	27292025
MIRT753916	hsa-miR-455-3p	PAR-CLIP	27292025
MIRT753906	hsa-miR-6086	PAR-CLIP	27292025
MIRT753906	hsa-miR-6086	PAR-CLIP	27292025
MIRT753907	hsa-miR-6499-3p	PAR-CLIP	27292025
MIRT753907	hsa-miR-6499-3p	PAR-CLIP	27292025
MIRT753917	hsa-miR-6516-5p	PAR-CLIP	27292025
MIRT753917	hsa-miR-6516-5p	PAR-CLIP	27292025
MIRT753908	hsa-miR-658	PAR-CLIP	27292025
MIRT753908	hsa-miR-658	PAR-CLIP	27292025
MIRT753903	hsa-miR-6764-5p	PAR-CLIP	27292025
MIRT753903	hsa-miR-6764-5p	PAR-CLIP	27292025
MIRT753915	hsa-miR-6816-5p	PAR-CLIP	27292025
MIRT753915	hsa-miR-6816-5p	PAR-CLIP	27292025
MIRT741811	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT741812	hsa-miR-1273g-3p	HITS-CLIP	23824327
MIRT741813	hsa-miR-6849-3p	HITS-CLIP	23824327
MIRT741814	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT741815	hsa-miR-766-3p	HITS-CLIP	23824327
MIRT741816	hsa-miR-4793-3p	HITS-CLIP	23824327
MIRT741817	hsa-miR-6776-5p	HITS-CLIP	23824327
MIRT741818	hsa-miR-4252	HITS-CLIP	23824327
MIRT741819	hsa-miR-661	HITS-CLIP	23824327
MIRT741820	hsa-miR-1227-3p	HITS-CLIP	23824327
MIRT741821	hsa-miR-6512-3p	HITS-CLIP	23824327
MIRT741822	hsa-miR-6720-5p	HITS-CLIP	23824327
MIRT741823	hsa-miR-7703	HITS-CLIP	23824327
MIRT741824	hsa-miR-1262	HITS-CLIP	23824327
MIRT741825	hsa-miR-4701-3p	HITS-CLIP	23824327
MIRT741826	hsa-miR-6736-5p	HITS-CLIP	23824327
MIRT741827	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT741828	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT741829	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT741830	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT741831	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT741832	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT741833	hsa-miR-3122	HITS-CLIP	23824327
MIRT741834	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT741835	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT741836	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT741837	hsa-miR-5693	HITS-CLIP	23824327
MIRT741838	hsa-miR-6499-5p	HITS-CLIP	23824327
MIRT741839	hsa-miR-4743-5p	HITS-CLIP	23824327
MIRT741840	hsa-miR-4284	HITS-CLIP	23824327
MIRT741841	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT741827	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT741828	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT741829	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT741830	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT741831	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT741832	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT741833	hsa-miR-3122	HITS-CLIP	23824327
MIRT741834	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT741835	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT741836	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT741827	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT741828	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT741829	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT741830	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT741831	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT741832	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT741833	hsa-miR-3122	HITS-CLIP	23824327
MIRT741834	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT741835	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT741836	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT741827	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT741828	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT742359	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT742360	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT742361	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT742362	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT742363	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT742364	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT742365	hsa-miR-7977	HITS-CLIP	23824327
MIRT741829	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT741830	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT741831	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT742366	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT742367	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT742368	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT742369	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT742370	hsa-miR-3689c	HITS-CLIP	23824327
MIRT742371	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT742372	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT741832	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT741833	hsa-miR-3122	HITS-CLIP	23824327
MIRT741834	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT741835	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT741836	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT741827	hsa-miR-129-1-3p	HITS-CLIP	23824327
MIRT741828	hsa-miR-129-2-3p	HITS-CLIP	23824327
MIRT742359	hsa-miR-7106-5p	HITS-CLIP	23824327
MIRT742360	hsa-miR-149-3p	HITS-CLIP	23824327
MIRT742361	hsa-miR-4728-5p	HITS-CLIP	23824327
MIRT742362	hsa-miR-6785-5p	HITS-CLIP	23824327
MIRT742363	hsa-miR-6883-5p	HITS-CLIP	23824327
MIRT742364	hsa-miR-6799-5p	HITS-CLIP	23824327
MIRT741829	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT741830	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT741831	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT742366	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT742367	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT742368	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT742369	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT742370	hsa-miR-3689c	HITS-CLIP	23824327
MIRT742371	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT742372	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT741832	hsa-miR-450a-1-3p	HITS-CLIP	23824327
MIRT741833	hsa-miR-3122	HITS-CLIP	23824327
MIRT741834	hsa-miR-3913-5p	HITS-CLIP	23824327
MIRT741835	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT741836	hsa-miR-6513-5p	HITS-CLIP	23824327
MIRT753902	hsa-miR-1915-3p	PAR-CLIP	20371350
MIRT753903	hsa-miR-6764-5p	PAR-CLIP	20371350
MIRT753904	hsa-miR-4537	PAR-CLIP	20371350
MIRT753905	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT753906	hsa-miR-6086	PAR-CLIP	20371350
MIRT753907	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT753908	hsa-miR-658	PAR-CLIP	20371350
MIRT753909	hsa-miR-3135b	PAR-CLIP	20371350
MIRT753910	hsa-miR-1287-5p	PAR-CLIP	20371350
MIRT753911	hsa-miR-25-5p	PAR-CLIP	20371350
MIRT753912	hsa-miR-3180	PAR-CLIP	20371350
MIRT753913	hsa-miR-3180-3p	PAR-CLIP	20371350
MIRT753914	hsa-miR-3196	PAR-CLIP	20371350
MIRT753915	hsa-miR-6816-5p	PAR-CLIP	20371350
MIRT753916	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT753917	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT753902	hsa-miR-1915-3p	PAR-CLIP	20371350
MIRT753903	hsa-miR-6764-5p	PAR-CLIP	20371350
MIRT753904	hsa-miR-4537	PAR-CLIP	20371350
MIRT753905	hsa-miR-377-5p	PAR-CLIP	20371350
MIRT753906	hsa-miR-6086	PAR-CLIP	20371350
MIRT753907	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT753908	hsa-miR-658	PAR-CLIP	20371350
MIRT753909	hsa-miR-3135b	PAR-CLIP	20371350
MIRT753910	hsa-miR-1287-5p	PAR-CLIP	20371350
MIRT753911	hsa-miR-25-5p	PAR-CLIP	20371350
MIRT753912	hsa-miR-3180	PAR-CLIP	20371350
MIRT753913	hsa-miR-3180-3p	PAR-CLIP	20371350
MIRT753914	hsa-miR-3196	PAR-CLIP	20371350
MIRT753915	hsa-miR-6816-5p	PAR-CLIP	20371350
MIRT753916	hsa-miR-455-3p	PAR-CLIP	20371350
MIRT753917	hsa-miR-6516-5p	PAR-CLIP	20371350
MIRT754800	hsa-miR-3929	PAR-CLIP	22291592
MIRT754801	hsa-miR-4419b	PAR-CLIP	22291592
MIRT754802	hsa-miR-4478	PAR-CLIP	22291592
MIRT754803	hsa-miR-645	PAR-CLIP	22291592
MIRT754804	hsa-miR-134-3p	PAR-CLIP	22291592
MIRT754805	hsa-miR-891b	PAR-CLIP	22291592
MIRT754806	hsa-miR-7974	PAR-CLIP	22291592
MIRT754807	hsa-miR-380-5p	PAR-CLIP	22291592
MIRT754808	hsa-miR-563	PAR-CLIP	22291592
MIRT755162	hsa-miR-302f	PAR-CLIP	23592263
MIRT753902	hsa-miR-1915-3p	PAR-CLIP	23592263
MIRT753903	hsa-miR-6764-5p	PAR-CLIP	23592263
MIRT755163	hsa-miR-219b-3p	PAR-CLIP	23592263
MIRT753904	hsa-miR-4537	PAR-CLIP	23592263
MIRT753905	hsa-miR-377-5p	PAR-CLIP	23592263
MIRT753906	hsa-miR-6086	PAR-CLIP	23592263
MIRT753907	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT753908	hsa-miR-658	PAR-CLIP	23592263
MIRT753909	hsa-miR-3135b	PAR-CLIP	23592263
MIRT753910	hsa-miR-1287-5p	PAR-CLIP	23592263
MIRT753911	hsa-miR-25-5p	PAR-CLIP	23592263
MIRT753912	hsa-miR-3180	PAR-CLIP	23592263
MIRT753913	hsa-miR-3180-3p	PAR-CLIP	23592263
MIRT753914	hsa-miR-3196	PAR-CLIP	23592263
MIRT753915	hsa-miR-6816-5p	PAR-CLIP	23592263
MIRT753916	hsa-miR-455-3p	PAR-CLIP	23592263
MIRT753917	hsa-miR-6516-5p	PAR-CLIP	23592263

Show/Hide all(15)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005654	Component	Nucleoplasm	IDA
GO:0005739	Component	Mitochondrion	IDA
GO:0005750	Component	Mitochondrial respiratory chain complex III	IBA	21873635
GO:0005750	Component	Mitochondrial respiratory chain complex III	IDA	25605331
GO:0005829	Component	Cytosol	IDA
GO:0006122	Process	Mitochondrial electron transport, ubiquinol to cytochrome c	IBA	21873635
GO:0006122	Process	Mitochondrial electron transport, ubiquinol to cytochrome c	IMP	25008109
GO:0006754	Process	ATP biosynthetic process	IEA
GO:0031305	Component	Integral component of mitochondrial inner membrane	IBA	21873635
GO:0031305	Component	Integral component of mitochondrial inner membrane	IDA	25008109, 25605331
GO:0034551	Process	Mitochondrial respiratory chain complex III assembly	IBA	21873635
GO:0034551	Process	Mitochondrial respiratory chain complex III assembly	IMP	25605331
GO:0042407	Process	Cristae formation	IMP	25605331
GO:0070300	Function	Phosphatidic acid binding	IDA	25605331
GO:1901612	Function	Cardiolipin binding	IDA	25605331

MIM	HGNC	e!Ensembl
616097	34399	ENSG00000204922

Protein

UniProt ID

Q6UW78

Protein name

Ubiquinol-cytochrome-c reductase complex assembly factor 3 (Assembly factor CBP4 homolog)

Protein function

Required for the assembly of the ubiquinol-cytochrome c reductase complex (mitochondrial respiratory chain complex III or cytochrome b-c1 complex), mediating cytochrome b recruitment and probably stabilization within the complex. Thereby, plays

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF15141	UQCC3	1 → 91	Ubiquinol-cytochrome-c reductase complex assembly factor 3	Family

Sequence

MDSLRKMLISVAMLGAGAGVGYALLVIVTPGERRKQEMLKEMPLQDPRSREEAARTQQLL
LATLQEAATTQENVAWRKNWMVGGEGGAGGRSP

Sequence length

Interactions

View interactions

Show/Hide Causal Diseases (2)

Disease term	Disease name	dbSNP ID	References
Causal
Developmental delay	Global developmental delay	rs28941770, rs199469464, rs281865469, rs143747297, rs398123009, rs587777428, rs786205133, rs606231459, rs797044854, rs797045027, rs864309504, rs878853160, rs886039902, rs886042046, rs886041291 View all (32 more)
Mitochondrial complex deficiency	MITOCHONDRIAL COMPLEX III DEFICIENCY, NUCLEAR TYPE 9, MITOCHONDRIAL COMPLEX III DEFICIENCY (disorder)	rs267606829, rs267606830, rs587776513, rs121918134, rs121918135, rs121918136, rs137853192, rs137853193, rs183973249, rs137853184, rs118203929, rs267606689, rs11544803, rs63751061, rs137852863 View all (210 more)	25008109, 28804536

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Mitochondrial Complex Deficiency	mitochondrial complex III deficiency			GenCC

UQCC3 (ubiquinol-cytochrome c reductase complex assembly factor 3)