Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	79090
Gene name Gene Name - the full gene name approved by the HGNC.	Trafficking protein particle complex subunit 6A
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TRAPPC6A
Synonyms (NCBI Gene) Gene synonyms aliases	TRS33
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19q13.32
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a component of the trafficking protein particle complex, which tethers transport vesicles to the cis-Golgi membrane. Loss of expression of the related gene in mouse affects coat and eye pigmentation, suggesting that the encoded protein m

Show/Hide all(72)

miRTarBase ID	miRNA	Experiments	Reference
MIRT030324	hsa-miR-26b-5p	Microarray	19088304
MIRT617112	hsa-miR-8485	HITS-CLIP	23824327
MIRT617111	hsa-miR-4461	HITS-CLIP	23824327
MIRT617109	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT617112	hsa-miR-8485	HITS-CLIP	23824327
MIRT617111	hsa-miR-4461	HITS-CLIP	23824327
MIRT617110	hsa-miR-10b-3p	HITS-CLIP	23824327
MIRT617109	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT617112	hsa-miR-8485	HITS-CLIP	23824327
MIRT617111	hsa-miR-4461	HITS-CLIP	23824327
MIRT617109	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT617112	hsa-miR-8485	HITS-CLIP	23824327
MIRT617111	hsa-miR-4461	HITS-CLIP	23824327
MIRT617110	hsa-miR-10b-3p	HITS-CLIP	23824327
MIRT617109	hsa-miR-3692-3p	HITS-CLIP	23824327
MIRT2135375	hsa-miR-1224-3p	CLIP-seq
MIRT2135376	hsa-miR-1260	CLIP-seq
MIRT2135377	hsa-miR-1260b	CLIP-seq
MIRT2135378	hsa-miR-1280	CLIP-seq
MIRT2135379	hsa-miR-140-3p	CLIP-seq
MIRT2135380	hsa-miR-3692	CLIP-seq
MIRT2356413	hsa-miR-214	CLIP-seq
MIRT2356414	hsa-miR-24	CLIP-seq
MIRT2356415	hsa-miR-3619-5p	CLIP-seq
MIRT2356416	hsa-miR-3665	CLIP-seq
MIRT2356417	hsa-miR-4291	CLIP-seq
MIRT2356418	hsa-miR-4316	CLIP-seq
MIRT2356419	hsa-miR-4519	CLIP-seq
MIRT2356420	hsa-miR-4688	CLIP-seq
MIRT2356421	hsa-miR-4710	CLIP-seq
MIRT2356422	hsa-miR-486-3p	CLIP-seq
MIRT2356423	hsa-miR-761	CLIP-seq
MIRT2356424	hsa-miR-764	CLIP-seq
MIRT2356425	hsa-miR-922	CLIP-seq
MIRT2650031	hsa-miR-1200	CLIP-seq
MIRT2650032	hsa-miR-1207-3p	CLIP-seq
MIRT2135375	hsa-miR-1224-3p	CLIP-seq
MIRT2135376	hsa-miR-1260	CLIP-seq
MIRT2135377	hsa-miR-1260b	CLIP-seq
MIRT2135378	hsa-miR-1280	CLIP-seq
MIRT2650033	hsa-miR-1296	CLIP-seq
MIRT2135379	hsa-miR-140-3p	CLIP-seq
MIRT2650034	hsa-miR-1910	CLIP-seq
MIRT2650035	hsa-miR-1976	CLIP-seq
MIRT2356413	hsa-miR-214	CLIP-seq
MIRT2356414	hsa-miR-24	CLIP-seq
MIRT2650036	hsa-miR-2861	CLIP-seq
MIRT2356415	hsa-miR-3619-5p	CLIP-seq
MIRT2356417	hsa-miR-4291	CLIP-seq
MIRT2356418	hsa-miR-4316	CLIP-seq
MIRT2650037	hsa-miR-4324	CLIP-seq
MIRT2650038	hsa-miR-4501	CLIP-seq
MIRT2650039	hsa-miR-4512	CLIP-seq
MIRT2356419	hsa-miR-4519	CLIP-seq
MIRT2650040	hsa-miR-4649-3p	CLIP-seq
MIRT2356420	hsa-miR-4688	CLIP-seq
MIRT2356421	hsa-miR-4710	CLIP-seq
MIRT2650041	hsa-miR-4758-3p	CLIP-seq
MIRT2356422	hsa-miR-486-3p	CLIP-seq
MIRT2650042	hsa-miR-544b	CLIP-seq
MIRT2650043	hsa-miR-661	CLIP-seq
MIRT2356423	hsa-miR-761	CLIP-seq
MIRT2356425	hsa-miR-922	CLIP-seq
MIRT2650031	hsa-miR-1200	CLIP-seq
MIRT2135375	hsa-miR-1224-3p	CLIP-seq
MIRT2650033	hsa-miR-1296	CLIP-seq
MIRT2650036	hsa-miR-2861	CLIP-seq
MIRT2650037	hsa-miR-4324	CLIP-seq
MIRT2650038	hsa-miR-4501	CLIP-seq
MIRT2650039	hsa-miR-4512	CLIP-seq
MIRT2650042	hsa-miR-544b	CLIP-seq
MIRT2650043	hsa-miR-661	CLIP-seq

Show/Hide all(11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000139	Component	Golgi membrane	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 16828797, 18930054, 21273506, 23088713, 25416956, 31515488
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005801	Component	Cis-Golgi network	IBA	21873635
GO:0005802	Component	Trans-Golgi network	IBA	21873635
GO:0005829	Component	Cytosol	TAS
GO:0006888	Process	Endoplasmic reticulum to Golgi vesicle-mediated transport	IBA	21873635
GO:0030008	Component	TRAPP complex	IBA	21873635
GO:0043087	Process	Regulation of GTPase activity	IEA
GO:0048208	Process	COPII vesicle coating	TAS
GO:1903232	Process	Melanosome assembly	IBA	21873635

MIM	HGNC	e!Ensembl
610396	23069	ENSG00000007255

Protein

UniProt ID

O75865

Protein name

Trafficking protein particle complex subunit 6A (TRAPP complex subunit 6A)

Protein function

May play a role in vesicular transport during the biogenesis of melanosomes.

PDB

2C0J , 2J3T

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF04051	TRAPP	7 → 157	Transport protein particle (TRAPP) component	Family

Sequence

MADTVLFEFLHTEMVAELWAHDPDPGPGGQKMSLSVLEGMGFRVGQALGERLPRETLAFR
EELDVLKFLCKDLWVAVFQKQMDSLRTNHQGTYVLQDNSFPLLLPMASGLQYLEEAPKFL
AFTCGLLRGALYTLGIESVVTASVAALPVCKFQVVIPKS

Sequence length

159

Interactions

View interactions

	Reactome
			COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Mental retardation	Intellectual Disability	rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315 View all (1024 more)	29391579

Show/Hide Unknown Diseases (2)

Disease term	Disease name	Source
Unknown
Neurodevelopmental Disorders	complex neurodevelopmental disorder	GenCC
Alzheimer disease	Alzheimer disease	GWAS

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text Mining
Congenital Abnormalities	Associate	29391579
Fetal Alcohol Spectrum Disorders	Associate	29391579
Intellectual Disability	Associate	29391579

TRAPPC6A (trafficking protein particle complex subunit 6A)