CCDC86 (coiled-coil domain containing 86)

Gene

• Entrez ID: 79080
• Gene name: Coiled-coil domain containing 86
• Gene symbol: CCDC86
• Synonyms (NCBI Gene): Cgr1
• Chromosome: 11
• Chromosome location: 11q12.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT022797	hsa-miR-124-3p	Proteomics;Microarray	18668037
MIRT049209	hsa-miR-92a-3p	CLASH	23622248
MIRT504903	hsa-miR-1226-3p	PAR-CLIP	23446348
MIRT504902	hsa-miR-4733-3p	PAR-CLIP	23446348
MIRT504901	hsa-miR-3622a-3p	PAR-CLIP	23446348
MIRT504900	hsa-miR-3622b-3p	PAR-CLIP	23446348
MIRT504898	hsa-miR-6765-3p	PAR-CLIP	23446348
MIRT504899	hsa-miR-4704-3p	PAR-CLIP	23446348
MIRT504897	hsa-miR-4267	PAR-CLIP	23446348
MIRT504896	hsa-miR-4722-3p	PAR-CLIP	23446348
MIRT504895	hsa-miR-6727-3p	PAR-CLIP	23446348
MIRT504903	hsa-miR-1226-3p	PAR-CLIP	23446348
MIRT504902	hsa-miR-4733-3p	PAR-CLIP	23446348
MIRT504901	hsa-miR-3622a-3p	PAR-CLIP	23446348
MIRT504900	hsa-miR-3622b-3p	PAR-CLIP	23446348
MIRT504898	hsa-miR-6765-3p	PAR-CLIP	23446348
MIRT504899	hsa-miR-4704-3p	PAR-CLIP	23446348
MIRT504897	hsa-miR-4267	PAR-CLIP	23446348
MIRT504896	hsa-miR-4722-3p	PAR-CLIP	23446348
MIRT504895	hsa-miR-6727-3p	PAR-CLIP	23446348
MIRT479850	hsa-miR-548az-5p	PAR-CLIP	23592263
MIRT479848	hsa-miR-548t-5p	PAR-CLIP	23592263
MIRT479847	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT479845	hsa-miR-3125	PAR-CLIP	23592263
MIRT479846	hsa-miR-3916	PAR-CLIP	23592263
MIRT479844	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT479843	hsa-miR-3914	PAR-CLIP	23592263
MIRT479842	hsa-miR-16-1-3p	PAR-CLIP	23592263
MIRT479841	hsa-miR-622	PAR-CLIP	23592263
MIRT479840	hsa-miR-93-3p	PAR-CLIP	23592263
MIRT479839	hsa-miR-3692-5p	PAR-CLIP	23592263
MIRT479838	hsa-miR-3928-3p	PAR-CLIP	23592263
MIRT479837	hsa-miR-4731-5p	PAR-CLIP	23592263
MIRT479836	hsa-miR-5589-5p	PAR-CLIP	23592263
MIRT479835	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT479834	hsa-miR-4306	PAR-CLIP	23592263
MIRT479833	hsa-miR-4644	PAR-CLIP	23592263
MIRT479832	hsa-miR-5192	PAR-CLIP	23592263
MIRT479831	hsa-miR-222-5p	PAR-CLIP	23592263
MIRT479830	hsa-miR-6071	PAR-CLIP	23592263
MIRT479829	hsa-miR-30a-3p	PAR-CLIP	23592263
MIRT479828	hsa-miR-30d-3p	PAR-CLIP	23592263
MIRT479827	hsa-miR-30e-3p	PAR-CLIP	23592263
MIRT504903	hsa-miR-1226-3p	PAR-CLIP	26701625
MIRT504901	hsa-miR-3622a-3p	PAR-CLIP	26701625
MIRT504900	hsa-miR-3622b-3p	PAR-CLIP	26701625
MIRT504897	hsa-miR-4267	PAR-CLIP	26701625
MIRT504899	hsa-miR-4704-3p	PAR-CLIP	26701625
MIRT504896	hsa-miR-4722-3p	PAR-CLIP	26701625
MIRT504902	hsa-miR-4733-3p	PAR-CLIP	26701625
MIRT504895	hsa-miR-6727-3p	PAR-CLIP	26701625
MIRT504898	hsa-miR-6765-3p	PAR-CLIP	26701625
MIRT504903	hsa-miR-1226-3p	PAR-CLIP	23446348
MIRT504902	hsa-miR-4733-3p	PAR-CLIP	23446348
MIRT504901	hsa-miR-3622a-3p	PAR-CLIP	23446348
MIRT504900	hsa-miR-3622b-3p	PAR-CLIP	23446348
MIRT504898	hsa-miR-6765-3p	PAR-CLIP	23446348
MIRT504899	hsa-miR-4704-3p	PAR-CLIP	23446348
MIRT504897	hsa-miR-4267	PAR-CLIP	23446348
MIRT504896	hsa-miR-4722-3p	PAR-CLIP	23446348
MIRT504895	hsa-miR-6727-3p	PAR-CLIP	23446348
MIRT504903	hsa-miR-1226-3p	PAR-CLIP	23446348
MIRT504902	hsa-miR-4733-3p	PAR-CLIP	23446348
MIRT504901	hsa-miR-3622a-3p	PAR-CLIP	23446348
MIRT504900	hsa-miR-3622b-3p	PAR-CLIP	23446348
MIRT504898	hsa-miR-6765-3p	PAR-CLIP	23446348
MIRT504899	hsa-miR-4704-3p	PAR-CLIP	23446348
MIRT504897	hsa-miR-4267	PAR-CLIP	23446348
MIRT504896	hsa-miR-4722-3p	PAR-CLIP	23446348
MIRT504895	hsa-miR-6727-3p	PAR-CLIP	23446348
MIRT479850	hsa-miR-548az-5p	PAR-CLIP	23592263
MIRT479848	hsa-miR-548t-5p	PAR-CLIP	23592263
MIRT479847	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT479845	hsa-miR-3125	PAR-CLIP	23592263
MIRT479846	hsa-miR-3916	PAR-CLIP	23592263
MIRT479844	hsa-miR-6859-5p	PAR-CLIP	23592263
MIRT479843	hsa-miR-3914	PAR-CLIP	23592263
MIRT479842	hsa-miR-16-1-3p	PAR-CLIP	23592263
MIRT479841	hsa-miR-622	PAR-CLIP	23592263
MIRT479840	hsa-miR-93-3p	PAR-CLIP	23592263
MIRT479839	hsa-miR-3692-5p	PAR-CLIP	23592263
MIRT479838	hsa-miR-3928-3p	PAR-CLIP	23592263
MIRT479837	hsa-miR-4731-5p	PAR-CLIP	23592263
MIRT479836	hsa-miR-5589-5p	PAR-CLIP	23592263
MIRT479835	hsa-miR-185-5p	PAR-CLIP	23592263
MIRT479834	hsa-miR-4306	PAR-CLIP	23592263
MIRT479833	hsa-miR-4644	PAR-CLIP	23592263
MIRT479832	hsa-miR-5192	PAR-CLIP	23592263
MIRT479831	hsa-miR-222-5p	PAR-CLIP	23592263
MIRT479830	hsa-miR-6071	PAR-CLIP	23592263
MIRT479829	hsa-miR-30a-3p	PAR-CLIP	23592263
MIRT479828	hsa-miR-30d-3p	PAR-CLIP	23592263
MIRT479827	hsa-miR-30e-3p	PAR-CLIP	23592263
MIRT870071	hsa-miR-1207-5p	CLIP-seq
MIRT870072	hsa-miR-1231	CLIP-seq
MIRT870073	hsa-miR-133a	CLIP-seq
MIRT870074	hsa-miR-133b	CLIP-seq
MIRT870075	hsa-miR-136	CLIP-seq
MIRT870076	hsa-miR-1827	CLIP-seq
MIRT870077	hsa-miR-2682	CLIP-seq
MIRT870078	hsa-miR-3144-5p	CLIP-seq
MIRT870079	hsa-miR-3191	CLIP-seq
MIRT870080	hsa-miR-34a	CLIP-seq
MIRT870081	hsa-miR-34c-5p	CLIP-seq
MIRT870082	hsa-miR-3616-3p	CLIP-seq
MIRT870083	hsa-miR-3945	CLIP-seq
MIRT870084	hsa-miR-4251	CLIP-seq
MIRT870085	hsa-miR-4268	CLIP-seq
MIRT870086	hsa-miR-4288	CLIP-seq
MIRT870087	hsa-miR-4307	CLIP-seq
MIRT870088	hsa-miR-4436b-3p	CLIP-seq
MIRT870089	hsa-miR-449a	CLIP-seq
MIRT870090	hsa-miR-449b	CLIP-seq
MIRT870091	hsa-miR-449c	CLIP-seq
MIRT870092	hsa-miR-4652-5p	CLIP-seq
MIRT870093	hsa-miR-4663	CLIP-seq
MIRT870094	hsa-miR-4667-5p	CLIP-seq
MIRT870095	hsa-miR-4700-5p	CLIP-seq
MIRT870096	hsa-miR-4728-3p	CLIP-seq
MIRT870097	hsa-miR-4742-3p	CLIP-seq
MIRT870098	hsa-miR-4761-3p	CLIP-seq
MIRT870099	hsa-miR-4763-3p	CLIP-seq
MIRT870100	hsa-miR-4768-5p	CLIP-seq
MIRT870101	hsa-miR-4795-3p	CLIP-seq
MIRT870102	hsa-miR-539	CLIP-seq
MIRT870103	hsa-miR-601	CLIP-seq
MIRT870104	hsa-miR-632	CLIP-seq
MIRT870105	hsa-miR-9	CLIP-seq
MIRT870071	hsa-miR-1207-5p	CLIP-seq
MIRT1958322	hsa-miR-1236	CLIP-seq
MIRT1958323	hsa-miR-129-5p	CLIP-seq
MIRT1958324	hsa-miR-151-3p	CLIP-seq
MIRT1958325	hsa-miR-1915	CLIP-seq
MIRT1958326	hsa-miR-216b	CLIP-seq
MIRT1958327	hsa-miR-3160-3p	CLIP-seq
MIRT1958328	hsa-miR-3194-3p	CLIP-seq
MIRT870082	hsa-miR-3616-3p	CLIP-seq
MIRT1958329	hsa-miR-4258	CLIP-seq
MIRT870085	hsa-miR-4268	CLIP-seq
MIRT1958330	hsa-miR-4300	CLIP-seq
MIRT870088	hsa-miR-4436b-3p	CLIP-seq
MIRT1958331	hsa-miR-4463	CLIP-seq
MIRT1958332	hsa-miR-4499	CLIP-seq
MIRT870094	hsa-miR-4667-5p	CLIP-seq
MIRT870095	hsa-miR-4700-5p	CLIP-seq
MIRT1958333	hsa-miR-4718	CLIP-seq
MIRT1958334	hsa-miR-4726-3p	CLIP-seq
MIRT1958335	hsa-miR-4727-5p	CLIP-seq
MIRT1958336	hsa-miR-4755-3p	CLIP-seq
MIRT870099	hsa-miR-4763-3p	CLIP-seq
MIRT1958337	hsa-miR-4769-3p	CLIP-seq
MIRT1958338	hsa-miR-4772-3p	CLIP-seq
MIRT1958339	hsa-miR-767-3p	CLIP-seq
MIRT1958340	hsa-miR-920	CLIP-seq
MIRT870071	hsa-miR-1207-5p	CLIP-seq
MIRT2195101	hsa-miR-1226	CLIP-seq
MIRT870073	hsa-miR-133a	CLIP-seq
MIRT870074	hsa-miR-133b	CLIP-seq
MIRT870075	hsa-miR-136	CLIP-seq
MIRT870082	hsa-miR-3616-3p	CLIP-seq
MIRT2195102	hsa-miR-3915	CLIP-seq
MIRT2195103	hsa-miR-3928	CLIP-seq
MIRT870085	hsa-miR-4268	CLIP-seq
MIRT2195104	hsa-miR-4420	CLIP-seq
MIRT870088	hsa-miR-4436b-3p	CLIP-seq
MIRT870093	hsa-miR-4663	CLIP-seq
MIRT870098	hsa-miR-4761-3p	CLIP-seq
MIRT870099	hsa-miR-4763-3p	CLIP-seq
MIRT870105	hsa-miR-9	CLIP-seq
MIRT870094	hsa-miR-4667-5p	CLIP-seq
MIRT870095	hsa-miR-4700-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0005515	Function	Protein binding	IPI	15607035
GO:0005634	Component	Nucleus	IDA	17300783
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005694	Component	Chromosome	IDA	36695333
GO:0005694	Component	Chromosome	IEA
GO:0005730	Component	Nucleolus	IBA
GO:0005730	Component	Nucleolus	IDA	36695333
GO:0005730	Component	Nucleolus	IEA
GO:0007059	Process	Chromosome segregation	IMP	36695333
GO:0140014	Process	Mitotic nuclear division	IMP	36695333

Other IDs

• MIM: 611293
• HGNC: 28359
• e!Ensembl: ENSG00000110104

Protein

• UniProt ID: Q9H6F5
• Protein name: Coiled-coil domain-containing protein 86 (Cytokine-induced protein with coiled-coil domain)
• Protein function: Required for proper chromosome segregation during mitosis and error-free mitotic progression.
• PDB: 8FL0, 8FL2, 8FL3, 8FL4, 8INK, 8IPD, 8IPX, 8IPY, 8IR1, 8IR3
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF03879	Cgr1	236 → 342	Cgr1 family	Coiled-coil

• Sequence:

  MDTPLRRSRRLGGLRPESPESLTSVSRTRRALVEFESNPEETREPGSPPSVQRAGLGSPE
  RPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQPKP
  SEEAPKCSQDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLE
  LTPRAPGSPRGQHEPSKPPPAGETVTGGFGAKKRKGSSSQAPASKKLNKEELPVIPKGKP
  KSGRVWKDRSKKRFSQMLQDKPLRTSWQRKMKERQERKLAKDFARHLEEEKERRRQEKKQ
  RRAENLKRRLENERKAEVVQVIRNPAKLKRAKKKQLRSIEKRDTLALLQKQPPQQPAAKI
  

• Sequence length: 360