Gene Gene information from NCBI Gene database.
Entrez ID 79071
Gene name ELOVL fatty acid elongase 6
Gene symbol ELOVL6
Synonyms (NCBI Gene)
FACEFAELCEhELO2
Chromosome 4
Chromosome location 4q25
Summary Fatty acid elongases (EC 6.2.1.3), such as ELOVL6, use malonyl-CoA as a 2-carbon donor in the first and rate-limiting step of fatty acid elongation (Moon et al., 2001 [PubMed 11567032]).[supplied by OMIM, Mar 2008]
miRNA miRNA information provided by mirtarbase database.
429
miRTarBase ID miRNA Experiments Reference
MIRT006461 hsa-miR-204-5p ImmunofluorescenceMicroarrayqRT-PCRWestern blot 22523078
MIRT006463 hsa-miR-211-5p ImmunofluorescenceMicroarrayqRT-PCRWestern blot 22523078
MIRT006461 hsa-miR-204-5p ImmunofluorescenceMicroarrayqRT-PCRWestern blot 22523078
MIRT006463 hsa-miR-211-5p ImmunofluorescenceMicroarrayqRT-PCRWestern blot 22523078
MIRT017106 hsa-miR-335-5p Microarray 18185580
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
36
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 20937905, 32296183
GO:0005783 Component Endoplasmic reticulum IDA 20937905
GO:0005783 Component Endoplasmic reticulum IEA
GO:0005789 Component Endoplasmic reticulum membrane IBA
GO:0005789 Component Endoplasmic reticulum membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
611546 15829 ENSG00000170522
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9H5J4
Protein name Very long chain fatty acid elongase 6 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL6) (ELOVL fatty acid elongase 6) (ELOVL FA elongase 6) (Elongation of very long chain fatty acids protein 6) (Fatty acid elongase 2) (hELO2) (Fatty acyl-CoA elongase) (Lon
Protein function Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01151 ELO 25 262 GNS1/SUR4 family Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:20937905}.
Sequence
Sequence length 265
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Fatty acid elongation
Biosynthesis of unsaturated fatty acids
Metabolic pathways
Fatty acid metabolism
  Activation of gene expression by SREBF (SREBP)
Synthesis of very long-chain fatty acyl-CoAs