Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
79047
Gene name Gene Name - the full gene name approved by the HGNC.
Potassium channel tetramerization domain containing 15
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
KCTD15
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
19q13.11
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020375 hsa-miR-29c-3p Sequencing 20371350
MIRT021087 hsa-miR-186-5p Sequencing 20371350
MIRT024933 hsa-miR-215-5p Microarray 19074876
MIRT026293 hsa-miR-192-5p Microarray 19074876
MIRT050356 hsa-miR-25-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 25416956
GO:0007275 Process Multicellular organism development IEA
GO:0042802 Function Identical protein binding IPI 27152988
GO:0051260 Process Protein homooligomerization IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
615240 23297 ENSG00000153885
Protein
UniProt ID Q96SI1
Protein name BTB/POZ domain-containing protein KCTD15 (Potassium channel tetramerization domain-containing protein 15)
Protein function During embryonic development, it is involved in neural crest formation (By similarity). Inhibits AP2 transcriptional activity by interaction with its activation domain (PubMed:23382213). {ECO:0000250|UniProtKB:Q6DC02, ECO:0000269|PubMed:23382213
PDB 8PNM , 8PNR
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02214 BTB_2 58 150 BTB/POZ domain Domain
Sequence
MPHRKERPSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHI
DVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTS
KLLLPDDFKDFSLLYEEARYYQLQPMVREL
ERWQQEQEQRRRSRACDCLVVRVTPDLGER
IALSGEKALIEEVFPETGDVMCNSVNAGWNQDPTHVIRFPLNGYCRLNSVQVLERLFQRG
FSVAASCGGGVDSSQFSEYVLCREERRPQPTPTAVRIKQEPLD
Sequence length 283
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Obesity Obesity rs74315349, rs1474810899, rs121918111, rs796065034, rs753856820, rs796065035, rs121918112, rs104894023, rs137852821, rs1580764441, rs137852822, rs137852823, rs137852824, rs13447324, rs121913562
View all (27 more)
19079261
Unknown
Disease term Disease name Evidence References Source
Frontonasal Dysplasia frontonasal dysplasia GenCC
Mental Depression Mental Depression GWAS
Endometriosis Endometriosis GWAS
Metabolic Syndrome Metabolic Syndrome GWAS
Associations from Text Mining
Disease Name Relationship Type References
Adenoma Pleomorphic Associate 31861025
Anorexia Associate 28948079
Anorexia Nervosa Associate 28948079
Bulimia Nervosa Associate 28948079
Cardiovascular Diseases Associate 19910641
Craniofacial Abnormalities Associate 38296633
Diabetes Mellitus Associate 34521919
Ectodermal Dysplasia Associate 38296633
Feeding and Eating Disorders Associate 28948079
Frontonasal dysplasia Associate 38296633