Gene Gene information from NCBI Gene database.
Entrez ID 79016
Gene name DET1 and DDB1 associated 1
Gene symbol DDA1
Synonyms (NCBI Gene)
C19orf58PCIA1
Chromosome 19
Chromosome location 19p13.11
miRNA miRNA information provided by mirtarbase database.
710
miRTarBase ID miRNA Experiments Reference
MIRT613168 hsa-miR-140-3p HITS-CLIP 23824327
MIRT613167 hsa-miR-2682-5p HITS-CLIP 23824327
MIRT613166 hsa-miR-34b-5p HITS-CLIP 23824327
MIRT613165 hsa-miR-449c-5p HITS-CLIP 23824327
MIRT613164 hsa-miR-4514 HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
8
GO ID Ontology Definition Evidence Reference
GO:0000209 Process Protein polyubiquitination IMP 31686031
GO:0005515 Function Protein binding IPI 16949367, 20562859, 25416956, 30564455, 32296183, 32814053, 35271311
GO:0005654 Component Nucleoplasm TAS
GO:0016567 Process Protein ubiquitination IEA
GO:0032434 Process Regulation of proteasomal ubiquitin-dependent protein catabolic process IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9BW61
Protein name DET1- and DDB1-associated protein 1 (Placenta cross-immune reaction antigen 1) (PCIA-1)
Protein function Functions as a component of numerous distinct DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:17452440, PubMed:28302793, PubMed:284373
PDB 6DSZ , 6PAI , 6Q0R , 6Q0V , 6Q0W , 6SJ7 , 6UD7 , 6UE5 , 8G46 , 8QH5 , 8ROX , 8ROY , 8TL6 , 9BZ0 , 9DHD , 9FD2
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF10172 DDA1 3 65 Det1 complexing ubiquitin ligase Family
Sequence
Sequence length 102
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neddylation