GDAP1L1 (ganglioside induced differentiation associated protein 1 like 1)

Gene

• Entrez ID: 78997
• Gene name: Ganglioside induced differentiation associated protein 1 like 1
• Gene symbol: GDAP1L1
• Synonyms (NCBI Gene): dJ881L22.1, dJ995J12.1.1
• Chromosome: 20
• Chromosome location: 20q13.12
• Summary: The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein te

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT668185	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT636510	hsa-miR-3183	HITS-CLIP	23824327
MIRT636509	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT636508	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT636507	hsa-miR-3615	HITS-CLIP	23824327
MIRT636506	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT636505	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT636504	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT636503	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT636502	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT636501	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT668185	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT636500	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT636499	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT636498	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT636497	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT636496	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT668184	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT668183	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT668182	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT636495	hsa-miR-3158-3p	HITS-CLIP	23824327
MIRT636510	hsa-miR-3183	HITS-CLIP	23824327
MIRT636509	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT636508	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT636507	hsa-miR-3615	HITS-CLIP	23824327
MIRT636506	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT636505	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT636504	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT636503	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT636502	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT636501	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT636500	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT636499	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT636498	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT636497	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT636496	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT636495	hsa-miR-3158-3p	HITS-CLIP	23824327
MIRT668185	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT636510	hsa-miR-3183	HITS-CLIP	23824327
MIRT636509	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT636508	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT636507	hsa-miR-3615	HITS-CLIP	23824327
MIRT636506	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT636505	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT636504	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT636503	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT636502	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT636501	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT668185	hsa-miR-411-5p	HITS-CLIP	23824327
MIRT636500	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT636499	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT636498	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT636497	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT636496	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT668184	hsa-miR-4768-5p	HITS-CLIP	23824327
MIRT668183	hsa-miR-6833-3p	HITS-CLIP	23824327
MIRT668182	hsa-miR-6809-3p	HITS-CLIP	23824327
MIRT636495	hsa-miR-3158-3p	HITS-CLIP	23824327
MIRT636510	hsa-miR-3183	HITS-CLIP	23824327
MIRT636509	hsa-miR-4723-3p	HITS-CLIP	23824327
MIRT636508	hsa-miR-6769b-3p	HITS-CLIP	23824327
MIRT636507	hsa-miR-3615	HITS-CLIP	23824327
MIRT636506	hsa-miR-7110-3p	HITS-CLIP	23824327
MIRT636505	hsa-miR-6817-3p	HITS-CLIP	23824327
MIRT636504	hsa-miR-130b-5p	HITS-CLIP	23824327
MIRT636503	hsa-miR-516a-3p	HITS-CLIP	23824327
MIRT636502	hsa-miR-516b-3p	HITS-CLIP	23824327
MIRT636501	hsa-miR-7162-5p	HITS-CLIP	23824327
MIRT636500	hsa-miR-7111-3p	HITS-CLIP	23824327
MIRT636499	hsa-miR-6780a-3p	HITS-CLIP	23824327
MIRT636498	hsa-miR-6881-3p	HITS-CLIP	23824327
MIRT636497	hsa-miR-6873-3p	HITS-CLIP	23824327
MIRT636496	hsa-miR-4753-3p	HITS-CLIP	23824327
MIRT636495	hsa-miR-3158-3p	HITS-CLIP	23824327
MIRT1015332	hsa-miR-1224-3p	CLIP-seq
MIRT1015333	hsa-miR-1260	CLIP-seq
MIRT1015334	hsa-miR-1260b	CLIP-seq
MIRT1015335	hsa-miR-1280	CLIP-seq
MIRT1015336	hsa-miR-129-5p	CLIP-seq
MIRT1015337	hsa-miR-1914	CLIP-seq
MIRT1015338	hsa-miR-2355-3p	CLIP-seq
MIRT1015339	hsa-miR-3132	CLIP-seq
MIRT1015340	hsa-miR-3190	CLIP-seq
MIRT1015341	hsa-miR-377	CLIP-seq
MIRT1015342	hsa-miR-4646-3p	CLIP-seq
MIRT1015343	hsa-miR-4650-3p	CLIP-seq
MIRT1015344	hsa-miR-4652-3p	CLIP-seq
MIRT1015345	hsa-miR-4766-5p	CLIP-seq
MIRT1015346	hsa-miR-513a-5p	CLIP-seq
MIRT1015347	hsa-miR-676	CLIP-seq
MIRT1015348	hsa-miR-7	CLIP-seq
MIRT2538022	hsa-miR-1184	CLIP-seq
MIRT2538023	hsa-miR-4286	CLIP-seq
MIRT2538024	hsa-miR-4418	CLIP-seq
MIRT2538025	hsa-miR-509-3-5p	CLIP-seq
MIRT2538026	hsa-miR-509-5p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0006749	Process	Glutathione metabolic process	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q96MZ0
• Protein name: Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1-L1)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13417	GST_N_3	49 → 126	Glutathione S-transferase, N-terminal domain	Domain
  PF13410	GST_C_2	179 → 304		Domain

• Sequence:

  MATPNNLTPTNCSWWPISALESDAAKPAEAPDAPEAASPAHWPRESLVLYHWTQSFSSQK
  VRLVIAEKGLVCEERDVSLPQSEHKEPWFMRLNLGEEVPVIIHRDNIISDYDQIIDYVER
  TFTGEHVVALMPEVGSLQHARVLQYRELLDALPMDAYTHGCILHPELTTDSMIPKYATAE
  IRRHLANATTDLMKLDHEEEPQLSEPYLSKQKKLMAKILEHDDVSYLKKILGELAMVLDQ
  IEAELEKRKLENEGQKCELWLCGCAFTLADVLLGATLHRLKFLGLSKKYWEDGSRPNLQS
  FFERVQRRFAFRKVLGDIHTTLLSAVIPNAFRLVKRKPPSFFGASFLMGSLGGMGYFAYW
  YLKKKYI

• Sequence length: 367

Associated diseases

Causal
Disease term	Disease name	dbSNP ID	References
Colorectal cancer	Colorectal Carcinoma	rs137854568, rs137854573, rs137854575, rs387906234, rs121908380, rs121908702, rs267606674, rs794729661, rs121909055, rs281865417, rs267606884, rs28934575, rs587776769, rs104893815, rs587776800, rs63750198, rs63751109, rs863223312, rs63750710, rs63751615, rs63750206, rs63750781, rs63750899, rs63750691, rs63750217, rs121912965, rs63749939, rs63751194, rs63750693, rs63750540, rs63751221, rs193922370, rs80359596, rs397514632, rs483352909, rs200495564, rs397514684, rs397516436, rs398122386, rs79512956, rs74953290, rs587779001, rs63750677, rs63749837, rs267607816, rs63751715, rs267607819, rs267607815, rs267607822, rs63749906, rs587778883, rs63750472, rs63751012, rs63750715, rs63750580, rs267607706, rs267607709, rs267607710, rs587778894, rs63750749, rs63750483, rs63751015, rs63751153, rs63751094, rs63751118, rs63750316, rs63749981, rs587778906, rs267607821, rs587778908, rs63750020, rs587778909, rs63750713, rs267607825, rs63751592, rs281864936, rs587778913, rs587778914, rs63749795, rs63750855, rs63749916, rs63749923, rs63751472, rs63751689, rs267607832, rs267607837, rs267607836, rs587778923, rs63750028, rs587778928, rs587778929, rs587778930, rs63751277, rs587778933, rs267607842, rs267607843, rs63750192, rs587778934, rs63750193, rs587778937, rs587778938, rs267607845, rs63751244, rs63751393, rs63751460, rs267607849, rs267607853, rs267607856, rs267607850, rs63751657, rs267607854, rs267607852, rs587778942, rs63750309, rs63750587, rs63749863, rs63751486, rs63750016, rs63749868, rs63750375, rs63750035, rs63750604, rs63750386, rs63750150, rs63750486, rs63751428, rs267607866, rs63749986, rs63751594, rs63750152, rs63750850, rs267607867, rs267607868, rs63751632, rs267607871, rs63751892, rs587778956, rs63750469, rs587778958, rs63749792, rs267607875, rs63751255, rs281864938, rs63751202, rs63750726, rs63751310, rs63749900, rs587778964, rs267607879, rs267607878, rs587778966, rs267607883, rs267607887, rs63750061, rs63750663, rs587778968, rs587778971, rs63750809, rs63749867, rs63750864, rs587778972, rs63751275, rs267607718, rs267607722, rs63750769, rs267607717, rs587778973, rs267607716, rs267607720, rs63749995, rs63750859, rs587778975, rs63750114, rs587778976, rs63750603, rs267607889, rs267607723, rs63750561, rs63750499, rs63751642, rs63751022, rs587778981, rs63750971, rs267607898, rs267607906, rs267607903, rs587778989, rs587778992, rs267607894, rs267607901, rs267607892, rs63750437, rs587778997, rs587778998, rs63750005, rs63750641, rs63751421, rs11541859, rs63750266, rs111052004, rs267607726, rs267607727, rs63750453, rs267607734, rs267607735, rs63751665, rs267607736, rs267607732, rs63749816, rs63750539, rs267607739, rs587779006, rs587779008, rs267607745, rs267607742, rs63751595, rs267607743, rs587779010, rs587779012, rs63750057, rs63749818, rs63751124, rs587779014, rs587779015, rs63749820, rs63751302, rs267607750, rs267607751, rs267607749, rs63750891, rs63749959, rs63749804, rs267607765, rs267607760, rs587779021, rs267607759, rs63750515, rs587779023, rs63751021, rs63751480, rs267607772, rs267607773, rs587779024, rs63751653, rs587779027, rs267607767, rs587779029, rs63750706, rs63750385, rs267607774, rs267607778, rs267607780, rs587779034, rs63751711, rs267607784, rs587779035, rs63750823, rs63750822, rs267607787, rs63750303, rs63749839, rs63749827, rs267607789, rs267607790, rs267607791, rs267607786, rs267607771, rs267607795, rs267607794, rs267607788, rs267607799, rs267607801, rs587779045, rs63750034, rs587779047, rs63750216, rs63751707, rs63751598, rs267607803, rs267607777, rs63750144, rs267607805, rs63750547, rs63750489, rs63750993, rs587779054, rs63751259, rs63749926, rs63750796, rs587779058, rs63750745, rs63750582, rs180177084, rs587779866, rs200389141, rs587779950, rs587780104, rs587780183, rs587778536, rs587780683, rs587781554, rs267607712, rs587777627, rs587783057, rs730881734, rs41542214, rs730881273, rs786203456, rs786201990, rs786202767, rs748005072, rs786204317, rs786204318, rs797045117, rs63750549, rs863225383, rs863225384, rs863225373, rs863225376, rs863225377, rs863225378, rs863225379, rs863225380, rs863225381, rs63750059, rs267607823, rs864622457, rs869312767, rs869312753, rs876661059, rs876658915, rs876658923, rs876660860, rs876660822, rs876660458, rs876660214, rs876658657, rs876658247, rs876659226, rs876658821, rs876660589, rs876659068, rs876659681, rs876659608, rs878853794, rs878853778, rs878853780, rs878853785, rs886039423, rs886039424, rs1057517543, rs1057517541, rs756843954, rs1057517617, rs1057517558, rs1057519256, rs1060500689, rs764085979, rs1060500707, rs1060500699, rs1060500706, rs1060500703, rs1064795341, rs1064793607, rs1064794348, rs1064795441, rs1064794373, rs1064793172, rs1064794122, rs1064795515, rs1064794331, rs63750978, rs1114167435, rs1553641362, rs63751448, rs1553648029, rs1553648058, rs587778903, rs1553653237, rs1553664353, rs267607744, rs1553647995, rs1553648047, rs1553653084, rs1553663750, rs1553664436, rs1553488015, rs1553637293, rs63750310, rs63750443, rs63751596, rs1553646681, rs550890395, rs1064796057, rs1553642079, rs1553648023, rs587782087, rs746536721, rs1553653037, rs1248251121, rs1553646602, rs1434898623, rs1553665683, rs1553648068, rs1553645331, rs1553644123, rs1553658246, rs1553651299, rs1553648149, rs1553663159, rs1302248679, rs1553664119, rs1553658009, rs1553665977, rs1416171624, rs1553663834, rs1553664617, rs1553664702, rs1553647969, rs1553648040, rs1437454428, rs1553641273, rs63751101, rs1553646764, rs1553648225, rs1554082118, rs1553648201, rs1553638868, rs1553665866, rs376736188, rs1553642707, rs1553645226, rs1553652883, rs63751435, rs1553653115, rs1553653195, rs63750300, rs1553662622, rs1553658104, rs1553648220, rs1559544064, rs63750584, rs267608083, rs1559551570, rs1559575107, rs1559553501, rs1565986506, rs1559524405, rs1559553492, rs1559554339, rs1559588540, rs1559558071, rs761329565, rs1559521039, rs1559574795, rs1567221417, rs1559578422, rs1481129490, rs1570714352, rs779783209, rs1575376830, rs1575469070, rs1575537843, rs1575620443, rs1575621506, rs587779022, rs1575414904, rs1575449093, rs1575469505, rs1575536254, rs1575537933, rs1575632112, rs1575639851, rs1575441094, rs1575449402, rs267607831, rs2081922847, rs2083403132, rs2085415927, rs2085469647, rs2043913790, rs147542208
Diabetes mellitus	Diabetes Mellitus, Non-Insulin-Dependent	rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237, rs80356613, rs387906407, rs151344623, rs28938469, rs28936371, rs137852672, rs80356637, rs80356642, rs80356653, rs137852673, rs137852674, rs80356634, rs80356651, rs193929360, rs137853334, rs137853335, rs137853336, rs1600731198, rs137853338, rs121964882, rs121964883, rs387906511, rs121964884, rs121964885, rs2147483647, rs387906512, rs121964887, rs121964888, rs121964889, rs121964890, rs121964891, rs28934878, rs74315383, rs121964893, rs886037620, rs886037621, rs121434593, rs121913150, rs587776825, rs137853236, rs2135842335, rs137853237, rs137853238, rs2135818776, rs1566092470, rs1463923467, rs137853243, rs137853244, rs2135839114, rs137853245, rs2135847417, rs121918407, rs104894005, rs104894006, rs80356655, rs104894008, rs104894009, rs104894010, rs104894011, rs80356654, rs104894016, rs193929376, rs193929374, rs193929375, rs193929373, rs80356669, rs80356664, rs193929366, rs1048095, rs193929355, rs193929356, rs1259467443, rs104893642, rs387906777, rs193922396, rs193922400, rs193922401, rs137852676, rs193922407, rs193922638, rs193922257, rs193922258, rs193922259, rs193922260, rs193922261, rs193922262, rs193922263, rs193922264, rs193922265, rs193922268, rs193921338, rs193922269, rs193922272, rs193922273, rs193922275, rs193922278, rs193922279, rs193922280, rs193922281, rs193922282, rs193922283, rs193922284, rs193922286, rs193922287, rs193922289, rs193922291, rs193922295, rs193922297, rs193922300, rs193922302, rs193922303, rs193922308, rs193922313, rs193922314, rs144723656, rs193922315, rs193922316, rs193922317, rs148311934, rs193922319, rs193922320, rs193922326, rs193922329, rs193922330, rs193922331, rs193922335, rs193922336, rs193922338, rs193922340, rs193922341, rs193922471, rs193922475, rs193922476, rs193922479, rs80356663, rs193922355, rs193922356, rs193922576, rs193922578, rs193922582, rs193922588, rs193922592, rs193922594, rs193922596, rs386134267, rs193922598, rs193922599, rs193922600, rs193922604, rs193922605, rs397514580, rs397515519, rs267601516, rs587780343, rs587780345, rs587780346, rs587780347, rs587780357, rs148954387, rs587783672, rs587783669, rs786204676, rs794727236, rs151344624, rs794727775, rs794727839, rs199946797, rs869320673, rs796065047, rs759072800, rs797045595, rs797045209, rs797045207, rs797045213, rs863225280, rs149703259, rs864321656, rs139964066, rs777870079, rs878853246, rs769268803, rs886039380, rs886041392, rs886041391, rs886042610, rs143064649, rs1057516192, rs746480424, rs1057516281, rs576684889, rs754728827, rs1057520291, rs1057520779, rs893256143, rs1057520504, rs1057524790, rs1057524902, rs1057524904, rs1057524905, rs764232985, rs1064793998, rs1064794268, rs769086289, rs369429452, rs1085307913, rs1131691416, rs765432081, rs1131692182, rs748749585, rs1554335441, rs762263694, rs1312678560, rs767565869, rs1375656631, rs1554335391, rs1360415315, rs1554335616, rs1554335752, rs1554909277, rs769518471, rs757171524, rs768951263, rs762703502, rs1555212248, rs1555212359, rs1555813319, rs1555816654, rs371977235, rs1415041911, rs1554334894, rs1260178539, rs1554335421, rs1555211904, rs779184183, rs1554335564, rs200670692, rs1400535021, rs1554334872, rs1555212749, rs1553876668, rs1553878211, rs954727530, rs1554924035, rs372307320, rs925231098, rs1554913069, rs1554933565, rs766431403, rs746714109, rs751279984, rs770664202, rs1008906426, rs758844607, rs1554924540, rs1566092307, rs753998395, rs1565885935, rs1167124132, rs1376796469, rs556436603, rs1562715657, rs1486280029, rs1564869850, rs755259997, rs769569410, rs1172328722, rs1286294151, rs1375557127, rs1568731279, rs1562715426, rs556581174, rs1564865302, rs1565886545, rs1568724014, rs1392795567, rs781260712, rs1562719705, rs1382448285, rs1564977373, rs750586210, rs1598842892, rs1583592247, rs780612692, rs1593060859, rs1476637197, rs751279776, rs1593060890, rs1191912908, rs1167675604, rs1583601110, rs1593058932, rs778611627, rs753296261	21874001

Unknown
Disease term	Disease name	Evidence	References	Source
Diabetes	Diabetes			GWAS

Associations from Text Mining
Disease Name	Relationship Type	References
Dyskeratosis Congenita	Associate	29696773
Mood Disorders	Associate	29696773
Teratozoospermia	Associate	25762640