FZD5 (frizzled class receptor 5)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7855 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Frizzled class receptor 5 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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FZD5 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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C2orf31, HFZ5, MCOPCB11 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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MCOPCB11 |
Chromosome
Chromosome number
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2 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2q33.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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Members of the `frizzled` gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand. [provided by RefSeq, Jul 2008] |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q13467 | |||||||||||||||
Protein name | Frizzled-5 (Fz-5) (hFz5) (FzE5) | |||||||||||||||
Protein function | Receptor for Wnt proteins (PubMed:10097073, PubMed:20530549, PubMed:26908622, PubMed:9054360). Functions in the canonical Wnt/beta-catenin signaling pathway. In vitro activates WNT2, WNT10B, WNT5A, but not WNT2B or WNT4 signaling (By similarity) | |||||||||||||||
PDB | 5URY , 5URZ , 6O39 , 6WW2 | |||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 585 | |||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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