Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
7812
Gene name Gene Name - the full gene name approved by the HGNC.
Cold shock domain containing E1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
CSDE1
Synonyms (NCBI Gene) Gene synonyms aliases
D1S155E, UNR
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p13.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT019618 hsa-miR-340-5p Sequencing 20371350
MIRT031909 hsa-miR-16-5p Proteomics 18668040
MIRT050445 hsa-miR-23a-3p CLASH 23622248
MIRT049113 hsa-miR-92a-3p CLASH 23622248
MIRT049113 hsa-miR-92a-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000932 Component P-body IEA
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0005515 Function Protein binding IPI 25416956, 27342281
GO:0005794 Component Golgi apparatus IDA
GO:0005829 Component Cytosol IDA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
191510 29905 ENSG00000009307
Protein
UniProt ID O75534
Protein name Cold shock domain-containing protein E1 (N-ras upstream gene protein) (Protein UNR)
Protein function RNA-binding protein involved in translationally coupled mRNA turnover (PubMed:11051545, PubMed:15314026). Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by t
PDB 1WFQ , 1X65 , 2YTV , 2YTX , 2YTY
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00313 CSD 26 90 Domain
PF00313 CSD 186 248 Domain
PF00313 CSD 349 413 Domain
PF00313 CSD 519 582 Domain
PF00313 CSD 674 738 Domain
PF12901 SUZ-C 756 788 SUZ-C motif Domain
Sequence
MSFDPNLLHNNGHNGYPNGTSAALRETGVIEKLLTSYGFIQCSERQARLFFHCSQYNGNL
QDLKVGDDVEFEVSSDRRTGKPIAVKLVKI
KQEILPEERMNGQVVCAVPHNLESKSPAAP
GQSPTGSVCYERNGEVFYLTYTPEDVEGNVQLETGDKINFVIDNNKHTGAVSARNIMLLK
KKQARCQGVVCAMKEAFGFIERGDVVKEIFFHYSEFKGDLETLQPGDDVEFTIKDRNGKE
VATDVRLL
PQGTVIFEDISIEHFEGTVTKVIPKVPSKNQNDPLPGRIKVDFVIPKELPFG
DKDTKSKVTLLEGDHVRFNISTDRRDKLERATNIEVLSNTFQFTNEAREMGVIAAMRDGF
GFIKCVDRDVRMFFHFSEILDGNQLHIADEVEFTVVPDMLSAQRNHAIRIKKL
PKGTVSF
HSHSDHRFLGTVEKEATFSNPKTTSPNKGKEKEAEDGIIAYDDCGVKLTIAFQAKDVEGS
TSPQIGDKVEFSISDKQRPGQQVATCVRLLGRNSNSKRLLGYVATLKDNFGFIETANHDK
EIFFHYSEFSGDVDSLELGDMVEYSLSKGKGNKVSAEKVNKT
HSVNGITEEADPTIYSGK
VIRPLRSVDPTQTEYQGMIEIVEEGDMKGEVYPFGIVGMANKGDCLQKGESVKFQLCVLG
QNAQTMAYNITPLRRATVECVKDQFGFINYEVGDSKKLFFHVKEVQDGIELQAGDEVEFS
VILNQRTGKCSACNVWRV
CEGPKAVAAPRPDRLVNRLKNITLDDASAPRLMVLRQPRGPD
NSMGFGAE
RKIRQAGVID
Sequence length 798
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Autism Autistic Disorder rs121964908, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699
View all (8 more)
24189344, 31579823
Developmental delay Global developmental delay rs28941770, rs199469464, rs281865469, rs143747297, rs398123009, rs587777428, rs786205133, rs606231459, rs797044854, rs797045027, rs864309504, rs878853160, rs886039902, rs886042046, rs886041291
View all (32 more)
31579823
Mental retardation Intellectual Disability rs5742905, rs267607136, rs267607137, rs2131714307, rs267607038, rs267607042, rs80338685, rs137853127, rs80338815, rs28940893, rs387906309, rs121908096, rs121908099, rs587784365, rs121918315
View all (1024 more)
31579823
Unknown
Disease term Disease name Evidence References Source
Neurodevelopmental Disorders complex neurodevelopmental disorder GenCC
Schizophrenia Schizophrenia GWAS
Associations from Text Mining
Disease Name Relationship Type References
Aphasia Broca Associate 35026469
Arthritis Rheumatoid Associate 12223111
Autistic Disorder Associate 35026469
Breast Neoplasms Associate 24098497, 35923244
Carcinoma Hepatocellular Associate 36354136
Carcinoma Pancreatic Ductal Associate 28763470
Developmental Disabilities Associate 35026469
Eye Abnormalities Associate 35026469
Intellectual Disability Associate 35026469
Lung Neoplasms Associate 32808651