Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	7799
Gene name	PR/SET domain 2
Gene symbol	PRDM2
Synonyms (NCBI Gene)	HUMHOXY1KMT8KMT8AMTB-ZFRIZRIZ1RIZ2
Chromosome	1
Chromosome location	1p36.21
Summary	This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 ge

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SNP ID	Visualize variation	Clinical significance	Consequence
rs1570018597	TAGTACAGAAAGC>-	Likely-pathogenic	Intron variant, non coding transcript variant, frameshift variant, coding sequence variant

392

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miRTarBase ID	miRNA	Experiments	Reference
MIRT038603	hsa-miR-106b-3p	CLASH	23622248
MIRT626956	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT626955	hsa-miR-4668-3p	HITS-CLIP	23824327
MIRT626954	hsa-miR-605-5p	HITS-CLIP	23824327
MIRT626953	hsa-miR-188-5p	HITS-CLIP	23824327
MIRT626952	hsa-miR-6866-3p	HITS-CLIP	23824327
MIRT626951	hsa-miR-4504	HITS-CLIP	23824327
MIRT626950	hsa-miR-542-3p	HITS-CLIP	23824327
MIRT626949	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT626948	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT626947	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT180470	hsa-miR-541-5p	PAR-CLIP	20371350
MIRT513543	hsa-miR-28-5p	PAR-CLIP	20371350
MIRT513542	hsa-miR-3139	PAR-CLIP	20371350
MIRT513541	hsa-miR-708-5p	PAR-CLIP	20371350
MIRT513540	hsa-miR-5681a	PAR-CLIP	20371350
MIRT513539	hsa-miR-6730-5p	PAR-CLIP	20371350
MIRT513538	hsa-miR-3656	PAR-CLIP	20371350
MIRT513537	hsa-miR-8065	PAR-CLIP	20371350
MIRT513536	hsa-miR-145-5p	PAR-CLIP	20371350
MIRT513535	hsa-miR-5195-3p	PAR-CLIP	20371350
MIRT513534	hsa-miR-488-3p	PAR-CLIP	20371350
MIRT180470	hsa-miR-541-5p	PAR-CLIP	23446348
MIRT513543	hsa-miR-28-5p	PAR-CLIP	23446348
MIRT513542	hsa-miR-3139	PAR-CLIP	23446348
MIRT513541	hsa-miR-708-5p	PAR-CLIP	23446348
MIRT513540	hsa-miR-5681a	PAR-CLIP	23446348
MIRT513539	hsa-miR-6730-5p	PAR-CLIP	23446348
MIRT513538	hsa-miR-3656	PAR-CLIP	23446348
MIRT513537	hsa-miR-8065	PAR-CLIP	23446348
MIRT513536	hsa-miR-145-5p	PAR-CLIP	23446348
MIRT513535	hsa-miR-5195-3p	PAR-CLIP	23446348
MIRT513534	hsa-miR-488-3p	PAR-CLIP	23446348
MIRT497014	hsa-miR-6854-5p	PAR-CLIP	22291592
MIRT497013	hsa-miR-203b-3p	PAR-CLIP	22291592
MIRT497012	hsa-miR-7154-5p	PAR-CLIP	22291592
MIRT626956	hsa-miR-548c-3p	HITS-CLIP	23824327
MIRT626955	hsa-miR-4668-3p	HITS-CLIP	23824327
MIRT626954	hsa-miR-605-5p	HITS-CLIP	23824327
MIRT626953	hsa-miR-188-5p	HITS-CLIP	23824327
MIRT626952	hsa-miR-6866-3p	HITS-CLIP	23824327
MIRT626951	hsa-miR-4504	HITS-CLIP	23824327
MIRT626950	hsa-miR-542-3p	HITS-CLIP	23824327
MIRT626949	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT626948	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT626947	hsa-miR-4668-5p	HITS-CLIP	23824327
MIRT180470	hsa-miR-541-5p	PAR-CLIP	20371350
MIRT513543	hsa-miR-28-5p	PAR-CLIP	20371350
MIRT513542	hsa-miR-3139	PAR-CLIP	20371350
MIRT513541	hsa-miR-708-5p	PAR-CLIP	20371350
MIRT513540	hsa-miR-5681a	PAR-CLIP	20371350
MIRT513539	hsa-miR-6730-5p	PAR-CLIP	20371350
MIRT513538	hsa-miR-3656	PAR-CLIP	20371350
MIRT513537	hsa-miR-8065	PAR-CLIP	20371350
MIRT513536	hsa-miR-145-5p	PAR-CLIP	20371350
MIRT513535	hsa-miR-5195-3p	PAR-CLIP	20371350
MIRT513534	hsa-miR-488-3p	PAR-CLIP	20371350
MIRT180470	hsa-miR-541-5p	PAR-CLIP	23446348
MIRT513543	hsa-miR-28-5p	PAR-CLIP	23446348
MIRT513542	hsa-miR-3139	PAR-CLIP	23446348
MIRT513541	hsa-miR-708-5p	PAR-CLIP	23446348
MIRT513540	hsa-miR-5681a	PAR-CLIP	23446348
MIRT513539	hsa-miR-6730-5p	PAR-CLIP	23446348
MIRT513538	hsa-miR-3656	PAR-CLIP	23446348
MIRT513537	hsa-miR-8065	PAR-CLIP	23446348
MIRT513536	hsa-miR-145-5p	PAR-CLIP	23446348
MIRT513535	hsa-miR-5195-3p	PAR-CLIP	23446348
MIRT513534	hsa-miR-488-3p	PAR-CLIP	23446348
MIRT497014	hsa-miR-6854-5p	PAR-CLIP	22291592
MIRT497013	hsa-miR-203b-3p	PAR-CLIP	22291592
MIRT497012	hsa-miR-7154-5p	PAR-CLIP	22291592
MIRT1260166	hsa-let-7a	CLIP-seq
MIRT1260167	hsa-let-7b	CLIP-seq
MIRT1260168	hsa-let-7c	CLIP-seq
MIRT1260169	hsa-let-7d	CLIP-seq
MIRT1260170	hsa-let-7e	CLIP-seq
MIRT1260171	hsa-let-7f	CLIP-seq
MIRT1260172	hsa-let-7g	CLIP-seq
MIRT1260173	hsa-let-7i	CLIP-seq
MIRT1260174	hsa-miR-125a-5p	CLIP-seq
MIRT1260175	hsa-miR-125b	CLIP-seq
MIRT1260176	hsa-miR-1283	CLIP-seq
MIRT1260177	hsa-miR-151-5p	CLIP-seq
MIRT1260178	hsa-miR-151b	CLIP-seq
MIRT1260179	hsa-miR-197	CLIP-seq
MIRT1260180	hsa-miR-203	CLIP-seq
MIRT1260181	hsa-miR-2052	CLIP-seq
MIRT1260182	hsa-miR-3065-5p	CLIP-seq
MIRT1260183	hsa-miR-3120-3p	CLIP-seq
MIRT1260184	hsa-miR-3121-5p	CLIP-seq
MIRT1260185	hsa-miR-3126-3p	CLIP-seq
MIRT1260186	hsa-miR-3129-3p	CLIP-seq
MIRT1260187	hsa-miR-3176	CLIP-seq
MIRT1260188	hsa-miR-3529	CLIP-seq
MIRT1260189	hsa-miR-3609	CLIP-seq
MIRT1260190	hsa-miR-3613-3p	CLIP-seq
MIRT1260191	hsa-miR-3616-5p	CLIP-seq
MIRT1260192	hsa-miR-362-5p	CLIP-seq
MIRT1260193	hsa-miR-3647-5p	CLIP-seq
MIRT1260194	hsa-miR-3663-5p	CLIP-seq
MIRT1260195	hsa-miR-369-3p	CLIP-seq
MIRT1260196	hsa-miR-371b-3p	CLIP-seq
MIRT1260197	hsa-miR-374a	CLIP-seq
MIRT1260198	hsa-miR-374b	CLIP-seq
MIRT1260199	hsa-miR-374c	CLIP-seq
MIRT1260200	hsa-miR-379	CLIP-seq
MIRT1260201	hsa-miR-382	CLIP-seq
MIRT1260202	hsa-miR-3922-3p	CLIP-seq
MIRT1260203	hsa-miR-3927	CLIP-seq
MIRT1260204	hsa-miR-3942-3p	CLIP-seq
MIRT1260205	hsa-miR-4257	CLIP-seq
MIRT1260206	hsa-miR-4260	CLIP-seq
MIRT1260207	hsa-miR-4275	CLIP-seq
MIRT1260208	hsa-miR-431	CLIP-seq
MIRT1260209	hsa-miR-4319	CLIP-seq
MIRT1260210	hsa-miR-4451	CLIP-seq
MIRT1260211	hsa-miR-4453	CLIP-seq
MIRT1260212	hsa-miR-4458	CLIP-seq
MIRT1260213	hsa-miR-4464	CLIP-seq
MIRT1260214	hsa-miR-4473	CLIP-seq
MIRT1260215	hsa-miR-4476	CLIP-seq
MIRT1260216	hsa-miR-4495	CLIP-seq
MIRT1260217	hsa-miR-4500	CLIP-seq
MIRT1260218	hsa-miR-4538	CLIP-seq
MIRT1260219	hsa-miR-4650-3p	CLIP-seq
MIRT1260220	hsa-miR-4670-3p	CLIP-seq
MIRT1260221	hsa-miR-4676-5p	CLIP-seq
MIRT1260222	hsa-miR-4695-3p	CLIP-seq
MIRT1260223	hsa-miR-4732-3p	CLIP-seq
MIRT1260224	hsa-miR-4748	CLIP-seq
MIRT1260225	hsa-miR-4753-3p	CLIP-seq
MIRT1260226	hsa-miR-4762-5p	CLIP-seq
MIRT1260227	hsa-miR-495	CLIP-seq
MIRT1260228	hsa-miR-500b	CLIP-seq
MIRT1260229	hsa-miR-501-5p	CLIP-seq
MIRT1260230	hsa-miR-512-3p	CLIP-seq
MIRT1260231	hsa-miR-520f	CLIP-seq
MIRT1260232	hsa-miR-545	CLIP-seq
MIRT1260233	hsa-miR-548ah	CLIP-seq
MIRT1260234	hsa-miR-548t	CLIP-seq
MIRT1260235	hsa-miR-573	CLIP-seq
MIRT1260236	hsa-miR-575	CLIP-seq
MIRT1260237	hsa-miR-580	CLIP-seq
MIRT1260238	hsa-miR-582-5p	CLIP-seq
MIRT1260239	hsa-miR-606	CLIP-seq
MIRT1260240	hsa-miR-655	CLIP-seq
MIRT1260241	hsa-miR-670	CLIP-seq
MIRT1260242	hsa-miR-9	CLIP-seq
MIRT1260243	hsa-miR-938	CLIP-seq
MIRT1260244	hsa-miR-942	CLIP-seq
MIRT1260245	hsa-miR-98	CLIP-seq
MIRT1260166	hsa-let-7a	CLIP-seq
MIRT1260167	hsa-let-7b	CLIP-seq
MIRT1260168	hsa-let-7c	CLIP-seq
MIRT1260169	hsa-let-7d	CLIP-seq
MIRT1260170	hsa-let-7e	CLIP-seq
MIRT1260171	hsa-let-7f	CLIP-seq
MIRT1260172	hsa-let-7g	CLIP-seq
MIRT1260173	hsa-let-7i	CLIP-seq
MIRT1552547	hsa-miR-144	CLIP-seq
MIRT1552548	hsa-miR-146a	CLIP-seq
MIRT1552549	hsa-miR-146b-5p	CLIP-seq
MIRT1260190	hsa-miR-3613-3p	CLIP-seq
MIRT1260191	hsa-miR-3616-5p	CLIP-seq
MIRT1260193	hsa-miR-3647-5p	CLIP-seq
MIRT1260203	hsa-miR-3927	CLIP-seq
MIRT1260205	hsa-miR-4257	CLIP-seq
MIRT1260212	hsa-miR-4458	CLIP-seq
MIRT1260217	hsa-miR-4500	CLIP-seq
MIRT1260220	hsa-miR-4670-3p	CLIP-seq
MIRT1260235	hsa-miR-573	CLIP-seq
MIRT1260237	hsa-miR-580	CLIP-seq
MIRT1552550	hsa-miR-589	CLIP-seq
MIRT1260245	hsa-miR-98	CLIP-seq
MIRT2076608	hsa-miR-1207-3p	CLIP-seq
MIRT2076609	hsa-miR-1258	CLIP-seq
MIRT2076610	hsa-miR-1290	CLIP-seq
MIRT2076611	hsa-miR-3159	CLIP-seq
MIRT2076612	hsa-miR-3200-5p	CLIP-seq
MIRT1260192	hsa-miR-362-5p	CLIP-seq
MIRT2076613	hsa-miR-3646	CLIP-seq
MIRT1260214	hsa-miR-4473	CLIP-seq
MIRT2076614	hsa-miR-4522	CLIP-seq
MIRT2076615	hsa-miR-4666-3p	CLIP-seq
MIRT2076616	hsa-miR-4729	CLIP-seq
MIRT2076617	hsa-miR-4760-3p	CLIP-seq
MIRT1260226	hsa-miR-4762-5p	CLIP-seq
MIRT2076618	hsa-miR-4763-5p	CLIP-seq
MIRT2076619	hsa-miR-4774-5p	CLIP-seq
MIRT2076620	hsa-miR-490-3p	CLIP-seq
MIRT1260227	hsa-miR-495	CLIP-seq
MIRT1260228	hsa-miR-500b	CLIP-seq
MIRT1260229	hsa-miR-501-5p	CLIP-seq
MIRT2076621	hsa-miR-548aa	CLIP-seq
MIRT2076622	hsa-miR-579	CLIP-seq
MIRT1260238	hsa-miR-582-5p	CLIP-seq
MIRT2076623	hsa-miR-596	CLIP-seq
MIRT2076624	hsa-miR-627	CLIP-seq
MIRT2076625	hsa-miR-651	CLIP-seq
MIRT2076626	hsa-miR-664	CLIP-seq
MIRT1260166	hsa-let-7a	CLIP-seq
MIRT1260167	hsa-let-7b	CLIP-seq
MIRT1260168	hsa-let-7c	CLIP-seq
MIRT1260169	hsa-let-7d	CLIP-seq
MIRT1260170	hsa-let-7e	CLIP-seq
MIRT1260171	hsa-let-7f	CLIP-seq
MIRT1260172	hsa-let-7g	CLIP-seq
MIRT1260173	hsa-let-7i	CLIP-seq
MIRT2303316	hsa-miR-127-5p	CLIP-seq
MIRT1260176	hsa-miR-1283	CLIP-seq
MIRT1552548	hsa-miR-146a	CLIP-seq
MIRT1552549	hsa-miR-146b-5p	CLIP-seq
MIRT1260179	hsa-miR-197	CLIP-seq
MIRT2303317	hsa-miR-202	CLIP-seq
MIRT2303318	hsa-miR-221	CLIP-seq
MIRT2303319	hsa-miR-222	CLIP-seq
MIRT2303320	hsa-miR-2909	CLIP-seq
MIRT1260182	hsa-miR-3065-5p	CLIP-seq
MIRT1260183	hsa-miR-3120-3p	CLIP-seq
MIRT1260184	hsa-miR-3121-5p	CLIP-seq
MIRT2303321	hsa-miR-3163	CLIP-seq
MIRT2303322	hsa-miR-3183	CLIP-seq
MIRT2076612	hsa-miR-3200-5p	CLIP-seq
MIRT2303323	hsa-miR-324-5p	CLIP-seq
MIRT2303324	hsa-miR-340	CLIP-seq
MIRT2303325	hsa-miR-3612	CLIP-seq
MIRT1260192	hsa-miR-362-5p	CLIP-seq
MIRT2076613	hsa-miR-3646	CLIP-seq
MIRT2303326	hsa-miR-3662	CLIP-seq
MIRT2303327	hsa-miR-3692	CLIP-seq
MIRT1260195	hsa-miR-369-3p	CLIP-seq
MIRT2303328	hsa-miR-371-3p	CLIP-seq
MIRT1260196	hsa-miR-371b-3p	CLIP-seq
MIRT1260197	hsa-miR-374a	CLIP-seq
MIRT1260198	hsa-miR-374b	CLIP-seq
MIRT1260199	hsa-miR-374c	CLIP-seq
MIRT2303329	hsa-miR-3921	CLIP-seq
MIRT2303330	hsa-miR-4264	CLIP-seq
MIRT2303331	hsa-miR-4278	CLIP-seq
MIRT2303332	hsa-miR-4279	CLIP-seq
MIRT2303333	hsa-miR-4315	CLIP-seq
MIRT2303334	hsa-miR-4330	CLIP-seq
MIRT1260212	hsa-miR-4458	CLIP-seq
MIRT1260214	hsa-miR-4473	CLIP-seq
MIRT1260217	hsa-miR-4500	CLIP-seq
MIRT2303335	hsa-miR-4639-3p	CLIP-seq
MIRT2303336	hsa-miR-4649-3p	CLIP-seq
MIRT2303337	hsa-miR-4653-5p	CLIP-seq
MIRT2076615	hsa-miR-4666-3p	CLIP-seq
MIRT2303338	hsa-miR-4671-3p	CLIP-seq
MIRT2303339	hsa-miR-4700-3p	CLIP-seq
MIRT2303340	hsa-miR-4704-3p	CLIP-seq
MIRT2303341	hsa-miR-4716-3p	CLIP-seq
MIRT2303342	hsa-miR-4719	CLIP-seq
MIRT2303343	hsa-miR-4723-3p	CLIP-seq
MIRT2303344	hsa-miR-4723-5p	CLIP-seq
MIRT2303345	hsa-miR-4742-5p	CLIP-seq
MIRT1260226	hsa-miR-4762-5p	CLIP-seq
MIRT2303346	hsa-miR-4775	CLIP-seq
MIRT1260227	hsa-miR-495	CLIP-seq
MIRT1260228	hsa-miR-500b	CLIP-seq
MIRT1260229	hsa-miR-501-5p	CLIP-seq
MIRT1260230	hsa-miR-512-3p	CLIP-seq
MIRT2303347	hsa-miR-515-3p	CLIP-seq
MIRT2303348	hsa-miR-519e	CLIP-seq
MIRT1260231	hsa-miR-520f	CLIP-seq
MIRT1260232	hsa-miR-545	CLIP-seq
MIRT2076621	hsa-miR-548aa	CLIP-seq
MIRT2303349	hsa-miR-548v	CLIP-seq
MIRT1552550	hsa-miR-589	CLIP-seq
MIRT2303350	hsa-miR-593	CLIP-seq
MIRT1260239	hsa-miR-606	CLIP-seq
MIRT2303351	hsa-miR-633	CLIP-seq
MIRT2303352	hsa-miR-650	CLIP-seq
MIRT1260240	hsa-miR-655	CLIP-seq
MIRT2303353	hsa-miR-891b	CLIP-seq
MIRT1260245	hsa-miR-98	CLIP-seq
MIRT1260166	hsa-let-7a	CLIP-seq
MIRT1260167	hsa-let-7b	CLIP-seq
MIRT1260168	hsa-let-7c	CLIP-seq
MIRT1260169	hsa-let-7d	CLIP-seq
MIRT1260170	hsa-let-7e	CLIP-seq
MIRT1260171	hsa-let-7f	CLIP-seq
MIRT1260172	hsa-let-7g	CLIP-seq
MIRT1260173	hsa-let-7i	CLIP-seq
MIRT1260176	hsa-miR-1283	CLIP-seq
MIRT1552547	hsa-miR-144	CLIP-seq
MIRT1552548	hsa-miR-146a	CLIP-seq
MIRT1552549	hsa-miR-146b-5p	CLIP-seq
MIRT1260179	hsa-miR-197	CLIP-seq
MIRT2432253	hsa-miR-338-5p	CLIP-seq
MIRT1260190	hsa-miR-3613-3p	CLIP-seq
MIRT1260191	hsa-miR-3616-5p	CLIP-seq
MIRT1260193	hsa-miR-3647-5p	CLIP-seq
MIRT1260203	hsa-miR-3927	CLIP-seq
MIRT1260204	hsa-miR-3942-3p	CLIP-seq
MIRT1260205	hsa-miR-4257	CLIP-seq
MIRT1260212	hsa-miR-4458	CLIP-seq
MIRT1260217	hsa-miR-4500	CLIP-seq
MIRT1260220	hsa-miR-4670-3p	CLIP-seq
MIRT2303342	hsa-miR-4719	CLIP-seq
MIRT2076621	hsa-miR-548aa	CLIP-seq
MIRT1260235	hsa-miR-573	CLIP-seq
MIRT1260237	hsa-miR-580	CLIP-seq
MIRT1552550	hsa-miR-589	CLIP-seq
MIRT1260245	hsa-miR-98	CLIP-seq
MIRT1260166	hsa-let-7a	CLIP-seq
MIRT1260167	hsa-let-7b	CLIP-seq
MIRT1260168	hsa-let-7c	CLIP-seq
MIRT1260169	hsa-let-7d	CLIP-seq
MIRT1260170	hsa-let-7e	CLIP-seq
MIRT1260171	hsa-let-7f	CLIP-seq
MIRT1260172	hsa-let-7g	CLIP-seq
MIRT1260173	hsa-let-7i	CLIP-seq
MIRT2076608	hsa-miR-1207-3p	CLIP-seq
MIRT2076609	hsa-miR-1258	CLIP-seq
MIRT2076610	hsa-miR-1290	CLIP-seq
MIRT2303317	hsa-miR-202	CLIP-seq
MIRT1260182	hsa-miR-3065-5p	CLIP-seq
MIRT1260184	hsa-miR-3121-5p	CLIP-seq
MIRT2076611	hsa-miR-3159	CLIP-seq
MIRT2076612	hsa-miR-3200-5p	CLIP-seq
MIRT1260188	hsa-miR-3529	CLIP-seq
MIRT1260192	hsa-miR-362-5p	CLIP-seq
MIRT1260194	hsa-miR-3663-5p	CLIP-seq
MIRT2599941	hsa-miR-3671	CLIP-seq
MIRT1260200	hsa-miR-379	CLIP-seq
MIRT1260201	hsa-miR-382	CLIP-seq
MIRT1260208	hsa-miR-431	CLIP-seq
MIRT2303334	hsa-miR-4330	CLIP-seq
MIRT1260210	hsa-miR-4451	CLIP-seq
MIRT1260211	hsa-miR-4453	CLIP-seq
MIRT1260212	hsa-miR-4458	CLIP-seq
MIRT1260214	hsa-miR-4473	CLIP-seq
MIRT1260217	hsa-miR-4500	CLIP-seq
MIRT2599942	hsa-miR-450b-5p	CLIP-seq
MIRT2076614	hsa-miR-4522	CLIP-seq
MIRT1260218	hsa-miR-4538	CLIP-seq
MIRT2303336	hsa-miR-4649-3p	CLIP-seq
MIRT1260219	hsa-miR-4650-3p	CLIP-seq
MIRT2599943	hsa-miR-4708-3p	CLIP-seq
MIRT2303345	hsa-miR-4742-5p	CLIP-seq
MIRT1260226	hsa-miR-4762-5p	CLIP-seq
MIRT2076618	hsa-miR-4763-5p	CLIP-seq
MIRT2599944	hsa-miR-4768-5p	CLIP-seq
MIRT1260227	hsa-miR-495	CLIP-seq
MIRT2599945	hsa-miR-500a	CLIP-seq
MIRT1260228	hsa-miR-500b	CLIP-seq
MIRT1260229	hsa-miR-501-5p	CLIP-seq
MIRT1260230	hsa-miR-512-3p	CLIP-seq
MIRT1260231	hsa-miR-520f	CLIP-seq
MIRT2599946	hsa-miR-582-3p	CLIP-seq
MIRT2076623	hsa-miR-596	CLIP-seq
MIRT1260239	hsa-miR-606	CLIP-seq
MIRT2599947	hsa-miR-607	CLIP-seq
MIRT2076624	hsa-miR-627	CLIP-seq
MIRT2076625	hsa-miR-651	CLIP-seq
MIRT2303353	hsa-miR-891b	CLIP-seq
MIRT1260245	hsa-miR-98	CLIP-seq
MIRT2076608	hsa-miR-1207-3p	CLIP-seq
MIRT2076609	hsa-miR-1258	CLIP-seq
MIRT2076610	hsa-miR-1290	CLIP-seq
MIRT1260182	hsa-miR-3065-5p	CLIP-seq
MIRT1260184	hsa-miR-3121-5p	CLIP-seq
MIRT2076611	hsa-miR-3159	CLIP-seq
MIRT1260192	hsa-miR-362-5p	CLIP-seq
MIRT1260194	hsa-miR-3663-5p	CLIP-seq
MIRT2599941	hsa-miR-3671	CLIP-seq
MIRT1260208	hsa-miR-431	CLIP-seq
MIRT1260211	hsa-miR-4453	CLIP-seq
MIRT1260214	hsa-miR-4473	CLIP-seq
MIRT2599942	hsa-miR-450b-5p	CLIP-seq
MIRT2076614	hsa-miR-4522	CLIP-seq
MIRT1260218	hsa-miR-4538	CLIP-seq
MIRT2599943	hsa-miR-4708-3p	CLIP-seq
MIRT2303345	hsa-miR-4742-5p	CLIP-seq
MIRT1260226	hsa-miR-4762-5p	CLIP-seq
MIRT2076618	hsa-miR-4763-5p	CLIP-seq
MIRT2599944	hsa-miR-4768-5p	CLIP-seq
MIRT1260227	hsa-miR-495	CLIP-seq
MIRT2599945	hsa-miR-500a	CLIP-seq
MIRT1260228	hsa-miR-500b	CLIP-seq
MIRT1260229	hsa-miR-501-5p	CLIP-seq
MIRT1260230	hsa-miR-512-3p	CLIP-seq
MIRT1260231	hsa-miR-520f	CLIP-seq
MIRT2599946	hsa-miR-582-3p	CLIP-seq
MIRT2076623	hsa-miR-596	CLIP-seq
MIRT1260239	hsa-miR-606	CLIP-seq
MIRT2599947	hsa-miR-607	CLIP-seq
MIRT2076624	hsa-miR-627	CLIP-seq
MIRT2076625	hsa-miR-651	CLIP-seq
MIRT2303353	hsa-miR-891b	CLIP-seq

Show/Hide all (1)

Transcription factor	Regulation	Reference
YY1	Activation	18488713

Show/Hide all (29)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	9334209
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IMP	8654390
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	9334209
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	8654390
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	8654390
GO:0003677	Function	DNA binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	NAS	7590293, 8654390
GO:0005515	Function	Protein binding	IPI	25640033
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	11544182
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	NAS	7538672, 7590293
GO:0005654	Component	Nucleoplasm	IDA
GO:0005794	Component	Golgi apparatus	IDA
GO:0006338	Process	Chromatin remodeling	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	NAS	7590293, 8654390
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008168	Function	Methyltransferase activity	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0008270	Function	Zinc ion binding	NAS	7538672
GO:0008340	Process	Determination of adult lifespan	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0032259	Process	Methylation	IEA
GO:0042054	Function	Histone methyltransferase activity	IEA
GO:0043565	Function	Sequence-specific DNA binding	IDA	9334209
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	8654390
GO:0046872	Function	Metal ion binding	IEA
GO:0140949	Function	Histone H3K9 trimethyltransferase activity	IEA

MIM	HGNC	e!Ensembl
601196	9347	ENSG00000116731

Q13029

Protein name

PR domain zinc finger protein 2 (EC 2.1.1.355) (GATA-3-binding protein G3B) (Lysine N-methyltransferase 8) (MTB-ZF) (MTE-binding protein) (PR domain-containing protein 2) (Retinoblastoma protein-interacting zinc finger protein) (Zinc finger protein RIZ)

Protein function

S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme

PDB

2JV0 , 2QPW

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00856	SET	41 → 141	SET domain	Family
PF00096	zf-C2H2	360 → 382	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	390 → 412	Zinc finger, C2H2 type	Domain
PF13912	zf-C2H2_6	482 → 508		Domain
PF13912	zf-C2H2_6	1454 → 1475		Domain

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isofor

Sequence

MNQNTTEPVAATETLAEVPEHVLRGLPEEVRLFPSAVDKTRIGVWATKPILKGKKFGPFV
GDKKKRSQVKNNVYMWEVYYPNLGWMCIDATDPEKGNWLRYVNWACSGEEQNLFPLEINR
AIYYKTLKPIAPGEELLVWYNGEDNPEIAAAIEEERASARSKRSSPKSRKGKKKSQENKN
KGNKIQDIQLKTSEPDFTSANMRDSAEGPKEDEEKPSASALEQPATLQEVASQEVPPELA
TPAPAWEPQPEPDERLEAAACEVNDLGEEEEEEEEEDEEEEEDDDDDELEDEGEEEASMP
NENSVKEPEIRCDEKPEDLLEEPKTTSEETLEDCSEVTPAMQIPRTKEEANGDVFETFMF
PCQHCERKFTTKQGLERHMHIHISTVNHAFKCKYCGKAFGTQINRRRHERRHEAGLKRKP
SQTLQPSEDLADGKASGENVASKDDSSPPSLGPDCLIMNSEKASQDTINSSVVEENGEVK
ELHPCKYCKKVFGTHTNMRRHQRRVHERHLIPKGVRRKGGLEEPQPPAEQAQATQNVYVP
STEPEEEGEADDVYIMDISSNISENLNYYIDGKIQTNNNTSNCDVIEMESASADLYGINC
LLTPVTVEITQNIKTTQVPVTEDLPKEPLGSTNSEAKKRRTASPPALPKIKAETDSDPMV
PSCSLSLPLSISTTEAVSFHKEKSVYLSSKLKQLLQTQDKLTPAGISATEIAKLGPVCVS
APASMLPVTSSRFKRRTSSPPSSPQHSPALRDFGKPSDGKAAWTDAGLTSKKSKLESHSD
SPAWSLSGRDERETVSPPCFDEYKMSKEWTASSAFSSVCNQQPLDLSSGVKQKAEGTGKT
PVQWESVLDLSVHKKHCSDSEGKEFKESHSVQPTCSAVKKRKPTTCMLQKVLLNEYNGID
LPVENPADGTRSPSPCKSLEAQPDPDLGPGSGFPAPTVESTPDVCPSSPALQTPSLSSGQ
LPPLLIPTDPSSPPPCPPVLTVATPPPPLLPTVPLPAPSSSASPHPCPSPLSNATAQSPL
PILSPTVSPSPSPIPPVEPLMSAASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLSA
ISSVVSSGDNLEASLPMISFKQEELENEGLKPREEPQSAAEQDVVVQETFNKNFVCNVCE
SPFLSIKDLTKHLSIHAEEWPFKCEFCVQLFKDKTDLSEHRFLLHGVGNIFVCSVCKKEF
AFLCNLQQHQRDLHPDKVCTHHEFESGTLRPQNFTDPSKAHVEHMQSLPEDPLETSKEEE
ELNDSSEELYTTIKIMASGIKTKDPDVRLGLNQHYPSFKPPPFQYHHRNPMGIGVTATNF
TTHNIPQTFTTAIRCTKCGKGVDNMPELHKHILACASASDKKRYTPKKNPVPLKQTVQPK
NGVVVLDNSGKNAFRRMGQPKRLNFSVELSKMSSNKLKLNALKKKNQLVQKAILQKNKSA
KQKADLKNACESSSHICPYCNREFTYIGSLNKHAAFSCPKKPLSPPKKKVSHSSKKGGHS
SPASSDKNSNSNHRRRTADAEIKMQSMQTPLGKTRARSSGPTQVPLPSSSFRSKQNVKFA
ASVKSKKPSSSSLRNSSPIRMAKITHVEGKKPKAVAKNHSAQLSSKTSRSLHVRVQKSKA
VLQSKSTLASKKRTDRFNIKSRERSGGPVTRSLQLAAAADLSENKREDGSAKQELKDFSY
SLRLASRCSPPAAPYITRQYRKVKAPAAAQFQGPFFKE

Sequence length

1718

Interactions

View interactions

	KEGG
	Lysine degradation Metabolic pathways

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Flexion contracture	Likely pathogenic	rs1570018597	RCV001007819

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Low bone mineral density	Benign	rs2308040	RCV001258317

Show/Hide Text Mining Associations (43)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Brain Neoplasms	Associate	8654390
Breast Neoplasms	Associate	11259086
Carcinogenesis	Associate	10688904, 17103461, 20159667, 25987089
Carcinoma Hepatocellular	Associate	11259086, 17963297, 19385975, 20736025, 32964965
Carcinoma Renal Cell	Inhibit	25987089
Colorectal Neoplasms	Associate	10688904, 11259086, 14760116, 26108676, 37853459
Encephalitis Herpes Simplex	Associate	10688904
Esophageal Squamous Cell Carcinoma	Associate	22363126
Glioma	Associate	16247447, 26690953, 27757741
Leukemia	Associate	12002276
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	19602237, 35421941
Leukemia Myeloid Acute	Inhibit	12472571
Leukemia Prolymphocytic T Cell	Associate	29352181
Leukemia T Cell	Inhibit	12472571
Lung Neoplasms	Associate	24966940
Mesothelioma	Associate	29334678
Mesothelioma Malignant	Associate	29334678
Metabolic Diseases	Associate	29367689
Microsatellite Instability	Associate	14760116, 15309726
Multiple Sclerosis	Associate	28892075
Nasopharyngeal Carcinoma	Associate	21535891
Neoplasm Metastasis	Associate	21369371, 22363126
Neoplasms	Inhibit	10688904, 11259086, 12002276, 14760116, 17052263, 17103461, 17764565, 19602237, 20159667, 20736025, 25131201, 25987089, 26690953, 27757741, 28718376, 29367689, 37853459 View all (2 more)
Neoplasms	Associate	11591891, 12472571, 16475210, 17968429, 21369371, 22363126, 24423864, 25884948, 28892075, 30347759, 8654390
Obesity	Associate	29367689
Ovarian Neoplasms	Associate	16928264
Parkinson Disease	Associate	21469201
Pituitary Neoplasms	Associate	28718376
Polycystic Ovary Syndrome	Associate	32574161
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Stimulate	12472571
Prodromal Symptoms	Associate	17052263
Prolactinoma	Associate	25884948
Prostatic Neoplasms	Associate	17052263, 21369371
Prostatitis	Associate	17052263
Rectal Neoplasms	Associate	24040155
Stomach Neoplasms	Associate	11259086, 15309726, 16475210
Thyroid Neoplasms	Inhibit	17103461
Urinary Bladder Neoplasms	Associate	24577895
Uterine Cervical Neoplasms	Inhibit	20159667
Waldenstrom Macroglobulinemia	Associate	24366360
Wilms Tumor	Associate	8119964, 8142654
X Linked Combined Immunodeficiency Diseases	Stimulate	24441146
Xeroderma Pigmentosum	Associate	7876167

PRDM2 (PR/SET domain 2)