Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	7766
Gene name	Zinc finger protein 223
Gene symbol	ZNF223
Synonyms (NCBI Gene)	-
Chromosome	19
Chromosome location	19q13.31
Summary	This gene encodes a protein containing a Kruppel-associated box domain and multiple zinc finger domains. The function of this protein has yet to be determined. [provided by RefSeq, Mar 2014]

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Show/Hide all (217)

miRTarBase ID	miRNA	Experiments	Reference
MIRT550163	hsa-miR-504-5p	PAR-CLIP	20371350
MIRT550162	hsa-miR-10a-5p	PAR-CLIP	20371350
MIRT550161	hsa-miR-10b-5p	PAR-CLIP	20371350
MIRT550160	hsa-miR-586	PAR-CLIP	20371350
MIRT550159	hsa-miR-126-5p	PAR-CLIP	20371350
MIRT550158	hsa-miR-190a-5p	PAR-CLIP	20371350
MIRT550157	hsa-miR-190b	PAR-CLIP	20371350
MIRT550155	hsa-miR-7848-3p	PAR-CLIP	20371350
MIRT550156	hsa-miR-4795-3p	PAR-CLIP	20371350
MIRT550154	hsa-miR-33a-5p	PAR-CLIP	20371350
MIRT550153	hsa-miR-33b-5p	PAR-CLIP	20371350
MIRT550152	hsa-miR-491-3p	PAR-CLIP	20371350
MIRT550163	hsa-miR-504-5p	PAR-CLIP	20371350
MIRT550162	hsa-miR-10a-5p	PAR-CLIP	20371350
MIRT550161	hsa-miR-10b-5p	PAR-CLIP	20371350
MIRT550160	hsa-miR-586	PAR-CLIP	20371350
MIRT550159	hsa-miR-126-5p	PAR-CLIP	20371350
MIRT550158	hsa-miR-190a-5p	PAR-CLIP	20371350
MIRT550157	hsa-miR-190b	PAR-CLIP	20371350
MIRT550155	hsa-miR-7848-3p	PAR-CLIP	20371350
MIRT550156	hsa-miR-4795-3p	PAR-CLIP	20371350
MIRT550154	hsa-miR-33a-5p	PAR-CLIP	20371350
MIRT550153	hsa-miR-33b-5p	PAR-CLIP	20371350
MIRT550152	hsa-miR-491-3p	PAR-CLIP	20371350
MIRT550163	hsa-miR-504-5p	PAR-CLIP	21572407
MIRT550162	hsa-miR-10a-5p	PAR-CLIP	21572407
MIRT550161	hsa-miR-10b-5p	PAR-CLIP	21572407
MIRT550160	hsa-miR-586	PAR-CLIP	21572407
MIRT550159	hsa-miR-126-5p	PAR-CLIP	21572407
MIRT550158	hsa-miR-190a-5p	PAR-CLIP	21572407
MIRT550157	hsa-miR-190b	PAR-CLIP	21572407
MIRT550155	hsa-miR-7848-3p	PAR-CLIP	21572407
MIRT550156	hsa-miR-4795-3p	PAR-CLIP	21572407
MIRT550154	hsa-miR-33a-5p	PAR-CLIP	21572407
MIRT550153	hsa-miR-33b-5p	PAR-CLIP	21572407
MIRT550152	hsa-miR-491-3p	PAR-CLIP	21572407
MIRT526801	hsa-miR-3121-3p	PAR-CLIP	22012620
MIRT526800	hsa-miR-634	PAR-CLIP	22012620
MIRT526798	hsa-miR-3163	PAR-CLIP	22012620
MIRT526799	hsa-miR-6074	PAR-CLIP	22012620
MIRT526797	hsa-miR-545-3p	PAR-CLIP	22012620
MIRT526796	hsa-miR-4797-5p	PAR-CLIP	22012620
MIRT526795	hsa-miR-95-5p	PAR-CLIP	22012620
MIRT526794	hsa-miR-5003-5p	PAR-CLIP	22012620
MIRT526793	hsa-miR-101-3p	PAR-CLIP	22012620
MIRT526792	hsa-miR-582-5p	PAR-CLIP	22012620
MIRT526791	hsa-miR-585-5p	PAR-CLIP	22012620
MIRT526790	hsa-miR-599	PAR-CLIP	22012620
MIRT512592	hsa-miR-583	PAR-CLIP	23446348
MIRT512591	hsa-miR-4761-3p	PAR-CLIP	23446348
MIRT512590	hsa-miR-371b-5p	PAR-CLIP	23446348
MIRT512589	hsa-miR-373-5p	PAR-CLIP	23446348
MIRT512588	hsa-miR-616-5p	PAR-CLIP	23446348
MIRT512587	hsa-miR-371a-5p	PAR-CLIP	23446348
MIRT512586	hsa-miR-372-5p	PAR-CLIP	23446348
MIRT512585	hsa-miR-3616-3p	PAR-CLIP	23446348
MIRT512584	hsa-miR-5689	PAR-CLIP	23446348
MIRT512583	hsa-miR-3945	PAR-CLIP	23446348
MIRT512582	hsa-miR-513c-5p	PAR-CLIP	23446348
MIRT512581	hsa-miR-514b-5p	PAR-CLIP	23446348
MIRT550163	hsa-miR-504-5p	PAR-CLIP	20371350
MIRT550162	hsa-miR-10a-5p	PAR-CLIP	20371350
MIRT550161	hsa-miR-10b-5p	PAR-CLIP	20371350
MIRT550160	hsa-miR-586	PAR-CLIP	20371350
MIRT550159	hsa-miR-126-5p	PAR-CLIP	20371350
MIRT550158	hsa-miR-190a-5p	PAR-CLIP	20371350
MIRT550157	hsa-miR-190b	PAR-CLIP	20371350
MIRT550155	hsa-miR-7848-3p	PAR-CLIP	20371350
MIRT550156	hsa-miR-4795-3p	PAR-CLIP	20371350
MIRT550154	hsa-miR-33a-5p	PAR-CLIP	20371350
MIRT550153	hsa-miR-33b-5p	PAR-CLIP	20371350
MIRT550152	hsa-miR-491-3p	PAR-CLIP	20371350
MIRT550163	hsa-miR-504-5p	PAR-CLIP	20371350
MIRT550162	hsa-miR-10a-5p	PAR-CLIP	20371350
MIRT550161	hsa-miR-10b-5p	PAR-CLIP	20371350
MIRT550160	hsa-miR-586	PAR-CLIP	20371350
MIRT550159	hsa-miR-126-5p	PAR-CLIP	20371350
MIRT550158	hsa-miR-190a-5p	PAR-CLIP	20371350
MIRT550157	hsa-miR-190b	PAR-CLIP	20371350
MIRT550155	hsa-miR-7848-3p	PAR-CLIP	20371350
MIRT550156	hsa-miR-4795-3p	PAR-CLIP	20371350
MIRT550154	hsa-miR-33a-5p	PAR-CLIP	20371350
MIRT550153	hsa-miR-33b-5p	PAR-CLIP	20371350
MIRT550152	hsa-miR-491-3p	PAR-CLIP	20371350
MIRT550163	hsa-miR-504-5p	PAR-CLIP	21572407
MIRT550162	hsa-miR-10a-5p	PAR-CLIP	21572407
MIRT550161	hsa-miR-10b-5p	PAR-CLIP	21572407
MIRT550160	hsa-miR-586	PAR-CLIP	21572407
MIRT550159	hsa-miR-126-5p	PAR-CLIP	21572407
MIRT550158	hsa-miR-190a-5p	PAR-CLIP	21572407
MIRT550157	hsa-miR-190b	PAR-CLIP	21572407
MIRT550155	hsa-miR-7848-3p	PAR-CLIP	21572407
MIRT550156	hsa-miR-4795-3p	PAR-CLIP	21572407
MIRT550154	hsa-miR-33a-5p	PAR-CLIP	21572407
MIRT550153	hsa-miR-33b-5p	PAR-CLIP	21572407
MIRT550152	hsa-miR-491-3p	PAR-CLIP	21572407
MIRT526801	hsa-miR-3121-3p	PAR-CLIP	22012620
MIRT526800	hsa-miR-634	PAR-CLIP	22012620
MIRT526798	hsa-miR-3163	PAR-CLIP	22012620
MIRT526799	hsa-miR-6074	PAR-CLIP	22012620
MIRT526797	hsa-miR-545-3p	PAR-CLIP	22012620
MIRT526796	hsa-miR-4797-5p	PAR-CLIP	22012620
MIRT526795	hsa-miR-95-5p	PAR-CLIP	22012620
MIRT526794	hsa-miR-5003-5p	PAR-CLIP	22012620
MIRT526793	hsa-miR-101-3p	PAR-CLIP	22012620
MIRT526792	hsa-miR-582-5p	PAR-CLIP	22012620
MIRT526791	hsa-miR-585-5p	PAR-CLIP	22012620
MIRT526790	hsa-miR-599	PAR-CLIP	22012620
MIRT512592	hsa-miR-583	PAR-CLIP	23446348
MIRT512591	hsa-miR-4761-3p	PAR-CLIP	23446348
MIRT512590	hsa-miR-371b-5p	PAR-CLIP	23446348
MIRT512589	hsa-miR-373-5p	PAR-CLIP	23446348
MIRT512588	hsa-miR-616-5p	PAR-CLIP	23446348
MIRT512587	hsa-miR-371a-5p	PAR-CLIP	23446348
MIRT512586	hsa-miR-372-5p	PAR-CLIP	23446348
MIRT512585	hsa-miR-3616-3p	PAR-CLIP	23446348
MIRT512584	hsa-miR-5689	PAR-CLIP	23446348
MIRT512583	hsa-miR-3945	PAR-CLIP	23446348
MIRT512582	hsa-miR-513c-5p	PAR-CLIP	23446348
MIRT512581	hsa-miR-514b-5p	PAR-CLIP	23446348
MIRT1518529	hsa-miR-1206	CLIP-seq
MIRT1518530	hsa-miR-140-5p	CLIP-seq
MIRT1518531	hsa-miR-2052	CLIP-seq
MIRT1518532	hsa-miR-3125	CLIP-seq
MIRT1518533	hsa-miR-3174	CLIP-seq
MIRT1518534	hsa-miR-320a	CLIP-seq
MIRT1518535	hsa-miR-320b	CLIP-seq
MIRT1518536	hsa-miR-320c	CLIP-seq
MIRT1518537	hsa-miR-320d	CLIP-seq
MIRT1518538	hsa-miR-3545-5p	CLIP-seq
MIRT1518539	hsa-miR-3591-5p	CLIP-seq
MIRT1518540	hsa-miR-3916	CLIP-seq
MIRT1518541	hsa-miR-3927	CLIP-seq
MIRT1518542	hsa-miR-3935	CLIP-seq
MIRT1518543	hsa-miR-4255	CLIP-seq
MIRT1518544	hsa-miR-4429	CLIP-seq
MIRT1518545	hsa-miR-4460	CLIP-seq
MIRT1518546	hsa-miR-4775	CLIP-seq
MIRT1518547	hsa-miR-488	CLIP-seq
MIRT1518548	hsa-miR-489	CLIP-seq
MIRT1518549	hsa-miR-513c	CLIP-seq
MIRT1518550	hsa-miR-514	CLIP-seq
MIRT1518551	hsa-miR-514b-3p	CLIP-seq
MIRT1518552	hsa-miR-548k	CLIP-seq
MIRT1518553	hsa-miR-548n	CLIP-seq
MIRT1518554	hsa-miR-552	CLIP-seq
MIRT1518555	hsa-miR-577	CLIP-seq
MIRT1518556	hsa-miR-590-3p	CLIP-seq
MIRT1518557	hsa-miR-595	CLIP-seq
MIRT1518558	hsa-miR-921	CLIP-seq
MIRT2376018	hsa-miR-103a	CLIP-seq
MIRT2376019	hsa-miR-107	CLIP-seq
MIRT2376020	hsa-miR-1182	CLIP-seq
MIRT2376021	hsa-miR-1184	CLIP-seq
MIRT2376022	hsa-miR-1205	CLIP-seq
MIRT2376023	hsa-miR-1270	CLIP-seq
MIRT2376024	hsa-miR-129-5p	CLIP-seq
MIRT2376025	hsa-miR-146b-3p	CLIP-seq
MIRT2376026	hsa-miR-3064-5p	CLIP-seq
MIRT2376027	hsa-miR-3157-3p	CLIP-seq
MIRT2376028	hsa-miR-3158-5p	CLIP-seq
MIRT2376029	hsa-miR-3173-5p	CLIP-seq
MIRT2376030	hsa-miR-3664-5p	CLIP-seq
MIRT2376031	hsa-miR-4423-5p	CLIP-seq
MIRT2376032	hsa-miR-4531	CLIP-seq
MIRT2376033	hsa-miR-4639-3p	CLIP-seq
MIRT2376034	hsa-miR-544	CLIP-seq
MIRT2376035	hsa-miR-548m	CLIP-seq
MIRT2376036	hsa-miR-620	CLIP-seq
MIRT2376037	hsa-miR-874	CLIP-seq
MIRT1518529	hsa-miR-1206	CLIP-seq
MIRT1518530	hsa-miR-140-5p	CLIP-seq
MIRT2668496	hsa-miR-1976	CLIP-seq
MIRT1518531	hsa-miR-2052	CLIP-seq
MIRT2668497	hsa-miR-2110	CLIP-seq
MIRT2668498	hsa-miR-3140-5p	CLIP-seq
MIRT1518538	hsa-miR-3545-5p	CLIP-seq
MIRT1518539	hsa-miR-3591-5p	CLIP-seq
MIRT2668499	hsa-miR-3667-5p	CLIP-seq
MIRT2668500	hsa-miR-3909	CLIP-seq
MIRT1518543	hsa-miR-4255	CLIP-seq
MIRT2668501	hsa-miR-4271	CLIP-seq
MIRT2668502	hsa-miR-4421	CLIP-seq
MIRT2668503	hsa-miR-4427	CLIP-seq
MIRT1518545	hsa-miR-4460	CLIP-seq
MIRT2668504	hsa-miR-4637	CLIP-seq
MIRT2668505	hsa-miR-4705	CLIP-seq
MIRT2668506	hsa-miR-4717-3p	CLIP-seq
MIRT2668507	hsa-miR-4725-3p	CLIP-seq
MIRT1518547	hsa-miR-488	CLIP-seq
MIRT1518548	hsa-miR-489	CLIP-seq
MIRT2668508	hsa-miR-494	CLIP-seq
MIRT2668509	hsa-miR-495	CLIP-seq
MIRT1518550	hsa-miR-514	CLIP-seq
MIRT1518551	hsa-miR-514b-3p	CLIP-seq
MIRT2668510	hsa-miR-548g	CLIP-seq
MIRT1518557	hsa-miR-595	CLIP-seq
MIRT1518529	hsa-miR-1206	CLIP-seq
MIRT1518530	hsa-miR-140-5p	CLIP-seq
MIRT1518531	hsa-miR-2052	CLIP-seq
MIRT2668497	hsa-miR-2110	CLIP-seq
MIRT1518538	hsa-miR-3545-5p	CLIP-seq
MIRT1518539	hsa-miR-3591-5p	CLIP-seq
MIRT2668500	hsa-miR-3909	CLIP-seq
MIRT1518543	hsa-miR-4255	CLIP-seq
MIRT2668501	hsa-miR-4271	CLIP-seq
MIRT1518545	hsa-miR-4460	CLIP-seq
MIRT2668504	hsa-miR-4637	CLIP-seq
MIRT2668505	hsa-miR-4705	CLIP-seq
MIRT2668506	hsa-miR-4717-3p	CLIP-seq
MIRT2668507	hsa-miR-4725-3p	CLIP-seq
MIRT1518547	hsa-miR-488	CLIP-seq
MIRT1518548	hsa-miR-489	CLIP-seq
MIRT2668508	hsa-miR-494	CLIP-seq
MIRT1518550	hsa-miR-514	CLIP-seq
MIRT1518551	hsa-miR-514b-3p	CLIP-seq
MIRT2668510	hsa-miR-548g	CLIP-seq

Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0003677	Function	DNA binding	NAS	10449920
GO:0003700	Function	DNA-binding transcription factor activity	NAS	34673265
GO:0005515	Function	Protein binding	IPI	25416956, 31515488, 32296183
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0045892	Process	Negative regulation of DNA-templated transcription	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
HGNC	N/A	HGNC

Q9UK11

Protein name

Zinc finger protein 223

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	7 → 48	KRAB box	Family
PF00096	zf-C2H2	176 → 198	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	204 → 226	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	260 → 282	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	344 → 366	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	372 → 394	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	400 → 422	Zinc finger, C2H2 type	Domain

Sequence

MTMSKEAVTFKDVAVVFTEEELGLLDLAQRKLYRDVMLENFRNLLSVGHQPFHRDTFHFL
REEKFWMMDIATQREGNSGGKIQPEMKTFPEAGPHEGWSCQQIWEEIASDLTRPQDSTIK
SSQFFEQGDAHSQVEEGLSIMHTGQKPSNCGKCKQSFSDMSIFDLPQQIRSAEKSHSCDE
CGKSFCYISALHIHQRVHLGEKLFKCDVCGKEFSQSLHLQTHQRVHTGEKPFKCEQCGRG
FRCRSALTVHCKLHMGEKHYNCEACGRAFIHDFQLQKHQRIHTGEKPFKCEICSVSFRLR
SSLNRHCVVHTGKKPNSTGEYGKGFIRRLDLCKHQTIHTGEKPYNCKECGKSFRRSSYLL
IHQRVHTGEKPYKCDKCGKSYITKSGLDLHHRAHTGERPYNCDDCGKSFRQASSILNHKR
LHCRKKPFKCEDCGKKLVYRSYRKDQQKNHSGENPSKCEDCGKRYKRRLNLDIILSLFLN
DT

Sequence length

482

Interactions

View interactions

	Reactome
			Generic Transcription Pathway

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
GASTROESOPHAGEAL REFLUX DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

ZNF223 (zinc finger protein 223)