Gene Gene information from NCBI Gene database.
Entrez ID 7753
Gene name Zinc finger protein 202
Gene symbol ZNF202
Synonyms (NCBI Gene)
ZKSCAN10ZSCAN42
Chromosome 11
Chromosome location 11q24.1
miRNA miRNA information provided by mirtarbase database.
240
miRTarBase ID miRNA Experiments Reference
MIRT020106 hsa-miR-130b-3p Sequencing 20371350
MIRT027505 hsa-miR-98-5p Microarray 19088304
MIRT027951 hsa-miR-93-5p Sequencing 20371350
MIRT041854 hsa-miR-484 CLASH 23622248
MIRT027951 hsa-miR-93-5p PAR-CLIP 20371350
Transcription factors Transcription factors information provided by TRRUST V2 database.
1
Transcription factor Regulation Reference
SCAND1 Unknown 12444922
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
19
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IDA 10748193
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA 10748193
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0001227 Function DNA-binding transcription repressor activity, RNA polymerase II-specific IDA 10748193
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
603430 12994 ENSG00000166261
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O95125
Protein name Zinc finger protein 202 (Zinc finger protein with KRAB and SCAN domains 10)
Protein function Transcriptional repressor that binds to elements found predominantly in genes that participate in lipid metabolism. Among its targets are structural components of lipoprotein particles (apolipoproteins AIV, CIII, and E), enzymes involved in lipi
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02023 SCAN 42 131 SCAN domain Domain
PF01352 KRAB 236 277 KRAB box Family
PF00096 zf-C2H2 397 419 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 425 447 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 481 503 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 509 531 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 565 587 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 593 615 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 621 643 Zinc finger, C2H2 type Domain
Tissue specificity TISSUE SPECIFICITY: Highly expressed in testis. Also expressed in breast carcinoma cell lines.
Sequence
MATAVEPEDQDLWEEEGILMVKLEDDFTCRPESVLQRDDPVLETSHQNFRRFRYQEAASP
REALIRLRELCHQWLRPERRTKEQILELLVLEQFLTVLPGELQSWVRGQRPESGEEAVTL
VEGLQKQPRRP
RRWVTVHVHGQEVLSEETVHLGVEPESPNELQDPVQSSTPEQSPEETTQ
SPDLGAPAEQRPHQEEELQTLQESEVPVPEDPDLPAERSSGDSEMVALLTALSQGLVTFK
DVAVCFSQDQWSDLDPTQKEFYGEYVLEEDCGIVVSL
SFPIPRPDEISQVREEEPWVPDI
QEPQETQEPEILSFTYTGDRSKDEEECLEQEDLSLEDIHRPVLGEPEIHQTPDWEIVFED
NPGRLNERRFGTNISQVNSFVNLRETTPVHPLLGRHHDCSVCGKSFTCNSHLVRHLRTHT
GEKPYKCMECGKSYTRSSHLARHQKVHKMNAPYKYPLNRKNLEETSPVTQAERTPSVEKP
YRCDDCGKHFRWTSDLVRHQRTHTGEKPFFCTICGKSFSQKSVLTTHQRIHLGGKPYLCG
ECGEDFSEHRRYLAHRKTHAAEELYLCSECGRCFTHSAAFAKHLRGHASVRPCRCNECGK
SFSRRDHLVRHQRTH
TGEKPFTCPTCGKSFSRGYHLIRHQRTHSEKTS
Sequence length 648
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
2
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
PROSTATE CANCER GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
PROSTATE CARCINOMA GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Atherosclerosis Associate 18652945
★☆☆☆☆
Found in Text Mining only
Drug Related Side Effects and Adverse Reactions Associate 19875103
★☆☆☆☆
Found in Text Mining only
Dyslipidemias Associate 10748193
★☆☆☆☆
Found in Text Mining only
Hypoalphalipoproteinemias Associate 11279031
★☆☆☆☆
Found in Text Mining only
Muscular Dystrophies Limb Girdle Associate 22419172
★☆☆☆☆
Found in Text Mining only
Myocardial Ischemia Associate 18652945
★☆☆☆☆
Found in Text Mining only
Parkinson Disease Secondary Associate 19875103
★☆☆☆☆
Found in Text Mining only
Pelizaeus Merzbacher Disease Associate 19875103
★☆☆☆☆
Found in Text Mining only
Vascular Diseases Associate 10748193
★☆☆☆☆
Found in Text Mining only