Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	7733
Gene name	Zinc finger protein 180
Gene symbol	ZNF180
Synonyms (NCBI Gene)	HHZ168
Chromosome	19
Chromosome location	19q13.31
Summary	Zinc finger proteins have been shown to interact with nucleic acids and to have diverse functions. The zinc finger domain is a conserved amino acid sequence motif containing 2 specifically positioned cysteines and 2 histidines that are involved in coordin

201

Show/Hide all (201)

miRTarBase ID	miRNA	Experiments	Reference
MIRT028027	hsa-miR-93-5p	Sequencing	20371350
MIRT503972	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT503971	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT503970	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT503969	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT503968	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT503967	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT503966	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT503965	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT503964	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT028027	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT503963	hsa-miR-651-3p	PAR-CLIP	21572407
MIRT503962	hsa-miR-126-5p	PAR-CLIP	21572407
MIRT503960	hsa-miR-6830-5p	PAR-CLIP	21572407
MIRT503961	hsa-miR-16-1-3p	PAR-CLIP	21572407
MIRT503958	hsa-miR-4772-3p	PAR-CLIP	21572407
MIRT503959	hsa-miR-2276-3p	PAR-CLIP	21572407
MIRT503957	hsa-miR-4708-3p	PAR-CLIP	21572407
MIRT503956	hsa-miR-6124	PAR-CLIP	21572407
MIRT503955	hsa-miR-4795-3p	PAR-CLIP	21572407
MIRT503954	hsa-miR-376a-3p	PAR-CLIP	21572407
MIRT503953	hsa-miR-376b-3p	PAR-CLIP	21572407
MIRT503952	hsa-miR-544a	PAR-CLIP	21572407
MIRT527679	hsa-miR-6738-3p	PAR-CLIP	21572407
MIRT503951	hsa-miR-335-3p	PAR-CLIP	21572407
MIRT503972	hsa-miR-548az-5p	PAR-CLIP	22012620
MIRT503971	hsa-miR-548t-5p	PAR-CLIP	22012620
MIRT503970	hsa-miR-106a-5p	PAR-CLIP	22012620
MIRT503969	hsa-miR-106b-5p	PAR-CLIP	22012620
MIRT503968	hsa-miR-17-5p	PAR-CLIP	22012620
MIRT503967	hsa-miR-20a-5p	PAR-CLIP	22012620
MIRT503966	hsa-miR-20b-5p	PAR-CLIP	22012620
MIRT503965	hsa-miR-519d-3p	PAR-CLIP	22012620
MIRT503964	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT028027	hsa-miR-93-5p	PAR-CLIP	22012620
MIRT503963	hsa-miR-651-3p	PAR-CLIP	22012620
MIRT503962	hsa-miR-126-5p	PAR-CLIP	22012620
MIRT503960	hsa-miR-6830-5p	PAR-CLIP	22012620
MIRT503961	hsa-miR-16-1-3p	PAR-CLIP	22012620
MIRT503958	hsa-miR-4772-3p	PAR-CLIP	22012620
MIRT503959	hsa-miR-2276-3p	PAR-CLIP	22012620
MIRT503957	hsa-miR-4708-3p	PAR-CLIP	22012620
MIRT503956	hsa-miR-6124	PAR-CLIP	22012620
MIRT503955	hsa-miR-4795-3p	PAR-CLIP	22012620
MIRT503954	hsa-miR-376a-3p	PAR-CLIP	22012620
MIRT503953	hsa-miR-376b-3p	PAR-CLIP	22012620
MIRT503952	hsa-miR-544a	PAR-CLIP	22012620
MIRT527679	hsa-miR-6738-3p	PAR-CLIP	22012620
MIRT503951	hsa-miR-335-3p	PAR-CLIP	22012620
MIRT503972	hsa-miR-548az-5p	PAR-CLIP	23446348
MIRT503971	hsa-miR-548t-5p	PAR-CLIP	23446348
MIRT503970	hsa-miR-106a-5p	PAR-CLIP	23446348
MIRT503969	hsa-miR-106b-5p	PAR-CLIP	23446348
MIRT503968	hsa-miR-17-5p	PAR-CLIP	23446348
MIRT503967	hsa-miR-20a-5p	PAR-CLIP	23446348
MIRT503966	hsa-miR-20b-5p	PAR-CLIP	23446348
MIRT503965	hsa-miR-519d-3p	PAR-CLIP	23446348
MIRT503964	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT028027	hsa-miR-93-5p	PAR-CLIP	23446348
MIRT503963	hsa-miR-651-3p	PAR-CLIP	23446348
MIRT503962	hsa-miR-126-5p	PAR-CLIP	23446348
MIRT503960	hsa-miR-6830-5p	PAR-CLIP	23446348
MIRT503961	hsa-miR-16-1-3p	PAR-CLIP	23446348
MIRT503958	hsa-miR-4772-3p	PAR-CLIP	23446348
MIRT503959	hsa-miR-2276-3p	PAR-CLIP	23446348
MIRT503957	hsa-miR-4708-3p	PAR-CLIP	23446348
MIRT503956	hsa-miR-6124	PAR-CLIP	23446348
MIRT503955	hsa-miR-4795-3p	PAR-CLIP	23446348
MIRT503954	hsa-miR-376a-3p	PAR-CLIP	23446348
MIRT503953	hsa-miR-376b-3p	PAR-CLIP	23446348
MIRT503952	hsa-miR-544a	PAR-CLIP	23446348
MIRT503951	hsa-miR-335-3p	PAR-CLIP	23446348
MIRT439222	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT439221	ebv-miR-BART7-3p	HITS-CLIP	22473208
MIRT439222	ebv-miR-BART10-3p	HITS-CLIP	22473208
MIRT439221	ebv-miR-BART7-3p	HITS-CLIP	22473208
MIRT503972	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT503971	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT503970	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT503969	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT503968	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT503967	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT503966	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT503965	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT503964	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT028027	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT503963	hsa-miR-651-3p	PAR-CLIP	21572407
MIRT503962	hsa-miR-126-5p	PAR-CLIP	21572407
MIRT503960	hsa-miR-6830-5p	PAR-CLIP	21572407
MIRT503961	hsa-miR-16-1-3p	PAR-CLIP	21572407
MIRT503958	hsa-miR-4772-3p	PAR-CLIP	21572407
MIRT503959	hsa-miR-2276-3p	PAR-CLIP	21572407
MIRT503957	hsa-miR-4708-3p	PAR-CLIP	21572407
MIRT503956	hsa-miR-6124	PAR-CLIP	21572407
MIRT503955	hsa-miR-4795-3p	PAR-CLIP	21572407
MIRT503954	hsa-miR-376a-3p	PAR-CLIP	21572407
MIRT503953	hsa-miR-376b-3p	PAR-CLIP	21572407
MIRT503952	hsa-miR-544a	PAR-CLIP	21572407
MIRT527679	hsa-miR-6738-3p	PAR-CLIP	21572407
MIRT503951	hsa-miR-335-3p	PAR-CLIP	21572407
MIRT503972	hsa-miR-548az-5p	PAR-CLIP	22012620
MIRT503971	hsa-miR-548t-5p	PAR-CLIP	22012620
MIRT503970	hsa-miR-106a-5p	PAR-CLIP	22012620
MIRT503969	hsa-miR-106b-5p	PAR-CLIP	22012620
MIRT503968	hsa-miR-17-5p	PAR-CLIP	22012620
MIRT503967	hsa-miR-20a-5p	PAR-CLIP	22012620
MIRT503966	hsa-miR-20b-5p	PAR-CLIP	22012620
MIRT503965	hsa-miR-519d-3p	PAR-CLIP	22012620
MIRT503964	hsa-miR-526b-3p	PAR-CLIP	22012620
MIRT028027	hsa-miR-93-5p	PAR-CLIP	22012620
MIRT503963	hsa-miR-651-3p	PAR-CLIP	22012620
MIRT503962	hsa-miR-126-5p	PAR-CLIP	22012620
MIRT503960	hsa-miR-6830-5p	PAR-CLIP	22012620
MIRT503961	hsa-miR-16-1-3p	PAR-CLIP	22012620
MIRT503958	hsa-miR-4772-3p	PAR-CLIP	22012620
MIRT503959	hsa-miR-2276-3p	PAR-CLIP	22012620
MIRT503957	hsa-miR-4708-3p	PAR-CLIP	22012620
MIRT503956	hsa-miR-6124	PAR-CLIP	22012620
MIRT503955	hsa-miR-4795-3p	PAR-CLIP	22012620
MIRT503954	hsa-miR-376a-3p	PAR-CLIP	22012620
MIRT503953	hsa-miR-376b-3p	PAR-CLIP	22012620
MIRT503952	hsa-miR-544a	PAR-CLIP	22012620
MIRT527679	hsa-miR-6738-3p	PAR-CLIP	22012620
MIRT503951	hsa-miR-335-3p	PAR-CLIP	22012620
MIRT503972	hsa-miR-548az-5p	PAR-CLIP	23446348
MIRT503971	hsa-miR-548t-5p	PAR-CLIP	23446348
MIRT503970	hsa-miR-106a-5p	PAR-CLIP	23446348
MIRT503969	hsa-miR-106b-5p	PAR-CLIP	23446348
MIRT503968	hsa-miR-17-5p	PAR-CLIP	23446348
MIRT503967	hsa-miR-20a-5p	PAR-CLIP	23446348
MIRT503966	hsa-miR-20b-5p	PAR-CLIP	23446348
MIRT503965	hsa-miR-519d-3p	PAR-CLIP	23446348
MIRT503964	hsa-miR-526b-3p	PAR-CLIP	23446348
MIRT028027	hsa-miR-93-5p	PAR-CLIP	23446348
MIRT503963	hsa-miR-651-3p	PAR-CLIP	23446348
MIRT503962	hsa-miR-126-5p	PAR-CLIP	23446348
MIRT503960	hsa-miR-6830-5p	PAR-CLIP	23446348
MIRT503961	hsa-miR-16-1-3p	PAR-CLIP	23446348
MIRT503958	hsa-miR-4772-3p	PAR-CLIP	23446348
MIRT503959	hsa-miR-2276-3p	PAR-CLIP	23446348
MIRT503957	hsa-miR-4708-3p	PAR-CLIP	23446348
MIRT503956	hsa-miR-6124	PAR-CLIP	23446348
MIRT503955	hsa-miR-4795-3p	PAR-CLIP	23446348
MIRT503954	hsa-miR-376a-3p	PAR-CLIP	23446348
MIRT503953	hsa-miR-376b-3p	PAR-CLIP	23446348
MIRT503952	hsa-miR-544a	PAR-CLIP	23446348
MIRT503951	hsa-miR-335-3p	PAR-CLIP	23446348
MIRT1517151	hsa-miR-106a	CLIP-seq
MIRT1517152	hsa-miR-106b	CLIP-seq
MIRT1517153	hsa-miR-17	CLIP-seq
MIRT1517154	hsa-miR-181a	CLIP-seq
MIRT1517155	hsa-miR-181b	CLIP-seq
MIRT1517156	hsa-miR-181c	CLIP-seq
MIRT1517157	hsa-miR-181d	CLIP-seq
MIRT1517158	hsa-miR-186	CLIP-seq
MIRT1517159	hsa-miR-20a	CLIP-seq
MIRT1517160	hsa-miR-20b	CLIP-seq
MIRT1517161	hsa-miR-3136-3p	CLIP-seq
MIRT1517162	hsa-miR-3143	CLIP-seq
MIRT1517163	hsa-miR-376a	CLIP-seq
MIRT1517164	hsa-miR-376b	CLIP-seq
MIRT1517165	hsa-miR-4251	CLIP-seq
MIRT1517166	hsa-miR-4262	CLIP-seq
MIRT1517167	hsa-miR-4476	CLIP-seq
MIRT1517168	hsa-miR-4493	CLIP-seq
MIRT1517169	hsa-miR-4803	CLIP-seq
MIRT1517170	hsa-miR-519d	CLIP-seq
MIRT1517171	hsa-miR-539	CLIP-seq
MIRT1517172	hsa-miR-543	CLIP-seq
MIRT1517173	hsa-miR-548g	CLIP-seq
MIRT1517174	hsa-miR-568	CLIP-seq
MIRT1517175	hsa-miR-93	CLIP-seq
MIRT2156135	hsa-miR-1260	CLIP-seq
MIRT2156136	hsa-miR-1260b	CLIP-seq
MIRT2156137	hsa-miR-188-3p	CLIP-seq
MIRT2156138	hsa-miR-3120-3p	CLIP-seq
MIRT2156139	hsa-miR-3156-3p	CLIP-seq
MIRT2156140	hsa-miR-3168	CLIP-seq
MIRT2156141	hsa-miR-3652	CLIP-seq
MIRT2156142	hsa-miR-4430	CLIP-seq
MIRT2156143	hsa-miR-4446-3p	CLIP-seq
MIRT2156144	hsa-miR-4446-5p	CLIP-seq
MIRT2156145	hsa-miR-4492	CLIP-seq
MIRT2156146	hsa-miR-4498	CLIP-seq
MIRT2156147	hsa-miR-4719	CLIP-seq
MIRT2156148	hsa-miR-4721	CLIP-seq
MIRT2156149	hsa-miR-4731-3p	CLIP-seq
MIRT2156150	hsa-miR-4801	CLIP-seq
MIRT2156151	hsa-miR-762	CLIP-seq
MIRT2156137	hsa-miR-188-3p	CLIP-seq
MIRT2156140	hsa-miR-3168	CLIP-seq
MIRT2375706	hsa-miR-34a	CLIP-seq
MIRT2375707	hsa-miR-34c-5p	CLIP-seq
MIRT2375708	hsa-miR-449a	CLIP-seq
MIRT2375709	hsa-miR-449b	CLIP-seq
MIRT2375710	hsa-miR-4715-5p	CLIP-seq
MIRT2156147	hsa-miR-4719	CLIP-seq
MIRT2156149	hsa-miR-4731-3p	CLIP-seq
MIRT2375711	hsa-miR-4799-5p	CLIP-seq
MIRT2156150	hsa-miR-4801	CLIP-seq
MIRT2375712	hsa-miR-576-5p	CLIP-seq

Show/Hide all (10)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 31413325, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
606740	12970	ENSG00000167384

Q9UJW8

Protein name

Zinc finger protein 180 (HHZ168)

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	71 → 112	KRAB box	Family
PF00096	zf-C2H2	353 → 375	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	381 → 403	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	409 → 431	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	437 → 459	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	465 → 487	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	493 → 515	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	521 → 543	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	549 → 571	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	577 → 599	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	605 → 627	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	633 → 655	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	661 → 683	Zinc finger, C2H2 type	Domain

Sequence

MRACAGSTREAGSGAQDLSTLLCLEESMEEQDEKPPEPPKACAQDSFLPQEIIIKVEGED
TGSLTIPSQEGVNFKIVTVDFTREEQGTWNPAQRTLDRDVILENHRDLVSWDLATAVGKK
DSTSKQRIFDEEPANGVKIERFTRDDPWLSSCEEVDDCKDQLEKQQEKQEILLQEVAFTQ
RKAVIHERVCKSDETGEKSGLNSSLFSSPVIPIRNHFHKHVSHAKKWHLNAAVNSHQKIN
ENETLYENNECGKPPQSIHLIQFTRTQTKDKCYGFSDRIQSFCHGTPLHIHEKIHGGGKT
FDFKECGQVLNPKISHNEQQRIPFEESQYKCSETSHSSSLTQNMRNNSEEKPFECNQCGK
SFSWSSHLVAHQRTHTGEKPYECSECGKSFSRSSHLVSHQRTHTGEKPYRCNQCGKSFSQ
SYVLVVHQRTHTGEKPYECNQCGKSFRQSYKLIAHQRTHTGEKPYECNQCGKSFIQSYKL
IAHQRIHTGEKPYECNQCGKSFSQSYKLVAHQRTHTGEKPFECNQCGKSFSWSSQLVAHQ
RTHTGEKPYECSECGKSFNRSSHLVMHQRIHTGEKPYECNQCGKSFSQSYVLVVHQRTHT
GEKPYECSQCGKSFRQSSCLTQHQRTHTGEKPFECNQCGKTFSLSARLIVHQRTHTGEKP
FTCIQCGKAFINSYKLIRHQATHTEEKLYECN

Sequence length

692

Interactions

View interactions

	Reactome
			Generic Transcription Pathway

Evidence Score: ★☆☆☆☆ Gene-disease association found in Text Mining only ★★☆☆☆ Found in Text Mining and Unknown/Other Associations ★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Show/Hide Unknown Diseases (2)

Phenotype Name	Clinical Significance	Source	Evidence Score
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
ALZHEIMER DISEASE	—	GWAS catalog	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations
Gastric cancer	Uncertain significance	ClinVar	★★★★★ ★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References	Evidence Score
Associations from Text MiningDisease associations identified through Pubtator
Melanoma	Associate	33619278	★★★★★ ★☆☆☆☆ Found in Text Mining only

ZNF180 (zinc finger protein 180)