Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	7728
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc finger protein 175
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZNF175
Synonyms (NCBI Gene) Gene synonyms aliases	OTK18
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19q13.41

Show/Hide all(243)

miRTarBase ID	miRNA	Experiments	Reference
MIRT004203	hsa-miR-197-3p	Microarray	16822819
MIRT016079	hsa-miR-374b-5p	Sequencing	20371350
MIRT017746	hsa-miR-335-5p	Microarray	18185580
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT621072	hsa-miR-629-5p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT649714	hsa-miR-7161-3p	HITS-CLIP	23824327
MIRT649713	hsa-miR-3168	HITS-CLIP	23824327
MIRT649712	hsa-miR-148b-5p	HITS-CLIP	23824327
MIRT649711	hsa-miR-6874-3p	HITS-CLIP	23824327
MIRT649710	hsa-miR-5584-3p	HITS-CLIP	23824327
MIRT649709	hsa-miR-146a-3p	HITS-CLIP	23824327
MIRT649708	hsa-miR-301a-5p	HITS-CLIP	23824327
MIRT649707	hsa-miR-301b-5p	HITS-CLIP	23824327
MIRT649706	hsa-miR-3921	HITS-CLIP	23824327
MIRT649705	hsa-miR-4653-5p	HITS-CLIP	23824327
MIRT649704	hsa-miR-1199-5p	HITS-CLIP	23824327
MIRT649703	hsa-miR-6751-3p	HITS-CLIP	23824327
MIRT649702	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT649701	hsa-miR-2117	HITS-CLIP	23824327
MIRT649700	hsa-miR-513a-5p	HITS-CLIP	23824327
MIRT649699	hsa-miR-27a-3p	HITS-CLIP	23824327
MIRT649698	hsa-miR-27b-3p	HITS-CLIP	23824327
MIRT649697	hsa-miR-3191-5p	HITS-CLIP	23824327
MIRT649696	hsa-miR-4303	HITS-CLIP	23824327
MIRT649695	hsa-miR-6807-5p	HITS-CLIP	23824327
MIRT649694	hsa-miR-5096	HITS-CLIP	23824327
MIRT649693	hsa-miR-5195-3p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT621072	hsa-miR-629-5p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT621072	hsa-miR-629-5p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT621072	hsa-miR-629-5p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT649714	hsa-miR-7161-3p	HITS-CLIP	23824327
MIRT649713	hsa-miR-3168	HITS-CLIP	23824327
MIRT649712	hsa-miR-148b-5p	HITS-CLIP	23824327
MIRT649711	hsa-miR-6874-3p	HITS-CLIP	23824327
MIRT649710	hsa-miR-5584-3p	HITS-CLIP	23824327
MIRT649709	hsa-miR-146a-3p	HITS-CLIP	23824327
MIRT649708	hsa-miR-301a-5p	HITS-CLIP	23824327
MIRT649707	hsa-miR-301b-5p	HITS-CLIP	23824327
MIRT649706	hsa-miR-3921	HITS-CLIP	23824327
MIRT649705	hsa-miR-4653-5p	HITS-CLIP	23824327
MIRT649704	hsa-miR-1199-5p	HITS-CLIP	23824327
MIRT649703	hsa-miR-6751-3p	HITS-CLIP	23824327
MIRT649702	hsa-miR-627-3p	HITS-CLIP	23824327
MIRT649701	hsa-miR-2117	HITS-CLIP	23824327
MIRT649700	hsa-miR-513a-5p	HITS-CLIP	23824327
MIRT649699	hsa-miR-27a-3p	HITS-CLIP	23824327
MIRT649698	hsa-miR-27b-3p	HITS-CLIP	23824327
MIRT649697	hsa-miR-3191-5p	HITS-CLIP	23824327
MIRT649696	hsa-miR-4303	HITS-CLIP	23824327
MIRT649695	hsa-miR-6807-5p	HITS-CLIP	23824327
MIRT649694	hsa-miR-5096	HITS-CLIP	23824327
MIRT649693	hsa-miR-5195-3p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT621072	hsa-miR-629-5p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT621072	hsa-miR-629-5p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT611980	hsa-miR-8485	HITS-CLIP	23824327
MIRT611979	hsa-miR-603	HITS-CLIP	23824327
MIRT611978	hsa-miR-1228-3p	HITS-CLIP	23824327
MIRT611977	hsa-miR-216b-3p	HITS-CLIP	23824327
MIRT611976	hsa-miR-342-3p	HITS-CLIP	23824327
MIRT611975	hsa-miR-1229-3p	HITS-CLIP	23824327
MIRT611974	hsa-miR-302c-5p	HITS-CLIP	23824327
MIRT1517126	hsa-miR-2054	CLIP-seq
MIRT1517127	hsa-miR-3200-5p	CLIP-seq
MIRT1517128	hsa-miR-3607-3p	CLIP-seq
MIRT1517129	hsa-miR-3686	CLIP-seq
MIRT1517130	hsa-miR-4517	CLIP-seq
MIRT1517131	hsa-miR-4698	CLIP-seq
MIRT1517132	hsa-miR-4762-3p	CLIP-seq
MIRT1517133	hsa-miR-4766-5p	CLIP-seq
MIRT1517134	hsa-miR-548c-3p	CLIP-seq
MIRT1517135	hsa-miR-574-3p	CLIP-seq
MIRT2156130	hsa-miR-302f	CLIP-seq
MIRT2156131	hsa-miR-3157-3p	CLIP-seq
MIRT1517128	hsa-miR-3607-3p	CLIP-seq
MIRT1517129	hsa-miR-3686	CLIP-seq
MIRT2156132	hsa-miR-4290	CLIP-seq
MIRT2156133	hsa-miR-4452	CLIP-seq
MIRT1517135	hsa-miR-574-3p	CLIP-seq
MIRT2156134	hsa-miR-874	CLIP-seq
MIRT2375685	hsa-miR-1271	CLIP-seq
MIRT2375686	hsa-miR-185	CLIP-seq
MIRT2375687	hsa-miR-216a	CLIP-seq
MIRT2375688	hsa-miR-2467-5p	CLIP-seq
MIRT2156130	hsa-miR-302f	CLIP-seq
MIRT2375689	hsa-miR-30a	CLIP-seq
MIRT2375690	hsa-miR-30b	CLIP-seq
MIRT2375691	hsa-miR-30c	CLIP-seq
MIRT2375692	hsa-miR-30d	CLIP-seq
MIRT2375693	hsa-miR-30e	CLIP-seq
MIRT1517128	hsa-miR-3607-3p	CLIP-seq
MIRT1517129	hsa-miR-3686	CLIP-seq
MIRT2375694	hsa-miR-4284	CLIP-seq
MIRT2375695	hsa-miR-4306	CLIP-seq
MIRT2375696	hsa-miR-4528	CLIP-seq
MIRT2375697	hsa-miR-4644	CLIP-seq
MIRT2375698	hsa-miR-4768-5p	CLIP-seq
MIRT2375699	hsa-miR-4802-5p	CLIP-seq
MIRT2375700	hsa-miR-510	CLIP-seq
MIRT2375701	hsa-miR-512-5p	CLIP-seq
MIRT2375702	hsa-miR-544	CLIP-seq
MIRT2375703	hsa-miR-550b	CLIP-seq
MIRT2375704	hsa-miR-944	CLIP-seq
MIRT2375705	hsa-miR-96	CLIP-seq
MIRT2668092	hsa-miR-1253	CLIP-seq
MIRT2668093	hsa-miR-3545-3p	CLIP-seq
MIRT2668094	hsa-miR-3684	CLIP-seq
MIRT2668095	hsa-miR-4251	CLIP-seq
MIRT2668096	hsa-miR-4329	CLIP-seq
MIRT2668097	hsa-miR-4680-5p	CLIP-seq
MIRT2668098	hsa-miR-4699-5p	CLIP-seq
MIRT2668099	hsa-miR-4738-3p	CLIP-seq
MIRT1517135	hsa-miR-574-3p	CLIP-seq
MIRT2668100	hsa-miR-618	CLIP-seq
MIRT2668092	hsa-miR-1253	CLIP-seq
MIRT2668094	hsa-miR-3684	CLIP-seq
MIRT2668095	hsa-miR-4251	CLIP-seq
MIRT2668096	hsa-miR-4329	CLIP-seq
MIRT2668098	hsa-miR-4699-5p	CLIP-seq
MIRT1517135	hsa-miR-574-3p	CLIP-seq

Transcription factors

Show/Hide all(2)

Transcription factor	Regulation	Reference
FOXD3	Unknown	19034670
YY1	Activation	19034670

Show/Hide all(16)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IDA	17170456
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IDA	17170456
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	21873635
GO:0001227	Function	DNA-binding transcription repressor activity, RNA polymerase II-specific	IDA	17170456
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	17170456
GO:0003700	Function	DNA-binding transcription factor activity	TAS	8838321
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005654	Component	Nucleoplasm	IDA
GO:0005829	Component	Cytosol	IDA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0045111	Component	Intermediate filament cytoskeleton	IDA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	17170456
GO:0046872	Function	Metal ion binding	IEA
GO:0051607	Process	Defense response to virus	IEA

MIM	HGNC	e!Ensembl
601139	12964	ENSG00000105497

Protein

UniProt ID

Q9Y473

Protein name

Zinc finger protein 175 (Zinc finger protein OTK18)

Protein function

Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat-induced viral LTR promoter activity.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	26 → 67	KRAB box	Family
PF00096	zf-C2H2	335 → 357	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	363 → 385	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	391 → 413	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	419 → 441	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	447 → 469	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	475 → 497	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	503 → 525	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	531 → 553	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	559 → 581	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	587 → 609	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	615 → 637	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	643 → 665	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	671 → 693	Zinc finger, C2H2 type	Domain

Tissue specificity

TISSUE SPECIFICITY: Ubiquitous.

Sequence

MPADVNLSQKPQVLGPEKQDGSCEASVSFEDVTVDFSREEWQQLDPAQRCLYRDVMLELY
SHLFAVGYHIPNPEVIFRMLKEKEPRVEEAEVSHQRCQEREFGLEIPQKEISKKASFQKD
MVGEFTRDGSWCSILEELRLDADRTKKDEQNQIQPMSHSAFFNKKTLNTESNCEYKDPGK
MIRTRPHLASSQKQPQKCCLFTESLKLNLEVNGQNESNDTEQLDDVVGSGQLFSHSSSDA
CSKNIHTGETFCKGNQCRKVCGHKQSLKQHQIHTQKKPDGCSECGGSFTQKSHLFAQQRI
HSVGNLHECGKCGKAFMPQLKLSVYLTDHTGDIPCICKECGKVFIQRSELLTHQKTHTRK
KPYKCHDCGKAFFQMLSLFRHQRTHSREKLYECSECGKGFSQNSTLIIHQKIHTGERQYA
CSECGKAFTQKSTLSLHQRIHSGQKSYVCIECGQAFIQKAHLIVHQRSHTGEKPYQCHNC
GKSFISKSQLDIHHRIHTGEKPYECSDCGKTFTQKSHLNIHQKIHTGERHHVCSECGKAF
NQKSILSMHQRIHTGEKPYKCSECGKAFTSKSQFKEHQRIHTGEKPYVCTECGKAFNGRS
NFHKHQITHTRERPFVCYKCGKAFVQKSELITHQRTHMGEKPYECLDCGKSFSKKPQLKV
HQRIHTGERPYVCSECGKAFNNRSNFNKHQTTHTRDKSYKCSYSVKGFTKQ

Sequence length

711

Interactions

View interactions

	Reactome
			Generic Transcription Pathway

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Rheumatoid arthritis	Rheumatoid Arthritis	rs587776843	22491018

Show/Hide Text Mining Associations (5)

Disease Name	Relationship Type	References
Associations from Text Mining
Encephalitis	Associate	18773297, 19034669, 19034670
HIV Infections	Associate	18773297, 19034669
HIV Infections	Stimulate	19034670
Pre Eclampsia	Associate	26388242
Virus Diseases	Associate	19034669

ZNF175 (zinc finger protein 175)