Gene Gene information from NCBI Gene database.
Entrez ID 7728
Gene name Zinc finger protein 175
Gene symbol ZNF175
Synonyms (NCBI Gene)
OTK18
Chromosome 19
Chromosome location 19q13.41
miRNA miRNA information provided by mirtarbase database.
243
miRTarBase ID miRNA Experiments Reference
MIRT004203 hsa-miR-197-3p Microarray 16822819
MIRT016079 hsa-miR-374b-5p Sequencing 20371350
MIRT017746 hsa-miR-335-5p Microarray 18185580
MIRT611980 hsa-miR-8485 HITS-CLIP 23824327
MIRT611979 hsa-miR-603 HITS-CLIP 23824327
Transcription factors Transcription factors information provided by TRRUST V2 database.
2
Transcription factor Regulation Reference
FOXD3 Unknown 19034670
YY1 Activation 19034670
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
19
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IDA 17170456
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA 17170456
GO:0001227 Function DNA-binding transcription repressor activity, RNA polymerase II-specific IDA 17170456
GO:0001228 Function DNA-binding transcription activator activity, RNA polymerase II-specific IDA 17170456
GO:0001228 Function DNA-binding transcription activator activity, RNA polymerase II-specific IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
601139 12964 ENSG00000105497
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9Y473
Protein name Zinc finger protein 175 (Zinc finger protein OTK18)
Protein function Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat-induced viral LTR promoter activity.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 26 67 KRAB box Family
PF00096 zf-C2H2 335 357 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 363 385 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 391 413 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 419 441 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 447 469 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 475 497 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 503 525 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 531 553 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 559 581 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 587 609 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 615 637 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 643 665 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 671 693 Zinc finger, C2H2 type Domain
Tissue specificity TISSUE SPECIFICITY: Ubiquitous.
Sequence
MPADVNLSQKPQVLGPEKQDGSCEASVSFEDVTVDFSREEWQQLDPAQRCLYRDVMLELY
SHLFAVG
YHIPNPEVIFRMLKEKEPRVEEAEVSHQRCQEREFGLEIPQKEISKKASFQKD
MVGEFTRDGSWCSILEELRLDADRTKKDEQNQIQPMSHSAFFNKKTLNTESNCEYKDPGK
MIRTRPHLASSQKQPQKCCLFTESLKLNLEVNGQNESNDTEQLDDVVGSGQLFSHSSSDA
CSKNIHTGETFCKGNQCRKVCGHKQSLKQHQIHTQKKPDGCSECGGSFTQKSHLFAQQRI
HSVGNLHECGKCGKAFMPQLKLSVYLTDHTGDIPCICKECGKVFIQRSELLTHQKTHTRK
KPYKCHDCGKAFFQMLSLFRHQRTHSREKLYECSECGKGFSQNSTLIIHQKIHTGERQYA
CSECGKAFTQKSTLSLHQRIH
SGQKSYVCIECGQAFIQKAHLIVHQRSHTGEKPYQCHNC
GKSFISKSQLDIHHRIH
TGEKPYECSDCGKTFTQKSHLNIHQKIHTGERHHVCSECGKAF
NQKSILSMHQRIH
TGEKPYKCSECGKAFTSKSQFKEHQRIHTGEKPYVCTECGKAFNGRS
NFHKHQITH
TRERPFVCYKCGKAFVQKSELITHQRTHMGEKPYECLDCGKSFSKKPQLKV
HQRIH
TGERPYVCSECGKAFNNRSNFNKHQTTHTRDKSYKCSYSVKGFTKQ
Sequence length 711
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway