PCGF2 (polycomb group ring finger 2)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7703 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Polycomb group ring finger 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PCGF2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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MEL-18, RNF110, TPFS, ZNF144 |
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Chromosome
Chromosome number
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17 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17q12 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryog |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | P35227 | |||||||||||||||
| Protein name | Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144) | |||||||||||||||
| Protein function | Transcriptional repressor. Binds specifically to the DNA sequence 5'-GACTNGACT-3'. Has tumor suppressor activity. May play a role in control of cell proliferation and/or neural cell development. Regulates proliferation of early T progenitor cell | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Detected in all tissues examined with high expression found in placenta lung and kidney and low expression, in liver, pancreas and skeletal muscle. | |||||||||||||||
| Sequence |
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| Sequence length | 344 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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