ZNF80 (zinc finger protein 80)

Gene

• Entrez ID: 7634
• Gene name: Zinc finger protein 80
• Gene symbol: ZNF80
• Synonyms (NCBI Gene): pT17
• Chromosome: 3
• Chromosome location: 3q13.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT045243	hsa-miR-186-5p	CLASH	23622248
MIRT643117	hsa-miR-4719	HITS-CLIP	23824327
MIRT643117	hsa-miR-4719	HITS-CLIP	23824327
MIRT1540356	hsa-miR-1183	CLIP-seq
MIRT1540357	hsa-miR-200b	CLIP-seq
MIRT1540358	hsa-miR-200c	CLIP-seq
MIRT1540359	hsa-miR-3682-5p	CLIP-seq
MIRT1540360	hsa-miR-429	CLIP-seq
MIRT1540361	hsa-miR-4703-3p	CLIP-seq
MIRT1540362	hsa-miR-4753-3p	CLIP-seq
MIRT1540363	hsa-miR-4768-5p	CLIP-seq
MIRT1540364	hsa-miR-4777-5p	CLIP-seq
MIRT1540365	hsa-miR-518d-5p	CLIP-seq
MIRT1540366	hsa-miR-519b-5p	CLIP-seq
MIRT1540367	hsa-miR-519c-5p	CLIP-seq
MIRT1540368	hsa-miR-520c-5p	CLIP-seq
MIRT1540369	hsa-miR-526a	CLIP-seq
MIRT1540370	hsa-miR-576-3p	CLIP-seq
MIRT1540363	hsa-miR-4768-5p	CLIP-seq
MIRT1540364	hsa-miR-4777-5p	CLIP-seq
MIRT1540365	hsa-miR-518d-5p	CLIP-seq
MIRT1540366	hsa-miR-519b-5p	CLIP-seq
MIRT1540367	hsa-miR-519c-5p	CLIP-seq
MIRT1540368	hsa-miR-520c-5p	CLIP-seq
MIRT1540369	hsa-miR-526a	CLIP-seq
MIRT2464700	hsa-miR-142-5p	CLIP-seq
MIRT2464701	hsa-miR-340	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0008270	Function	Zinc ion binding	IEA
GO:0046872	Function	Metal ion binding	IEA

Other IDs

• MIM: 194553
• HGNC: 13155
• e!Ensembl: ENSG00000174255

Protein

• UniProt ID: P51504
• Protein name: Zinc finger protein 80 (ZNFpT17)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	49 → 71	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	133 → 155	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	161 → 183	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	217 → 239	Zinc finger, C2H2 type	Domain

• Sequence:

  MSPKRDGLGTGDGLHSQVLQEQVSTGDNLHECDSQGPSKDTLVREGKTYKCKECGSVFNK
  NSLLVRHQQIHTGVKPYECQECGKAFPEKVDFVRPMRIHTGEKPCKCVECGKVFNRRSHL
  LCYRQIHTGEKPYECSECGKTFSYHSVFIQHRVTHTGEKLFGCKECGKTFYYNSSLTRHM
  KIHTGEKPCKCSECGKTFTYRSVFFRHSMTHTAGKPYECKECGKGFYYSYSLTRHTRSHT
  GEKPYECLEHRKDFGYHSAFAQQSKIHSGGKNL

• Sequence length: 273

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
MAJOR DEPRESSIVE DISORDER	—	GWAS catalog	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Cardiomyopathy Hypertrophic	Associate	27688314	★☆☆☆☆ Found in Text Mining only