ZNF76 (zinc finger protein 76)

Gene

• Entrez ID: 7629
• Gene name: Zinc finger protein 76
• Gene symbol: ZNF76
• Synonyms (NCBI Gene): D6S229E, ZNF523, Zfp523
• Chromosome: 6
• Chromosome location: 6p21.31

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018904	hsa-miR-335-5p	Microarray	18185580
MIRT048907	hsa-miR-93-5p	CLASH	23622248
MIRT528298	hsa-miR-449b-3p	PAR-CLIP	22012620
MIRT528297	hsa-miR-4491	PAR-CLIP	22012620
MIRT528296	hsa-miR-4657	PAR-CLIP	22012620
MIRT528295	hsa-miR-299-3p	PAR-CLIP	22012620
MIRT528294	hsa-miR-511-3p	PAR-CLIP	22012620
MIRT528293	hsa-miR-4691-3p	PAR-CLIP	22012620
MIRT528292	hsa-miR-663b	PAR-CLIP	22012620
MIRT528291	hsa-miR-597-5p	PAR-CLIP	22012620
MIRT528290	hsa-miR-3157-5p	PAR-CLIP	22012620
MIRT528289	hsa-miR-4701-5p	PAR-CLIP	22012620
MIRT528288	hsa-miR-588	PAR-CLIP	22012620
MIRT528287	hsa-miR-7108-5p	PAR-CLIP	22012620
MIRT528286	hsa-miR-592	PAR-CLIP	22012620
MIRT528285	hsa-miR-7159-3p	PAR-CLIP	22012620
MIRT528298	hsa-miR-449b-3p	PAR-CLIP	22012620
MIRT528297	hsa-miR-4491	PAR-CLIP	22012620
MIRT528296	hsa-miR-4657	PAR-CLIP	22012620
MIRT528295	hsa-miR-299-3p	PAR-CLIP	22012620
MIRT528294	hsa-miR-511-3p	PAR-CLIP	22012620
MIRT528293	hsa-miR-4691-3p	PAR-CLIP	22012620
MIRT528292	hsa-miR-663b	PAR-CLIP	22012620
MIRT528291	hsa-miR-597-5p	PAR-CLIP	22012620
MIRT528290	hsa-miR-3157-5p	PAR-CLIP	22012620
MIRT528289	hsa-miR-4701-5p	PAR-CLIP	22012620
MIRT528288	hsa-miR-588	PAR-CLIP	22012620
MIRT528287	hsa-miR-7108-5p	PAR-CLIP	22012620
MIRT528286	hsa-miR-592	PAR-CLIP	22012620
MIRT528285	hsa-miR-7159-3p	PAR-CLIP	22012620
MIRT1538551	hsa-miR-1227	CLIP-seq
MIRT1538552	hsa-miR-1229	CLIP-seq
MIRT1538553	hsa-miR-1248	CLIP-seq
MIRT1538554	hsa-miR-1254	CLIP-seq
MIRT1538555	hsa-miR-1322	CLIP-seq
MIRT1538556	hsa-miR-2116	CLIP-seq
MIRT1538557	hsa-miR-22	CLIP-seq
MIRT1538558	hsa-miR-3116	CLIP-seq
MIRT1538559	hsa-miR-3127-3p	CLIP-seq
MIRT1538560	hsa-miR-3150b-3p	CLIP-seq
MIRT1538561	hsa-miR-3154	CLIP-seq
MIRT1538562	hsa-miR-3178	CLIP-seq
MIRT1538563	hsa-miR-331-3p	CLIP-seq
MIRT1538564	hsa-miR-3605-5p	CLIP-seq
MIRT1538565	hsa-miR-3616-3p	CLIP-seq
MIRT1538566	hsa-miR-4266	CLIP-seq
MIRT1538567	hsa-miR-4267	CLIP-seq
MIRT1538568	hsa-miR-4313	CLIP-seq
MIRT1538569	hsa-miR-4468	CLIP-seq
MIRT1538570	hsa-miR-4477a	CLIP-seq
MIRT1538571	hsa-miR-4481	CLIP-seq
MIRT1538572	hsa-miR-4494	CLIP-seq
MIRT1538573	hsa-miR-4499	CLIP-seq
MIRT1538574	hsa-miR-455-5p	CLIP-seq
MIRT1538575	hsa-miR-4640-5p	CLIP-seq
MIRT1538576	hsa-miR-4677-5p	CLIP-seq
MIRT1538577	hsa-miR-4693-3p	CLIP-seq
MIRT1538578	hsa-miR-4695-5p	CLIP-seq
MIRT1538579	hsa-miR-4715-3p	CLIP-seq
MIRT1538580	hsa-miR-4716-5p	CLIP-seq
MIRT1538581	hsa-miR-4721	CLIP-seq
MIRT1538582	hsa-miR-4726-5p	CLIP-seq
MIRT1538583	hsa-miR-4740-3p	CLIP-seq
MIRT1538584	hsa-miR-4745-5p	CLIP-seq
MIRT1538585	hsa-miR-4779	CLIP-seq
MIRT1538586	hsa-miR-4784	CLIP-seq
MIRT1538587	hsa-miR-526b	CLIP-seq
MIRT1538588	hsa-miR-609	CLIP-seq
MIRT1538589	hsa-miR-651	CLIP-seq
MIRT1538590	hsa-miR-661	CLIP-seq
MIRT1538591	hsa-miR-765	CLIP-seq
MIRT1538592	hsa-miR-769-5p	CLIP-seq
MIRT2162716	hsa-miR-24	CLIP-seq
MIRT2162717	hsa-miR-3918	CLIP-seq
MIRT2162718	hsa-miR-4284	CLIP-seq
MIRT2381809	hsa-miR-1253	CLIP-seq
MIRT2381810	hsa-miR-1285	CLIP-seq
MIRT2381811	hsa-miR-137	CLIP-seq
MIRT1538560	hsa-miR-3150b-3p	CLIP-seq
MIRT1538561	hsa-miR-3154	CLIP-seq
MIRT2381812	hsa-miR-3179	CLIP-seq
MIRT2381813	hsa-miR-3187-5p	CLIP-seq
MIRT2381814	hsa-miR-4251	CLIP-seq
MIRT2381815	hsa-miR-4324	CLIP-seq
MIRT2381816	hsa-miR-4447	CLIP-seq
MIRT2381817	hsa-miR-4472	CLIP-seq
MIRT2381818	hsa-miR-4488	CLIP-seq
MIRT2381819	hsa-miR-4492	CLIP-seq
MIRT1538572	hsa-miR-4494	CLIP-seq
MIRT2381820	hsa-miR-4498	CLIP-seq
MIRT1538573	hsa-miR-4499	CLIP-seq
MIRT2381821	hsa-miR-4505	CLIP-seq
MIRT2381822	hsa-miR-4684-5p	CLIP-seq
MIRT2381823	hsa-miR-4689	CLIP-seq
MIRT2381824	hsa-miR-4697-5p	CLIP-seq
MIRT1538586	hsa-miR-4784	CLIP-seq
MIRT2381825	hsa-miR-541	CLIP-seq
MIRT2381826	hsa-miR-612	CLIP-seq
MIRT2381827	hsa-miR-654-5p	CLIP-seq
MIRT2381828	hsa-miR-762	CLIP-seq
MIRT2397728	hsa-miR-1207-3p	CLIP-seq
MIRT2397729	hsa-miR-4480	CLIP-seq
MIRT2397730	hsa-miR-4645-5p	CLIP-seq
MIRT2397731	hsa-miR-4673	CLIP-seq
MIRT2397732	hsa-miR-4676-5p	CLIP-seq
MIRT2397733	hsa-miR-4755-3p	CLIP-seq
MIRT2397734	hsa-miR-562	CLIP-seq
MIRT2397735	hsa-miR-575	CLIP-seq
MIRT2466421	hsa-miR-2355-5p	CLIP-seq
MIRT2466422	hsa-miR-4274	CLIP-seq
MIRT2466423	hsa-miR-4530	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IDA	10893243
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IEA
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	32296183, 33961781
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	TAS	9705341
GO:0006359	Process	Regulation of transcription by RNA polymerase III	IEA
GO:0006359	Process	Regulation of transcription by RNA polymerase III	TAS	9705341
GO:0008270	Function	Zinc ion binding	IEA
GO:0043565	Function	Sequence-specific DNA binding	IDA	10893243
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IDA	10893243
GO:0046872	Function	Metal ion binding	IEA
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

Other IDs

• MIM: 194549
• HGNC: 13149
• e!Ensembl: ENSG00000065029

Protein

• UniProt ID: P36508
• Protein name: Zinc finger protein 76 (Zinc finger protein 523)
• Protein function: May be involved in transcriptional regulation.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00096	zf-C2H2	195 → 219	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	225 → 249	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	285 → 309	Zinc finger, C2H2 type	Domain
  PF00096	zf-C2H2	345 → 368	Zinc finger, C2H2 type	Domain

• Tissue specificity: TISSUE SPECIFICITY: Testis.
• Sequence:

  MESLGLHTVTLSDGTTAYVQQAVKGEKLLEGQVIQLEDGTTAYIHQVTVQKEALSFEDGQ
  PVQLEDGSMAYIHRTPREGYDPSTLEAVQLEDGSTAYIHHPVAVPSESTILAVQTEVGLE
  DLAAEDDEGFSADAVVALEQYASKVLHDSQIPRNGKGQQVGDRAFRCGYKGCGRLYTTAH
  HLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHTGEKPYKCPEELCSKAFKTSG
  DLQKHVRTHTGERPFQCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHCGRGFTSAT
  NYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKPYTCSTCGKTYRQTSTL
  AMHKRSAHGELEATEESEQALYEQQQLEAASAAEESPPPKRPRIAYLSEVKEERDDIPAQ
  VAMVTEEDGAPQVALITQDGAQQVSLSPEDLQALGSAISMVTQHGSTTLTIPSPDADLAT
  SGTHTVTMVSADGTQTQPVTIITSGAVVAEDSSVASLRHQQVALLATANGTHIAVQLEEQ
  QTLEEAINVATAAMQQGAVTLETTVSESGC

• Sequence length: 570

Pathways

KEGG:

Cobalamin transport and metabolism