Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
7625
Gene name Gene Name - the full gene name approved by the HGNC.
Zinc finger protein 74
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ZNF74
Synonyms (NCBI Gene) Gene synonyms aliases
COS52, ZFP520, ZNF520, hZNF7
Chromosome Chromosome number
22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q11.21
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT027535 hsa-miR-98-5p Microarray 19088304
MIRT663347 hsa-miR-500b-3p HITS-CLIP 23824327
MIRT663346 hsa-miR-6773-3p HITS-CLIP 23824327
MIRT663345 hsa-miR-215-3p HITS-CLIP 23824327
MIRT663344 hsa-miR-6499-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA 21873635
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA 21873635
GO:0003723 Function RNA binding IEA
GO:0005634 Component Nucleus IBA 21873635
GO:0005654 Component Nucleoplasm IDA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
194548 13144 ENSG00000185252
Protein
UniProt ID Q16587
Protein name Zinc finger protein 74 (Zinc finger protein 520) (hZNF7)
Protein function May play a role in RNA metabolism.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01352 KRAB 42 83 KRAB box Family
PF00096 zf-C2H2 248 270 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 276 298 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 304 326 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 360 382 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 416 438 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 472 494 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 528 550 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 556 578 Zinc finger, C2H2 type Domain
Tissue specificity TISSUE SPECIFICITY: Highly expressed in the fetal brain.
Sequence
MEIPAPEPEKTALSSQDPALSLKENLEDISGWGLPEARSKESVSFKDVAVDFTQEEWGQL
DSPQRALYRDVMLENYQNLLALG
PPLHKPDVISHLERGEEPWSMQREVPRGPCPEWELKA
VPSQQQGICKEEPAQEPIMERPLGGAQAWGRQAGALQRSQAAPWAPAPAMVWDVPVEEFP
LRCPLFAQQRVPEGGPLLDTRKNVQATEGRTKAPARLCAGENASTPSEPEKFPQVRRQRG
AGAGEGEFVCGECGKAFRQSSSLTLHRRWHSREKAYKCDECGKAFTWSTNLLEHRRIHTG
EKPFFCGECGKAFSCHSSLNVHQRIHTGERPYKCSACEKAFSCSSLLSMHLRVHTGEKPY
RCGECGKAFNQRTHLTRHHRIH
TGEKPYQCGSCGKAFTCHSSLTVHEKIHSGDKPFKCSD
CEKAFNSRSRLTLHQRTH
TGEKPFKCADCGKGFSCHAYLLVHRRIHSGEKPFKCNECGKA
FSSHAYLIVHRRIH
TGEKPFDCSQCWKAFSCHSSLIVHQRIHTGEKPYKCSECGRAFSQN
HCLIKHQKIH
SGEKSFKCEKCGEMFNWSSHLTEHQRLHSEGKPLAIQFNKHLLSTYYVPG
SLLGAGDAGLRDVDPIDALDVAKLLCVVPPRAGRNFSLGSKPRN
Sequence length 644
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)
11705709
Associations from Text Mining
Disease Name Relationship Type References
DiGeorge Syndrome Inhibit 8663113