Gene Gene information from NCBI Gene database.
Entrez ID 7621
Gene name Zinc finger protein 70
Gene symbol ZNF70
Synonyms (NCBI Gene)
Cos17
Chromosome 22
Chromosome location 22q11.23
miRNA miRNA information provided by mirtarbase database.
572
miRTarBase ID miRNA Experiments Reference
MIRT693989 hsa-miR-6502-3p HITS-CLIP 23313552
MIRT693988 hsa-miR-4793-5p HITS-CLIP 23313552
MIRT693987 hsa-miR-221-5p HITS-CLIP 23313552
MIRT693986 hsa-miR-8073 HITS-CLIP 23313552
MIRT693985 hsa-miR-3190-5p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
11
GO ID Ontology Definition Evidence Reference
GO:0000977 Function RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA
GO:0003677 Function DNA binding IEA
GO:0005515 Function Protein binding IPI 27353377
GO:0005634 Component Nucleus IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
194544 13140 ENSG00000187792
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9UC06
Protein name Zinc finger protein 70 (Zinc finger protein N27C7-1)
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00096 zf-C2H2 140 162 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 168 190 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 196 218 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 224 246 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 252 274 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 280 302 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 308 330 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 336 358 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 364 386 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 419 441 Zinc finger, C2H2 type Domain
Sequence
MEVPPATKFGETFAFENRLESQQGLFPGEDLGDPFLQERGLEQMAVIYKEIPLGEQDEEN
DDYEGNFSLCSSPVQHQSIPPGTRPQDDELFGQTFLQKSDLSMCQIIHSEEPSPCDCAET
DRGDSGPNAPHRTPQPAKPYACRECGKAFSQSSHLLRHLVIHTGEKPYECCECGKAFSQS
SHLLRHQIIH
TGEKPYECRECGKAFRQSSALTQHQKIHTGKRPYECRECGKDFSRSSSLR
KHERIH
TGERPYQCKECGKSFNQSSGLSQHRKIHTLKKPHECDLCGKAFCHRSHLIRHQR
IH
TGKKPYKCDECGKAFSQSSNLIEHRKTHTGEKPYKCQKCGKAFSQSSSLIEHQRIHTG
EKPYECCQCGKAFCHSSALIQHQRIHTGKKPYTCECGKAFRHRSALIEHYKTHTREKPYV
CNLCGKSFRGSSHLIRHQKIH
SGEKL
Sequence length 446
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
1
Evidence Score: ★☆☆☆☆  Gene-disease association found in Text Mining only ★★☆☆☆  Found in Text Mining and Unknown/Other Associations ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants) ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
Unknown / Other Associations ClinVar entries with uncertain/conflicting evidence, and associations from other databases (OMIM, Orphanet, GWAS, etc.) where the gene is not established as causal.
Phenotype Name Clinical Significance Source Evidence Score
ALZHEIMER DISEASE GWAS catalog
★★☆☆☆
Found in Text Mining + Unknown/Other Associations
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References Evidence Score
Psychological Distress Associate 37821882
★☆☆☆☆
Found in Text Mining only