Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	7596
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc finger protein 45
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZNF45
Synonyms (NCBI Gene) Gene synonyms aliases	KOX5, ZNF13
Chromosome Chromosome number	19
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	19q13.31

Show/Hide all(61)

miRTarBase ID	miRNA	Experiments	Reference
MIRT020361	hsa-miR-29c-3p	Sequencing	20371350
MIRT024670	hsa-miR-215-5p	Microarray	19074876
MIRT026769	hsa-miR-192-5p	Microarray	19074876
MIRT046226	hsa-miR-27b-3p	CLASH	23622248
MIRT571369	hsa-miR-6871-3p	PAR-CLIP	20371350
MIRT571368	hsa-miR-3200-5p	PAR-CLIP	20371350
MIRT571367	hsa-miR-205-3p	PAR-CLIP	20371350
MIRT571366	hsa-miR-3065-3p	PAR-CLIP	20371350
MIRT571365	hsa-miR-383-3p	PAR-CLIP	20371350
MIRT571364	hsa-miR-4251	PAR-CLIP	20371350
MIRT571362	hsa-miR-4329	PAR-CLIP	20371350
MIRT571363	hsa-miR-6761-5p	PAR-CLIP	20371350
MIRT571361	hsa-miR-4291	PAR-CLIP	20371350
MIRT571369	hsa-miR-6871-3p	PAR-CLIP	20371350
MIRT571368	hsa-miR-3200-5p	PAR-CLIP	20371350
MIRT571367	hsa-miR-205-3p	PAR-CLIP	20371350
MIRT571366	hsa-miR-3065-3p	PAR-CLIP	20371350
MIRT571365	hsa-miR-383-3p	PAR-CLIP	20371350
MIRT571364	hsa-miR-4251	PAR-CLIP	20371350
MIRT571362	hsa-miR-4329	PAR-CLIP	20371350
MIRT571363	hsa-miR-6761-5p	PAR-CLIP	20371350
MIRT571361	hsa-miR-4291	PAR-CLIP	20371350
MIRT1525454	hsa-miR-3682-3p	CLIP-seq
MIRT2158785	hsa-miR-1911	CLIP-seq
MIRT2158786	hsa-miR-298	CLIP-seq
MIRT2158787	hsa-miR-299-5p	CLIP-seq
MIRT2158788	hsa-miR-3182	CLIP-seq
MIRT2158789	hsa-miR-3622a-5p	CLIP-seq
MIRT2158790	hsa-miR-3678-3p	CLIP-seq
MIRT2158791	hsa-miR-3714	CLIP-seq
MIRT2158792	hsa-miR-4303	CLIP-seq
MIRT2158793	hsa-miR-4423-3p	CLIP-seq
MIRT2158794	hsa-miR-4427	CLIP-seq
MIRT2158795	hsa-miR-455-3p	CLIP-seq
MIRT2158796	hsa-miR-4659a-3p	CLIP-seq
MIRT2158797	hsa-miR-4659b-3p	CLIP-seq
MIRT2158798	hsa-miR-4680-3p	CLIP-seq
MIRT2158799	hsa-miR-4682	CLIP-seq
MIRT2158800	hsa-miR-4691-5p	CLIP-seq
MIRT2158801	hsa-miR-548an	CLIP-seq
MIRT2158802	hsa-miR-633	CLIP-seq
MIRT2158803	hsa-miR-654-3p	CLIP-seq
MIRT2158804	hsa-miR-659	CLIP-seq
MIRT2378231	hsa-miR-1278	CLIP-seq
MIRT2158794	hsa-miR-4427	CLIP-seq
MIRT2158795	hsa-miR-455-3p	CLIP-seq
MIRT2158798	hsa-miR-4680-3p	CLIP-seq
MIRT2158800	hsa-miR-4691-5p	CLIP-seq
MIRT2158803	hsa-miR-654-3p	CLIP-seq
MIRT2670558	hsa-miR-2052	CLIP-seq
MIRT2670559	hsa-miR-3163	CLIP-seq
MIRT2670560	hsa-miR-3920	CLIP-seq
MIRT2670561	hsa-miR-4307	CLIP-seq
MIRT2670562	hsa-miR-4477a	CLIP-seq
MIRT2670563	hsa-miR-4522	CLIP-seq
MIRT2670564	hsa-miR-4796-5p	CLIP-seq
MIRT2670558	hsa-miR-2052	CLIP-seq
MIRT2670559	hsa-miR-3163	CLIP-seq
MIRT2670561	hsa-miR-4307	CLIP-seq
MIRT2670563	hsa-miR-4522	CLIP-seq
MIRT2670564	hsa-miR-4796-5p	CLIP-seq

Show/Hide all(9)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000978	Function	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA	21873635
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA	21873635
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA	21873635
GO:0006367	Process	Transcription initiation from RNA polymerase II promoter	TAS
GO:0007275	Process	Multicellular organism development	TAS	1559709
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
194554	13111	ENSG00000124459

Protein

UniProt ID

Q02386

Protein name

Zinc finger protein 45 (BRC1744) (Zinc finger protein 13) (Zinc finger protein KOX5)

Protein function

May be involved in transcriptional regulation.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01352	KRAB	7 → 48	KRAB box	Family
PF00096	zf-C2H2	192 → 214	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	276 → 298	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	304 → 326	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	332 → 354	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	360 → 382	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	388 → 410	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	416 → 438	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	444 → 466	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	472 → 494	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	500 → 522	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	528 → 550	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	556 → 578	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	584 → 606	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	612 → 634	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	640 → 662	Zinc finger, C2H2 type	Domain

Sequence

MTKSKEAVTFKDVAVVFSEEELQLLDLAQRKLYRDVMLENFRNVVSVGHQSTPDGLPQLE
REEKLWMMKMATQRDNSSGAKNLKEMETLQEVGLRYLPHEELFCSQIWQQITRELIKYQD
SVVNIQRTGCQLEKRDDLHYKDEGFSNQSSHLQVHRVHTGEKPYKGEHCVKSFSWSSHLQ
INQRAHAGEKPYKCEKCDNAFRRFSSLQAHQRVHSRAKSYTNDASYRSFSQRSHLPHHQR
VPTGENPYKYEECGRNVGKSSHCQAPLIVHTGEKPYKCEECGVGFSQRSYLQVHLKVHTG
KKPYKCEECGKSFSWRSRLQAHERIHTGEKPYKCNACGKSFSYSSHLNIHCRIHTGEKPY
KCEECGKGFSVGSHLQAHQISHTGEKPYKCEECGKGFCRASNLLDHQRGHTGEKPYQCDA
CGKGFSRSSDFNIHFRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCGTCGKG
FSRSSDLNVHCRIHTGEKPYKCERCGKAFSQFSSLQVHQRVHTGEKPYQCAECGKGFSVG
SQLQAHQRCHTGEKPYQCEECGKGFCRASNFLAHRGVHTGEKPYRCDVCGKRFRQRSYLQ
AHQRVHTGERPYKCEECGKVFSWSSYLQAHQRVHTGEKPYKCEECGKGFSWSSSLIIHQR
VHADDEGDKDFPSSEDSHRKTR

Sequence length

682

Interactions

View interactions

	Reactome
			Generic Transcription Pathway

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Breast carcinoma	Breast Carcinoma	rs80359671, rs11540652, rs28934575, rs28897672, rs137886232, rs193922376, rs80357783, rs80359306, rs80359405, rs80359507, rs80359598, rs80358429, rs397507683, rs397515636, rs80359451 View all (71 more)	29059683

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Breast Cancer	Breast Cancer	Importantly, breast cancer patients bearing PRC2 LOF mutations displayed significantly worse prognosis compared with PRC2 wild-type patients		GWAS, CBGDA

Show/Hide Text Mining Associations (1)

Disease Name	Relationship Type	References
Associations from Text Mining
Alzheimer Disease	Associate	37354922

ZNF45 (zinc finger protein 45)