Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
7586
Gene name Gene Name - the full gene name approved by the HGNC.
Zinc finger with KRAB and SCAN domains 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ZKSCAN1
Synonyms (NCBI Gene) Gene synonyms aliases
KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7q22.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the Kruppel C2H2-type zinc-finger family of proteins. This encoded protein may function as a transcription factor that regulates the expression of GABA type-A receptors in the brain. Transcripts from this gene have been shown
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT665264 hsa-miR-6513-3p HITS-CLIP 23824327
MIRT639834 hsa-miR-4716-5p HITS-CLIP 23824327
MIRT639833 hsa-miR-4485-5p HITS-CLIP 23824327
MIRT639832 hsa-miR-1281 HITS-CLIP 23824327
MIRT639830 hsa-miR-2116-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000978 Function RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA 21873635
GO:0000981 Function DNA-binding transcription factor activity, RNA polymerase II-specific IBA 21873635
GO:0005515 Function Protein binding IPI 25416956, 28514442, 31515488, 32296183, 32814053
GO:0005634 Component Nucleus IEA
GO:0006357 Process Regulation of transcription by RNA polymerase II IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
601260 13101 ENSG00000106261
Protein
UniProt ID P17029
Protein name Zinc finger protein with KRAB and SCAN domains 1 (Zinc finger protein 139) (Zinc finger protein 36) (Zinc finger protein KOX18)
Protein function May be involved in transcriptional regulation.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF02023 SCAN 52 141 SCAN domain Domain
PF01352 KRAB 226 266 KRAB box Family
PF00096 zf-C2H2 377 399 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 405 427 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 433 455 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 461 483 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 489 511 Zinc finger, C2H2 type Domain
PF00096 zf-C2H2 517 539 Zinc finger, C2H2 type Domain
Sequence
MMTAESREATGLSPQAAQEKDGIVIVKVEEEDEEDHMWGQDSTLQDTPPPDPEIFRQRFR
RFCYQNTFGPREALSRLKELCHQWLRPEINTKEQILELLVLEQFLSILPKELQVWLQEYR
PDSGEEAVTLLEDLELDLSGQ
QVPGQVHGPEMLARGMVPLDPVQESSSFDLHHEATQSHF
KHSSRKPRLLQSRALPAAHIPAPPHEGSPRDQAMASALFTADSQAMVKIEDMAVSLILEE
WGCQNLARRNLSRDNRQENYGSAFPQ
GGENRNENEESTSKAETSEDSASRGETTGRSQKE
FGEKRDQEGKTGERQQKNPEEKTRKEKRDSGPAIGKDKKTITGERGPREKGKGLGRSFSL
SSNFTTPEEVPTGTKSHRCDECGKCFTRSSSLIRHKIIHTGEKPYECSECGKAFSLNSNL
VLHQRIH
TGEKPHECNECGKAFSHSSNLILHQRIHSGEKPYECNECGKAFSQSSDLTKHQ
RIH
TGEKPYECSECGKAFNRNSYLILHRRIHTREKPYKCTKCGKAFTRSSTLTLHHRIHA
RERASEYSPASLDAFGAFLKSCV
Sequence length 563
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Generic Transcription Pathway
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Chronic obstructive pulmonary disease Chronic Obstructive Airway Disease 30804561 ClinVar
Pulmonary Fibrosis Pulmonary Fibrosis GWAS
Coronary artery disease Coronary artery disease GWAS
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma of Lung Associate 27923066
Carcinoma Renal Cell Associate 35285410
Lymphatic Metastasis Stimulate 25561801
Neoplasms Associate 25561801, 27923066, 32454461, 35285410, 36749875
Stomach Neoplasms Associate 25561801, 26722429, 29956811, 30126848
Tuberculosis Multidrug Resistant Associate 29956811, 30126848
Urinary Bladder Neoplasms Stimulate 32454461