PTTG1IP (PTTG1 interacting protein)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 754 |
| Gene name | PTTG1 interacting protein |
| Gene symbol | PTTG1IP |
| Synonyms (NCBI Gene) |
C21orf1C21orf3PBFPTTG1IP1
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| Chromosome | 21 |
| Chromosome location | 21q22.3 |
| Summary | This gene encodes a single-pass type I integral membrane protein, which binds to pituitary tumor-transforming 1 protein (PTTG1), and facilitates translocation of PTTG1 into the nucleus. Coexpression of this protein and PTTG1 induces transcriptional activa |
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miRNA
miRNA information provided by mirtarbase database.
686
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Transcription factors
Transcription factors information provided by TRRUST V2 database.
1
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
17
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P53801 | |
| Protein name | Pituitary tumor-transforming gene 1 protein-interacting protein (Pituitary tumor-transforming gene protein-binding factor) (PBF) (PTTG-binding factor) | |
| Protein function | May facilitate PTTG1 nuclear translocation. | |
| Family and domains | ||
| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. | |
| Sequence |
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| Sequence length | 180 | |
| Interactions | View interactions | |
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Associated diseases
Disease associations from ClinVar (causal & non-causal) and other databases (OMIM, Orphanet, GWAS, etc.).
9
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Evidence Score:
★☆☆☆☆ Gene-disease association found in Text Mining only
★★☆☆☆ Found in Text Mining and Unknown/Other Associations
★★★☆☆ Reported in Unknown/Other Associations across ≥2 Sources
★★★★☆ ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
★★★★★ ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)
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