Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	7520
Gene name Gene Name - the full gene name approved by the HGNC.	X-ray repair cross complementing 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	XRCC5
Synonyms (NCBI Gene) Gene synonyms aliases	KARP-1, KARP1, KU80, KUB2, Ku86, NFIV
Chromosome Chromosome number	2
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	2q35
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it funct

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miRTarBase ID	miRNA	Experiments	Reference
MIRT050041	hsa-miR-26b-5p	CLASH	23622248
MIRT048471	hsa-miR-100-5p	CLASH	23622248
MIRT047762	hsa-miR-7-5p	CLASH	23622248
MIRT043483	hsa-miR-331-3p	CLASH	23622248
MIRT042031	hsa-miR-484	CLASH	23622248
MIRT712072	hsa-miR-2115-3p	HITS-CLIP	19536157
MIRT712071	hsa-miR-1324	HITS-CLIP	19536157
MIRT712070	hsa-miR-6840-3p	HITS-CLIP	19536157
MIRT712069	hsa-miR-1915-3p	HITS-CLIP	19536157
MIRT712068	hsa-miR-6764-5p	HITS-CLIP	19536157
MIRT712067	hsa-miR-4726-3p	HITS-CLIP	19536157
MIRT712066	hsa-miR-3927-5p	HITS-CLIP	19536157
MIRT712065	hsa-miR-92a-2-5p	HITS-CLIP	19536157
MIRT712064	hsa-miR-361-5p	HITS-CLIP	19536157
MIRT119400	hsa-miR-7977	HITS-CLIP	19536157
MIRT651438	hsa-miR-29b-1-5p	HITS-CLIP	23824327
MIRT651437	hsa-miR-218-2-3p	HITS-CLIP	23824327
MIRT651436	hsa-miR-758-5p	HITS-CLIP	23824327
MIRT651434	hsa-miR-4528	HITS-CLIP	23824327
MIRT651435	hsa-miR-584-5p	HITS-CLIP	23824327
MIRT712072	hsa-miR-2115-3p	HITS-CLIP	19536157
MIRT712071	hsa-miR-1324	HITS-CLIP	19536157
MIRT712070	hsa-miR-6840-3p	HITS-CLIP	19536157
MIRT712069	hsa-miR-1915-3p	HITS-CLIP	19536157
MIRT712068	hsa-miR-6764-5p	HITS-CLIP	19536157
MIRT712067	hsa-miR-4726-3p	HITS-CLIP	19536157
MIRT712066	hsa-miR-3927-5p	HITS-CLIP	19536157
MIRT712065	hsa-miR-92a-2-5p	HITS-CLIP	19536157
MIRT712064	hsa-miR-361-5p	HITS-CLIP	19536157
MIRT119400	hsa-miR-7977	HITS-CLIP	19536157
MIRT651438	hsa-miR-29b-1-5p	HITS-CLIP	23824327
MIRT651437	hsa-miR-218-2-3p	HITS-CLIP	23824327
MIRT651436	hsa-miR-758-5p	HITS-CLIP	23824327
MIRT651434	hsa-miR-4528	HITS-CLIP	23824327
MIRT651435	hsa-miR-584-5p	HITS-CLIP	23824327
MIRT1497389	hsa-miR-105	CLIP-seq
MIRT1497390	hsa-miR-1224-3p	CLIP-seq
MIRT1497391	hsa-miR-1224-5p	CLIP-seq
MIRT1497392	hsa-miR-1225-5p	CLIP-seq
MIRT1497393	hsa-miR-1260	CLIP-seq
MIRT1497394	hsa-miR-1260b	CLIP-seq
MIRT1497395	hsa-miR-1280	CLIP-seq
MIRT1497396	hsa-miR-1281	CLIP-seq
MIRT1497397	hsa-miR-1298	CLIP-seq
MIRT1497398	hsa-miR-1323	CLIP-seq
MIRT1497399	hsa-miR-134	CLIP-seq
MIRT1497400	hsa-miR-140-3p	CLIP-seq
MIRT1497401	hsa-miR-1827	CLIP-seq
MIRT1497402	hsa-miR-186	CLIP-seq
MIRT1497403	hsa-miR-188-3p	CLIP-seq
MIRT1497404	hsa-miR-188-5p	CLIP-seq
MIRT1497405	hsa-miR-2054	CLIP-seq
MIRT1497406	hsa-miR-218	CLIP-seq
MIRT1497407	hsa-miR-2355-5p	CLIP-seq
MIRT1497408	hsa-miR-297	CLIP-seq
MIRT1497409	hsa-miR-300	CLIP-seq
MIRT1497410	hsa-miR-31	CLIP-seq
MIRT1497411	hsa-miR-3118	CLIP-seq
MIRT1497412	hsa-miR-3123	CLIP-seq
MIRT1497413	hsa-miR-3125	CLIP-seq
MIRT1497414	hsa-miR-3127-3p	CLIP-seq
MIRT1497415	hsa-miR-3133	CLIP-seq
MIRT1497416	hsa-miR-3149	CLIP-seq
MIRT1497417	hsa-miR-3156-3p	CLIP-seq
MIRT1497418	hsa-miR-3156-5p	CLIP-seq
MIRT1497419	hsa-miR-3158-3p	CLIP-seq
MIRT1497420	hsa-miR-3179	CLIP-seq
MIRT1497421	hsa-miR-3180-5p	CLIP-seq
MIRT1497422	hsa-miR-320a	CLIP-seq
MIRT1497423	hsa-miR-320b	CLIP-seq
MIRT1497424	hsa-miR-320c	CLIP-seq
MIRT1497425	hsa-miR-320d	CLIP-seq
MIRT1497426	hsa-miR-330-3p	CLIP-seq
MIRT1497427	hsa-miR-338-3p	CLIP-seq
MIRT1497428	hsa-miR-340	CLIP-seq
MIRT1497429	hsa-miR-3606	CLIP-seq
MIRT1497430	hsa-miR-3667-5p	CLIP-seq
MIRT1497431	hsa-miR-3675-5p	CLIP-seq
MIRT1497432	hsa-miR-3680	CLIP-seq
MIRT1497433	hsa-miR-3692	CLIP-seq
MIRT1497434	hsa-miR-370	CLIP-seq
MIRT1497435	hsa-miR-380	CLIP-seq
MIRT1497436	hsa-miR-381	CLIP-seq
MIRT1497437	hsa-miR-3916	CLIP-seq
MIRT1497438	hsa-miR-3919	CLIP-seq
MIRT1497439	hsa-miR-3922-5p	CLIP-seq
MIRT1497440	hsa-miR-3928	CLIP-seq
MIRT1497441	hsa-miR-4257	CLIP-seq
MIRT1497442	hsa-miR-4286	CLIP-seq
MIRT1497443	hsa-miR-4311	CLIP-seq
MIRT1497444	hsa-miR-4327	CLIP-seq
MIRT1497445	hsa-miR-4422	CLIP-seq
MIRT1497446	hsa-miR-4429	CLIP-seq
MIRT1497447	hsa-miR-4454	CLIP-seq
MIRT1497448	hsa-miR-4495	CLIP-seq
MIRT1497449	hsa-miR-4522	CLIP-seq
MIRT1497450	hsa-miR-4660	CLIP-seq
MIRT1497451	hsa-miR-4666-3p	CLIP-seq
MIRT1497452	hsa-miR-4666-5p	CLIP-seq
MIRT1497453	hsa-miR-4720-3p	CLIP-seq
MIRT1497454	hsa-miR-4731-5p	CLIP-seq
MIRT1497455	hsa-miR-4751	CLIP-seq
MIRT1497456	hsa-miR-4760-5p	CLIP-seq
MIRT1497457	hsa-miR-4786-5p	CLIP-seq
MIRT1497458	hsa-miR-4797-5p	CLIP-seq
MIRT1497459	hsa-miR-4799-5p	CLIP-seq
MIRT1497460	hsa-miR-4804-3p	CLIP-seq
MIRT1497461	hsa-miR-490-3p	CLIP-seq
MIRT1497462	hsa-miR-520a-5p	CLIP-seq
MIRT1497463	hsa-miR-520d-5p	CLIP-seq
MIRT1497464	hsa-miR-524-5p	CLIP-seq
MIRT1497465	hsa-miR-525-5p	CLIP-seq
MIRT1497466	hsa-miR-548a-3p	CLIP-seq
MIRT1497467	hsa-miR-548aa	CLIP-seq
MIRT1497468	hsa-miR-548e	CLIP-seq
MIRT1497469	hsa-miR-548f	CLIP-seq
MIRT1497470	hsa-miR-548g	CLIP-seq
MIRT1497471	hsa-miR-548o	CLIP-seq
MIRT1497472	hsa-miR-567	CLIP-seq
MIRT1497473	hsa-miR-583	CLIP-seq
MIRT1497474	hsa-miR-615-5p	CLIP-seq
MIRT1497475	hsa-miR-630	CLIP-seq
MIRT1497476	hsa-miR-643	CLIP-seq
MIRT1497477	hsa-miR-649	CLIP-seq
MIRT1497478	hsa-miR-664	CLIP-seq
MIRT1497479	hsa-miR-769-5p	CLIP-seq
MIRT1497480	hsa-miR-885-3p	CLIP-seq
MIRT1497481	hsa-miR-892a	CLIP-seq
MIRT1497482	hsa-miR-921	CLIP-seq
MIRT1497389	hsa-miR-105	CLIP-seq
MIRT2149803	hsa-miR-1178	CLIP-seq
MIRT1497391	hsa-miR-1224-5p	CLIP-seq
MIRT1497392	hsa-miR-1225-5p	CLIP-seq
MIRT2149804	hsa-miR-1273d	CLIP-seq
MIRT1497396	hsa-miR-1281	CLIP-seq
MIRT1497397	hsa-miR-1298	CLIP-seq
MIRT2149805	hsa-miR-1299	CLIP-seq
MIRT1497399	hsa-miR-134	CLIP-seq
MIRT2149806	hsa-miR-183	CLIP-seq
MIRT2149807	hsa-miR-190	CLIP-seq
MIRT2149808	hsa-miR-190b	CLIP-seq
MIRT2149809	hsa-miR-2052	CLIP-seq
MIRT1497405	hsa-miR-2054	CLIP-seq
MIRT1497408	hsa-miR-297	CLIP-seq
MIRT1497409	hsa-miR-300	CLIP-seq
MIRT1497410	hsa-miR-31	CLIP-seq
MIRT1497411	hsa-miR-3118	CLIP-seq
MIRT1497412	hsa-miR-3123	CLIP-seq
MIRT1497414	hsa-miR-3127-3p	CLIP-seq
MIRT2149810	hsa-miR-3147	CLIP-seq
MIRT1497416	hsa-miR-3149	CLIP-seq
MIRT1497418	hsa-miR-3156-5p	CLIP-seq
MIRT2149811	hsa-miR-3173-3p	CLIP-seq
MIRT1497421	hsa-miR-3180-5p	CLIP-seq
MIRT1497422	hsa-miR-320a	CLIP-seq
MIRT1497423	hsa-miR-320b	CLIP-seq
MIRT1497424	hsa-miR-320c	CLIP-seq
MIRT1497425	hsa-miR-320d	CLIP-seq
MIRT1497426	hsa-miR-330-3p	CLIP-seq
MIRT1497427	hsa-miR-338-3p	CLIP-seq
MIRT1497428	hsa-miR-340	CLIP-seq
MIRT2149812	hsa-miR-3653	CLIP-seq
MIRT2149813	hsa-miR-3658	CLIP-seq
MIRT1497431	hsa-miR-3675-5p	CLIP-seq
MIRT2149814	hsa-miR-3689a-3p	CLIP-seq
MIRT2149815	hsa-miR-3689c	CLIP-seq
MIRT1497433	hsa-miR-3692	CLIP-seq
MIRT1497434	hsa-miR-370	CLIP-seq
MIRT1497435	hsa-miR-380	CLIP-seq
MIRT1497436	hsa-miR-381	CLIP-seq
MIRT1497438	hsa-miR-3919	CLIP-seq
MIRT1497439	hsa-miR-3922-5p	CLIP-seq
MIRT2149816	hsa-miR-3978	CLIP-seq
MIRT1497441	hsa-miR-4257	CLIP-seq
MIRT2149817	hsa-miR-4269	CLIP-seq
MIRT1497442	hsa-miR-4286	CLIP-seq
MIRT1497444	hsa-miR-4327	CLIP-seq
MIRT1497445	hsa-miR-4422	CLIP-seq
MIRT2149818	hsa-miR-4425	CLIP-seq
MIRT1497446	hsa-miR-4429	CLIP-seq
MIRT2149819	hsa-miR-4443	CLIP-seq
MIRT1497447	hsa-miR-4454	CLIP-seq
MIRT1497448	hsa-miR-4495	CLIP-seq
MIRT2149820	hsa-miR-4514	CLIP-seq
MIRT1497449	hsa-miR-4522	CLIP-seq
MIRT2149821	hsa-miR-4646-5p	CLIP-seq
MIRT1497450	hsa-miR-4660	CLIP-seq
MIRT1497451	hsa-miR-4666-3p	CLIP-seq
MIRT2149822	hsa-miR-4692	CLIP-seq
MIRT2149823	hsa-miR-4728-5p	CLIP-seq
MIRT1497454	hsa-miR-4731-5p	CLIP-seq
MIRT2149824	hsa-miR-4742-5p	CLIP-seq
MIRT1497455	hsa-miR-4751	CLIP-seq
MIRT1497456	hsa-miR-4760-5p	CLIP-seq
MIRT2149825	hsa-miR-4772-5p	CLIP-seq
MIRT2149826	hsa-miR-4780	CLIP-seq
MIRT2149827	hsa-miR-4790-3p	CLIP-seq
MIRT1497459	hsa-miR-4799-5p	CLIP-seq
MIRT1497461	hsa-miR-490-3p	CLIP-seq
MIRT1497462	hsa-miR-520a-5p	CLIP-seq
MIRT1497463	hsa-miR-520d-5p	CLIP-seq
MIRT1497464	hsa-miR-524-5p	CLIP-seq
MIRT1497465	hsa-miR-525-5p	CLIP-seq
MIRT2149828	hsa-miR-526b	CLIP-seq
MIRT1497472	hsa-miR-567	CLIP-seq
MIRT2149829	hsa-miR-578	CLIP-seq
MIRT1497476	hsa-miR-643	CLIP-seq
MIRT1497477	hsa-miR-649	CLIP-seq
MIRT1497478	hsa-miR-664	CLIP-seq
MIRT2149830	hsa-miR-765	CLIP-seq
MIRT2149831	hsa-miR-875-3p	CLIP-seq
MIRT1497480	hsa-miR-885-3p	CLIP-seq
MIRT1497481	hsa-miR-892a	CLIP-seq
MIRT1497389	hsa-miR-105	CLIP-seq
MIRT2149803	hsa-miR-1178	CLIP-seq
MIRT1497392	hsa-miR-1225-5p	CLIP-seq
MIRT2149804	hsa-miR-1273d	CLIP-seq
MIRT1497396	hsa-miR-1281	CLIP-seq
MIRT1497397	hsa-miR-1298	CLIP-seq
MIRT1497399	hsa-miR-134	CLIP-seq
MIRT1497400	hsa-miR-140-3p	CLIP-seq
MIRT2149806	hsa-miR-183	CLIP-seq
MIRT2149807	hsa-miR-190	CLIP-seq
MIRT2149808	hsa-miR-190b	CLIP-seq
MIRT1497405	hsa-miR-2054	CLIP-seq
MIRT1497408	hsa-miR-297	CLIP-seq
MIRT1497409	hsa-miR-300	CLIP-seq
MIRT2369949	hsa-miR-3117-5p	CLIP-seq
MIRT1497411	hsa-miR-3118	CLIP-seq
MIRT1497412	hsa-miR-3123	CLIP-seq
MIRT2149810	hsa-miR-3147	CLIP-seq
MIRT1497418	hsa-miR-3156-5p	CLIP-seq
MIRT1497421	hsa-miR-3180-5p	CLIP-seq
MIRT1497426	hsa-miR-330-3p	CLIP-seq
MIRT2369950	hsa-miR-34b	CLIP-seq
MIRT2149814	hsa-miR-3689a-3p	CLIP-seq
MIRT2149815	hsa-miR-3689c	CLIP-seq
MIRT1497433	hsa-miR-3692	CLIP-seq
MIRT1497434	hsa-miR-370	CLIP-seq
MIRT1497435	hsa-miR-380	CLIP-seq
MIRT1497436	hsa-miR-381	CLIP-seq
MIRT2369951	hsa-miR-382	CLIP-seq
MIRT1497438	hsa-miR-3919	CLIP-seq
MIRT1497441	hsa-miR-4257	CLIP-seq
MIRT2369952	hsa-miR-4263	CLIP-seq
MIRT2149817	hsa-miR-4269	CLIP-seq
MIRT1497443	hsa-miR-4311	CLIP-seq
MIRT1497444	hsa-miR-4327	CLIP-seq
MIRT2369953	hsa-miR-4328	CLIP-seq
MIRT2369954	hsa-miR-4420	CLIP-seq
MIRT1497445	hsa-miR-4422	CLIP-seq
MIRT2149818	hsa-miR-4425	CLIP-seq
MIRT2149819	hsa-miR-4443	CLIP-seq
MIRT2369955	hsa-miR-4446-3p	CLIP-seq
MIRT1497447	hsa-miR-4454	CLIP-seq
MIRT2369956	hsa-miR-4457	CLIP-seq
MIRT1497448	hsa-miR-4495	CLIP-seq
MIRT2369957	hsa-miR-4509	CLIP-seq
MIRT2149820	hsa-miR-4514	CLIP-seq
MIRT1497449	hsa-miR-4522	CLIP-seq
MIRT2369958	hsa-miR-4640-5p	CLIP-seq
MIRT2149821	hsa-miR-4646-5p	CLIP-seq
MIRT1497451	hsa-miR-4666-3p	CLIP-seq
MIRT2149822	hsa-miR-4692	CLIP-seq
MIRT2369959	hsa-miR-4726-5p	CLIP-seq
MIRT2149823	hsa-miR-4728-5p	CLIP-seq
MIRT2369960	hsa-miR-4731-3p	CLIP-seq
MIRT1497454	hsa-miR-4731-5p	CLIP-seq
MIRT2149824	hsa-miR-4742-5p	CLIP-seq
MIRT2369961	hsa-miR-4744	CLIP-seq
MIRT2369962	hsa-miR-4756-3p	CLIP-seq
MIRT2369963	hsa-miR-4772-3p	CLIP-seq
MIRT2149825	hsa-miR-4772-5p	CLIP-seq
MIRT2149827	hsa-miR-4790-3p	CLIP-seq
MIRT1497459	hsa-miR-4799-5p	CLIP-seq
MIRT2369964	hsa-miR-4801	CLIP-seq
MIRT1497461	hsa-miR-490-3p	CLIP-seq
MIRT2369965	hsa-miR-499-3p	CLIP-seq
MIRT2369966	hsa-miR-499a-3p	CLIP-seq
MIRT2369967	hsa-miR-513b	CLIP-seq
MIRT1497462	hsa-miR-520a-5p	CLIP-seq
MIRT1497463	hsa-miR-520d-5p	CLIP-seq
MIRT1497464	hsa-miR-524-5p	CLIP-seq
MIRT1497465	hsa-miR-525-5p	CLIP-seq
MIRT2149828	hsa-miR-526b	CLIP-seq
MIRT2369968	hsa-miR-548m	CLIP-seq
MIRT1497472	hsa-miR-567	CLIP-seq
MIRT2369969	hsa-miR-576-5p	CLIP-seq
MIRT2149829	hsa-miR-578	CLIP-seq
MIRT1497475	hsa-miR-630	CLIP-seq
MIRT1497477	hsa-miR-649	CLIP-seq
MIRT1497478	hsa-miR-664	CLIP-seq
MIRT2369970	hsa-miR-668	CLIP-seq
MIRT2149830	hsa-miR-765	CLIP-seq
MIRT2369971	hsa-miR-891b	CLIP-seq
MIRT1497396	hsa-miR-1281	CLIP-seq
MIRT1497398	hsa-miR-1323	CLIP-seq
MIRT2397109	hsa-miR-409-3p	CLIP-seq
MIRT1497447	hsa-miR-4454	CLIP-seq
MIRT1497452	hsa-miR-4666-5p	CLIP-seq
MIRT1497466	hsa-miR-548a-3p	CLIP-seq
MIRT1497468	hsa-miR-548e	CLIP-seq
MIRT1497469	hsa-miR-548f	CLIP-seq
MIRT1497470	hsa-miR-548g	CLIP-seq
MIRT1497471	hsa-miR-548o	CLIP-seq
MIRT1497481	hsa-miR-892a	CLIP-seq
MIRT1497434	hsa-miR-370	CLIP-seq
MIRT2149821	hsa-miR-4646-5p	CLIP-seq
MIRT1497454	hsa-miR-4731-5p	CLIP-seq
MIRT2149828	hsa-miR-526b	CLIP-seq
MIRT2149829	hsa-miR-578	CLIP-seq
MIRT1497390	hsa-miR-1224-3p	CLIP-seq
MIRT1497391	hsa-miR-1224-5p	CLIP-seq
MIRT1497393	hsa-miR-1260	CLIP-seq
MIRT1497394	hsa-miR-1260b	CLIP-seq
MIRT1497395	hsa-miR-1280	CLIP-seq
MIRT1497396	hsa-miR-1281	CLIP-seq
MIRT1497397	hsa-miR-1298	CLIP-seq
MIRT1497400	hsa-miR-140-3p	CLIP-seq
MIRT1497401	hsa-miR-1827	CLIP-seq
MIRT1497402	hsa-miR-186	CLIP-seq
MIRT1497403	hsa-miR-188-3p	CLIP-seq
MIRT1497404	hsa-miR-188-5p	CLIP-seq
MIRT1497405	hsa-miR-2054	CLIP-seq
MIRT1497406	hsa-miR-218	CLIP-seq
MIRT1497408	hsa-miR-297	CLIP-seq
MIRT1497409	hsa-miR-300	CLIP-seq
MIRT1497410	hsa-miR-31	CLIP-seq
MIRT1497412	hsa-miR-3123	CLIP-seq
MIRT1497414	hsa-miR-3127-3p	CLIP-seq
MIRT1497415	hsa-miR-3133	CLIP-seq
MIRT1497416	hsa-miR-3149	CLIP-seq
MIRT2663766	hsa-miR-3154	CLIP-seq
MIRT1497417	hsa-miR-3156-3p	CLIP-seq
MIRT1497418	hsa-miR-3156-5p	CLIP-seq
MIRT1497419	hsa-miR-3158-3p	CLIP-seq
MIRT2663767	hsa-miR-3174	CLIP-seq
MIRT1497420	hsa-miR-3179	CLIP-seq
MIRT1497421	hsa-miR-3180-5p	CLIP-seq
MIRT1497426	hsa-miR-330-3p	CLIP-seq
MIRT1497428	hsa-miR-340	CLIP-seq
MIRT1497430	hsa-miR-3667-5p	CLIP-seq
MIRT1497431	hsa-miR-3675-5p	CLIP-seq
MIRT1497432	hsa-miR-3680	CLIP-seq
MIRT1497433	hsa-miR-3692	CLIP-seq
MIRT2663768	hsa-miR-369-3p	CLIP-seq
MIRT1497434	hsa-miR-370	CLIP-seq
MIRT2663769	hsa-miR-374c	CLIP-seq
MIRT1497435	hsa-miR-380	CLIP-seq
MIRT1497436	hsa-miR-381	CLIP-seq
MIRT1497438	hsa-miR-3919	CLIP-seq
MIRT1497439	hsa-miR-3922-5p	CLIP-seq
MIRT2663770	hsa-miR-4264	CLIP-seq
MIRT1497442	hsa-miR-4286	CLIP-seq
MIRT1497443	hsa-miR-4311	CLIP-seq
MIRT2369953	hsa-miR-4328	CLIP-seq
MIRT2369954	hsa-miR-4420	CLIP-seq
MIRT1497445	hsa-miR-4422	CLIP-seq
MIRT1497447	hsa-miR-4454	CLIP-seq
MIRT2663771	hsa-miR-4493	CLIP-seq
MIRT1497448	hsa-miR-4495	CLIP-seq
MIRT1497449	hsa-miR-4522	CLIP-seq
MIRT2663772	hsa-miR-4536	CLIP-seq
MIRT2149821	hsa-miR-4646-5p	CLIP-seq
MIRT1497451	hsa-miR-4666-3p	CLIP-seq
MIRT1497453	hsa-miR-4720-3p	CLIP-seq
MIRT1497454	hsa-miR-4731-5p	CLIP-seq
MIRT1497455	hsa-miR-4751	CLIP-seq
MIRT2149826	hsa-miR-4780	CLIP-seq
MIRT1497457	hsa-miR-4786-5p	CLIP-seq
MIRT2149827	hsa-miR-4790-3p	CLIP-seq
MIRT2663773	hsa-miR-4797-3p	CLIP-seq
MIRT1497458	hsa-miR-4797-5p	CLIP-seq
MIRT1497459	hsa-miR-4799-5p	CLIP-seq
MIRT1497460	hsa-miR-4804-3p	CLIP-seq
MIRT1497461	hsa-miR-490-3p	CLIP-seq
MIRT2663774	hsa-miR-513a-3p	CLIP-seq
MIRT1497462	hsa-miR-520a-5p	CLIP-seq
MIRT1497463	hsa-miR-520d-5p	CLIP-seq
MIRT1497464	hsa-miR-524-5p	CLIP-seq
MIRT1497465	hsa-miR-525-5p	CLIP-seq
MIRT2149828	hsa-miR-526b	CLIP-seq
MIRT1497467	hsa-miR-548aa	CLIP-seq
MIRT1497472	hsa-miR-567	CLIP-seq
MIRT2149829	hsa-miR-578	CLIP-seq
MIRT1497474	hsa-miR-615-5p	CLIP-seq
MIRT1497475	hsa-miR-630	CLIP-seq
MIRT1497476	hsa-miR-643	CLIP-seq
MIRT1497477	hsa-miR-649	CLIP-seq
MIRT2663775	hsa-miR-655	CLIP-seq
MIRT1497478	hsa-miR-664	CLIP-seq
MIRT2369970	hsa-miR-668	CLIP-seq
MIRT1497479	hsa-miR-769-5p	CLIP-seq
MIRT1497390	hsa-miR-1224-3p	CLIP-seq
MIRT1497391	hsa-miR-1224-5p	CLIP-seq
MIRT1497393	hsa-miR-1260	CLIP-seq
MIRT1497394	hsa-miR-1260b	CLIP-seq
MIRT1497395	hsa-miR-1280	CLIP-seq
MIRT1497396	hsa-miR-1281	CLIP-seq
MIRT1497397	hsa-miR-1298	CLIP-seq
MIRT1497400	hsa-miR-140-3p	CLIP-seq
MIRT1497401	hsa-miR-1827	CLIP-seq
MIRT1497402	hsa-miR-186	CLIP-seq
MIRT1497403	hsa-miR-188-3p	CLIP-seq
MIRT1497404	hsa-miR-188-5p	CLIP-seq
MIRT1497405	hsa-miR-2054	CLIP-seq
MIRT1497406	hsa-miR-218	CLIP-seq
MIRT1497408	hsa-miR-297	CLIP-seq
MIRT1497409	hsa-miR-300	CLIP-seq
MIRT1497410	hsa-miR-31	CLIP-seq
MIRT1497412	hsa-miR-3123	CLIP-seq
MIRT1497414	hsa-miR-3127-3p	CLIP-seq
MIRT1497415	hsa-miR-3133	CLIP-seq
MIRT1497416	hsa-miR-3149	CLIP-seq
MIRT2663766	hsa-miR-3154	CLIP-seq
MIRT1497417	hsa-miR-3156-3p	CLIP-seq
MIRT1497418	hsa-miR-3156-5p	CLIP-seq
MIRT1497419	hsa-miR-3158-3p	CLIP-seq
MIRT1497420	hsa-miR-3179	CLIP-seq
MIRT1497421	hsa-miR-3180-5p	CLIP-seq
MIRT1497426	hsa-miR-330-3p	CLIP-seq
MIRT1497428	hsa-miR-340	CLIP-seq
MIRT1497430	hsa-miR-3667-5p	CLIP-seq
MIRT1497431	hsa-miR-3675-5p	CLIP-seq
MIRT1497432	hsa-miR-3680	CLIP-seq
MIRT1497433	hsa-miR-3692	CLIP-seq
MIRT2663768	hsa-miR-369-3p	CLIP-seq
MIRT1497434	hsa-miR-370	CLIP-seq
MIRT2663769	hsa-miR-374c	CLIP-seq
MIRT1497435	hsa-miR-380	CLIP-seq
MIRT1497436	hsa-miR-381	CLIP-seq
MIRT1497438	hsa-miR-3919	CLIP-seq
MIRT1497439	hsa-miR-3922-5p	CLIP-seq
MIRT1497442	hsa-miR-4286	CLIP-seq
MIRT1497443	hsa-miR-4311	CLIP-seq
MIRT2369954	hsa-miR-4420	CLIP-seq
MIRT1497445	hsa-miR-4422	CLIP-seq
MIRT1497447	hsa-miR-4454	CLIP-seq
MIRT2663771	hsa-miR-4493	CLIP-seq
MIRT1497448	hsa-miR-4495	CLIP-seq
MIRT1497449	hsa-miR-4522	CLIP-seq
MIRT2663772	hsa-miR-4536	CLIP-seq
MIRT2149821	hsa-miR-4646-5p	CLIP-seq
MIRT1497451	hsa-miR-4666-3p	CLIP-seq
MIRT1497453	hsa-miR-4720-3p	CLIP-seq
MIRT1497454	hsa-miR-4731-5p	CLIP-seq
MIRT1497455	hsa-miR-4751	CLIP-seq
MIRT2149826	hsa-miR-4780	CLIP-seq
MIRT1497457	hsa-miR-4786-5p	CLIP-seq
MIRT2149827	hsa-miR-4790-3p	CLIP-seq
MIRT1497458	hsa-miR-4797-5p	CLIP-seq
MIRT1497459	hsa-miR-4799-5p	CLIP-seq
MIRT1497460	hsa-miR-4804-3p	CLIP-seq
MIRT1497461	hsa-miR-490-3p	CLIP-seq
MIRT1497462	hsa-miR-520a-5p	CLIP-seq
MIRT1497463	hsa-miR-520d-5p	CLIP-seq
MIRT1497464	hsa-miR-524-5p	CLIP-seq
MIRT1497465	hsa-miR-525-5p	CLIP-seq
MIRT2149828	hsa-miR-526b	CLIP-seq
MIRT1497467	hsa-miR-548aa	CLIP-seq
MIRT1497472	hsa-miR-567	CLIP-seq
MIRT2149829	hsa-miR-578	CLIP-seq
MIRT1497474	hsa-miR-615-5p	CLIP-seq
MIRT1497475	hsa-miR-630	CLIP-seq
MIRT1497476	hsa-miR-643	CLIP-seq
MIRT1497477	hsa-miR-649	CLIP-seq
MIRT2663775	hsa-miR-655	CLIP-seq
MIRT1497478	hsa-miR-664	CLIP-seq
MIRT2369970	hsa-miR-668	CLIP-seq
MIRT1497479	hsa-miR-769-5p	CLIP-seq

Show/Hide all(78)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000723	Process	Telomere maintenance	IBA	21873635
GO:0000781	Component	Chromosome, telomeric region	HDA	19135898
GO:0000781	Component	Chromosome, telomeric region	IDA	10535943
GO:0000783	Component	Nuclear telomere cap complex	TAS	15100233
GO:0000976	Function	Transcription regulatory region sequence-specific DNA binding	IDA	18809223
GO:0002218	Process	Activation of innate immune response	IDA	28712728
GO:0003677	Function	DNA binding	NAS	1537839
GO:0003678	Function	DNA helicase activity	IEA
GO:0003684	Function	Damaged DNA binding	IEA
GO:0003690	Function	Double-stranded DNA binding	IBA	21873635
GO:0003691	Function	Double-stranded telomeric DNA binding	IDA	10409678
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IDA	14704337
GO:0005515	Function	Protein binding	IPI	8621488, 12145306, 12377759, 14704337, 15075319, 17159921, 17283121, 17308091, 17396150, 19142223, 19303849, 20023628, 20085707, 20098424, 20711232, 21070772, 21679440, 22451927, 22504299, 23178593, 23685356, 24485452, 24610814, 24981860, 25277244, 25574025, 25749521, 25852083, 2603
GO:0005524	Function	ATP binding	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005634	Component	Nucleus	IDA	32103174
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005730	Component	Nucleolus	IDA	32103174
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA
GO:0006302	Process	Double-strand break repair	IMP	19581589
GO:0006303	Process	Double-strand break repair via nonhomologous end joining	IBA	21873635
GO:0006303	Process	Double-strand break repair via nonhomologous end joining	IDA	26359349
GO:0006303	Process	Double-strand break repair via nonhomologous end joining	IMP	20383123
GO:0006303	Process	Double-strand break repair via nonhomologous end joining	TAS	15824061
GO:0006310	Process	DNA recombination	IEA
GO:0006974	Process	Cellular response to DNA damage stimulus	IMP	27248496
GO:0007420	Process	Brain development	IEA
GO:0008022	Function	Protein C-terminus binding	IPI	10783163
GO:0008047	Function	Enzyme activator activity	TAS	19188702
GO:0008094	Function	DNA-dependent ATPase activity	IDA	9368068
GO:0008283	Process	Cell population proliferation	IEA
GO:0016020	Component	Membrane	HDA	19946888
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	22266820
GO:0032040	Component	Small-subunit processome	IDA	32103174
GO:0032204	Process	Regulation of telomere maintenance	TAS	15824061, 18710952, 24095731
GO:0032212	Process	Positive regulation of telomere maintenance via telomerase	IMP	19188702
GO:0032481	Process	Positive regulation of type I interferon production	TAS
GO:0032508	Process	DNA duplex unwinding	IEA
GO:0032991	Component	Protein-containing complex	IDA	22504299
GO:0032993	Component	Protein-DNA complex	IDA	22504299
GO:0034462	Process	Small-subunit processome assembly	IDA	32103174
GO:0034511	Function	U3 snoRNA binding	IDA	32103174
GO:0034774	Component	Secretory granule lumen	TAS
GO:0042162	Function	Telomeric DNA binding	IBA	21873635
GO:0042162	Function	Telomeric DNA binding	IDA	10535943
GO:0042162	Function	Telomeric DNA binding	TAS	12377759
GO:0042493	Process	Response to drug	IEA
GO:0043085	Process	Positive regulation of catalytic activity	TAS	19188702
GO:0043312	Process	Neutrophil degranulation	TAS
GO:0043564	Component	Ku70:Ku80 complex	IBA	21873635
GO:0043564	Component	Ku70:Ku80 complex	IDA	20383123, 24095731, 26359349
GO:0043564	Component	Ku70:Ku80 complex	TAS	19188702
GO:0044877	Function	Protein-containing complex binding	IPI	12377759
GO:0045027	Function	DNA end binding	IDA	19549901
GO:0045027	Function	DNA end binding	IDA	9368068
GO:0045087	Process	Innate immune response	IEA
GO:0045860	Process	Positive regulation of protein kinase activity	IDA	22504299
GO:0045892	Process	Negative regulation of transcription, DNA-templated	IMP	8621488
GO:0048660	Process	Regulation of smooth muscle cell proliferation	IMP	25852083
GO:0050769	Process	Positive regulation of neurogenesis	IEA
GO:0051575	Function	5'-deoxyribose-5-phosphate lyase activity	IMP	20383123
GO:0051973	Process	Positive regulation of telomerase activity	TAS	19188702
GO:0060218	Process	Hematopoietic stem cell differentiation	IEA
GO:0070198	Process	Protein localization to chromosome, telomeric region	TAS	19188702
GO:0070419	Component	Nonhomologous end joining complex	IDA	20383123, 25941166
GO:0071398	Process	Cellular response to fatty acid	IEA
GO:0071475	Process	Cellular hyperosmotic salinity response	IEA
GO:0071480	Process	Cellular response to gamma radiation	IBA	21873635
GO:0071480	Process	Cellular response to gamma radiation	IDA	26359349
GO:0071481	Process	Cellular response to X-ray	IBA	21873635
GO:0075713	Process	Establishment of integrated proviral latency	TAS
GO:0090734	Component	Site of DNA damage	IMP	27248496
GO:1904430	Process	Negative regulation of t-circle formation	IMP	19581589
GO:1990830	Process	Cellular response to leukemia inhibitory factor	IEA
GO:1990904	Component	Ribonucleoprotein complex	IDA	14704337

MIM	HGNC	e!Ensembl
194364	12833	ENSG00000079246

Protein

UniProt ID

P13010

Protein name

X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC

Protein function

Single-stranded DNA-dependent ATP-dependent helicase that plays a key role in DNA non-homologous end joining (NHEJ) by recruiting DNA-PK to DNA (PubMed:11493912, PubMed:12145306, PubMed:7957065, PubMed:8621488). Required for double-strand break

PDB

1JEQ , 1JEY , 1Q2Z , 1RW2 , 3RZ9 , 5Y3R , 6ERF , 6ERG , 6ERH , 6ZH6 , 6ZHA , 6ZHE , 7AXZ , 7K0Y , 7K17 , 7K1J , 7K1K , 7K1N , 7LSY , 7LT3 , 7NFC , 7NFE , 7SGL , 7SU3 , 7SUD , 7Z6O , 7Z87 , 7Z88 , 7ZT6 , 7ZVT , 7ZWA , 7ZYG , 8AG4 , 8AG5 , 8ASC , 8BH3 , 8BHV , 8BHY , 8BOT , 8EZA , 8EZB , 8RD4

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF03731	Ku_N	9 → 244	Ku70/Ku80 N-terminal alpha/beta domain	Domain
PF02735	Ku	253 → 453	Ku70/Ku80 beta-barrel domain	Domain
PF03730	Ku_C	476 → 569	Ku70/Ku80 C-terminal arm	Family
PF08785	Ku_PK_bind	593 → 706	Ku C terminal domain like	Domain

Sequence

MVRSGNKAAVVLCMDVGFTMSNSIPGIESPFEQAKKVITMFVQRQVFAENKDEIALVLFG
TDGTDNPLSGGDQYQNITVHRHLMLPDFDLLEDIESKIQPGSQQADFLDALIVSMDVIQH
ETIGKKFEKRHIEIFTDLSSRFSKSQLDIIIHSLKKCDISLQFFLPFSLGKEDGSGDRGD
GPFRLGGHGPSFPLKGITEQQKEGLEIVKMVMISLEGEDGLDEIYSFSESLRKLCVFKKI
ERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDD
DETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQ
VLKVFAARDDEAAAVALSSLIHALDDLDMVAIVRYAYDKRANPQVGVAFPHIKHNYECLV
YVQLPFMEDLRQYMFSSLKNSKKYAPTEAQLNAVDALIDSMSLAKKDEKTDTLEDLFPTT
KIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTTKSQIPLSKIKTLFPLI
EAKKKDQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSLAEGSVTSVGSVNPAENFRV
LVKQKKASFEEASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLK
ALQEKVEIKQLNHFWEIVVQDGITLITKEEASGSSVTAEEAKKFLAPKDKPSGDTAAVFE
EGGDVDDLLDMI

Sequence length

732

Interactions

View interactions

	KEGG		Reactome
	Non-homologous end-joining		2-LTR circle formation Cytosolic sensors of pathogen-associated DNA IRF3-mediated induction of type I IFN Nonhomologous End-Joining (NHEJ) Neutrophil degranulation

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Lung adenocarcinoma	Adenocarcinoma of lung (disorder)	rs28934576, rs121913530, rs397516975, rs587776805, rs121913469, rs121913364, rs121913351, rs121913366, rs397516896, rs397516977, rs397516981, rs397517127, rs121913344, rs727504233, rs121913370 View all (5 more)	27602772

Show/Hide Text Mining Associations (77)

Disease Name	Relationship Type	References
Associations from Text Mining
Acquired Immunodeficiency Syndrome	Associate	36312587
Adenocarcinoma of Lung	Associate	23181744, 28399858, 34486486
Adenomatous Polyposis Coli	Associate	39519399
Arthritis Rheumatoid	Associate	36835215
Astrocytoma	Associate	27852033
Ataxia Telangiectasia	Associate	9636207
Breast Neoplasms	Associate	10823943, 20044645, 24062231, 25501155, 29133620, 32501811, 33734613, 37429610
Carcinogenesis	Associate	12324457, 18403903, 26918347
Carcinoma Basal Cell	Associate	16497868
Carcinoma Hepatocellular	Associate	21410269, 24020493, 30897324, 31599408, 32258128, 35903292
Carcinoma Hepatocellular	Stimulate	33006365
Carcinoma Non Small Cell Lung	Associate	31727206
Carcinoma Renal Cell	Associate	25902193
Carcinoma Squamous Cell	Associate	22921042
Colorectal Neoplasms	Associate	11792868, 19528488
Colorectal Neoplasms	Inhibit	19177010, 20689513
Death	Associate	21349997
DNA Virus Infections	Associate	25690937, 27098276, 28698766, 36640924
Drug Related Side Effects and Adverse Reactions	Associate	26358256
Endometriosis	Stimulate	26059197
Esophageal Neoplasms	Associate	18403903
Esophageal Squamous Cell Carcinoma	Associate	18403903, 25758053
Familial medullary thyroid carcinoma	Associate	26870890
Fanconi Anemia	Associate	11124945
Fever	Inhibit	25902193
GATA2 Deficiency	Associate	34761614
Genetic Predisposition to Disease	Associate	22404984
Glioblastoma	Associate	15133290
Glioma	Associate	26464705, 34076980
Head and Neck Neoplasms	Associate	21877955
Hematologic Diseases	Associate	26358256
Hepatolenticular Degeneration	Associate	11985593
HTLV I Infections	Associate	26360636
Hypoxia Brain	Inhibit	22903042
Idiopathic Noncirrhotic Portal Hypertension	Associate	24020493
Leukemia Lymphocytic Chronic B Cell	Associate	15718417
Leukemia Lymphocytic Chronic B Cell	Inhibit	18077792
Leukemia Myelogenous Chronic BCR ABL Positive	Associate	23982877
Liver Cirrhosis	Associate	24020493
Liver Diseases Alcoholic	Associate	24020493
Lown Ganong Levine Syndrome	Associate	33734613
Lung Neoplasms	Associate	24744142, 26358256, 26918347
Lymphatic Metastasis	Associate	25758053
Lymphoma Large B Cell Diffuse	Associate	23960188
Lymphoma Primary Effusion	Associate	25860939
Lymphoma T Cell Cutaneous	Associate	20408834
Malformations of Cortical Development Group I	Associate	12867423
Mouth Neoplasms	Associate	16827151
Multiple Myeloma	Associate	11086072, 11882358, 11985783, 19652854
Muscular Diseases	Associate	28025995
Myelodysplastic Syndromes	Associate	27497341
Nasopharyngeal Carcinoma	Associate	36107539
Neoplasm Metastasis	Associate	31599408, 34076980
Neoplasms	Associate	11086072, 11104569, 11882358, 12216085, 16497868, 16685270, 16827151, 18403903, 20689513, 21877955, 22348039, 23621240, 23960188, 23982877, 24744142 View all (6 more)
Neoplasms	Stimulate	16425368, 19672258, 21349997
Neoplasms Basal Cell	Associate	26059197
Neuroblastoma	Associate	36445966
Osteosarcoma	Associate	23621240
Ovarian Neoplasms	Stimulate	26059197
Pancreatic Neoplasms	Associate	24744142
Prostatic Neoplasms	Associate	29179998
Pulmonary Disease Chronic Obstructive	Associate	20463177, 24615081
Radiation Injuries	Associate	23697595
Radiation Pneumonitis	Associate	21717429
Renal Insufficiency	Stimulate	21349997
Skin Neoplasms	Associate	16497868
Squamous Cell Carcinoma of Head and Neck	Associate	21349997, 39478631
Stomach Diseases	Associate	12324457
Stomach Neoplasms	Associate	12324457, 21547134, 24187467, 25527410
Thyroid cancer medullary	Associate	26870890
Thyroid Cancer Papillary	Associate	31578590
Thyroid Neoplasms	Stimulate	31578590
Thyroiditis	Associate	26870890
Triple Negative Breast Neoplasms	Associate	33734613
Urinary Bladder Neoplasms	Associate	19414375, 23302228, 23932191
Uterine Cervical Neoplasms	Associate	19672258
Venous Thrombosis	Associate	32915819

XRCC5 (X-ray repair cross complementing 5)