Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	7517
Gene name	X-ray repair cross complementing 3
Gene symbol	XRCC3
Synonyms (NCBI Gene)	CMM6
Chromosome	14
Chromosome location	14q32.33
Summary	This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant

468

Show/Hide all (468)

miRTarBase ID	miRNA	Experiments	Reference
MIRT514560	hsa-miR-548aa	HITS-CLIP	21572407
MIRT514559	hsa-miR-548ap-3p	HITS-CLIP	21572407
MIRT514558	hsa-miR-548t-3p	HITS-CLIP	21572407
MIRT503293	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT707104	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT503292	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT508307	hsa-miR-511-3p	HITS-CLIP	21572407
MIRT508306	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT508305	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT503291	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT503290	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT508304	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT503293	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT503292	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT508307	hsa-miR-511-3p	HITS-CLIP	21572407
MIRT508306	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT508305	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT503291	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT503290	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT508304	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT503293	hsa-miR-5580-3p	HITS-CLIP	23313552
MIRT503292	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT503291	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT503290	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT609260	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT609259	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT609258	hsa-miR-4514	HITS-CLIP	23824327
MIRT609257	hsa-miR-4692	HITS-CLIP	23824327
MIRT609256	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT609255	hsa-miR-4673	HITS-CLIP	23824327
MIRT609254	hsa-miR-6075	HITS-CLIP	23824327
MIRT609260	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT609259	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT609258	hsa-miR-4514	HITS-CLIP	23824327
MIRT609257	hsa-miR-4692	HITS-CLIP	23824327
MIRT609256	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT609255	hsa-miR-4673	HITS-CLIP	23824327
MIRT609254	hsa-miR-6075	HITS-CLIP	23824327
MIRT609260	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT609259	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT609258	hsa-miR-4514	HITS-CLIP	23824327
MIRT609257	hsa-miR-4692	HITS-CLIP	23824327
MIRT609256	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT609255	hsa-miR-4673	HITS-CLIP	23824327
MIRT609254	hsa-miR-6075	HITS-CLIP	23824327
MIRT613421	hsa-miR-548an	HITS-CLIP	23824327
MIRT613420	hsa-miR-6768-3p	HITS-CLIP	23824327
MIRT613419	hsa-miR-4484	HITS-CLIP	23824327
MIRT609260	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT609259	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT609258	hsa-miR-4514	HITS-CLIP	23824327
MIRT609257	hsa-miR-4692	HITS-CLIP	23824327
MIRT609256	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT609255	hsa-miR-4673	HITS-CLIP	23824327
MIRT609254	hsa-miR-6075	HITS-CLIP	23824327
MIRT609260	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT609259	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT609258	hsa-miR-4514	HITS-CLIP	23824327
MIRT609257	hsa-miR-4692	HITS-CLIP	23824327
MIRT609256	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT609255	hsa-miR-4673	HITS-CLIP	23824327
MIRT609254	hsa-miR-6075	HITS-CLIP	23824327
MIRT514565	hsa-miR-548ac	PAR-CLIP	21572407
MIRT514564	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT514563	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT514562	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT514561	hsa-miR-548z	PAR-CLIP	21572407
MIRT514560	hsa-miR-548aa	PAR-CLIP	21572407
MIRT514559	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT514558	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT503293	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT503292	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT508307	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT508306	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT508305	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT503291	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT503290	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT508304	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT514565	hsa-miR-548ac	PAR-CLIP	21572407
MIRT514564	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT514563	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT514562	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT514561	hsa-miR-548z	PAR-CLIP	21572407
MIRT514560	hsa-miR-548aa	PAR-CLIP	21572407
MIRT514559	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT514558	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT503292	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT508307	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT508306	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT508305	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT503291	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT503290	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT508304	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT503293	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT503292	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT508307	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT508306	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT508305	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT503291	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT503290	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT508304	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT514565	hsa-miR-548ac	PAR-CLIP	23446348
MIRT514564	hsa-miR-548bb-3p	PAR-CLIP	23446348
MIRT514563	hsa-miR-548d-3p	PAR-CLIP	23446348
MIRT514562	hsa-miR-548h-3p	PAR-CLIP	23446348
MIRT514561	hsa-miR-548z	PAR-CLIP	23446348
MIRT514560	hsa-miR-548aa	PAR-CLIP	23446348
MIRT514559	hsa-miR-548ap-3p	PAR-CLIP	23446348
MIRT514558	hsa-miR-548t-3p	PAR-CLIP	23446348
MIRT503293	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT503292	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT508307	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT508306	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT508305	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT503291	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT503290	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT508304	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT503292	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT508307	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT508306	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT508305	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT503291	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT503290	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT508304	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT503293	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT503292	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT503291	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT503290	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT482713	hsa-miR-1295b-5p	PAR-CLIP	23592263
MIRT482712	hsa-miR-1912	PAR-CLIP	23592263
MIRT114265	hsa-miR-6746-3p	PAR-CLIP	23592263
MIRT482711	hsa-miR-4257	PAR-CLIP	23592263
MIRT482710	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT482709	hsa-miR-4784	PAR-CLIP	23592263
MIRT482707	hsa-miR-6134	PAR-CLIP	23592263
MIRT482708	hsa-miR-765	PAR-CLIP	23592263
MIRT482706	hsa-miR-4710	PAR-CLIP	23592263
MIRT482705	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT482704	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT482703	hsa-miR-6748-5p	PAR-CLIP	23592263
MIRT482702	hsa-miR-4689	PAR-CLIP	23592263
MIRT482701	hsa-miR-6858-5p	PAR-CLIP	23592263
MIRT482700	hsa-miR-1262	PAR-CLIP	23592263
MIRT482699	hsa-miR-4701-3p	PAR-CLIP	23592263
MIRT482697	hsa-miR-6736-5p	PAR-CLIP	23592263
MIRT482698	hsa-miR-4651	PAR-CLIP	23592263
MIRT482713	hsa-miR-1295b-5p	PAR-CLIP	23592263
MIRT482712	hsa-miR-1912	PAR-CLIP	23592263
MIRT114265	hsa-miR-6746-3p	PAR-CLIP	23592263
MIRT482711	hsa-miR-4257	PAR-CLIP	23592263
MIRT482710	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT482709	hsa-miR-4784	PAR-CLIP	23592263
MIRT482707	hsa-miR-6134	PAR-CLIP	23592263
MIRT482708	hsa-miR-765	PAR-CLIP	23592263
MIRT482706	hsa-miR-4710	PAR-CLIP	23592263
MIRT482705	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT482704	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT482703	hsa-miR-6748-5p	PAR-CLIP	23592263
MIRT482702	hsa-miR-4689	PAR-CLIP	23592263
MIRT482701	hsa-miR-6858-5p	PAR-CLIP	23592263
MIRT482700	hsa-miR-1262	PAR-CLIP	23592263
MIRT482699	hsa-miR-4701-3p	PAR-CLIP	23592263
MIRT482697	hsa-miR-6736-5p	PAR-CLIP	23592263
MIRT482698	hsa-miR-4651	PAR-CLIP	23592263
MIRT514560	hsa-miR-548aa	HITS-CLIP	21572407
MIRT514559	hsa-miR-548ap-3p	HITS-CLIP	21572407
MIRT514558	hsa-miR-548t-3p	HITS-CLIP	21572407
MIRT503293	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT707104	hsa-miR-410-3p	HITS-CLIP	21572407
MIRT503292	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT508307	hsa-miR-511-3p	HITS-CLIP	21572407
MIRT508306	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT508305	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT503291	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT503290	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT508304	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT503293	hsa-miR-5580-3p	HITS-CLIP	21572407
MIRT503292	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT508307	hsa-miR-511-3p	HITS-CLIP	21572407
MIRT508306	hsa-miR-223-5p	HITS-CLIP	21572407
MIRT508305	hsa-miR-6867-5p	HITS-CLIP	21572407
MIRT503291	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT503290	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT508304	hsa-miR-574-5p	HITS-CLIP	21572407
MIRT503293	hsa-miR-5580-3p	HITS-CLIP	23313552
MIRT503292	hsa-miR-5011-5p	HITS-CLIP	23313552
MIRT503291	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT503290	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT609260	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT609259	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT609258	hsa-miR-4514	HITS-CLIP	23824327
MIRT609257	hsa-miR-4692	HITS-CLIP	23824327
MIRT609256	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT609255	hsa-miR-4673	HITS-CLIP	23824327
MIRT609254	hsa-miR-6075	HITS-CLIP	23824327
MIRT609260	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT609259	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT609258	hsa-miR-4514	HITS-CLIP	23824327
MIRT609257	hsa-miR-4692	HITS-CLIP	23824327
MIRT609256	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT609255	hsa-miR-4673	HITS-CLIP	23824327
MIRT609254	hsa-miR-6075	HITS-CLIP	23824327
MIRT609260	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT609259	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT609258	hsa-miR-4514	HITS-CLIP	23824327
MIRT609257	hsa-miR-4692	HITS-CLIP	23824327
MIRT609256	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT609255	hsa-miR-4673	HITS-CLIP	23824327
MIRT609254	hsa-miR-6075	HITS-CLIP	23824327
MIRT613421	hsa-miR-548an	HITS-CLIP	23824327
MIRT613420	hsa-miR-6768-3p	HITS-CLIP	23824327
MIRT613419	hsa-miR-4484	HITS-CLIP	23824327
MIRT609260	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT609259	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT609258	hsa-miR-4514	HITS-CLIP	23824327
MIRT609257	hsa-miR-4692	HITS-CLIP	23824327
MIRT609256	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT609255	hsa-miR-4673	HITS-CLIP	23824327
MIRT609254	hsa-miR-6075	HITS-CLIP	23824327
MIRT609260	hsa-miR-1910-3p	HITS-CLIP	23824327
MIRT609259	hsa-miR-6511a-5p	HITS-CLIP	23824327
MIRT609258	hsa-miR-4514	HITS-CLIP	23824327
MIRT609257	hsa-miR-4692	HITS-CLIP	23824327
MIRT609256	hsa-miR-4645-5p	HITS-CLIP	23824327
MIRT609255	hsa-miR-4673	HITS-CLIP	23824327
MIRT609254	hsa-miR-6075	HITS-CLIP	23824327
MIRT514565	hsa-miR-548ac	PAR-CLIP	21572407
MIRT514564	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT514563	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT514562	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT514561	hsa-miR-548z	PAR-CLIP	21572407
MIRT514560	hsa-miR-548aa	PAR-CLIP	21572407
MIRT514559	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT514558	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT503293	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT503292	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT508307	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT508306	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT508305	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT503291	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT503290	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT508304	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT514565	hsa-miR-548ac	PAR-CLIP	21572407
MIRT514564	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT514563	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT514562	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT514561	hsa-miR-548z	PAR-CLIP	21572407
MIRT514560	hsa-miR-548aa	PAR-CLIP	21572407
MIRT514559	hsa-miR-548ap-3p	PAR-CLIP	21572407
MIRT514558	hsa-miR-548t-3p	PAR-CLIP	21572407
MIRT503292	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT508307	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT508306	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT508305	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT503291	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT503290	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT508304	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT503293	hsa-miR-5580-3p	PAR-CLIP	21572407
MIRT503292	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT508307	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT508306	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT508305	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT503291	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT503290	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT508304	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT514565	hsa-miR-548ac	PAR-CLIP	23446348
MIRT514564	hsa-miR-548bb-3p	PAR-CLIP	23446348
MIRT514563	hsa-miR-548d-3p	PAR-CLIP	23446348
MIRT514562	hsa-miR-548h-3p	PAR-CLIP	23446348
MIRT514561	hsa-miR-548z	PAR-CLIP	23446348
MIRT514560	hsa-miR-548aa	PAR-CLIP	23446348
MIRT514559	hsa-miR-548ap-3p	PAR-CLIP	23446348
MIRT514558	hsa-miR-548t-3p	PAR-CLIP	23446348
MIRT503293	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT503292	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT508307	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT508306	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT508305	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT503291	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT503290	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT508304	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT503292	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT508307	hsa-miR-511-3p	PAR-CLIP	23446348
MIRT508306	hsa-miR-223-5p	PAR-CLIP	23446348
MIRT508305	hsa-miR-6867-5p	PAR-CLIP	23446348
MIRT503291	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT503290	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT508304	hsa-miR-574-5p	PAR-CLIP	23446348
MIRT503293	hsa-miR-5580-3p	PAR-CLIP	23446348
MIRT503292	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT503291	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT503290	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT482713	hsa-miR-1295b-5p	PAR-CLIP	23592263
MIRT482712	hsa-miR-1912	PAR-CLIP	23592263
MIRT114265	hsa-miR-6746-3p	PAR-CLIP	23592263
MIRT482711	hsa-miR-4257	PAR-CLIP	23592263
MIRT482710	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT482709	hsa-miR-4784	PAR-CLIP	23592263
MIRT482707	hsa-miR-6134	PAR-CLIP	23592263
MIRT482708	hsa-miR-765	PAR-CLIP	23592263
MIRT482706	hsa-miR-4710	PAR-CLIP	23592263
MIRT482705	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT482704	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT482703	hsa-miR-6748-5p	PAR-CLIP	23592263
MIRT482702	hsa-miR-4689	PAR-CLIP	23592263
MIRT482701	hsa-miR-6858-5p	PAR-CLIP	23592263
MIRT482700	hsa-miR-1262	PAR-CLIP	23592263
MIRT482699	hsa-miR-4701-3p	PAR-CLIP	23592263
MIRT482697	hsa-miR-6736-5p	PAR-CLIP	23592263
MIRT482698	hsa-miR-4651	PAR-CLIP	23592263
MIRT482713	hsa-miR-1295b-5p	PAR-CLIP	23592263
MIRT482712	hsa-miR-1912	PAR-CLIP	23592263
MIRT114265	hsa-miR-6746-3p	PAR-CLIP	23592263
MIRT482711	hsa-miR-4257	PAR-CLIP	23592263
MIRT482710	hsa-miR-3150b-3p	PAR-CLIP	23592263
MIRT482709	hsa-miR-4784	PAR-CLIP	23592263
MIRT482707	hsa-miR-6134	PAR-CLIP	23592263
MIRT482708	hsa-miR-765	PAR-CLIP	23592263
MIRT482706	hsa-miR-4710	PAR-CLIP	23592263
MIRT482705	hsa-miR-6769a-5p	PAR-CLIP	23592263
MIRT482704	hsa-miR-6769b-5p	PAR-CLIP	23592263
MIRT482703	hsa-miR-6748-5p	PAR-CLIP	23592263
MIRT482702	hsa-miR-4689	PAR-CLIP	23592263
MIRT482701	hsa-miR-6858-5p	PAR-CLIP	23592263
MIRT482700	hsa-miR-1262	PAR-CLIP	23592263
MIRT482699	hsa-miR-4701-3p	PAR-CLIP	23592263
MIRT482697	hsa-miR-6736-5p	PAR-CLIP	23592263
MIRT482698	hsa-miR-4651	PAR-CLIP	23592263
MIRT755773	hsa-miR-4796-3p	Luciferase reporter assayWestern blottingqRT-PCRin vitro cullelar assaysGFP reporter assay	37460775
MIRT1497320	hsa-miR-1183	CLIP-seq
MIRT1497321	hsa-miR-1197	CLIP-seq
MIRT1497322	hsa-miR-1208	CLIP-seq
MIRT1497323	hsa-miR-125a-5p	CLIP-seq
MIRT1497324	hsa-miR-125b	CLIP-seq
MIRT1497325	hsa-miR-1275	CLIP-seq
MIRT1497326	hsa-miR-1286	CLIP-seq
MIRT1497327	hsa-miR-1288	CLIP-seq
MIRT1497328	hsa-miR-146b-3p	CLIP-seq
MIRT1497329	hsa-miR-1827	CLIP-seq
MIRT1497330	hsa-miR-1915	CLIP-seq
MIRT1497331	hsa-miR-214	CLIP-seq
MIRT1497332	hsa-miR-3144-5p	CLIP-seq
MIRT1497333	hsa-miR-3155	CLIP-seq
MIRT1497334	hsa-miR-3155b	CLIP-seq
MIRT1497335	hsa-miR-3169	CLIP-seq
MIRT1497336	hsa-miR-3173-5p	CLIP-seq
MIRT1497337	hsa-miR-3175	CLIP-seq
MIRT1497338	hsa-miR-3180-5p	CLIP-seq
MIRT1497339	hsa-miR-3185	CLIP-seq
MIRT1497340	hsa-miR-3191	CLIP-seq
MIRT1497341	hsa-miR-3613-5p	CLIP-seq
MIRT1497342	hsa-miR-361-3p	CLIP-seq
MIRT1497343	hsa-miR-3619-5p	CLIP-seq
MIRT1497344	hsa-miR-3677-3p	CLIP-seq
MIRT1497345	hsa-miR-3937	CLIP-seq
MIRT1497346	hsa-miR-3944-5p	CLIP-seq
MIRT1497347	hsa-miR-4251	CLIP-seq
MIRT1497348	hsa-miR-4267	CLIP-seq
MIRT1497349	hsa-miR-4270	CLIP-seq
MIRT1497350	hsa-miR-4291	CLIP-seq
MIRT1497351	hsa-miR-4319	CLIP-seq
MIRT1497352	hsa-miR-4324	CLIP-seq
MIRT1497353	hsa-miR-4441	CLIP-seq
MIRT1497354	hsa-miR-4447	CLIP-seq
MIRT1497355	hsa-miR-4459	CLIP-seq
MIRT1497356	hsa-miR-4472	CLIP-seq
MIRT1497357	hsa-miR-4481	CLIP-seq
MIRT1497358	hsa-miR-4519	CLIP-seq
MIRT1497359	hsa-miR-4525	CLIP-seq
MIRT1497360	hsa-miR-4640-5p	CLIP-seq
MIRT1497361	hsa-miR-4652-5p	CLIP-seq
MIRT1497362	hsa-miR-4655-3p	CLIP-seq
MIRT1497363	hsa-miR-4665-5p	CLIP-seq
MIRT1497364	hsa-miR-4690-5p	CLIP-seq
MIRT1497365	hsa-miR-4722-5p	CLIP-seq
MIRT1497366	hsa-miR-4723-5p	CLIP-seq
MIRT1497367	hsa-miR-4726-3p	CLIP-seq
MIRT1497368	hsa-miR-4726-5p	CLIP-seq
MIRT1497369	hsa-miR-4745-5p	CLIP-seq
MIRT1497370	hsa-miR-4753-5p	CLIP-seq
MIRT1497371	hsa-miR-4758-5p	CLIP-seq
MIRT1497372	hsa-miR-4779	CLIP-seq
MIRT1497373	hsa-miR-484	CLIP-seq
MIRT1497374	hsa-miR-491-5p	CLIP-seq
MIRT1497375	hsa-miR-541	CLIP-seq
MIRT1497376	hsa-miR-564	CLIP-seq
MIRT1497377	hsa-miR-580	CLIP-seq
MIRT1497378	hsa-miR-608	CLIP-seq
MIRT1497379	hsa-miR-625	CLIP-seq
MIRT1497380	hsa-miR-654-5p	CLIP-seq
MIRT1497381	hsa-miR-761	CLIP-seq
MIRT1497382	hsa-miR-766	CLIP-seq
MIRT1497383	hsa-miR-874	CLIP-seq
MIRT1497384	hsa-miR-922	CLIP-seq
MIRT2149779	hsa-miR-1225-3p	CLIP-seq
MIRT2149780	hsa-miR-128	CLIP-seq
MIRT1497326	hsa-miR-1286	CLIP-seq
MIRT1497328	hsa-miR-146b-3p	CLIP-seq
MIRT2149781	hsa-miR-3117-5p	CLIP-seq
MIRT2149782	hsa-miR-3151	CLIP-seq
MIRT1497336	hsa-miR-3173-5p	CLIP-seq
MIRT2149783	hsa-miR-3199	CLIP-seq
MIRT2149784	hsa-miR-3201	CLIP-seq
MIRT2149785	hsa-miR-3612	CLIP-seq
MIRT2149786	hsa-miR-3689d	CLIP-seq
MIRT1497346	hsa-miR-3944-5p	CLIP-seq
MIRT1497347	hsa-miR-4251	CLIP-seq
MIRT2149787	hsa-miR-4302	CLIP-seq
MIRT1497352	hsa-miR-4324	CLIP-seq
MIRT2149788	hsa-miR-4443	CLIP-seq
MIRT1497354	hsa-miR-4447	CLIP-seq
MIRT1497355	hsa-miR-4459	CLIP-seq
MIRT1497356	hsa-miR-4472	CLIP-seq
MIRT1497357	hsa-miR-4481	CLIP-seq
MIRT2149789	hsa-miR-4491	CLIP-seq
MIRT2149790	hsa-miR-4508	CLIP-seq
MIRT2149791	hsa-miR-4515	CLIP-seq
MIRT2149792	hsa-miR-4527	CLIP-seq
MIRT2149793	hsa-miR-4648	CLIP-seq
MIRT2149794	hsa-miR-4654	CLIP-seq
MIRT2149795	hsa-miR-4657	CLIP-seq
MIRT2149796	hsa-miR-4701-5p	CLIP-seq
MIRT1497365	hsa-miR-4722-5p	CLIP-seq
MIRT1497369	hsa-miR-4745-5p	CLIP-seq
MIRT1497371	hsa-miR-4758-5p	CLIP-seq
MIRT2149797	hsa-miR-4769-5p	CLIP-seq
MIRT1497372	hsa-miR-4779	CLIP-seq
MIRT2149798	hsa-miR-4791	CLIP-seq
MIRT1497374	hsa-miR-491-5p	CLIP-seq
MIRT1497375	hsa-miR-541	CLIP-seq
MIRT1497377	hsa-miR-580	CLIP-seq
MIRT2149799	hsa-miR-588	CLIP-seq
MIRT1497378	hsa-miR-608	CLIP-seq
MIRT2149800	hsa-miR-615-3p	CLIP-seq
MIRT2149801	hsa-miR-650	CLIP-seq
MIRT1497380	hsa-miR-654-5p	CLIP-seq
MIRT2149802	hsa-miR-663b	CLIP-seq
MIRT1497330	hsa-miR-1915	CLIP-seq
MIRT2369948	hsa-miR-3160-5p	CLIP-seq
MIRT2149796	hsa-miR-4701-5p	CLIP-seq
MIRT2149799	hsa-miR-588	CLIP-seq
MIRT2149780	hsa-miR-128	CLIP-seq
MIRT2463617	hsa-miR-140-3p	CLIP-seq
MIRT2463618	hsa-miR-2113	CLIP-seq
MIRT2463619	hsa-miR-2682	CLIP-seq
MIRT2463620	hsa-miR-296-5p	CLIP-seq
MIRT2149781	hsa-miR-3117-5p	CLIP-seq
MIRT2149782	hsa-miR-3151	CLIP-seq
MIRT2369948	hsa-miR-3160-5p	CLIP-seq
MIRT2149784	hsa-miR-3201	CLIP-seq
MIRT2149786	hsa-miR-3689d	CLIP-seq
MIRT2463621	hsa-miR-3714	CLIP-seq
MIRT2463622	hsa-miR-4265	CLIP-seq
MIRT2463623	hsa-miR-4296	CLIP-seq
MIRT2149787	hsa-miR-4302	CLIP-seq
MIRT2463624	hsa-miR-4322	CLIP-seq
MIRT1497354	hsa-miR-4447	CLIP-seq
MIRT1497356	hsa-miR-4472	CLIP-seq
MIRT2463625	hsa-miR-449c	CLIP-seq
MIRT2149794	hsa-miR-4654	CLIP-seq
MIRT2463626	hsa-miR-4670-3p	CLIP-seq
MIRT2149797	hsa-miR-4769-5p	CLIP-seq
MIRT2149798	hsa-miR-4791	CLIP-seq
MIRT2463627	hsa-miR-486-3p	CLIP-seq
MIRT1497374	hsa-miR-491-5p	CLIP-seq
MIRT2463628	hsa-miR-515-5p	CLIP-seq
MIRT1497375	hsa-miR-541	CLIP-seq
MIRT1497380	hsa-miR-654-5p	CLIP-seq

Show/Hide all (45)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000400	Function	Four-way junction DNA binding	IBA
GO:0000400	Function	Four-way junction DNA binding	IDA	20207730
GO:0000722	Process	Telomere maintenance via recombination	IBA
GO:0000722	Process	Telomere maintenance via recombination	IMP	15507207
GO:0000724	Process	Double-strand break repair via homologous recombination	IMP	23149936
GO:0000781	Component	Chromosome, telomeric region	IC	15507207
GO:0003677	Function	DNA binding	IEA
GO:0005515	Function	Protein binding	IPI	9469824, 9660962, 11751635, 11842113, 21965664, 24005329, 24141787, 26496610, 28864920, 34591612
GO:0005524	Function	ATP binding	IEA
GO:0005634	Component	Nucleus	IDA	16215984, 26323318
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005657	Component	Replication fork	IBA
GO:0005657	Component	Replication fork	IDA	20207730
GO:0005737	Component	Cytoplasm	IDA	16215984
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	IDA	20413593
GO:0005739	Component	Mitochondrion	IEA
GO:0005829	Component	Cytosol	IDA
GO:0006281	Process	DNA repair	IEA
GO:0006281	Process	DNA repair	IGI	10422536
GO:0006281	Process	DNA repair	TAS	9660962
GO:0006310	Process	DNA recombination	IEA
GO:0006310	Process	DNA recombination	TAS	9660962
GO:0006974	Process	DNA damage response	IEA
GO:0006974	Process	DNA damage response	TAS	7603995
GO:0008821	Function	Crossover junction DNA endonuclease activity	IMP	14716019, 23108668
GO:0010824	Process	Regulation of centrosome duplication	IMP	23108668
GO:0033065	Component	Rad51C-XRCC3 complex	IBA
GO:0033065	Component	Rad51C-XRCC3 complex	IDA	11751635
GO:0036297	Process	Interstrand cross-link repair	IMP	26323318
GO:0045003	Process	Double-strand break repair via synthesis-dependent strand annealing	IBA
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	16215984
GO:0048471	Component	Perinuclear region of cytoplasm	IEA
GO:0071140	Process	Resolution of mitotic recombination intermediates	IBA
GO:0071140	Process	Resolution of mitotic recombination intermediates	IMP	23108668
GO:0090267	Process	Positive regulation of mitotic cell cycle spindle assembly checkpoint	IMP	23108668
GO:0090656	Process	T-circle formation	IBA
GO:0090656	Process	T-circle formation	IC	15507207
GO:0090656	Process	T-circle formation	IMP	21903669
GO:0090657	Process	Telomeric loop disassembly	TAS	27918544
GO:0090737	Process	Telomere maintenance via telomere trimming	IGI	27918544
GO:0140664	Function	ATP-dependent DNA damage sensor activity	IEA

MIM	HGNC	e!Ensembl
600675	12830	ENSG00000126215

O43542

Protein name

DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3)

Protein function

Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Part of the RAD51 paralog protein complex CX3 which acts in the BRCA1-BRCA2-dependen

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF08423	Rad51	52 → 340	Rad51	Domain

Sequence

MDLDLLDLNPRIIAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHLRGS
SILTALQLHQQKERFPTQHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQL
CLAVQFPRQHGGLEAGAVYICTEDAFPHKRLQQLMAQQPRLRTDVPGELLQKLRFGSQIF
IEHVADVDTLLECVNKKVPVLLSRGMARLVVIDSVAAPFRCEFDSQASAPRARHLQSLGA
TLRELSSAFQSPVLCINQVTEAMEEQGAAHGPLGFWDERVSPALGITWANQLLVRLLADR
LREEEAALGCPARTLRVLSAPHLPPSSCSYTISAEGVRGTPGTQSH

Sequence length

346

Interactions

View interactions

	KEGG		Reactome
	Homologous recombination		HDR through Homologous Recombination (HRR) Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Resolution of D-loop Structures through Holliday Junction Intermediates Homologous DNA Pairing and Strand Exchange

Show/Hide Unknown Diseases (5)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Breast cancer, susceptibility to	risk factor	rs1799796	RCV000009501
Familial cancer of breast	Uncertain significance	rs753750563	RCV003225795
Melanoma, cutaneous malignant, susceptibility to, 6	Benign	rs861539	RCV000009500
Ovarian cancer	Benign	rs532124840, rs28903080, rs141201371	RCV003154011 RCV003154686 RCV003154819
XRCC3-related disorder	Benign; Likely benign	rs861539, rs28903081, rs374168537, rs56347206, rs2082806561, rs765302014	RCV003974815 RCV003894719 RCV003941598 RCV003932269 RCV003954406 RCV003963847

Show/Hide Text Mining Associations (93)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Aneuploidy	Associate	22370935
Arthritis Rheumatoid	Associate	36835215
Asthma	Associate	30150425
Astrocytoma	Associate	22370935
Ataxia Telangiectasia	Associate	34628594
Breast Neoplasms	Associate	18551366, 18701435, 21283680, 21701125, 21749698, 22864780, 24139550, 24642895, 25556451, 26446325, 26881229, 27571987, 28315507, 28864920, 28983784 View all (6 more)
Breast Neoplasms	Stimulate	23977219, 35691022
Breast Neoplasms	Inhibit	28983784
Breast Neoplasms Male	Associate	32295201
Calcinosis Cutis	Associate	29394274
Carcinogenesis	Associate	21283680, 26918347, 29895130
Carcinoma Hepatocellular	Associate	22691054, 24307625, 25337275, 29085212, 29895130, 32258128
Carcinoma Non Small Cell Lung	Associate	16407418, 21647442, 22052224, 23167352, 23924833, 24737519, 24933103, 26159902
Carcinoma Renal Cell	Associate	26682510
Carcinoma Squamous Cell	Associate	23443124
Chemical and Drug Induced Liver Injury	Associate	17197435
Chromosomal Instability	Associate	21035470
Chromosome Aberrations	Associate	21035470, 22370935
Colitis Ulcerative	Associate	25247297
Colorectal Neoplasms	Associate	12865926, 15679883, 19031937, 21104022, 22524842, 23894404, 24166604, 25520078, 26023803, 28453695, 29394274, 31350979
Colorectal Neoplasms	Stimulate	19031937
Conjunctivitis	Associate	21035470
Death	Associate	16407418, 22938418, 26505394, 27460091
Disease	Associate	30712190
Drug Related Side Effects and Adverse Reactions	Associate	22868256, 22982660, 27566557, 37774056
Early Onset Glaucoma	Associate	27460091
Endometriosis	Inhibit	20391347
Endometriosis	Associate	20391347, 24615029
Erythema	Associate	21749698
Esophageal Squamous Cell Carcinoma	Associate	26383967
Eye Diseases	Associate	21035470
Fanconi Anemia	Associate	31584931
Gastritis	Associate	16425350
Gastrointestinal Stromal Tumors	Associate	27460091, 29206199
Glioblastoma	Associate	22370935
Glioma	Associate	23244079, 23534771, 26400288
Gynecomastia	Associate	32295201
Head and Neck Neoplasms	Associate	25556492, 37774056
Helicobacter Infections	Associate	16425350
Hematologic Diseases	Associate	22868256
Hereditary Breast and Ovarian Cancer Syndrome	Associate	24139550, 29255180
Hodgkin Disease	Stimulate	19280628, 21374732
Hodgkin Disease	Associate	19280628
Inflammation	Associate	27683114
Leukemia Lymphocytic Chronic B Cell	Associate	22739018
Leukemia Myeloid Acute	Associate	12393447, 21951951
Lung Neoplasms	Associate	14534887, 17705814, 18990748, 23409158, 23443124, 26159902, 26918347
Lymphatic Metastasis	Associate	22864780, 24728564
Lymphoma	Associate	22524835
Lymphoma Follicular	Associate	25178586
Lymphoma Non Hodgkin	Associate	27566557
Melanoma	Associate	15009726
Meningioma	Associate	23534771
Mesothelioma Malignant	Associate	22982660
Mouth Diseases	Associate	18579371
Mouth Neoplasms	Associate	22726897, 37006067
Mouth Neoplasms	Stimulate	36149156
Myocardial Infarction	Associate	18712175
Neoplasm Metastasis	Associate	29394274
Neoplasms	Associate	12853621, 15679883, 17177211, 21035470, 21104022, 22370935, 23977219, 24728564, 25428673, 25556492, 26446325, 26682510, 29895130, 31584931, 32233832 View all (6 more)
Neoplasms	Stimulate	26446325
Neoplasms	Inhibit	32669601
Neoplasms Second Primary	Associate	28033528
Nervous System Diseases	Associate	21035470
Neuroblastoma	Associate	28033528
Neurodegenerative Diseases	Associate	21035470
Nevus	Associate	15009726
Osteosarcoma	Associate	26617908, 30539867
Ovarian Neoplasms	Associate	22938418, 24615029, 29255180, 30712190, 37344587
Ovarian Neoplasms	Stimulate	30712190
Pancreatic Neoplasms	Associate	16540687, 17986315
Peripheral Nervous System Diseases	Associate	21035470
Polyposis Syndrome Hereditary Mixed 1	Associate	16542436
Pre Eclampsia	Associate	24619222
Precancerous Conditions	Associate	21035470, 37006067
Prostatic Neoplasms	Associate	26339569, 36494413, 36969741
Pulmonary Disease Chronic Obstructive	Associate	24053728
Radiation Pneumonitis	Associate	22541966
Recombinant chromosome 8 syndrome	Associate	34628594, 37029129
Rectal Neoplasms	Associate	26023803
Skin Diseases	Associate	21035470
Smoke Inhalation Injury	Associate	14534887
Squamous Cell Carcinoma of Head and Neck	Associate	26505394, 27683114, 35390246
Stomach Neoplasms	Associate	16425350, 25428673, 25542228, 28415781
T Lymphocytopenia Idiopathic CD4 Positive	Associate	37344587
Thyroid Cancer Papillary	Associate	26264616, 28490032
Thyroid Neoplasms	Stimulate	24377596
Thyroid Neoplasms	Associate	24377596, 26045834, 26938431, 28490032
Triple Negative Breast Neoplasms	Associate	24728564
Urinary Bladder Neoplasms	Associate	17898541, 18630471, 19414392, 19429237, 27153553, 29267235
Urinary Bladder Neoplasms	Inhibit	27153553
Urogenital Diseases	Associate	36494413
Uterine Cervical Neoplasms	Associate	21790234, 23539294, 24377592, 28708208, 35996502

XRCC3 (X-ray repair cross complementing 3)