XIST (X inactive specific transcript)

Gene Gene information from NCBI Gene database.
Gene miRNA Other IDs Associated diseases
Entrez ID 7503
Gene name X inactive specific transcript
Gene symbol XIST
Synonyms (NCBI Gene)
DXS1089DXS399ELINC00001NCRNA00001SXI1swd66
Chromosome X
Chromosome location Xq13.2
Summary X inactivation is an early developmental process in mammalian females that transcriptionally silences one of the pair of X chromosomes, thus providing dosage equivalence between males and females. The process is regulated by several factors, including a r
miRNA miRNA information provided by mirtarbase database.
8
Gene miRNA Other IDs Associated diseases
Show/Hide all (8)
miRTarBase ID miRNA Experiments Reference
MIRT003171 hsa-miR-210-3p immunoprecipitaionLuciferase reporter assayMicroarrayqRT-PCR 19826008
MIRT003171 hsa-miR-210-3p immunoprecipitaionLuciferase reporter assayMicroarrayqRT-PCR 19826008
MIRT731182 hsa-miR-152-3p qRT-PCR/Luciferase reporter assayWestern blot 25578780
MIRT731182 hsa-miR-152-3p qRT-PCR/Luciferase reporter assayWestern blot 25578780
MIRT734229 hsa-miR-106a-5p Flow cytometryLuciferase reporter assayqRT-PCR 33400246
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Other IDs Associated diseases
MIM HGNC e!Ensembl
314670 12810 ENSG00000229807
Interactions View interactions
Associated diseases Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
33
Gene miRNA Other IDs Associated diseases
Show/Hide Causal Diseases (1)
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
X inactivation, familial skewed, 1 Likely pathogenic rs773396320 RCV000010433
Show/Hide Unknown Diseases (1)
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Phenotype Name Clinical Significance dbSNP ID RCV Accession
XIST-related disorder Likely benign; Benign rs765820028, rs193140316, rs6528, rs142303653, rs763261086, rs749949850, rs756172114, rs11553101, rs201357240, rs41307246, rs138241042, rs765472519, rs113875722, rs73486505, rs145461488
View all (17 more)		 RCV003919719
RCV003919746
RCV003907333
RCV003917313
RCV003929852
RCV003894307
RCV003906806
RCV003904056
RCV003916941
RCV003973848
RCV003909628
RCV003917179
RCV003931443
RCV003931614
RCV003941573
RCV003914366
RCV003914583
RCV003949356
RCV003951530
RCV003954705
RCV003922060
RCV003922094
RCV003922119
RCV003922233
RCV003926836
RCV003926846
RCV003926904
RCV003932021
RCV003934229
RCV003949235
RCV003956674
RCV003976528
Show/Hide Text Mining Associations (126)
Associations from Text MiningDisease associations identified through Pubtator
Disease Name Relationship Type References
Abortion Spontaneous Associate 37914735
Acute Kidney Injury Associate 31914881
Adenocarcinoma of Lung Associate 28961027, 31419261, 33771173
Alzheimer Disease Associate 36928034
Antiphospholipid Syndrome Stimulate 37914735
Aortic Dissection Associate 26339353
Arthritis Rheumatoid Associate 34165008, 37814309
Asthma Associate 33998076
Astrocytoma Associate 32647207
Atherosclerosis Associate 31539155, 32345778