Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	7447
Gene name	Visinin like 1
Gene symbol	VSNL1
Synonyms (NCBI Gene)	HLP3HPCAL3HUVISL1VILIPVILIP-1
Chromosome	2
Chromosome location	2p24.2
Summary	This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intra

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miRTarBase ID	miRNA	Experiments	Reference
MIRT003036	hsa-miR-181b-5p	Luciferase assay/RT-PCR	18184693
MIRT003036	hsa-miR-181b-5p	Luciferase reporter assay	18184693
MIRT003036	hsa-miR-181b-5p	Reporter assay;Other	18184693
MIRT721306	hsa-miR-518e-3p	HITS-CLIP	19536157
MIRT721305	hsa-miR-6873-5p	HITS-CLIP	19536157
MIRT721304	hsa-miR-520g-5p	HITS-CLIP	19536157
MIRT721303	hsa-miR-5087	HITS-CLIP	19536157
MIRT721302	hsa-miR-8068	HITS-CLIP	19536157
MIRT721301	hsa-miR-587	HITS-CLIP	19536157
MIRT552906	hsa-miR-22-3p	HITS-CLIP	23824327
MIRT552905	hsa-miR-1257	HITS-CLIP	23824327
MIRT552904	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT449351	hsa-miR-5585-3p	HITS-CLIP	23824327
MIRT552902	hsa-miR-6818-5p	HITS-CLIP	23824327
MIRT552903	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT607625	hsa-miR-3942-5p	HITS-CLIP	24906430
MIRT607624	hsa-miR-4703-5p	HITS-CLIP	24906430
MIRT607623	hsa-miR-16-2-3p	HITS-CLIP	24906430
MIRT607622	hsa-miR-195-3p	HITS-CLIP	24906430
MIRT552904	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT552902	hsa-miR-6818-5p	HITS-CLIP	24906430
MIRT607621	hsa-miR-147a	HITS-CLIP	24906430
MIRT607620	hsa-miR-5010-3p	HITS-CLIP	24906430
MIRT552903	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT552906	hsa-miR-22-3p	PAR-CLIP	20371350
MIRT552905	hsa-miR-1257	PAR-CLIP	20371350
MIRT552904	hsa-miR-6867-5p	PAR-CLIP	20371350
MIRT449351	hsa-miR-5585-3p	PAR-CLIP	20371350
MIRT552902	hsa-miR-6818-5p	PAR-CLIP	20371350
MIRT552903	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT552906	hsa-miR-22-3p	PAR-CLIP	21572407
MIRT552905	hsa-miR-1257	PAR-CLIP	21572407
MIRT552904	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT449351	hsa-miR-5585-3p	PAR-CLIP	21572407
MIRT552902	hsa-miR-6818-5p	PAR-CLIP	21572407
MIRT552903	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT449356	hsa-miR-548n	PAR-CLIP	22100165
MIRT449354	hsa-miR-548av-5p	PAR-CLIP	22100165
MIRT449353	hsa-miR-548k	PAR-CLIP	22100165
MIRT449352	hsa-miR-8054	PAR-CLIP	22100165
MIRT449351	hsa-miR-5585-3p	PAR-CLIP	22100165
MIRT449350	hsa-miR-3161	PAR-CLIP	22100165
MIRT449349	hsa-miR-599	PAR-CLIP	22100165
MIRT552905	hsa-miR-1257	HITS-CLIP	27418678
MIRT552905	hsa-miR-1257	HITS-CLIP	27418678
MIRT607621	hsa-miR-147a	HITS-CLIP	27418678
MIRT552906	hsa-miR-22-3p	HITS-CLIP	27418678
MIRT552906	hsa-miR-22-3p	HITS-CLIP	27418678
MIRT607620	hsa-miR-5010-3p	HITS-CLIP	27418678
MIRT449351	hsa-miR-5585-3p	HITS-CLIP	27418678
MIRT449351	hsa-miR-5585-3p	HITS-CLIP	27418678
MIRT552903	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT552902	hsa-miR-6818-5p	HITS-CLIP	27418678
MIRT552904	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT721306	hsa-miR-518e-3p	HITS-CLIP	19536157
MIRT721305	hsa-miR-6873-5p	HITS-CLIP	19536157
MIRT721304	hsa-miR-520g-5p	HITS-CLIP	19536157
MIRT721303	hsa-miR-5087	HITS-CLIP	19536157
MIRT721302	hsa-miR-8068	HITS-CLIP	19536157
MIRT721301	hsa-miR-587	HITS-CLIP	19536157
MIRT552906	hsa-miR-22-3p	HITS-CLIP	23824327
MIRT552905	hsa-miR-1257	HITS-CLIP	23824327
MIRT552904	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT449351	hsa-miR-5585-3p	HITS-CLIP	23824327
MIRT552902	hsa-miR-6818-5p	HITS-CLIP	23824327
MIRT552903	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT552906	hsa-miR-22-3p	PAR-CLIP	20371350
MIRT552905	hsa-miR-1257	PAR-CLIP	20371350
MIRT552904	hsa-miR-6867-5p	PAR-CLIP	20371350
MIRT449351	hsa-miR-5585-3p	PAR-CLIP	20371350
MIRT552902	hsa-miR-6818-5p	PAR-CLIP	20371350
MIRT552903	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT552906	hsa-miR-22-3p	PAR-CLIP	21572407
MIRT552905	hsa-miR-1257	PAR-CLIP	21572407
MIRT552904	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT449351	hsa-miR-5585-3p	PAR-CLIP	21572407
MIRT552902	hsa-miR-6818-5p	PAR-CLIP	21572407
MIRT552903	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT449356	hsa-miR-548n	PAR-CLIP	22100165
MIRT449354	hsa-miR-548av-5p	PAR-CLIP	22100165
MIRT449353	hsa-miR-548k	PAR-CLIP	22100165
MIRT449352	hsa-miR-8054	PAR-CLIP	22100165
MIRT449351	hsa-miR-5585-3p	PAR-CLIP	22100165
MIRT449350	hsa-miR-3161	PAR-CLIP	22100165
MIRT449349	hsa-miR-599	PAR-CLIP	22100165
MIRT1487861	hsa-miR-3064-3p	CLIP-seq
MIRT1487862	hsa-miR-4715-3p	CLIP-seq
MIRT1487863	hsa-miR-671-5p	CLIP-seq
MIRT2146805	hsa-miR-147	CLIP-seq
MIRT2146806	hsa-miR-3659	CLIP-seq
MIRT2146807	hsa-miR-4731-3p	CLIP-seq
MIRT2146808	hsa-miR-4801	CLIP-seq
MIRT2146809	hsa-miR-607	CLIP-seq
MIRT2146805	hsa-miR-147	CLIP-seq
MIRT2463337	hsa-miR-217	CLIP-seq
MIRT2463338	hsa-miR-4418	CLIP-seq
MIRT2463339	hsa-miR-509-3-5p	CLIP-seq
MIRT2463340	hsa-miR-509-5p	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IBA
GO:0005509	Function	Calcium ion binding	IEA
GO:0005515	Function	Protein binding	IPI	16189514, 16713569, 25416956, 32296183, 32814053
GO:0005829	Component	Cytosol	IEA
GO:0009966	Process	Regulation of signal transduction	IBA
GO:0016020	Component	Membrane	IEA
GO:0035774	Process	Positive regulation of insulin secretion involved in cellular response to glucose stimulus	IEA
GO:0045921	Process	Positive regulation of exocytosis	IEA
GO:0046676	Process	Negative regulation of insulin secretion	IEA
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
600817	12722	ENSG00000163032

P62760

Protein name

Visinin-like protein 1 (VILIP) (VLP-1) (Hippocalcin-like protein 3) (HLP3)

Protein function

Regulates (in vitro) the inhibition of rhodopsin phosphorylation in a calcium-dependent manner.

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00036	EF-hand_1	64 → 92	EF hand	Domain
PF13499	EF-hand_7	98 → 176	EF-hand domain pair	Domain
PF00036	EF-hand_1	100 → 128	EF hand	Domain

Tissue specificity

TISSUE SPECIFICITY: Brain and retina. Neuron-specific in the central and peripheral nervous system. Increased in the cerebrospinal fluid of Alzheimer disease patients (at protein level). {ECO:0000269|PubMed:18703769}.

Sequence

MGKQNSKLAPEVMEDLVKSTEFNEHELKQWYKGFLKDCPSGRLNLEEFQQLYVKFFPYGD
ASKFAQHAFRTFDKNGDGTIDFREFICALSITSRGSFEQKLNWAFNMYDLDGDGKITRVE
MLEIIEAIYKMVGTVIMMKMNEDGLTPEQRVDKIFSKMDKNKDDQITLDEFKEAAKSDPS
IVLLLQCDIQK

Sequence length

191

Interactions

View interactions

VSNL1 (visinin like 1)