Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	7442
Gene name	Transient receptor potential cation channel subfamily V member 1
Gene symbol	TRPV1
Synonyms (NCBI Gene)	VR1
Chromosome	17
Chromosome location	17p13.2
Summary	Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a r

185

Show/Hide all (185)

miRTarBase ID	miRNA	Experiments	Reference
MIRT024445	hsa-miR-215-5p	Microarray	19074876
MIRT026638	hsa-miR-192-5p	Microarray	19074876
MIRT051594	hsa-let-7e-5p	CLASH	23622248
MIRT1457805	hsa-miR-1178	CLIP-seq
MIRT1457806	hsa-miR-1227	CLIP-seq
MIRT1457807	hsa-miR-1228	CLIP-seq
MIRT1457808	hsa-miR-1253	CLIP-seq
MIRT1457809	hsa-miR-1262	CLIP-seq
MIRT1457810	hsa-miR-1273g	CLIP-seq
MIRT1457811	hsa-miR-1909	CLIP-seq
MIRT1457812	hsa-miR-217	CLIP-seq
MIRT1457813	hsa-miR-2467-5p	CLIP-seq
MIRT1457814	hsa-miR-3122	CLIP-seq
MIRT1457815	hsa-miR-335	CLIP-seq
MIRT1457816	hsa-miR-342-3p	CLIP-seq
MIRT1457817	hsa-miR-3622a-3p	CLIP-seq
MIRT1457818	hsa-miR-3622b-3p	CLIP-seq
MIRT1457819	hsa-miR-3689a-3p	CLIP-seq
MIRT1457820	hsa-miR-3689c	CLIP-seq
MIRT1457821	hsa-miR-3911	CLIP-seq
MIRT1457822	hsa-miR-3913-5p	CLIP-seq
MIRT1457823	hsa-miR-3926	CLIP-seq
MIRT1457824	hsa-miR-3934	CLIP-seq
MIRT1457825	hsa-miR-4252	CLIP-seq
MIRT1457826	hsa-miR-4270	CLIP-seq
MIRT1457827	hsa-miR-4284	CLIP-seq
MIRT1457828	hsa-miR-4433	CLIP-seq
MIRT1457829	hsa-miR-4441	CLIP-seq
MIRT1457830	hsa-miR-4443	CLIP-seq
MIRT1457831	hsa-miR-4459	CLIP-seq
MIRT1457832	hsa-miR-4473	CLIP-seq
MIRT1457833	hsa-miR-450b-3p	CLIP-seq
MIRT1457834	hsa-miR-4695-5p	CLIP-seq
MIRT1457835	hsa-miR-4701-3p	CLIP-seq
MIRT1457836	hsa-miR-4728-5p	CLIP-seq
MIRT1457837	hsa-miR-4747-5p	CLIP-seq
MIRT1457838	hsa-miR-4764-5p	CLIP-seq
MIRT1457839	hsa-miR-4768-3p	CLIP-seq
MIRT1457840	hsa-miR-4786-5p	CLIP-seq
MIRT1457841	hsa-miR-512-3p	CLIP-seq
MIRT1457842	hsa-miR-520f	CLIP-seq
MIRT1457843	hsa-miR-541	CLIP-seq
MIRT1457844	hsa-miR-544b	CLIP-seq
MIRT1457845	hsa-miR-548c-3p	CLIP-seq
MIRT1457846	hsa-miR-548s	CLIP-seq
MIRT1457847	hsa-miR-550a	CLIP-seq
MIRT1457848	hsa-miR-654-5p	CLIP-seq
MIRT1457849	hsa-miR-658	CLIP-seq
MIRT1457850	hsa-miR-665	CLIP-seq
MIRT1457851	hsa-miR-671-5p	CLIP-seq
MIRT1457852	hsa-miR-769-3p	CLIP-seq
MIRT1457853	hsa-miR-890	CLIP-seq
MIRT1457854	hsa-miR-1343	CLIP-seq
MIRT1457855	hsa-miR-3074-5p	CLIP-seq
MIRT1457856	hsa-miR-378g	CLIP-seq
MIRT1457857	hsa-miR-4699-3p	CLIP-seq
MIRT1457858	hsa-miR-4729	CLIP-seq
MIRT1457859	hsa-miR-579	CLIP-seq
MIRT1457817	hsa-miR-3622a-3p	CLIP-seq
MIRT1457818	hsa-miR-3622b-3p	CLIP-seq
MIRT1457823	hsa-miR-3926	CLIP-seq
MIRT1457828	hsa-miR-4433	CLIP-seq
MIRT1457831	hsa-miR-4459	CLIP-seq
MIRT1457837	hsa-miR-4747-5p	CLIP-seq
MIRT1457839	hsa-miR-4768-3p	CLIP-seq
MIRT1457840	hsa-miR-4786-5p	CLIP-seq
MIRT1457843	hsa-miR-541	CLIP-seq
MIRT1457844	hsa-miR-544b	CLIP-seq
MIRT1457846	hsa-miR-548s	CLIP-seq
MIRT1457847	hsa-miR-550a	CLIP-seq
MIRT1457848	hsa-miR-654-5p	CLIP-seq
MIRT1457851	hsa-miR-671-5p	CLIP-seq
MIRT1457853	hsa-miR-890	CLIP-seq
MIRT1457807	hsa-miR-1228	CLIP-seq
MIRT2137348	hsa-miR-1285	CLIP-seq
MIRT1457814	hsa-miR-3122	CLIP-seq
MIRT1457815	hsa-miR-335	CLIP-seq
MIRT1457817	hsa-miR-3622a-3p	CLIP-seq
MIRT1457818	hsa-miR-3622b-3p	CLIP-seq
MIRT1457819	hsa-miR-3689a-3p	CLIP-seq
MIRT1457820	hsa-miR-3689c	CLIP-seq
MIRT1457822	hsa-miR-3913-5p	CLIP-seq
MIRT1457823	hsa-miR-3926	CLIP-seq
MIRT1457828	hsa-miR-4433	CLIP-seq
MIRT1457831	hsa-miR-4459	CLIP-seq
MIRT1457836	hsa-miR-4728-5p	CLIP-seq
MIRT2137349	hsa-miR-4738-3p	CLIP-seq
MIRT1457837	hsa-miR-4747-5p	CLIP-seq
MIRT1457839	hsa-miR-4768-3p	CLIP-seq
MIRT1457840	hsa-miR-4786-5p	CLIP-seq
MIRT1457843	hsa-miR-541	CLIP-seq
MIRT1457844	hsa-miR-544b	CLIP-seq
MIRT1457846	hsa-miR-548s	CLIP-seq
MIRT1457847	hsa-miR-550a	CLIP-seq
MIRT2137350	hsa-miR-564	CLIP-seq
MIRT1457848	hsa-miR-654-5p	CLIP-seq
MIRT1457851	hsa-miR-671-5p	CLIP-seq
MIRT2137351	hsa-miR-766	CLIP-seq
MIRT1457853	hsa-miR-890	CLIP-seq
MIRT1457807	hsa-miR-1228	CLIP-seq
MIRT1457814	hsa-miR-3122	CLIP-seq
MIRT1457815	hsa-miR-335	CLIP-seq
MIRT1457816	hsa-miR-342-3p	CLIP-seq
MIRT1457817	hsa-miR-3622a-3p	CLIP-seq
MIRT1457818	hsa-miR-3622b-3p	CLIP-seq
MIRT1457819	hsa-miR-3689a-3p	CLIP-seq
MIRT1457820	hsa-miR-3689c	CLIP-seq
MIRT1457822	hsa-miR-3913-5p	CLIP-seq
MIRT1457823	hsa-miR-3926	CLIP-seq
MIRT1457827	hsa-miR-4284	CLIP-seq
MIRT1457828	hsa-miR-4433	CLIP-seq
MIRT1457831	hsa-miR-4459	CLIP-seq
MIRT1457836	hsa-miR-4728-5p	CLIP-seq
MIRT1457839	hsa-miR-4768-3p	CLIP-seq
MIRT1457840	hsa-miR-4786-5p	CLIP-seq
MIRT1457843	hsa-miR-541	CLIP-seq
MIRT1457844	hsa-miR-544b	CLIP-seq
MIRT1457846	hsa-miR-548s	CLIP-seq
MIRT1457848	hsa-miR-654-5p	CLIP-seq
MIRT1457853	hsa-miR-890	CLIP-seq
MIRT1457807	hsa-miR-1228	CLIP-seq
MIRT1457814	hsa-miR-3122	CLIP-seq
MIRT1457816	hsa-miR-342-3p	CLIP-seq
MIRT1457817	hsa-miR-3622a-3p	CLIP-seq
MIRT1457818	hsa-miR-3622b-3p	CLIP-seq
MIRT1457819	hsa-miR-3689a-3p	CLIP-seq
MIRT1457820	hsa-miR-3689c	CLIP-seq
MIRT1457822	hsa-miR-3913-5p	CLIP-seq
MIRT1457836	hsa-miR-4728-5p	CLIP-seq
MIRT1457844	hsa-miR-544b	CLIP-seq
MIRT1457807	hsa-miR-1228	CLIP-seq
MIRT2462459	hsa-miR-186	CLIP-seq
MIRT2462460	hsa-miR-3120-5p	CLIP-seq
MIRT1457814	hsa-miR-3122	CLIP-seq
MIRT2462461	hsa-miR-3613-3p	CLIP-seq
MIRT1457817	hsa-miR-3622a-3p	CLIP-seq
MIRT1457818	hsa-miR-3622b-3p	CLIP-seq
MIRT1457819	hsa-miR-3689a-3p	CLIP-seq
MIRT1457820	hsa-miR-3689c	CLIP-seq
MIRT2462462	hsa-miR-371-5p	CLIP-seq
MIRT2462463	hsa-miR-371b-5p	CLIP-seq
MIRT1457822	hsa-miR-3913-5p	CLIP-seq
MIRT1457828	hsa-miR-4433	CLIP-seq
MIRT1457831	hsa-miR-4459	CLIP-seq
MIRT1457836	hsa-miR-4728-5p	CLIP-seq
MIRT1457839	hsa-miR-4768-3p	CLIP-seq
MIRT2462464	hsa-miR-4778-5p	CLIP-seq
MIRT1457840	hsa-miR-4786-5p	CLIP-seq
MIRT1457843	hsa-miR-541	CLIP-seq
MIRT1457844	hsa-miR-544b	CLIP-seq
MIRT1457845	hsa-miR-548c-3p	CLIP-seq
MIRT1457848	hsa-miR-654-5p	CLIP-seq
MIRT2137349	hsa-miR-4738-3p	CLIP-seq
MIRT1457807	hsa-miR-1228	CLIP-seq
MIRT2462459	hsa-miR-186	CLIP-seq
MIRT2462460	hsa-miR-3120-5p	CLIP-seq
MIRT1457814	hsa-miR-3122	CLIP-seq
MIRT2651543	hsa-miR-3163	CLIP-seq
MIRT1457815	hsa-miR-335	CLIP-seq
MIRT2462461	hsa-miR-3613-3p	CLIP-seq
MIRT1457817	hsa-miR-3622a-3p	CLIP-seq
MIRT1457818	hsa-miR-3622b-3p	CLIP-seq
MIRT1457819	hsa-miR-3689a-3p	CLIP-seq
MIRT1457820	hsa-miR-3689c	CLIP-seq
MIRT2462462	hsa-miR-371-5p	CLIP-seq
MIRT2462463	hsa-miR-371b-5p	CLIP-seq
MIRT1457822	hsa-miR-3913-5p	CLIP-seq
MIRT1457823	hsa-miR-3926	CLIP-seq
MIRT1457828	hsa-miR-4433	CLIP-seq
MIRT1457831	hsa-miR-4459	CLIP-seq
MIRT1457836	hsa-miR-4728-5p	CLIP-seq
MIRT1457837	hsa-miR-4747-5p	CLIP-seq
MIRT1457839	hsa-miR-4768-3p	CLIP-seq
MIRT2462464	hsa-miR-4778-5p	CLIP-seq
MIRT1457840	hsa-miR-4786-5p	CLIP-seq
MIRT1457843	hsa-miR-541	CLIP-seq
MIRT1457844	hsa-miR-544b	CLIP-seq
MIRT1457845	hsa-miR-548c-3p	CLIP-seq
MIRT1457846	hsa-miR-548s	CLIP-seq
MIRT1457847	hsa-miR-550a	CLIP-seq
MIRT2137350	hsa-miR-564	CLIP-seq
MIRT1457848	hsa-miR-654-5p	CLIP-seq
MIRT1457851	hsa-miR-671-5p	CLIP-seq
MIRT1457853	hsa-miR-890	CLIP-seq
MIRT2137349	hsa-miR-4738-3p	CLIP-seq

Show/Hide all (74)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0000166	Function	Nucleotide binding	IEA
GO:0001659	Process	Temperature homeostasis	IEA
GO:0001660	Process	Fever generation	IEA
GO:0002024	Process	Diet induced thermogenesis	IEA
GO:0002790	Process	Peptide secretion	IEA
GO:0004888	Function	Transmembrane signaling receptor activity	ISS
GO:0005216	Function	Monoatomic ion channel activity	IEA
GO:0005230	Function	Extracellular ligand-gated monoatomic ion channel activity	IDA	11226139
GO:0005231	Function	Excitatory extracellular ligand-gated monoatomic ion channel activity	ISS
GO:0005245	Function	Voltage-gated calcium channel activity	TAS
GO:0005262	Function	Calcium channel activity	IBA
GO:0005262	Function	Calcium channel activity	IEA
GO:0005262	Function	Calcium channel activity	TAS	9349813
GO:0005515	Function	Protein binding	IPI	29656858
GO:0005516	Function	Calmodulin binding	IEA
GO:0005516	Function	Calmodulin binding	ISS
GO:0005524	Function	ATP binding	IEA
GO:0005524	Function	ATP binding	ISS
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	ISS
GO:0005886	Component	Plasma membrane	TAS	9349813
GO:0006629	Process	Lipid metabolic process	IEA
GO:0006811	Process	Monoatomic ion transport	IEA
GO:0006816	Process	Calcium ion transport	IEA
GO:0006816	Process	Calcium ion transport	IEA
GO:0007166	Process	Cell surface receptor signaling pathway	TAS	9349813
GO:0007635	Process	Chemosensory behavior	TAS	9349813
GO:0009268	Process	Response to pH	IEA
GO:0009408	Process	Response to heat	IEA
GO:0014832	Process	Urinary bladder smooth muscle contraction	IEA
GO:0015278	Function	Intracellularly gated calcium channel activity	ISS
GO:0016020	Component	Membrane	IDA	10201375
GO:0016020	Component	Membrane	IEA
GO:0019233	Process	Sensory perception of pain	IEA
GO:0019722	Process	Calcium-mediated signaling	IEA
GO:0032591	Component	Dendritic spine membrane	IEA
GO:0034220	Process	Monoatomic ion transmembrane transport	IEA
GO:0034605	Process	Cellular response to heat	IDA	11226139
GO:0035091	Function	Phosphatidylinositol binding	ISS
GO:0042995	Component	Cell projection	IEA
GO:0043005	Component	Neuron projection	IEA
GO:0045202	Component	Synapse	IEA
GO:0045211	Component	Postsynaptic membrane	IEA
GO:0045211	Component	Postsynaptic membrane	IEA
GO:0045211	Component	Postsynaptic membrane	ISS
GO:0046872	Function	Metal ion binding	IEA
GO:0048265	Process	Response to pain	IEA
GO:0048266	Process	Behavioral response to pain	IEA
GO:0050909	Process	Sensory perception of taste	IEA
GO:0050954	Process	Sensory perception of mechanical stimulus	IEA
GO:0050955	Process	Thermoception	IDA	10201375
GO:0050960	Process	Detection of temperature stimulus involved in thermoception	IEA
GO:0050965	Process	Detection of temperature stimulus involved in sensory perception of pain	IEA
GO:0050968	Process	Detection of chemical stimulus involved in sensory perception of pain	IEA
GO:0051219	Function	Phosphoprotein binding	IPI	19801576
GO:0051289	Process	Protein homotetramerization	ISS
GO:0055085	Process	Transmembrane transport	IEA
GO:0060079	Process	Excitatory postsynaptic potential	IEA
GO:0060083	Process	Smooth muscle contraction involved in micturition	IEA
GO:0070588	Process	Calcium ion transmembrane transport	IEA
GO:0070588	Process	Calcium ion transmembrane transport	ISS
GO:0070588	Process	Calcium ion transmembrane transport	TAS
GO:0071312	Process	Cellular response to alkaloid	ISS
GO:0071318	Process	Cellular response to ATP	ISS
GO:0071468	Process	Cellular response to acidic pH	IDA	11226139
GO:0097603	Function	Temperature-gated ion channel activity	IEA
GO:0098703	Process	Calcium ion import across plasma membrane	IBA
GO:0098703	Process	Calcium ion import across plasma membrane	IDA	11226139
GO:0098982	Component	GABA-ergic synapse	IEA
GO:1901594	Process	Response to capsazepine	IMP	11226139
GO:1901594	Process	Response to capsazepine	ISS
GO:1902656	Process	Calcium ion import into cytosol	IEA

MIM	HGNC	e!Ensembl
602076	12716	ENSG00000196689

Q8NER1

Protein name

Transient receptor potential cation channel subfamily V member 1 (TrpV1) (Capsaicin receptor) (Osm-9-like TRP channel 1) (OTRPC1) (Vanilloid receptor 1)

Protein function

Non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli (PubMed:11050376, PubMed:11243859, PubMed:11226139, PubMed:12077606). Seems to mediate proton influx and may be involved in intracellular

PDB

6L93 , 8GF8 , 8GF9 , 8GFA , 8JQR , 8X94 , 8YCP

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12796	Ank_2	118 → 232	Ankyrin repeats (3 copies)	Repeat
PF00520	Ion_trans	432 → 695	Ion transport protein	Family

Tissue specificity

TISSUE SPECIFICITY: Widely expressed at low levels. Expression is elevated in dorsal root ganglia. In skin, expressed in cutaneous sensory nerve fibers, mast cells, epidermal keratinocytes, dermal blood vessels, the inner root sheet and the infundibulum o

Sequence

MKKWSSTDLGAAADPLQKDTCPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFP
VDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFE
AVAQNNCQDLESLLLFLQKSKKHLTDNEFKDPETGKTCLLKAMLNLHDGQNTTIPLLLEI
ARQTDSLKELVNASYTDSYYKGQTALHIAIERRNMALVTLLVENGADVQAAAHGDFFKKT
KGRPGFYFGELPLSLAACTNQLGIVKFLLQNSWQTADISARDSVGNTVLHALVEVADNTA
DNTKFVTSMYNEILMLGAKLHPTLKLEELTNKKGMTPLALAAGTGKIGVLAYILQREIQE
PECRHLSRKFTEWAYGPVHSSLYDLSCIDTCEKNSVLEVIAYSSSETPNRHDMLLVEPLN
RLLQDKWDRFVKRIFYFNFLVYCLYMIIFTMAAYYRPVDGLPPFKMEKTGDYFRVTGEIL
SVLGGVYFFFRGIQYFLQRRPSMKTLFVDSYSEMLFFLQSLFMLATVVLYFSHLKEYVAS
MVFSLALGWTNMLYYTRGFQQMGIYAVMIEKMILRDLCRFMFVYIVFLFGFSTAVVTLIE
DGKNDSLPSESTSHRWRGPACRPPDSSYNSLYSTCLELFKFTIGMGDLEFTENYDFKAVF
IILLLAYVILTYILLLNMLIALMGETVNKIAQESKNIWKLQRAITILDTEKSFLKCMRKA
FRSGKLLQVGYTPDGKDDYRWCFRVDEVNWTTWNTNVGIINEDPGNCEGVKRTLSFSLRS
SRVSGRHWKNFALVPLLREASARDRQSAQPEEVYLRQFSGSLKPEDAEVFKSPAASGEK

Sequence length

839

Interactions

View interactions

	KEGG		Reactome
	Neuroactive ligand-receptor interaction Inflammatory mediator regulation of TRP channels		TRP channels

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
See cases	Likely pathogenic	rs774145606	RCV002463813

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Malignant hyperthermia of anesthesia	Uncertain significance	rs771123129	RCV002225239

Show/Hide Text Mining Associations (120)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Abdominal Injuries	Associate	19056576
Abdominal Pain	Associate	18252749, 34472640
Acne Vulgaris	Associate	18769453
Airway Obstruction	Associate	33787326
Alzheimer Disease	Associate	36065437
Asthma	Associate	20639579, 22242698, 27758864, 33787326, 36847817
Atrial Fibrillation	Associate	28839241, 33062700
beta Thalassemia	Associate	25216685
Bone Diseases	Associate	31701920, 35472140, 35862357
Bone Diseases Metabolic	Associate	25216685
Bone Resorption	Associate	35472140
Bronchiolitis	Associate	33787326
Carcinoma Ovarian Epithelial	Associate	32345672
Carcinoma Papillary	Associate	24868547
Carcinoma Squamous Cell	Associate	28081185
Cardiomyopathies	Associate	35905222
Cardiovascular Diseases	Associate	36899055
Charcot Marie Tooth disease Type 1C	Stimulate	36614264
Cold Injury	Associate	21468319
Colitis Ulcerative	Associate	30150894
Colorectal Neoplasms	Associate	22922338, 34791641
Colorectal Neoplasms	Inhibit	31183372
Constipation	Associate	28478727
Conversion Disorder	Associate	19619644
Cough	Associate	19463161, 20639579, 22443337, 24296694, 29149168, 32938990, 33787326, 35509099
Cough	Stimulate	30883022
Cystinosis	Associate	27734949
Cystitis	Associate	33664402
Depressive Disorder	Stimulate	24143878
Depressive Disorder	Associate	37883944
Diabetes Mellitus	Associate	17913835, 24340836, 24798548
Diabetes Mellitus Type 1	Associate	24340836
Diabetic Neuropathies	Inhibit	17521436
Diabetic Neuropathies	Associate	36430572
Drug Hypersensitivity	Associate	18252749, 20639579, 29794793, 33655767
Drug Hypersensitivity	Stimulate	35689659
Drug Related Side Effects and Adverse Reactions	Associate	19619644
Dry Eye Syndromes	Associate	25170901
Dyspareunia	Associate	28478727
Endometrial Neoplasms	Inhibit	40243844
Endometriosis	Stimulate	25029427, 28478727, 37405438
Esophageal Squamous Cell Carcinoma	Associate	30761248
Fatigue	Associate	19647494
Flushing	Associate	25752528
Ganglion Cysts	Associate	31547874
Gastroesophageal Reflux	Associate	26337663
Gastroesophageal Reflux	Stimulate	33655767
Glioblastoma	Inhibit	17442041
Glioblastoma	Associate	26088448, 33624687
Glioma	Associate	17442041, 27829230
Glioma	Stimulate	39189437
Haspeslagh Fryns Muelenaere syndrome	Associate	36555331
Heart Failure	Associate	32105387, 37798313
Heartburn	Associate	33655767
Hematologic Neoplasms	Associate	35477804
Hereditary Sensory and Autonomic Neuropathies	Associate	27734949
Hot Flashes	Associate	32217888
Hyperalgesia	Associate	21468319, 30938826
Hyperalgesia	Stimulate	35689659
Hypertension Pulmonary	Associate	33103544
Idiopathic Pulmonary Fibrosis	Stimulate	29149168
Immune System Diseases	Associate	19619644
Infections	Stimulate	33787326
Inflammation	Associate	18769453, 19619644, 19695100, 30150894, 34282193
Inflammation	Stimulate	22242698, 22566504
Inflammation	Inhibit	37175520
Inflammatory Bowel Diseases	Associate	35472140
Intervertebral Disc Degeneration	Associate	30717434
Iron Overload	Associate	25216685
Irritable Bowel Syndrome	Associate	18252749, 22870787, 29794793, 34472640
Irritable Bowel Syndrome	Stimulate	22870787, 35502856
Kidney Failure Chronic	Stimulate	19619644
Lead Poisoning Nervous System	Associate	33381275
Leukemia Monocytic Acute	Stimulate	35477804
Lung Neoplasms	Associate	30883022
Lymphoma B Cell	Stimulate	35477804
Lymphoma B Cell Marginal Zone	Associate	28081185
Malformations of Cortical Development Group I	Stimulate	31547874
Mandibular Nerve Injuries	Associate	35354377
Melanoma	Inhibit	29580868
Melanoma	Associate	34199609
Migraine Disorders	Associate	31014225
Multiple Myeloma	Stimulate	35477804
Myalgia	Associate	19647494
Necrosis	Stimulate	34440820
Neoplasms	Inhibit	24868547, 31183372
Neoplasms	Associate	25703814, 28081185, 29580868, 31591020, 34199609, 35558077
Nervous System Diseases	Associate	36672910
Neuralgia	Associate	21468319, 35354377
Neurogenic Inflammation	Associate	17913835
Neurotoxicity Syndromes	Associate	23963862
Obesity	Associate	24798548
Osteolysis Essential	Associate	39940911
Osteoporosis	Associate	25216685, 31701920, 35862357
Osteoporosis	Inhibit	35472140
Ovarian Neoplasms	Stimulate	28478727
Overtraining Syndrome	Associate	25305179
Pain	Associate	16174661, 17927589, 18252749, 19695100, 22870787, 29596157, 30209980, 30717434, 35806193, 37216549, 37366593
Pancreatic Neoplasms	Stimulate	16174661
Pancreatitis Chronic	Stimulate	16174661
Peripheral Nervous System Diseases	Associate	35689659, 35806193, 36672910
Phenylketonurias	Associate	27979859
Polyneuropathies	Associate	37175520
Prostate cancer familial	Associate	35477804
Prostatic Neoplasms	Associate	25481381
Pruritus	Associate	30938826, 37453614
Pterygium	Associate	36555331
Pulmonary Disease Chronic Obstructive	Associate	22242698, 33103544
Respiratory Sounds	Associate	20639579
Rosacea	Associate	22189789
Sarcoma Ewing	Associate	39940911
Sebaceous Gland Diseases	Associate	18769453
Skin Neoplasms	Associate	34199609
Small Fiber Neuropathy	Associate	36430572
Squamous Cell Carcinoma of Head and Neck	Stimulate	28081185, 35163843
Status Asthmaticus	Associate	22443337, 33787326
Taste Disorders	Associate	30060620, 37883944
Thyroid Carcinoma Anaplastic	Associate	34751390
Urinary Bladder Overactive	Associate	22691178
Visceral Pain	Associate	18252749

TRPV1 (transient receptor potential cation channel subfamily V member 1)