VIPR1 (vasoactive intestinal peptide receptor 1)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 7433 |
| Gene name | Vasoactive intestinal peptide receptor 1 |
| Gene symbol | VIPR1 |
| Synonyms (NCBI Gene) |
HVR1IIPACAP-R-2PACAP-R2RDC1V1RGVAPC1VIP-R-1VIPRVIRGVPAC1VPAC1RVPCAP1R
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| Chromosome | 3 |
| Chromosome location | 3p22.1 |
| Summary | This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its act |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P32241 | |||||||||||||||
| Protein name | Vasoactive intestinal polypeptide receptor 1 (VIP-R-1) (Pituitary adenylate cyclase-activating polypeptide type II receptor) (PACAP type II receptor) (PACAP-R-2) (PACAP-R2) (VPAC1 receptor) (VPAC1R) | |||||||||||||||
| Protein function | G protein-coupled receptor activated by the neuropeptides vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating polypeptide (ADCYAP1/PACAP) (PubMed:35477937, PubMed:36385145, PubMed:8179610). Binds VIP and both PACAP27 a | |||||||||||||||
| PDB | 1OF2 , 1OGT , 3B3I , 3B6S , 3DTX , 3HCV , 5DEF , 5DEG , 5IB1 , 5IB2 , 5IB3 , 5IB4 , 5IB5 , 6VN7 , 7ALO , 8E3Y , 8E3Z | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in | |||||||||||||||
| Sequence |
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| Sequence length | 457 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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