Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID	7412
Gene name	Vascular cell adhesion molecule 1
Gene symbol	VCAM1
Synonyms (NCBI Gene)	CD106INCAM-100
Chromosome	1
Chromosome location	1p21.2
Summary	This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in

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miRTarBase ID	miRNA	Experiments	Reference
MIRT004007	hsa-miR-200a-3p	Microarray	17875710
MIRT004081	hsa-miR-126-3p	Luciferase reporter assayWestern blot	18227515
MIRT004081	hsa-miR-126-3p	Luciferase reporter assayWestern blot	18227515
MIRT020917	hsa-miR-155-5p	qRT-PCR	21310411
MIRT004081	hsa-miR-126-3p	Reporter assay;Other	18227515
MIRT715363	hsa-miR-181a-5p	HITS-CLIP	19536157
MIRT715362	hsa-miR-181c-5p	HITS-CLIP	19536157
MIRT715361	hsa-miR-181d-5p	HITS-CLIP	19536157
MIRT715360	hsa-miR-4262	HITS-CLIP	19536157
MIRT715359	hsa-miR-181b-5p	HITS-CLIP	19536157
MIRT715358	hsa-miR-506-5p	HITS-CLIP	19536157
MIRT715357	hsa-miR-211-3p	HITS-CLIP	19536157
MIRT715356	hsa-miR-4270	HITS-CLIP	19536157
MIRT715355	hsa-miR-4441	HITS-CLIP	19536157
MIRT715354	hsa-miR-6754-5p	HITS-CLIP	19536157
MIRT715353	hsa-miR-3691-3p	HITS-CLIP	19536157
MIRT715352	hsa-miR-3127-5p	HITS-CLIP	19536157
MIRT504357	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT504356	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT504355	hsa-miR-6074	HITS-CLIP	21572407
MIRT707385	hsa-miR-3183	HITS-CLIP	21572407
MIRT707384	hsa-miR-4723-3p	HITS-CLIP	21572407
MIRT707383	hsa-miR-6769b-3p	HITS-CLIP	21572407
MIRT707382	hsa-miR-136-5p	HITS-CLIP	21572407
MIRT707381	hsa-miR-6845-3p	HITS-CLIP	21572407
MIRT707380	hsa-miR-7110-3p	HITS-CLIP	21572407
MIRT504354	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT504353	hsa-miR-130a-5p	HITS-CLIP	21572407
MIRT504352	hsa-miR-23a-3p	HITS-CLIP	21572407
MIRT504351	hsa-miR-23b-3p	HITS-CLIP	21572407
MIRT504350	hsa-miR-23c	HITS-CLIP	21572407
MIRT504356	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT504355	hsa-miR-6074	HITS-CLIP	21572407
MIRT504354	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT504353	hsa-miR-130a-5p	HITS-CLIP	21572407
MIRT504352	hsa-miR-23a-3p	HITS-CLIP	21572407
MIRT504351	hsa-miR-23b-3p	HITS-CLIP	21572407
MIRT504350	hsa-miR-23c	HITS-CLIP	21572407
MIRT504357	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT504355	hsa-miR-6074	HITS-CLIP	23313552
MIRT504354	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT504353	hsa-miR-130a-5p	HITS-CLIP	23313552
MIRT504352	hsa-miR-23a-3p	HITS-CLIP	23313552
MIRT504351	hsa-miR-23b-3p	HITS-CLIP	23313552
MIRT504350	hsa-miR-23c	HITS-CLIP	23313552
MIRT504357	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT635479	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT635478	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT635477	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT635476	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT635475	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT635474	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT635473	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT619599	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT619598	hsa-miR-519d-5p	HITS-CLIP	23824327
MIRT619599	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT619598	hsa-miR-519d-5p	HITS-CLIP	23824327
MIRT504356	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT504355	hsa-miR-6074	HITS-CLIP	23824327
MIRT504354	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT504353	hsa-miR-130a-5p	HITS-CLIP	23824327
MIRT504352	hsa-miR-23a-3p	HITS-CLIP	23824327
MIRT504351	hsa-miR-23b-3p	HITS-CLIP	23824327
MIRT504350	hsa-miR-23c	HITS-CLIP	23824327
MIRT504357	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT619599	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT619598	hsa-miR-519d-5p	HITS-CLIP	23824327
MIRT504356	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT504355	hsa-miR-6074	HITS-CLIP	23824327
MIRT610905	hsa-miR-5092	HITS-CLIP	23824327
MIRT504354	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT504353	hsa-miR-130a-5p	HITS-CLIP	23824327
MIRT504352	hsa-miR-23a-3p	HITS-CLIP	23824327
MIRT504351	hsa-miR-23b-3p	HITS-CLIP	23824327
MIRT504350	hsa-miR-23c	HITS-CLIP	23824327
MIRT504357	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT504355	hsa-miR-6074	PAR-CLIP	21572407
MIRT504354	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT504353	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT504352	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT504351	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT504350	hsa-miR-23c	PAR-CLIP	21572407
MIRT504357	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT504356	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT504355	hsa-miR-6074	PAR-CLIP	21572407
MIRT504354	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT504353	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT504352	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT504351	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT504350	hsa-miR-23c	PAR-CLIP	21572407
MIRT504357	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT504356	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT504355	hsa-miR-6074	PAR-CLIP	21572407
MIRT504354	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT504353	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT504352	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT504351	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT504350	hsa-miR-23c	PAR-CLIP	21572407
MIRT504357	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT533259	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT533258	hsa-miR-6856-3p	PAR-CLIP	22012620
MIRT533257	hsa-miR-5694	PAR-CLIP	22012620
MIRT504356	hsa-miR-5011-5p	PAR-CLIP	22012620
MIRT533256	hsa-miR-96-3p	PAR-CLIP	22012620
MIRT533255	hsa-miR-2467-3p	PAR-CLIP	22012620
MIRT533254	hsa-miR-2116-5p	PAR-CLIP	22012620
MIRT533253	hsa-miR-22-5p	PAR-CLIP	22012620
MIRT533252	hsa-miR-6844	PAR-CLIP	22012620
MIRT533251	hsa-miR-1273h-3p	PAR-CLIP	22012620
MIRT533250	hsa-miR-3678-3p	PAR-CLIP	22012620
MIRT533249	hsa-miR-4677-5p	PAR-CLIP	22012620
MIRT533248	hsa-miR-6516-5p	PAR-CLIP	22012620
MIRT504357	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT504355	hsa-miR-6074	PAR-CLIP	23446348
MIRT504354	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT504353	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT504352	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT504351	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT504350	hsa-miR-23c	PAR-CLIP	23446348
MIRT504357	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT504356	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT504355	hsa-miR-6074	PAR-CLIP	23446348
MIRT504354	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT504353	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT504352	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT504351	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT504350	hsa-miR-23c	PAR-CLIP	23446348
MIRT533255	hsa-miR-2467-3p	PAR-CLIP	27292025
MIRT533257	hsa-miR-5694	PAR-CLIP	27292025
MIRT533248	hsa-miR-6516-5p	PAR-CLIP	27292025
MIRT004081	hsa-miR-126-3p	Luciferase reporter assayWestern blottingqRT-PCR	31474826
MIRT715363	hsa-miR-181a-5p	HITS-CLIP	19536157
MIRT715362	hsa-miR-181c-5p	HITS-CLIP	19536157
MIRT715361	hsa-miR-181d-5p	HITS-CLIP	19536157
MIRT715360	hsa-miR-4262	HITS-CLIP	19536157
MIRT715359	hsa-miR-181b-5p	HITS-CLIP	19536157
MIRT715358	hsa-miR-506-5p	HITS-CLIP	19536157
MIRT715357	hsa-miR-211-3p	HITS-CLIP	19536157
MIRT715356	hsa-miR-4270	HITS-CLIP	19536157
MIRT715355	hsa-miR-4441	HITS-CLIP	19536157
MIRT715354	hsa-miR-6754-5p	HITS-CLIP	19536157
MIRT715353	hsa-miR-3691-3p	HITS-CLIP	19536157
MIRT715352	hsa-miR-3127-5p	HITS-CLIP	19536157
MIRT504357	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT504356	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT504355	hsa-miR-6074	HITS-CLIP	21572407
MIRT707385	hsa-miR-3183	HITS-CLIP	21572407
MIRT707384	hsa-miR-4723-3p	HITS-CLIP	21572407
MIRT707383	hsa-miR-6769b-3p	HITS-CLIP	21572407
MIRT707382	hsa-miR-136-5p	HITS-CLIP	21572407
MIRT707381	hsa-miR-6845-3p	HITS-CLIP	21572407
MIRT707380	hsa-miR-7110-3p	HITS-CLIP	21572407
MIRT504354	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT504353	hsa-miR-130a-5p	HITS-CLIP	21572407
MIRT504352	hsa-miR-23a-3p	HITS-CLIP	21572407
MIRT504351	hsa-miR-23b-3p	HITS-CLIP	21572407
MIRT504350	hsa-miR-23c	HITS-CLIP	21572407
MIRT504356	hsa-miR-5011-5p	HITS-CLIP	21572407
MIRT504355	hsa-miR-6074	HITS-CLIP	21572407
MIRT504354	hsa-miR-190a-3p	HITS-CLIP	21572407
MIRT504353	hsa-miR-130a-5p	HITS-CLIP	21572407
MIRT504352	hsa-miR-23a-3p	HITS-CLIP	21572407
MIRT504351	hsa-miR-23b-3p	HITS-CLIP	21572407
MIRT504350	hsa-miR-23c	HITS-CLIP	21572407
MIRT504357	hsa-miR-1277-5p	HITS-CLIP	21572407
MIRT504355	hsa-miR-6074	HITS-CLIP	23313552
MIRT504354	hsa-miR-190a-3p	HITS-CLIP	23313552
MIRT504353	hsa-miR-130a-5p	HITS-CLIP	23313552
MIRT504352	hsa-miR-23a-3p	HITS-CLIP	23313552
MIRT504351	hsa-miR-23b-3p	HITS-CLIP	23313552
MIRT504350	hsa-miR-23c	HITS-CLIP	23313552
MIRT504357	hsa-miR-1277-5p	HITS-CLIP	23313552
MIRT635479	hsa-miR-548ae-3p	HITS-CLIP	23824327
MIRT635478	hsa-miR-548ah-3p	HITS-CLIP	23824327
MIRT635477	hsa-miR-548aj-3p	HITS-CLIP	23824327
MIRT635476	hsa-miR-548am-3p	HITS-CLIP	23824327
MIRT635475	hsa-miR-548aq-3p	HITS-CLIP	23824327
MIRT635474	hsa-miR-548j-3p	HITS-CLIP	23824327
MIRT635473	hsa-miR-548x-3p	HITS-CLIP	23824327
MIRT619599	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT619598	hsa-miR-519d-5p	HITS-CLIP	23824327
MIRT619599	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT619598	hsa-miR-519d-5p	HITS-CLIP	23824327
MIRT504356	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT504355	hsa-miR-6074	HITS-CLIP	23824327
MIRT504354	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT504353	hsa-miR-130a-5p	HITS-CLIP	23824327
MIRT504352	hsa-miR-23a-3p	HITS-CLIP	23824327
MIRT504351	hsa-miR-23b-3p	HITS-CLIP	23824327
MIRT504350	hsa-miR-23c	HITS-CLIP	23824327
MIRT504357	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT619599	hsa-miR-3145-5p	HITS-CLIP	23824327
MIRT619598	hsa-miR-519d-5p	HITS-CLIP	23824327
MIRT504356	hsa-miR-5011-5p	HITS-CLIP	23824327
MIRT504355	hsa-miR-6074	HITS-CLIP	23824327
MIRT610905	hsa-miR-5092	HITS-CLIP	23824327
MIRT504354	hsa-miR-190a-3p	HITS-CLIP	23824327
MIRT504353	hsa-miR-130a-5p	HITS-CLIP	23824327
MIRT504352	hsa-miR-23a-3p	HITS-CLIP	23824327
MIRT504351	hsa-miR-23b-3p	HITS-CLIP	23824327
MIRT504350	hsa-miR-23c	HITS-CLIP	23824327
MIRT504357	hsa-miR-1277-5p	HITS-CLIP	23824327
MIRT504355	hsa-miR-6074	PAR-CLIP	21572407
MIRT504354	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT504353	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT504352	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT504351	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT504350	hsa-miR-23c	PAR-CLIP	21572407
MIRT504357	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT504356	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT504355	hsa-miR-6074	PAR-CLIP	21572407
MIRT504354	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT504353	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT504352	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT504351	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT504350	hsa-miR-23c	PAR-CLIP	21572407
MIRT504357	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT504356	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT504355	hsa-miR-6074	PAR-CLIP	21572407
MIRT504354	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT504353	hsa-miR-130a-5p	PAR-CLIP	21572407
MIRT504352	hsa-miR-23a-3p	PAR-CLIP	21572407
MIRT504351	hsa-miR-23b-3p	PAR-CLIP	21572407
MIRT504350	hsa-miR-23c	PAR-CLIP	21572407
MIRT504357	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT533259	hsa-miR-186-5p	PAR-CLIP	22012620
MIRT533258	hsa-miR-6856-3p	PAR-CLIP	22012620
MIRT533257	hsa-miR-5694	PAR-CLIP	22012620
MIRT504356	hsa-miR-5011-5p	PAR-CLIP	22012620
MIRT533256	hsa-miR-96-3p	PAR-CLIP	22012620
MIRT533255	hsa-miR-2467-3p	PAR-CLIP	22012620
MIRT533254	hsa-miR-2116-5p	PAR-CLIP	22012620
MIRT533253	hsa-miR-22-5p	PAR-CLIP	22012620
MIRT533252	hsa-miR-6844	PAR-CLIP	22012620
MIRT533251	hsa-miR-1273h-3p	PAR-CLIP	22012620
MIRT533250	hsa-miR-3678-3p	PAR-CLIP	22012620
MIRT533249	hsa-miR-4677-5p	PAR-CLIP	22012620
MIRT533248	hsa-miR-6516-5p	PAR-CLIP	22012620
MIRT504357	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT504355	hsa-miR-6074	PAR-CLIP	23446348
MIRT504354	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT504353	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT504352	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT504351	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT504350	hsa-miR-23c	PAR-CLIP	23446348
MIRT504357	hsa-miR-1277-5p	PAR-CLIP	23446348
MIRT504356	hsa-miR-5011-5p	PAR-CLIP	23446348
MIRT504355	hsa-miR-6074	PAR-CLIP	23446348
MIRT504354	hsa-miR-190a-3p	PAR-CLIP	23446348
MIRT504353	hsa-miR-130a-5p	PAR-CLIP	23446348
MIRT504352	hsa-miR-23a-3p	PAR-CLIP	23446348
MIRT504351	hsa-miR-23b-3p	PAR-CLIP	23446348
MIRT504350	hsa-miR-23c	PAR-CLIP	23446348
MIRT756150	hsa-miR-95-3p	Western blottingqRT-PCR	36467343
MIRT756469	hsa-miR-182-5p	qRT-PCR	38796528
MIRT1483204	hsa-miR-2116	CLIP-seq
MIRT1483205	hsa-miR-4269	CLIP-seq
MIRT1483206	hsa-miR-4514	CLIP-seq
MIRT1483207	hsa-miR-452	CLIP-seq
MIRT1483208	hsa-miR-4676-3p	CLIP-seq
MIRT1483209	hsa-miR-4692	CLIP-seq
MIRT1483210	hsa-miR-4742-5p	CLIP-seq
MIRT1483211	hsa-miR-507	CLIP-seq
MIRT1483212	hsa-miR-557	CLIP-seq
MIRT1483213	hsa-miR-577	CLIP-seq
MIRT1555382	hsa-miR-1825	CLIP-seq
MIRT1555383	hsa-miR-202	CLIP-seq
MIRT1555384	hsa-miR-204	CLIP-seq
MIRT1555385	hsa-miR-211	CLIP-seq
MIRT1555386	hsa-miR-3121-5p	CLIP-seq
MIRT1555387	hsa-miR-3130-5p	CLIP-seq
MIRT1555388	hsa-miR-4287	CLIP-seq
MIRT1555389	hsa-miR-4482	CLIP-seq
MIRT1555390	hsa-miR-4678	CLIP-seq
MIRT1555391	hsa-miR-4685-3p	CLIP-seq
MIRT1555392	hsa-miR-4766-5p	CLIP-seq
MIRT1555393	hsa-miR-4795-3p	CLIP-seq
MIRT2365788	hsa-miR-1207-3p	CLIP-seq
MIRT2365789	hsa-miR-3974	CLIP-seq
MIRT2365790	hsa-miR-545	CLIP-seq
MIRT2659385	hsa-miR-1284	CLIP-seq
MIRT2659386	hsa-miR-3124-3p	CLIP-seq
MIRT1555387	hsa-miR-3130-5p	CLIP-seq
MIRT2659387	hsa-miR-3144-3p	CLIP-seq
MIRT2659388	hsa-miR-3605-3p	CLIP-seq
MIRT2659389	hsa-miR-3678-5p	CLIP-seq
MIRT2659390	hsa-miR-3919	CLIP-seq
MIRT2659391	hsa-miR-3945	CLIP-seq
MIRT2659392	hsa-miR-4253	CLIP-seq
MIRT1555389	hsa-miR-4482	CLIP-seq
MIRT2659393	hsa-miR-4528	CLIP-seq
MIRT2659394	hsa-miR-4712-5p	CLIP-seq
MIRT2659395	hsa-miR-4797-5p	CLIP-seq
MIRT2659396	hsa-miR-494	CLIP-seq
MIRT2659397	hsa-miR-770-5p	CLIP-seq
MIRT2659385	hsa-miR-1284	CLIP-seq
MIRT2659386	hsa-miR-3124-3p	CLIP-seq
MIRT1555387	hsa-miR-3130-5p	CLIP-seq
MIRT2659387	hsa-miR-3144-3p	CLIP-seq
MIRT2659388	hsa-miR-3605-3p	CLIP-seq
MIRT2659389	hsa-miR-3678-5p	CLIP-seq
MIRT2659390	hsa-miR-3919	CLIP-seq
MIRT2659391	hsa-miR-3945	CLIP-seq
MIRT2659392	hsa-miR-4253	CLIP-seq
MIRT1555389	hsa-miR-4482	CLIP-seq
MIRT2659393	hsa-miR-4528	CLIP-seq
MIRT2659394	hsa-miR-4712-5p	CLIP-seq
MIRT2659395	hsa-miR-4797-5p	CLIP-seq
MIRT2659396	hsa-miR-494	CLIP-seq
MIRT2659397	hsa-miR-770-5p	CLIP-seq

Show/Hide all (11)

Transcription factor	Regulation	Reference
EP300	Activation	19281832
HDAC4	Activation	19281832
HOXA9	Unknown	22269951
IKBKB	Repression	18600306
IRF1	Unknown	15265939;22182512
JUN	Activation	16271621
NFKB1	Activation	10329958;10946302;11359843;16271621;16317091;16385502;19281832;19422386;22708120
NFKB1	Unknown	10553096;10833420;16453001
POU2F1	Repression	9694713
RELA	Activation	10329958;10946302;11359843;16317091;16385502;19281832;19422386;22708120
RELA	Unknown	10553096;10833420;16453001;23042817

Show/Hide all (60)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001666	Process	Response to hypoxia	IEA
GO:0002102	Component	Podosome	IDA	15220135
GO:0002544	Process	Chronic inflammatory response	IEA
GO:0005178	Function	Integrin binding	IBA
GO:0005178	Function	Integrin binding	IDA	1377228, 15220135, 23620790
GO:0005178	Function	Integrin binding	IEA
GO:0005178	Function	Integrin binding	IMP	19738201
GO:0005576	Component	Extracellular region	IEA
GO:0005615	Component	Extracellular space	IDA	9290466
GO:0005615	Component	Extracellular space	IEA
GO:0005769	Component	Early endosome	IDA	23474851
GO:0005783	Component	Endoplasmic reticulum	IDA	23474851
GO:0005794	Component	Golgi apparatus	IDA	23474851
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IC	12878595
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0005902	Component	Microvillus	IDA	12082081
GO:0006954	Process	Inflammatory response	IC	9572733
GO:0006954	Process	Inflammatory response	IDA	22970700
GO:0007155	Process	Cell adhesion	IBA
GO:0007155	Process	Cell adhesion	IDA	16809613
GO:0007155	Process	Cell adhesion	IEA
GO:0007157	Process	Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	IDA	1715889
GO:0007159	Process	Leukocyte cell-cell adhesion	IDA	1381355, 1715889, 2688898
GO:0007160	Process	Cell-matrix adhesion	IDA	18308860
GO:0007584	Process	Response to nutrient	IEA
GO:0008131	Function	Primary methylamine oxidase activity	IDA	23474851
GO:0009308	Process	Amine metabolic process	IDA	23474851
GO:0009897	Component	External side of plasma membrane	IDA	1377228
GO:0009986	Component	Cell surface	IDA	1715889, 23474851
GO:0009986	Component	Cell surface	IEA
GO:0010043	Process	Response to zinc ion	IEA
GO:0010212	Process	Response to ionizing radiation	IEA
GO:0016020	Component	Membrane	IEA
GO:0022614	Process	Membrane to membrane docking	IEP	12082081
GO:0030175	Component	Filopodium	IDA	12082081
GO:0030183	Process	B cell differentiation	IC	1715889
GO:0032496	Process	Response to lipopolysaccharide	IEA
GO:0033631	Process	Cell-cell adhesion mediated by integrin	IGI	11078691
GO:0034113	Process	Heterotypic cell-cell adhesion	IGI	11078691
GO:0035094	Process	Response to nicotine	IEA
GO:0035924	Process	Cellular response to vascular endothelial growth factor stimulus	IEA
GO:0042102	Process	Positive regulation of T cell proliferation	IDA	1381355
GO:0042383	Component	Sarcolemma	IEA
GO:0045177	Component	Apical part of cell	IDA	12082081
GO:0045471	Process	Response to ethanol	IEA
GO:0050839	Function	Cell adhesion molecule binding	IDA	1377228
GO:0050839	Function	Cell adhesion molecule binding	IPI	12082081
GO:0050901	Process	Leukocyte tethering or rolling	IDA	18308860
GO:0050901	Process	Leukocyte tethering or rolling	IEP	2688898
GO:0060326	Process	Cell chemotaxis	IEA
GO:0060384	Process	Innervation	IEA
GO:0060945	Process	Cardiac neuron differentiation	IEA
GO:0070062	Component	Extracellular exosome	HDA	23533145
GO:0071065	Component	Alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex	IDA	15220135
GO:0071356	Process	Cellular response to tumor necrosis factor	IEA
GO:0098609	Process	Cell-cell adhesion	IEA
GO:0098631	Function	Cell adhesion mediator activity	IDA	22970700
GO:1904646	Process	Cellular response to amyloid-beta	IGI	11078691

MIM	HGNC	e!Ensembl
192225	12663	ENSG00000162692

P19320

Protein name

Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]

Protein function

Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation (PubMed:31310649). Acts as a major regulator of leukocyte adhesion to the endothelium thr

PDB

1IJ9 , 1VCA , 1VSC

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07679	I-set	25 → 112	Immunoglobulin I-set domain	Domain
PF05790	C2-set	133 → 221	Immunoglobulin C2-set domain	Domain
PF00047	ig	229 → 306	Immunoglobulin domain	Domain
PF07679	I-set	314 → 400	Immunoglobulin I-set domain	Domain
PF05790	C2-set	421 → 509	Immunoglobulin C2-set domain	Domain
PF13927	Ig_3	515 → 583		Domain
PF07679	I-set	605 → 685	Immunoglobulin I-set domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.

Sequence

MPGKMVVILGASNILWIMFAASQAFKIETTPESRYLAQIGDSVSLTCSTTGCESPFFSWR
TQIDSPLNGKVTNEGTTSTLTMNPVSFGNEHSYLCTATCESRKLEKGIQVEIYSFPKDPE
IHLSGPLEAGKPITVKCSVADVYPFDRLEIDLLKGDHLMKSQEFLEDADRKSLETKSLEV
TFTPVIEDIGKVLVCRAKLHIDEMDSVPTVRQAVKELQVYISPKNTVISVNPSTKLQEGG
SVTMTCSSEGLPAPEIFWSKKLDNGNLQHLSGNATLTLIAMRMEDSGIYVCEGVNLIGKN
RKEVELIVQEKPFTVEISPGPRIAAQIGDSVMLTCSVMGCESPSFSWRTQIDSPLSGKVR
SEGTNSTLTLSPVSFENEHSYLCTVTCGHKKLEKGIQVELYSFPRDPEIEMSGGLVNGSS
VTVSCKVPSVYPLDRLEIELLKGETILENIEFLEDTDMKSLENKSLEMTFIPTIEDTGKA
LVCQAKLHIDDMEFEPKQRQSTQTLYVNVAPRDTTVLVSPSSILEEGSSVNMTCLSQGFP
APKILWSRQLPNGELQPLSENATLTLISTKMEDSGVYLCEGINQAGRSRKEVELIIQVTP
KDIKLTAFPSESVKEGDTVIISCTCGNVPETWIILKKKAETGDTVLKSIDGAYTIRKAQL
KDAGVYECESKNKVGSQLRSLTLDVQGRENNKDYFSPELLVLYFASSLIIPAIGMIIYFA
RKANMKGSYSLVEAQKSKV

Sequence length

739

Interactions

View interactions

	KEGG		Reactome
	NF-kappa B signaling pathway Cell adhesion molecules TNF signaling pathway Leukocyte transendothelial migration AGE-RAGE signaling pathway in diabetic complications African trypanosomiasis Malaria Lipid and atherosclerosis Fluid shear stress and atherosclerosis		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Integrin cell surface interactions Interleukin-4 and Interleukin-13 signaling Interferon gamma signaling

VCAM1 (vascular cell adhesion molecule 1)