Gene Gene information from NCBI Gene database.
Entrez ID 741
Gene name Zinc finger HIT-type containing 2
Gene symbol ZNHIT2
Synonyms (NCBI Gene)
C11orf5FON
Chromosome 11
Chromosome location 11q13.1
miRNA miRNA information provided by mirtarbase database.
4
miRTarBase ID miRNA Experiments Reference
MIRT030125 hsa-miR-26b-5p Microarray 19088304
MIRT1542921 hsa-miR-4477a CLIP-seq
MIRT1542922 hsa-miR-4704-3p CLIP-seq
MIRT1542921 hsa-miR-4477a CLIP-seq
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
3
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 28514442, 28561026, 32296183, 33961781, 34131137
GO:0008270 Function Zinc ion binding IEA
GO:0046872 Function Metal ion binding IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604575 1177 ENSG00000174276
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9UHR6
Protein name Zinc finger HIT domain-containing protein 2 (Protein FON)
Protein function May act as a bridging factor mediating the interaction between the R2TP/Prefoldin-like (R2TP/PFDL) complex and U5 small nuclear ribonucleoprotein (U5 snRNP) (PubMed:28561026). Required for the interaction of R2TP complex subunit RPAP3 and prefol
PDB 1X4S
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04438 zf-HIT 3 36 HIT zinc finger Domain
Tissue specificity TISSUE SPECIFICITY: Low expression in most tissues; highly expressed in testis. {ECO:0000269|PubMed:10602999}.
Sequence
MEPAGPCGFCPAGEVQPARYTCPRCNAPYCSLRCYRTHGTCAENFYRDQVLGELRGCSAP
PSRLASALRRLRQQRETEDEPGEAGLSSGPAPGGLSGLWERLAPGEKAAFERLLSRGEAG
RLLPPWRPWWWNRGAGPQLLEELDNAPGSDAAELELAPARTPPDSVKDASAAEPAAAERV
LGDVPGACTPVVPTRIPAIVSLSRGPVSPLVRFQLPNVLFAYAHTLALYHGGDDALLSDF
CATLLGVSGALGAQQVFASAEEALQAAAHVLEAGEHPPGPLGTRGAMHEVARILLGEGPT
NQKGYTLAALGDLAQTLGRARKQAVAREERDHLYRARKKCQFLLAWTNENEAALTPLALD
CARAHQAHAVVAEEVAALTGELERLWGGPVPPAPRTLIEELPS
Sequence length 403
Interactions View interactions