SCGB1A1 (secretoglobin family 1A member 1)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
7356
Gene name Gene Name - the full gene name approved by the HGNC.
Secretoglobin family 1A member 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SCGB1A1
Synonyms (NCBI Gene) Gene synonyms aliases
CC10, CC16, CCPBP, CCSP, UGB, UP-1, UP1
Chromosome Chromosome number
11
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
11q12.3
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defec
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(12)
miRTarBase ID miRNA Experiments Reference
MIRT1329344 hsa-miR-1273g CLIP-seq
MIRT1329345 hsa-miR-299-5p CLIP-seq
MIRT1329346 hsa-miR-4708-5p CLIP-seq
MIRT1329347 hsa-miR-4709-3p CLIP-seq
MIRT2097669 hsa-miR-2110 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(30)
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0005515 Function Protein binding IPI 16423471, 18243143, 21516116, 25416956, 31515488, 32296183, 32814053
GO:0005615 Component Extracellular space IBA 21873635
GO:0005615 Component Extracellular space IDA 21805676
GO:0005635 Component Nuclear envelope IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
192020 12523 ENSG00000149021
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID P11684
Protein name Uteroglobin (Club cell phospholipid-binding protein) (CCPBP) (Club cells 10 kDa secretory protein) (CC10) (Secretoglobin family 1A member 1) (Urinary protein 1) (UP-1) (UP1) (Urine protein 1)
Protein function Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.
PDB 7VF3 , 7VG7
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01099 Uteroglobin 1 → 90 Uteroglobin family Domain
Tissue specificity TISSUE SPECIFICITY: Club cells (nonciliated cells of the surface epithelium of the pulmonary airways).
Sequence
Sequence length 91
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (1)
Unknown
Disease term Disease name Evidence References Source
Chronic obstructive pulmonary disease Chronic Obstructive Airway Disease 23144326 ClinVar
Show/Hide Text Mining Associations (61)
Associations from Text Mining
Disease Name Relationship Type References
Acute Lung Injury Associate 32184583
Adenocarcinoma of Lung Associate 39364403
Airway Obstruction Associate 17624750
Airway Remodeling Associate 17624750
Arthritis Rheumatoid Associate 20037209
Asthma Associate 31322430, 32762031, 36352422, 9643286
Asthma Inhibit 36066606
Atrophy Stimulate 34928497
Breast Neoplasms Associate 14521461
Bronchial Hyperreactivity Associate 28146340