Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
729993
Gene name Gene Name - the full gene name approved by the HGNC.
Shisa family member 9
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
SHISA9
Synonyms (NCBI Gene) Gene synonyms aliases
CKAMP44
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16p13.12
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT570790 hsa-miR-3662 HITS-CLIP 23313552
MIRT570791 hsa-miR-8084 HITS-CLIP 23313552
MIRT699616 hsa-miR-7153-3p HITS-CLIP 23313552
MIRT570789 hsa-miR-1272 HITS-CLIP 23313552
MIRT699615 hsa-miR-4789-5p HITS-CLIP 23313552
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0008328 Component Ionotropic glutamate receptor complex ISS
GO:0014069 Component Postsynaptic density IBA 21873635
GO:0030165 Function PDZ domain binding IEA
GO:0032281 Component AMPA glutamate receptor complex IBA 21873635
GO:0032591 Component Dendritic spine membrane IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
613346 37231 ENSG00000237515
Protein
UniProt ID B4DS77
Protein name Protein shisa-9
Protein function Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses (By similarity). {ECO
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF13908 Shisa 71 260 Wnt and FGF inhibitory regulator Family
Sequence
MRRVLRLLLGCFLTELCARVCRAQERAGHGQLAQLGGVLLLAGGNRSGAASGEASEGAEA
SDAPPTRAPTPDFCRGYFDVMGQWDPPFNCSSGDFIFCCGTCGFRFCCTFKKRRLNQSTC
TNYDTPLWLNTGKPPARKDDPLHDPTKDKTNLIVYIICGVVAVMVLVGIFTKLGLEKAHR
PQREHMSRALADVMRPQGHCNTDHMERDLNIVVHVQHYENMDTRTPINNLHATQMNNAVP
TSPLLQQMGHPHSYPNLGQI
SNPYEQQPPGKELNKYASLKAVGSSDGDWAVSTLKSPKAD
KVNDDFYTKRRHLAELAAKGNLPLHPVRVEDEPRAFSPEHGPAKQNGQKSRTNKMPPHPL
AYTSTTNFKGWDPNEQSLRRQAYSNKGKLGTAETGSSDPLGTRPQHYPPPQPYFITNSKT
EVTV
Sequence length 424
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Schizophrenia Schizophrenia rs13447324, rs387906932, rs387906933, rs863223354, rs863223355, rs776061422, rs863223349, rs748809996, rs759748655, rs863223353, rs863223350, rs863223356, rs781821239, rs863223348, rs863223346
View all (12 more)
26198764
Unknown
Disease term Disease name Evidence References Source
Mental depression Major Depressive Disorder 30718901, 29700475 ClinVar
Neuroticism Neuroticism GWAS
Periodontitis Periodontitis GWAS
Sjogren-Larsson Syndrome Sjogren-Larsson Syndrome GWAS
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 35865652
Carcinoma Pancreatic Ductal Associate 33593879
Muscular Atrophy Spinal Associate 19396477