TUFT1 (tuftelin 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7286 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Tuftelin 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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TUFT1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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WHSF |
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Chromosome
Chromosome number
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1 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1q21.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Tuftelin is an acidic protein that is thought to play a role in dental enamel mineralization and is implicated in caries susceptibility. It is also thought to be involved with adaptation to hypoxia, mesenchymal stem cell function, and neurotrophin nerve g |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||
| UniProt ID | Q9NNX1 | |
| Protein name | Tuftelin | |
| Protein function | Involved in the structural organization of the epidermis (PubMed:36689522). Involved in the mineralization and structural organization of enamel. | |
| Family and domains | ||
| Tissue specificity | TISSUE SPECIFICITY: Expressed in the epidermis (at protein level) (PubMed:36689522). Present in the extracellular enamel and is mainly associated with the crystal component. {ECO:0000269|PubMed:1874744, ECO:0000269|PubMed:36689522}. | |
| Sequence |
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| Sequence length | 390 | |
| Interactions | View interactions | |
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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