KRTAP4-8 (keratin associated protein 4-8)

Gene

• Entrez ID: 728224
• Gene name: Keratin associated protein 4-8
• Gene symbol: KRTAP4-8
• Synonyms (NCBI Gene): KAP4.8, KRTAP4.8
• Chromosome: 17
• Chromosome location: 17q21.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT1102086	hsa-miR-186	CLIP-seq
MIRT1102087	hsa-miR-3136-5p	CLIP-seq
MIRT1102088	hsa-miR-3660	CLIP-seq
MIRT1102089	hsa-miR-3929	CLIP-seq
MIRT1102090	hsa-miR-4419b	CLIP-seq
MIRT1102091	hsa-miR-4439	CLIP-seq
MIRT1102092	hsa-miR-4478	CLIP-seq
MIRT1102093	hsa-miR-4513	CLIP-seq
MIRT1102094	hsa-miR-4526	CLIP-seq
MIRT1102095	hsa-miR-4659a-5p	CLIP-seq
MIRT1102096	hsa-miR-4659b-5p	CLIP-seq
MIRT1102097	hsa-miR-4766-5p	CLIP-seq
MIRT1102098	hsa-miR-488	CLIP-seq
MIRT1102099	hsa-miR-7	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005829	Component	Cytosol	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005882	Component	Intermediate filament	IEA
GO:0042633	Process	Hair cycle	IBA
GO:0042633	Process	Hair cycle	IDA	21916889
GO:0045095	Component	Keratin filament	IEA

Other IDs

• MIM: HGNC
• HGNC: N/A
• e!Ensembl: HGNC

Protein

• UniProt ID: Q9BYQ9
• Protein name: Keratin-associated protein 4-8 (Keratin-associated protein 4.8) (Ultrahigh sulfur keratin-associated protein 4.8)
• Protein function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their e
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF13885	Keratin_B2_2	1 → 53	Keratin, high sulfur B2 protein	Family
  PF13885	Keratin_B2_2	34 → 78	Keratin, high sulfur B2 protein	Family
  PF13885	Keratin_B2_2	45 → 93	Keratin, high sulfur B2 protein	Family
  PF13885	Keratin_B2_2	79 → 123	Keratin, high sulfur B2 protein	Family
  PF13885	Keratin_B2_2	109 → 160	Keratin, high sulfur B2 protein	Family
  PF13885	Keratin_B2_2	150 → 185	Keratin, high sulfur B2 protein	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in the hair follicles. {ECO:0000269|PubMed:15955084}.
• Sequence:

  MVNSCCGSVCSDQGCGQDLCQETCCCPSCCQTTCCRTTCYRPSYSVSCCCRPQCCQSVCC
  QPTCCRPSCCVSSCCKPQCCQSVCCQPTCCHPSCCISSCCRPSCCVSSCCKPQCCQSVCC
  QPNCCRPSCSISSCCRPSCCESSCCRPCCCLRPVCGRVSCHTTCYRPACVISTCPRPVCC
  ASSCC

• Sequence length: 185

Pathways

Reactome:

Keratinization