TTN (titin)

Gene

• Entrez ID: 7273
• Gene name: Titin
• Gene symbol: TTN
• Synonyms (NCBI Gene): CMD1G, CMH9, CMPD4, CMYO5, CMYP5, EOMFC, HMERF, LGMD2J, LGMDR10, MYLK5, SALMY, TMD
• Chromosome: 2
• Chromosome location: 2q31.2
• Summary: This gene encodes a large abundant protein of striated muscle. The product of this gene is divided into two regions, a N-terminal I-band and a C-terminal A-band. The I-band, which is the elastic part of the molecule, contains two regions of tandem immunog

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs2099130	A>G	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, intron variant, missense variant, genic downstream transcript variant
rs6716782	T>G	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, splice acceptor variant, genic upstream transcript variant, intron variant
rs28933405	C>A,T	Pathogenic	Coding sequence variant, genic upstream transcript variant, missense variant
rs34706299	A>G	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, missense variant
rs55634230	A>C	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, missense variant
rs55914517	C>A,T	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, missense variant
rs56373393	C>T	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, missense variant
rs61232800	T>C,G	Benign, likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, synonymous variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72647842	G>A,C,T	Conflicting-interpretations-of-pathogenicity, likely-benign, benign-likely-benign	Coding sequence variant, genic upstream transcript variant, synonymous variant
rs72647861	C>A	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant, genic upstream transcript variant
rs72647868	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant, genic upstream transcript variant
rs72647870	C>G,T	Conflicting-interpretations-of-pathogenicity, likely-benign, benign-likely-benign	Coding sequence variant, missense variant, genic upstream transcript variant
rs72647884	G>A	Likely-pathogenic, uncertain-significance	Coding sequence variant, missense variant, genic upstream transcript variant
rs72647894	C>G,T	Benign, conflicting-interpretations-of-pathogenicity, likely-benign, uncertain-significance	Coding sequence variant, missense variant, genic upstream transcript variant
rs72647897	A>G	Likely-benign, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, missense variant, intron variant
rs72647901	G>A,T	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, missense variant, intron variant
rs72647902	C>A,T	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, missense variant, intron variant
rs72648913	C>T	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, missense variant, intron variant
rs72648923	C>A,G,T	Benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648925	G>A,C	Conflicting-interpretations-of-pathogenicity, likely-benign, benign-likely-benign	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648929	C>G,T	Likely-benign, conflicting-interpretations-of-pathogenicity, benign, uncertain-significance, benign-likely-benign	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648930	T>G	Conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648936	G>A,T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, synonymous variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648940	C>A	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648942	T>C	Benign, uncertain-significance, likely-benign, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648945	T>C	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648949	G>C,T	Benign, conflicting-interpretations-of-pathogenicity, uncertain-significance, benign-likely-benign	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648953	G>T	Benign, conflicting-interpretations-of-pathogenicity, benign-likely-benign	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648958	C>G,T	Conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648965	T>C	Conflicting-interpretations-of-pathogenicity, likely-benign, benign-likely-benign	Genic upstream transcript variant, genic downstream transcript variant, intron variant
rs72648969	C>T	Benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648971	C>T	Conflicting-interpretations-of-pathogenicity, benign-likely-benign	Genic downstream transcript variant, synonymous variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648973	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648975	G>T	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, intron variant
rs72648981	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648989	T>C	Conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648990	G>A,C	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648994	T>C	Benign-likely-benign, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72648997	G>A,T	Conflicting-interpretations-of-pathogenicity, uncertain-significance, benign-likely-benign	Missense variant, genic downstream transcript variant, synonymous variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72650011	G>A	Benign, uncertain-significance, likely-benign, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72650031	G>A,T	Benign, conflicting-interpretations-of-pathogenicity, likely-benign, benign-likely-benign	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72650034	C>G,T	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72650035	T>C	Uncertain-significance, likely-benign, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72650040	C>G	Likely-benign, conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs72650064	G>T	Uncertain-significance, likely-benign, conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant, genic downstream transcript variant, intron variant
rs72677223	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign, benign-likely-benign	Coding sequence variant, genic downstream transcript variant, synonymous variant
rs72677225	C>A	Benign, conflicting-interpretations-of-pathogenicity, benign-likely-benign	Coding sequence variant, missense variant, genic downstream transcript variant
rs111671438	C>A,T	Uncertain-significance, conflicting-interpretations-of-pathogenicity, likely-benign	Intron variant, genic downstream transcript variant, missense variant, coding sequence variant, genic upstream transcript variant
rs112009206	A>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, genic downstream transcript variant, missense variant, coding sequence variant, genic upstream transcript variant
rs115825044	G>A,C,T	Conflicting-interpretations-of-pathogenicity, likely-benign	Missense variant, coding sequence variant, genic downstream transcript variant
rs117551279	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance, likely-benign	Missense variant, coding sequence variant, intron variant, genic downstream transcript variant, genic upstream transcript variant
rs138060032	G>A	Uncertain-significance, pathogenic, likely-benign	Genic upstream transcript variant, coding sequence variant, missense variant
rs138331646	C>G,T	Conflicting-interpretations-of-pathogenicity, uncertain-significance, likely-benign, benign-likely-benign	Coding sequence variant, synonymous variant, genic upstream transcript variant
rs138788406	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign	Coding sequence variant, synonymous variant, genic upstream transcript variant
rs138853909	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance, likely-benign	Missense variant, genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, intron variant
rs139486133	A>G	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, intron variant, missense variant, coding sequence variant
rs139504522	G>A	Conflicting-interpretations-of-pathogenicity, uncertain-significance, likely-benign	Coding sequence variant, missense variant, genic upstream transcript variant
rs139517732	C>T	Pathogenic	Coding sequence variant, missense variant, genic upstream transcript variant
rs139790668	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, intron variant
rs140064945	G>A,T	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, missense variant, coding sequence variant
rs140640738	T>G	Benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Missense variant, genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, intron variant
rs140664731	G>A,T	Conflicting-interpretations-of-pathogenicity, likely-benign	Coding sequence variant, missense variant, genic upstream transcript variant
rs140743001	G>A	Conflicting-interpretations-of-pathogenicity, uncertain-significance, likely-pathogenic	Genic downstream transcript variant, coding sequence variant, stop gained
rs141027782	A>G	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, missense variant, coding sequence variant
rs141258018	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance, benign-likely-benign	Coding sequence variant, missense variant, genic upstream transcript variant
rs142132973	A>G	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, intron variant, missense variant, coding sequence variant
rs142304137	T>C	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, intron variant, missense variant, coding sequence variant
rs142414432	C>A,T	Conflicting-interpretations-of-pathogenicity, uncertain-significance, likely-benign	Coding sequence variant, missense variant, genic upstream transcript variant
rs142951505	C>T	Benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Coding sequence variant, missense variant, genic upstream transcript variant
rs143845692	A>G	Conflicting-interpretations-of-pathogenicity, uncertain-significance, likely-benign	Genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, synonymous variant, intron variant
rs144025230	C>G,T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, intron variant
rs144209883	A>G,T	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, missense variant, coding sequence variant
rs144214844	T>C	Conflicting-interpretations-of-pathogenicity, likely-benign	Coding sequence variant, synonymous variant, genic upstream transcript variant
rs144639994	C>A,T	Benign-likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant
rs144690298	C>A,T	Likely-benign, conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant, stop gained, intron variant, genic upstream transcript variant
rs144750850	A>G	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, synonymous variant
rs144848584	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, coding sequence variant, genic downstream transcript variant
rs145039979	G>A	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, coding sequence variant
rs145581345	T>C	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, coding sequence variant, intron variant
rs145649088	G>A,C	Likely-pathogenic, likely-benign, uncertain-significance	Genic upstream transcript variant, missense variant, coding sequence variant, stop gained
rs145932311	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, coding sequence variant, intron variant
rs146057575	T>C	Benign-likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, coding sequence variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs146400809	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity, benign	Missense variant, coding sequence variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs146627500	T>C	Conflicting-interpretations-of-pathogenicity, benign, uncertain-significance	Missense variant, coding sequence variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs146636599	C>G	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, coding sequence variant
rs146690035	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant, intron variant
rs146828735	T>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs146970027	T>C	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, coding sequence variant
rs147314430	C>G	Likely-benign, not-provided, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant, intron variant
rs147603843	C>G,T	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, synonymous variant
rs147879266	C>T	Pathogenic, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant, genic downstream transcript variant
rs148115514	C>G,T	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant, intron variant
rs148140756	G>A,T	Likely-benign, conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant, genic downstream transcript variant, intron variant
rs148164929	G>A	Conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs148169214	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant
rs148269839	A>C,G	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, coding sequence variant
rs148631577	T>C	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, coding sequence variant
rs148920986	C>A,T	Likely-pathogenic, uncertain-significance	Genic upstream transcript variant, missense variant, coding sequence variant
rs149059189	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, coding sequence variant, genic downstream transcript variant
rs149470241	T>A	Conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs149523263	G>A,C	Likely-benign, conflicting-interpretations-of-pathogenicity, benign, uncertain-significance	Missense variant, synonymous variant, coding sequence variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs149748934	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant, intron variant
rs149755500	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, coding sequence variant
rs149855485	C>T	Conflicting-interpretations-of-pathogenicity, benign, uncertain-significance	Missense variant, coding sequence variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs149910892	G>A	Conflicting-interpretations-of-pathogenicity, benign	Synonymous variant, coding sequence variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs150231219	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, coding sequence variant
rs150544093	C>T	Uncertain-significance, benign-likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, intron variant, synonymous variant
rs151253841	G>A,C	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, genic upstream transcript variant, coding sequence variant
rs181206334	G>A,T	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, missense variant, intron variant, synonymous variant
rs182934463	T>G	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, intron variant, synonymous variant
rs183220684	T>C	Conflicting-interpretations-of-pathogenicity	Upstream transcript variant, genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, missense variant, intron variant
rs183245562	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, missense variant, coding sequence variant
rs183328495	G>A	Uncertain-significance, likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, intron variant, synonymous variant
rs183336802	T>C	Benign-likely-benign, conflicting-interpretations-of-pathogenicity	Synonymous variant, genic upstream transcript variant, coding sequence variant
rs184153985	T>G	Uncertain-significance, likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, missense variant, coding sequence variant, intron variant
rs184307461	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, intron variant, synonymous variant
rs184412722	T>C	Benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, missense variant, coding sequence variant, intron variant
rs184713215	T>C	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, missense variant, coding sequence variant
rs184888200	A>G,T	Uncertain-significance, likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, genic downstream transcript variant
rs185962498	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, missense variant, genic upstream transcript variant, coding sequence variant, intron variant
rs186624523	C>T	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, missense variant, genic upstream transcript variant, coding sequence variant, intron variant
rs187365142	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant
rs187703540	C>T	Likely-benign, benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, missense variant
rs188878341	C>A,G,T	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, missense variant, genic upstream transcript variant, coding sequence variant, intron variant
rs189127014	G>A,T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, missense variant, genic upstream transcript variant, coding sequence variant, intron variant
rs189286381	C>A,T	Benign-likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, missense variant, genic upstream transcript variant, coding sequence variant, intron variant
rs189951108	C>T	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, missense variant, genic upstream transcript variant, coding sequence variant, intron variant
rs190192954	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, missense variant, genic upstream transcript variant, coding sequence variant, intron variant
rs190461403	T>C	Likely-benign, conflicting-interpretations-of-pathogenicity	Coding sequence variant, intron variant, missense variant, genic downstream transcript variant
rs190604150	C>T	Likely-benign, benign-likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, genic upstream transcript variant, synonymous variant, coding sequence variant, intron variant
rs190636272	T>C	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, missense variant, genic upstream transcript variant, coding sequence variant, intron variant
rs191699632	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, intron variant, genic downstream transcript variant, missense variant
rs191708454	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, missense variant
rs191968963	A>G	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs192408585	A>C,T	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant, genic upstream transcript variant
rs192766485	G>A,T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, missense variant
rs192857526	G>C	Benign-likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, synonymous variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs199546417	C>G,T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, synonymous variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs199557654	T>C	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs199565715	A>G	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, genic upstream transcript variant, splice donor variant
rs199576800	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, synonymous variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs199620003	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs199793620	G>A,C	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs199951296	A>G	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, genic upstream transcript variant
rs200061856	A>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200103997	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200118743	C>G	Benign-likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200161147	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200204761	T>G	Conflicting-interpretations-of-pathogenicity, benign	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200213832	G>C	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200359082	G>A,C	Conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200445568	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Coding sequence variant, genic downstream transcript variant, missense variant
rs200459347	G>A,C,T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200593368	G>A	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200594798	T>C	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200760091	T>G	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, intron variant, genic upstream transcript variant, missense variant
rs200792058	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200821070	T>A,C	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant, genic upstream transcript variant
rs200840285	T>A	Benign-likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, upstream transcript variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200941841	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200953966	G>A	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, intron variant, genic upstream transcript variant, missense variant
rs200972189	C>A,G	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs200992277	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity, benign	Coding sequence variant, genic downstream transcript variant, intron variant, missense variant
rs201035457	C>G,T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, intron variant, missense variant
rs201046911	C>G,T	Conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201057307	G>C	Pathogenic, uncertain-significance, conflicting-interpretations-of-pathogenicity, benign	Coding sequence variant, genic downstream transcript variant, missense variant
rs201089861	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Coding sequence variant, synonymous variant, genic upstream transcript variant
rs201129413	A>G	Benign-likely-benign, likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, synonymous variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201257644	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, missense variant
rs201263441	C>T	Benign-likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201390600	A>C,G	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, synonymous variant, missense variant
rs201394117	C>A,T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201395913	T>A,C	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, synonymous variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201418615	C>T	Conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201437752	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201523784	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201565932	T>C	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201571580	C>A,T	Benign-likely-benign, likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201611946	A>C,G	Conflicting-interpretations-of-pathogenicity	Intron variant, genic upstream transcript variant
rs201625116	A>G,T	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, synonymous variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201653851	G>A	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201728165	C>A	Conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201738153	G>A,T	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201744218	G>C,T	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201797790	C>T	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, intron variant, missense variant
rs201810836	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201837864	A>G	Likely-benign, conflicting-interpretations-of-pathogenicity	Coding sequence variant, synonymous variant, genic upstream transcript variant
rs201857541	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, missense variant
rs201888760	G>A	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs201944202	C>A	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, missense variant
rs201991864	G>A	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs202014478	C>T	Benign-likely-benign, likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs202089818	G>A	Benign-likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, synonymous variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs202160275	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity, uncertain-significance	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs202234172	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant, genic upstream transcript variant, splice acceptor variant
rs267607155	A>G,T	Likely-pathogenic, pathogenic	Coding sequence variant, genic upstream transcript variant, missense variant
rs267607157	G>A	Pathogenic	Coding sequence variant, genic upstream transcript variant, missense variant
rs267607158	G>A	Pathogenic	Intron variant, stop gained, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs367648529	C>T	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, genic upstream transcript variant
rs367821526	T>C	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, synonymous variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs367826445	C>A,T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs367888853	T>C	Conflicting-interpretations-of-pathogenicity	Intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs368005198	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, synonymous variant
rs368056479	T>C	Likely-benign, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, intron variant, missense variant
rs368155350	C>A	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, synonymous variant
rs368282893	C>T	Likely-pathogenic, uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, missense variant
rs368327166	TCT>-,TCTTCT	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity, benign	Inframe insertion, intron variant, inframe deletion, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs368548209	G>A,T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, genic upstream transcript variant
rs368698752	A>C	Conflicting-interpretations-of-pathogenicity	Intron variant, synonymous variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs368770038	C>T	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, missense variant
rs368781863	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, synonymous variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs368967197	C>A,T	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, missense variant
rs369095270	C>A,T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs369275615	G>A,T	Conflicting-interpretations-of-pathogenicity, likely-benign, uncertain-significance	Genic upstream transcript variant, intron variant, missense variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs369365087	A>G	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs369385294	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs369434563	C>T	Conflicting-interpretations-of-pathogenicity	Synonymous variant, genic downstream transcript variant, coding sequence variant
rs369508943	G>A	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs369594816	T>C	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant
rs369739111	C>T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs369800903	C>T	Benign-likely-benign, conflicting-interpretations-of-pathogenicity	Synonymous variant, genic downstream transcript variant, coding sequence variant
rs369933152	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs370208081	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs370266918	G>A,T	Conflicting-interpretations-of-pathogenicity, benign, likely-benign	Genic upstream transcript variant, intron variant, missense variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs370548693	G>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs370812788	A>C	Conflicting-interpretations-of-pathogenicity, likely-benign, uncertain-significance	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs370903846	C>A,T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs370912401	G>T	Likely-pathogenic, uncertain-significance	Genic upstream transcript variant, stop gained, intron variant, genic downstream transcript variant, coding sequence variant
rs370973715	C>T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs371121439	A>G	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, genic downstream transcript variant, intron variant
rs371318311	G>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, intron variant
rs371447978	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, synonymous variant, coding sequence variant
rs371452173	C>T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs371455094	G>A,T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs371542947	G>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs371596417	A>G	Likely-pathogenic, uncertain-significance	Genic upstream transcript variant, splice donor variant
rs371687650	C>A,T	Conflicting-interpretations-of-pathogenicity, likely-benign, uncertain-significance	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs371725574	C>T	Likely-pathogenic, uncertain-significance	Genic upstream transcript variant, intron variant, splice acceptor variant, genic downstream transcript variant
rs372124201	C>T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs372166634	C>T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic downstream transcript variant, intron variant
rs372264428	G>A,T	Conflicting-interpretations-of-pathogenicity, benign	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs372277017	G>A	Pathogenic, uncertain-significance	Genic upstream transcript variant, stop gained, intron variant, genic downstream transcript variant, coding sequence variant
rs372382546	G>A	Conflicting-interpretations-of-pathogenicity, benign	Synonymous variant, genic downstream transcript variant, coding sequence variant
rs372392376	A>C	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs372528823	C>A,T	Benign-likely-benign, conflicting-interpretations-of-pathogenicity, likely-benign, uncertain-significance	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs372997298	C>A,T	Benign-likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs373065549	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign, uncertain-significance	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs373083865	C>T	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs373179717	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs373223049	A>G	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs373429851	T>C	Conflicting-interpretations-of-pathogenicity	Synonymous variant, intron variant, coding sequence variant, genic downstream transcript variant
rs373491468	C>A,T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic downstream transcript variant, coding sequence variant, missense variant
rs373496180	G>C	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs373636988	A>T	Conflicting-interpretations-of-pathogenicity, benign, likely-benign	Genic downstream transcript variant, intron variant
rs373815877	C>T	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, intron variant, synonymous variant, upstream transcript variant, coding sequence variant
rs374408615	A>G	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs374419129	T>G	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic downstream transcript variant, coding sequence variant, missense variant
rs374449452	G>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs374479775	C>G	Conflicting-interpretations-of-pathogenicity, benign	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs374509926	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, synonymous variant, coding sequence variant
rs374615369	C>T	Likely-pathogenic, uncertain-significance	Genic upstream transcript variant, coding sequence variant, missense variant
rs374620001	G>A	Conflicting-interpretations-of-pathogenicity, benign, uncertain-significance	Genic upstream transcript variant, coding sequence variant, missense variant
rs374631591	A>G	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs374683153	C>G,T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic downstream transcript variant, coding sequence variant, missense variant
rs375009631	T>C	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, genic downstream transcript variant, intron variant
rs375022009	G>A	Benign-likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs375083775	G>A,T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs375103237	C>T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs375417155	A>G	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, intron variant, genic downstream transcript variant, coding sequence variant
rs375448572	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, synonymous variant, coding sequence variant
rs375474669	C>A,T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic downstream transcript variant, coding sequence variant, missense variant
rs375603989	G>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs376037792	C>T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant, coding sequence variant
rs376527094	A>C,G	Conflicting-interpretations-of-pathogenicity, benign-likely-benign	Genic upstream transcript variant, coding sequence variant, missense variant, synonymous variant
rs376744914	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, genic downstream transcript variant, synonymous variant, intron variant
rs376820575	A>G	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, genic downstream transcript variant, synonymous variant, intron variant
rs376823283	C>A,G,T	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant, genic downstream transcript variant, intron variant
rs376874956	C>G,T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant, genic downstream transcript variant, intron variant
rs377042940	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant, genic downstream transcript variant, intron variant
rs377232641	TCT>-	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, genic downstream transcript variant, intron variant, inframe deletion
rs377556808	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, genic downstream transcript variant, synonymous variant, intron variant
rs397517481	C>A,T	Likely-pathogenic	Genic upstream transcript variant, intron variant, splice donor variant, genic downstream transcript variant
rs397517486	G>A	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, coding sequence variant, stop gained
rs397517497	C>T	Uncertain-significance, likely-pathogenic	Genic upstream transcript variant, intron variant, splice donor variant
rs397517501	A>G	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, genic downstream transcript variant
rs397517521	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, genic downstream transcript variant
rs397517527	C>T	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant, genic downstream transcript variant, intron variant
rs397517540	C>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, genic downstream transcript variant
rs397517547	G>A	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, stop gained
rs397517565	T>-	Uncertain-significance, likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs397517570	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, missense variant
rs397517573	C>G,T	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant, genic downstream transcript variant
rs397517576	G>-	Likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs397517580	G>A	Uncertain-significance, likely-pathogenic	Stop gained, coding sequence variant, genic downstream transcript variant
rs397517663	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant
rs397517825	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity, benign	Genic upstream transcript variant, missense variant, coding sequence variant, genic downstream transcript variant, intron variant
rs397517827	G>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant, genic downstream transcript variant, intron variant
rs397517829	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant, genic downstream transcript variant, intron variant
rs397517830	C>A,T	Uncertain-significance, likely-pathogenic	Stop gained, genic upstream transcript variant, missense variant, coding sequence variant, genic downstream transcript variant, intron variant
rs398124445	T>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant, genic downstream transcript variant
rs398124450	T>C	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, coding sequence variant, synonymous variant, genic downstream transcript variant
rs528853682	G>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, synonymous variant
rs532102837	G>A,T	Likely-benign, uncertain-significance, conflicting-interpretations-of-pathogenicity, benign	Genic upstream transcript variant, missense variant, coding sequence variant, genic downstream transcript variant, intron variant
rs533384820	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign	Missense variant, coding sequence variant, genic upstream transcript variant
rs535281449	G>A,T	Conflicting-interpretations-of-pathogenicity	Synonymous variant, intron variant, missense variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs542965530	C>T	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, intron variant
rs543102139	C>T	Conflicting-interpretations-of-pathogenicity, likely-benign, uncertain-significance	Genic downstream transcript variant, missense variant, coding sequence variant
rs547338168	G>A,T	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, synonymous variant, genic downstream transcript variant, genic upstream transcript variant, coding sequence variant
rs550441902	C>G	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Missense variant, genic upstream transcript variant, coding sequence variant
rs551811137	T>C	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant, missense variant, coding sequence variant
rs553548392	T>C	Conflicting-interpretations-of-pathogenicity	Intron variant, genic downstream transcript variant, missense variant, genic upstream transcript variant, coding sequence variant
rs557125278	A>G	Benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, missense variant, coding sequence variant
rs557526069	C>A,T	Pathogenic	Genic upstream transcript variant, intron variant, genic downstream transcript variant, missense variant, coding sequence variant, stop gained
rs561557554	C>G,T	Conflicting-interpretations-of-pathogenicity	Intron variant, genic downstream transcript variant, missense variant, genic upstream transcript variant, coding sequence variant
rs563582627	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, genic upstream transcript variant, intron variant
rs565784637	A>G	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, synonymous variant, coding sequence variant
rs566299753	G>T	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant
rs566794300	T>C	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, synonymous variant, intron variant, coding sequence variant
rs569003242	T>C	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, missense variant, intron variant
rs571348685	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic downstream transcript variant, missense variant
rs577363824	C>T	Pathogenic, uncertain-significance	Splice donor variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs577716745	C>T	Conflicting-interpretations-of-pathogenicity, likely-benign	Synonymous variant, coding sequence variant, genic upstream transcript variant
rs587780487	TTCAGGTAGAACTTCCTCTTCTTCAGGTAGAACTTCCTCTTC>-,TTCAGGTAGAACTTCCTCTTC	Conflicting-interpretations-of-pathogenicity, benign, likely-benign	Inframe deletion, genic downstream transcript variant, intron variant, genic upstream transcript variant, coding sequence variant
rs587780488	C>G,T	Pathogenic, conflicting-interpretations-of-pathogenicity, likely-benign, uncertain-significance	Missense variant, genic downstream transcript variant, coding sequence variant
rs587780987	G>A	Benign, conflicting-interpretations-of-pathogenicity	Synonymous variant, coding sequence variant, genic upstream transcript variant
rs727503636	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Splice donor variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs727503644	->A	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic downstream transcript variant, intron variant, genic upstream transcript variant
rs727503652	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant
rs727503655	T>C	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant, missense variant, genic upstream transcript variant, coding sequence variant
rs727503658	A>-	Likely-pathogenic, uncertain-significance	Genic downstream transcript variant, intron variant, genic upstream transcript variant, frameshift variant, coding sequence variant
rs727503661	G>A,T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic downstream transcript variant, intron variant, missense variant, genic upstream transcript variant, coding sequence variant
rs727503682	C>T	Conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant, genic upstream transcript variant
rs727504198	C>A,T	Conflicting-interpretations-of-pathogenicity, likely-pathogenic, uncertain-significance	Stop gained, genic downstream transcript variant, coding sequence variant, missense variant
rs727504199	TTC>-	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Inframe deletion, genic downstream transcript variant, coding sequence variant
rs727504452	CTGCCGTGCT>-	Likely-pathogenic	Genic downstream transcript variant, intron variant, genic upstream transcript variant, frameshift variant, coding sequence variant
rs727504499	G>A	Likely-pathogenic, uncertain-significance	Stop gained, genic downstream transcript variant, coding sequence variant
rs727504515	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic downstream transcript variant, intron variant, missense variant, genic upstream transcript variant, coding sequence variant
rs727504843	C>A	Likely-pathogenic	Genic downstream transcript variant, intron variant, genic upstream transcript variant, stop gained, coding sequence variant
rs727505256	T>C	Conflicting-interpretations-of-pathogenicity, likely-benign	Missense variant, coding sequence variant, genic upstream transcript variant
rs727505350	G>A	Conflicting-interpretations-of-pathogenicity, likely-pathogenic, uncertain-significance	Stop gained, genic downstream transcript variant, coding sequence variant
rs730880244	T>C,G	Likely-pathogenic, uncertain-significance	Genic downstream transcript variant, splice acceptor variant
rs746033038	C>A	Conflicting-interpretations-of-pathogenicity	Synonymous variant, coding sequence variant, genic upstream transcript variant
rs746115846	G>A	Likely-pathogenic	Stop gained, coding sequence variant, genic upstream transcript variant
rs746563654	T>C	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant, genic upstream transcript variant
rs746721983	G>A	Pathogenic, likely-pathogenic, uncertain-significance	Genic downstream transcript variant, intron variant, genic upstream transcript variant, stop gained, coding sequence variant
rs746912694	G>A,T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic downstream transcript variant, intron variant, genic upstream transcript variant, synonymous variant, coding sequence variant
rs747240394	G>T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic downstream transcript variant, intron variant, missense variant, genic upstream transcript variant, coding sequence variant
rs747286444	G>A,C	Likely-pathogenic, uncertain-significance	Intron variant, genic upstream transcript variant, missense variant, stop gained, coding sequence variant
rs747289468	G>A,C	Likely-pathogenic	Genic downstream transcript variant, intron variant, genic upstream transcript variant, missense variant, stop gained, coding sequence variant
rs747376234	G>C	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant, missense variant, genic upstream transcript variant, coding sequence variant
rs748313513	G>A,T	Likely-pathogenic	Stop gained, synonymous variant, coding sequence variant, genic upstream transcript variant
rs748675191	G>A,C	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant, genic upstream transcript variant
rs748885610	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant
rs749705939	C>T	Not-provided, pathogenic, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, splice acceptor variant
rs749823104	T>A,C	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant
rs749875409	G>C	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, missense variant, genic upstream transcript variant, intron variant
rs750996600	C>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant
rs751733811	G>A,T	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, missense variant, intron variant, synonymous variant
rs751902051	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant
rs752620885	G>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant
rs752856716	->A	Uncertain-significance, likely-pathogenic	Genic downstream transcript variant, frameshift variant, coding sequence variant
rs753356474	G>A,C	Uncertain-significance, likely-benign, conflicting-interpretations-of-pathogenicity	Synonymous variant, genic upstream transcript variant, coding sequence variant
rs753892271	C>A,T	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, missense variant, genic upstream transcript variant, intron variant
rs755492644	T>C	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, synonymous variant
rs755793186	A>G	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, synonymous variant, intron variant
rs756282138	A>G	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, synonymous variant
rs756475184	C>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, intron variant
rs756518824	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, synonymous variant, intron variant
rs757569345	C>T	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, synonymous variant
rs757604614	A>G	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, synonymous variant
rs758598014	G>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, synonymous variant
rs760666570	G>A,C	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, missense variant, coding sequence variant, synonymous variant
rs761859812	G>A,C	Likely-benign, conflicting-interpretations-of-pathogenicity	Synonymous variant, coding sequence variant, genic upstream transcript variant
rs762141482	A>G	Benign, conflicting-interpretations-of-pathogenicity	Intron variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant, synonymous variant
rs762330685	C>T	Conflicting-interpretations-of-pathogenicity	Intron variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant, synonymous variant
rs762470432	C>T	Likely-benign, conflicting-interpretations-of-pathogenicity	Synonymous variant, coding sequence variant, genic downstream transcript variant
rs763098227	TCT>-	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Intron variant, inframe deletion, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant
rs763361422	G>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, intron variant
rs763629416	C>A	Conflicting-interpretations-of-pathogenicity	Intron variant, coding sequence variant, genic downstream transcript variant, genic upstream transcript variant, synonymous variant
rs765019023	->A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, splice donor variant
rs765214404	C>T	Conflicting-interpretations-of-pathogenicity	Synonymous variant, coding sequence variant, genic downstream transcript variant
rs765647346	C>G	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant
rs767120669	C>A,T	Likely-pathogenic	Missense variant, stop gained, genic downstream transcript variant, coding sequence variant, intron variant
rs767137418	C>T	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant
rs767983460	G>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, synonymous variant
rs768632287	G>A	Conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs768936623	C>A,T	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant
rs769097909	C>A,T	Pathogenic, uncertain-significance	Missense variant, stop gained, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs769505705	G>A	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant
rs770029258	T>A,C	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, missense variant, stop gained
rs770084292	G>A	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant
rs770767998	G>A,C,T	Likely-pathogenic, uncertain-significance	Missense variant, stop gained, genic downstream transcript variant, coding sequence variant, synonymous variant
rs771562210	C>A,T	Likely-pathogenic, uncertain-significance	Genic downstream transcript variant, splice donor variant
rs771843862	C>G,T	Conflicting-interpretations-of-pathogenicity	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs771898264	TTC>-	Conflicting-interpretations-of-pathogenicity, likely-benign, uncertain-significance	Inframe deletion, genic upstream transcript variant, coding sequence variant
rs772195716	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs772235481	G>A,C	Pathogenic, uncertain-significance	Missense variant, stop gained, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs772600691	C>T	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant
rs772882862	T>A	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Missense variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant, intron variant
rs773744166	C>G	Conflicting-interpretations-of-pathogenicity	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant
rs775552018	C>T	Conflicting-interpretations-of-pathogenicity	Missense variant, intron variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant
rs775889693	G>A	Conflicting-interpretations-of-pathogenicity, benign	Synonymous variant, coding sequence variant, genic downstream transcript variant
rs775954427	T>C	Uncertain-significance, conflicting-interpretations-of-pathogenicity, likely-benign	Synonymous variant, coding sequence variant, genic downstream transcript variant
rs776361113	A>T	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant, intron variant, genic upstream transcript variant
rs777924443	CTCT>-	Pathogenic	Intron variant, genic downstream transcript variant, coding sequence variant, frameshift variant, genic upstream transcript variant
rs778172350	->C	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Frameshift variant, coding sequence variant, intron variant, genic upstream transcript variant
rs778338717	C>T	Conflicting-interpretations-of-pathogenicity	Synonymous variant, intron variant, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant
rs779549899	AG>-	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, intron variant, frameshift variant, genic downstream transcript variant
rs779652311	A>T	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, intron variant, missense variant, genic downstream transcript variant
rs780415493	G>A,C	Likely-pathogenic, uncertain-significance	Coding sequence variant, genic upstream transcript variant, stop gained, missense variant
rs781552736	G>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, intron variant, genic downstream transcript variant, synonymous variant
rs786205542	G>C	Likely-pathogenic	Coding sequence variant, missense variant, genic downstream transcript variant
rs786205543	T>C	Likely-pathogenic	Genic downstream transcript variant, genic upstream transcript variant, intron variant
rs786205544	T>C	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, intron variant, missense variant, genic downstream transcript variant
rs794727043	C>T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic downstream transcript variant, genic upstream transcript variant, splice donor variant, intron variant
rs794727178	A>G	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, synonymous variant
rs794727888	AA>-	Pathogenic	Genic upstream transcript variant, coding sequence variant, stop gained, intron variant, genic downstream transcript variant
rs794729311	GTAGTT>A	Likely-pathogenic	Frameshift variant, coding sequence variant, genic upstream transcript variant, intron variant
rs794729390	->GAGCT	Likely-pathogenic, pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs796314079	C>A	Likely-pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs797046060	GC>T	Pathogenic	Genic upstream transcript variant, coding sequence variant, intron variant, frameshift variant, genic downstream transcript variant
rs797046064	CAAA>-	Pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs866407525	T>C	Conflicting-interpretations-of-pathogenicity, likely-benign	Genic upstream transcript variant, coding sequence variant, intron variant, genic downstream transcript variant, synonymous variant
rs869025556	->T	Likely-pathogenic, uncertain-significance	Genic upstream transcript variant, coding sequence variant, intron variant, frameshift variant, genic downstream transcript variant
rs869238992	T>A	Likely-pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs869312037	CA>-	Likely-pathogenic	Frameshift variant, coding sequence variant, genic upstream transcript variant
rs869312038	TG>-	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, intron variant, frameshift variant, genic downstream transcript variant
rs869312039	G>A	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, stop gained, intron variant, genic downstream transcript variant
rs869312040	C>-	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, intron variant, frameshift variant, genic downstream transcript variant
rs869312041	C>-	Likely-pathogenic	Splice acceptor variant, genic downstream transcript variant, genic upstream transcript variant, intron variant
rs869312042	C>-	Likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs869312043	G>A	Likely-pathogenic, uncertain-significance	Coding sequence variant, stop gained, genic downstream transcript variant
rs869312044	C>-	Likely-pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs869312045	->T	Likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs869312046	A>C	Likely-pathogenic	Coding sequence variant, stop gained, genic downstream transcript variant
rs869312099	C>T	Pathogenic, uncertain-significance	Splice acceptor variant, genic downstream transcript variant, genic upstream transcript variant
rs869312102	C>T	Likely-pathogenic, uncertain-significance	Genic upstream transcript variant, coding sequence variant, stop gained, intron variant, genic downstream transcript variant
rs869312103	C>A	Likely-pathogenic, uncertain-significance	Genic upstream transcript variant, coding sequence variant, stop gained, intron variant, genic downstream transcript variant
rs869312104	T>-	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, intron variant, frameshift variant, genic downstream transcript variant
rs869312105	A>C,G	Likely-pathogenic	Coding sequence variant, stop gained, synonymous variant, genic downstream transcript variant
rs869312106	T>-	Likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs876657663	CGTGTAA>-	Likely-pathogenic	Frameshift variant, coding sequence variant, genic upstream transcript variant
rs876657664	G>-	Likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs876657673	->A	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, stop gained, intron variant, genic downstream transcript variant
rs878854299	C>A,T	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, coding sequence variant, stop gained, intron variant, missense variant, genic downstream transcript variant
rs878854369	C>G	Likely-pathogenic	Genic downstream transcript variant, splice donor variant
rs878854370	T>C	Likely-pathogenic	Genic downstream transcript variant, intron variant
rs878854371	TTTC>-	Likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs878903172	T>C	Conflicting-interpretations-of-pathogenicity, uncertain-significance	Genic upstream transcript variant, coding sequence variant, intron variant, genic downstream transcript variant, synonymous variant
rs878915517	G>A	Conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, coding sequence variant, intron variant, genic downstream transcript variant, synonymous variant
rs879103814	T>C	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, synonymous variant
rs886037909	A>G	Likely-pathogenic	Coding sequence variant, genic upstream transcript variant, missense variant
rs886042283	A>G	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant
rs886042511	T>C	Conflicting-interpretations-of-pathogenicity	Synonymous variant, coding sequence variant, genic downstream transcript variant
rs886042543	A>C	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant
rs886042667	C>T	Conflicting-interpretations-of-pathogenicity	Synonymous variant, coding sequence variant, genic downstream transcript variant
rs886044076	G>A	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, intron variant, synonymous variant, genic downstream transcript variant
rs886044306	A>G	Conflicting-interpretations-of-pathogenicity	Coding sequence variant, genic upstream transcript variant, intron variant, missense variant, genic downstream transcript variant
rs901197333	C>T	Conflicting-interpretations-of-pathogenicity	Intron variant, coding sequence variant, genic upstream transcript variant, genic downstream transcript variant, missense variant
rs1025136671	T>C	Likely-benign, conflicting-interpretations-of-pathogenicity	Genic upstream transcript variant, genic downstream transcript variant, intron variant
rs1029227575	T>A	Conflicting-interpretations-of-pathogenicity	Genic downstream transcript variant, intron variant, genic upstream transcript variant
rs1057518065	T>-	Likely-pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1057519160	C>T	Likely-pathogenic	Intron variant, genic downstream transcript variant, genic upstream transcript variant, coding sequence variant, stop gained
rs1057519237	G>A,C	Likely-pathogenic	Intron variant, genic downstream transcript variant, genic upstream transcript variant, missense variant, coding sequence variant, stop gained
rs1060500405	G>A	Likely-pathogenic, uncertain-significance	Coding sequence variant, stop gained, genic downstream transcript variant
rs1060500549	C>G	Uncertain-significance, pathogenic	Splice donor variant, genic upstream transcript variant
rs1060503946	T>A	Likely-benign, conflicting-interpretations-of-pathogenicity	Intron variant, genic downstream transcript variant, genic upstream transcript variant, synonymous variant, coding sequence variant
rs1114167333	CA>-	Likely-pathogenic	Coding sequence variant, frameshift variant, genic downstream transcript variant
rs1198364572	->T	Likely-pathogenic	Genic upstream transcript variant, frameshift variant, coding sequence variant, intron variant, genic downstream transcript variant
rs1198504900	T>C	Conflicting-interpretations-of-pathogenicity	Synonymous variant, genic upstream transcript variant, coding sequence variant, intron variant, genic downstream transcript variant
rs1228771607	A>G,T	Conflicting-interpretations-of-pathogenicity	Missense variant, coding sequence variant, synonymous variant, genic upstream transcript variant, genic downstream transcript variant, intron variant
rs1266489077	T>-	Likely-pathogenic	Coding sequence variant, genic downstream transcript variant, frameshift variant, genic upstream transcript variant, intron variant
rs1353528319	C>T	Likely-pathogenic	Splice donor variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs1389908421	C>T	Likely-pathogenic	Splice donor variant, genic downstream transcript variant, genic upstream transcript variant, intron variant
rs1408345511	G>-	Likely-pathogenic	Frameshift variant, genic upstream transcript variant, genic downstream transcript variant, coding sequence variant, intron variant
rs1454950897	->T	Likely-pathogenic	Coding sequence variant, intron variant, frameshift variant, genic upstream transcript variant
rs1553741321	->T	Likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553741531	C>A	Likely-pathogenic	Splice donor variant, genic downstream transcript variant
rs1553742630	->C	Uncertain-significance, likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553754743	->T	Likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant
rs1553775212	TTTCT>-	Likely-pathogenic	Frameshift variant, intron variant, coding sequence variant, genic downstream transcript variant
rs1553809971	G>-	Likely-pathogenic	Genic downstream transcript variant, frameshift variant, genic upstream transcript variant, intron variant, coding sequence variant
rs1553852989	C>A	Likely-pathogenic	Splice donor variant, intron variant, genic upstream transcript variant, genic downstream transcript variant
rs1553882262	AG>-	Pathogenic	Genic downstream transcript variant, frameshift variant, genic upstream transcript variant, intron variant, coding sequence variant
rs1553908254	G>C	Likely-pathogenic	Stop gained, genic downstream transcript variant, genic upstream transcript variant, intron variant, coding sequence variant
rs1553909995	TA>-	Likely-pathogenic	Genic downstream transcript variant, frameshift variant, genic upstream transcript variant, intron variant, coding sequence variant
rs1553915256	C>T	Pathogenic	Splice donor variant, intron variant, genic upstream transcript variant, genic downstream transcript variant
rs1553939749	GGGAGATGGTT>-	Likely-pathogenic	Genic downstream transcript variant, frameshift variant, genic upstream transcript variant, intron variant, coding sequence variant
rs1554015228	C>T	Likely-pathogenic	Genic upstream transcript variant, coding sequence variant, missense variant
rs1554023044	T>A	Likely-pathogenic	Genic upstream transcript variant, stop gained, coding sequence variant
rs1554042042	G>A	Likely-pathogenic	Genic upstream transcript variant, stop gained, coding sequence variant
rs1559873786	GATGTAT>-	Likely-pathogenic	Coding sequence variant, genic downstream transcript variant, frameshift variant
rs1559877046	T>A,C	Likely-pathogenic, uncertain-significance	Coding sequence variant, missense variant, genic downstream transcript variant, stop gained
rs1560513651	C>G	Pathogenic	Splice acceptor variant, genic upstream transcript variant, genic downstream transcript variant, intron variant
rs1560689563	A>G	Likely-pathogenic	Coding sequence variant, intron variant, genic downstream transcript variant, genic upstream transcript variant, missense variant
rs1561445221	T>-	Likely-pathogenic	Coding sequence variant, frameshift variant, genic upstream transcript variant
rs1574066113	C>-	Likely-pathogenic	Coding sequence variant, genic upstream transcript variant, genic downstream transcript variant, frameshift variant, intron variant
rs1574083547	GT>-	Likely-pathogenic	Coding sequence variant, genic upstream transcript variant, genic downstream transcript variant, frameshift variant, intron variant
rs1574087037	G>A	Likely-pathogenic	Coding sequence variant, stop gained, genic upstream transcript variant, genic downstream transcript variant, intron variant
rs1574570125	G>C	Likely-pathogenic	Coding sequence variant, genic upstream transcript variant, stop gained
rs1574817395	A>G	Pathogenic	Splice donor variant, genic upstream transcript variant
rs1574982376	C>T	Pathogenic	Splice donor variant, genic upstream transcript variant
rs1574990483	->A	Likely-pathogenic	Frameshift variant, coding sequence variant, genic upstream transcript variant
rs1576608220	CA>-	Likely-pathogenic	Frameshift variant, genic downstream transcript variant, coding sequence variant
rs1576685753	->AGGC	Likely-pathogenic	Frameshift variant, genic downstream transcript variant, coding sequence variant
rs1576742510	C>A	Likely-pathogenic	Stop gained, genic downstream transcript variant, coding sequence variant
rs1577134819	T>C	Likely-pathogenic	Splice acceptor variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs1577824925	C>A	Likely-pathogenic	Splice donor variant, genic downstream transcript variant, intron variant, genic upstream transcript variant
rs1578126437	G>A	Pathogenic	Intron variant, stop gained, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant
rs1578175759	->AAAG	Likely-pathogenic	Intron variant, inframe indel, stop gained, genic downstream transcript variant, coding sequence variant, genic upstream transcript variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT050140	hsa-miR-26a-5p	CLASH	23622248
MIRT054851	hsa-miR-144-3p	Luciferase reporter assay, qRT-PCR, Western blot	24453045
MIRT1462509	hsa-miR-199a-3p	CLIP-seq
MIRT1462510	hsa-miR-199b-3p	CLIP-seq
MIRT1462511	hsa-miR-3129-5p	CLIP-seq
MIRT1462512	hsa-miR-331-5p	CLIP-seq
MIRT1462513	hsa-miR-3920	CLIP-seq
MIRT1462514	hsa-miR-4678	CLIP-seq
MIRT1462515	hsa-miR-4762-3p	CLIP-seq
MIRT1462516	hsa-miR-532-5p	CLIP-seq
MIRT1462517	hsa-miR-936	CLIP-seq
MIRT1462518	hsa-miR-3545-3p	CLIP-seq
MIRT1462519	hsa-miR-4729	CLIP-seq
MIRT2462647	hsa-miR-3133	CLIP-seq
MIRT2462648	hsa-miR-4511	CLIP-seq
MIRT2462649	hsa-miR-489	CLIP-seq
MIRT2462650	hsa-miR-499-3p	CLIP-seq
MIRT2462651	hsa-miR-499a-3p	CLIP-seq
MIRT2462652	hsa-miR-520g	CLIP-seq
MIRT2462653	hsa-miR-520h	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000166	Function	Nucleotide binding	IEA
GO:0000794	Component	Condensed nuclear chromosome	IDA	9548712
GO:0002020	Function	Protease binding	IPI	9642272
GO:0003009	Process	Skeletal muscle contraction	NAS	16407954
GO:0003300	Process	Cardiac muscle hypertrophy	IMP	11846417
GO:0004672	Function	Protein kinase activity	IEA
GO:0004674	Function	Protein serine/threonine kinase activity	IDA	9804419
GO:0004674	Function	Protein serine/threonine kinase activity	IEA
GO:0004713	Function	Protein tyrosine kinase activity	IDA	18765796
GO:0005198	Function	Structural molecule activity	IEA
GO:0005509	Function	Calcium ion binding	IDA	7607248
GO:0005515	Function	Protein binding	IPI	7607248, 9501083, 11101506, 11448995, 11717165, 11846417, 12482578, 14583192, 15582318, 16407954, 16902413, 16962094, 18157088, 19622741, 20133654, 20489725, 20562859, 20860623, 23414517, 25447537, 35044719
GO:0005516	Function	Calmodulin binding	IEA
GO:0005516	Function	Calmodulin binding	IPI	7607248
GO:0005516	Function	Calmodulin binding	TAS	10481174
GO:0005524	Function	ATP binding	IEA
GO:0005576	Component	Extracellular region	TAS
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005865	Component	Striated muscle thin filament	IDA	11717165
GO:0006936	Process	Muscle contraction	IEA
GO:0006936	Process	Muscle contraction	NAS	10481174
GO:0006936	Process	Muscle contraction	TAS	11911777
GO:0006941	Process	Striated muscle contraction	TAS	7569978
GO:0007076	Process	Mitotic chromosome condensation	IEP	9548712
GO:0008092	Function	Cytoskeletal protein binding	IEA
GO:0008307	Function	Structural constituent of muscle	IMP	9817758, 11846417
GO:0008307	Function	Structural constituent of muscle	TAS	7569978
GO:0010628	Process	Positive regulation of gene expression	IGI	25152160
GO:0010628	Process	Positive regulation of gene expression	IMP	25152160
GO:0010737	Process	Protein kinase A signaling	IMP	25152160
GO:0015629	Component	Actin cytoskeleton	IEA
GO:0016301	Function	Kinase activity	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0019887	Function	Protein kinase regulator activity	IMP	9804419
GO:0019899	Function	Enzyme binding	IPI	18310072
GO:0019901	Function	Protein kinase binding	IPI	23283722
GO:0030018	Component	Z disc	IDA	9501083, 9817758, 11717165, 19850579
GO:0030018	Component	Z disc	IEA
GO:0030049	Process	Muscle filament sliding	NAS	16407954
GO:0030240	Process	Skeletal muscle thin filament assembly	IMP	9817758
GO:0030241	Process	Skeletal muscle myosin thick filament assembly	IMP	9817758
GO:0031430	Component	M band	IBA
GO:0031430	Component	M band	IDA	11717165
GO:0031430	Component	M band	IEA
GO:0031433	Function	Telethonin binding	IPI	11846417, 15582318
GO:0031433	Function	Telethonin binding	ISS
GO:0031674	Component	I band	IDA	9817758
GO:0032991	Component	Protein-containing complex	IEA
GO:0035995	Process	Detection of muscle stretch	IDA	18765796
GO:0035995	Process	Detection of muscle stretch	TAS	12507422
GO:0042802	Function	Identical protein binding	IPI	9804419, 16407954, 16962974, 23414517
GO:0042803	Function	Protein homodimerization activity	IPI	9804419
GO:0042805	Function	Actinin binding	IDA	9501083
GO:0042805	Function	Actinin binding	IPI	11846417
GO:0045214	Process	Sarcomere organization	IBA
GO:0045214	Process	Sarcomere organization	IEA
GO:0045214	Process	Sarcomere organization	IMP	9804419, 9817758, 11846417
GO:0045214	Process	Sarcomere organization	NAS	16407954
GO:0046872	Function	Metal ion binding	IEA
GO:0048769	Process	Sarcomerogenesis	IMP	9817758
GO:0050714	Process	Positive regulation of protein secretion	IGI	25152160
GO:0050714	Process	Positive regulation of protein secretion	IMP	25152160
GO:0051015	Function	Actin filament binding	IDA	9501083
GO:0051371	Function	Muscle alpha-actinin binding	IPI	9501083
GO:0051592	Process	Response to calcium ion	IDA	7607248
GO:0055003	Process	Cardiac myofibril assembly	IEA
GO:0055003	Process	Cardiac myofibril assembly	IMP	9817758, 11846417
GO:0055003	Process	Cardiac myofibril assembly	NAS	16407954
GO:0055008	Process	Cardiac muscle tissue morphogenesis	IEA
GO:0055008	Process	Cardiac muscle tissue morphogenesis	IMP	9817758
GO:0055013	Process	Cardiac muscle cell development	IMP	9817758
GO:0060048	Process	Cardiac muscle contraction	IMP	11846417
GO:0060048	Process	Cardiac muscle contraction	NAS	16407954
GO:0070062	Component	Extracellular exosome	HDA	19056867
GO:0097493	Function	Structural molecule activity conferring elasticity	IDA	9804419
GO:0097493	Function	Structural molecule activity conferring elasticity	TAS	23283722
GO:0106310	Function	Protein serine kinase activity	IEA
GO:1990733	Component	Titin-telethonin complex	IPI	16407954

Other IDs

• MIM: 188840
• HGNC: 12403
• e!Ensembl: ENSG00000155657

Protein

• UniProt ID: Q8WZ42
• Protein name: Titin (EC 2.7.11.1) (Connectin) (Rhabdomyosarcoma antigen MU-RMS-40.14)
• Protein function: Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and
• PDB: 1BPV, 1G1C, 1NCT, 1NCU, 1TIT, 1TIU, 1TKI, 1TNM, 1TNN, 1WAA, 1YA5, 2A38, 2BK8, 2F8V, 2ILL, 2J8H, 2J8O, 2NZI, 2RQ8, 2WP3, 2WWK, 2WWM, 2Y9R, 3B43, 3KNB, 3LCY, 3LPW, 3PUC, 3Q5O, 3QP3, 4C4K, 4JNW, 4O00, 4QEG, 4UOW, 5BS0, 5JDD, 5JDE, 5JDJ, 5JOE, 6DL4, 6FWX, 6H4L, 6HCI, 6I0Y, 6SDB, 6YGN, 7AHS, 7NIP, 8BNQ, 8BVO
• Family and domains:

  Pfam

  
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  Accession	ID	Position in sequence	Description	Type
  PF07679	I-set	6 → 97	Immunoglobulin I-set domain	Domain
  PF07679	I-set	104 → 193	Immunoglobulin I-set domain	Domain
  PF09042	Titin_Z	383 → 454	Titin Z	Domain
  PF09042	Titin_Z	464 → 505	Titin Z	Domain
  PF09042	Titin_Z	510 → 549	Titin Z	Domain
  PF09042	Titin_Z	552 → 593	Titin Z	Domain
  PF09042	Titin_Z	598 → 639	Titin Z	Domain
  PF09042	Titin_Z	644 → 685	Titin Z	Domain
  PF09042	Titin_Z	696 → 728	Titin Z	Domain
  PF07679	I-set	943 → 1032	Immunoglobulin I-set domain	Domain
  PF07679	I-set	1082 → 1172	Immunoglobulin I-set domain	Domain
  PF07679	I-set	1291 → 1381	Immunoglobulin I-set domain	Domain
  PF07679	I-set	1457 → 1547	Immunoglobulin I-set domain	Domain
  PF07679	I-set	1556 → 1647	Immunoglobulin I-set domain	Domain
  PF07679	I-set	1703 → 1794	Immunoglobulin I-set domain	Domain
  PF07679	I-set	1841 → 1929	Immunoglobulin I-set domain	Domain
  PF07679	I-set	2078 → 2168	Immunoglobulin I-set domain	Domain
  PF07679	I-set	2174 → 2262	Immunoglobulin I-set domain	Domain
  PF07679	I-set	2267 → 2352	Immunoglobulin I-set domain	Domain
  PF07679	I-set	2356 → 2437	Immunoglobulin I-set domain	Domain
  PF07679	I-set	2445 → 2530	Immunoglobulin I-set domain	Domain
  PF07679	I-set	2533 → 2618	Immunoglobulin I-set domain	Domain
  PF07679	I-set	2621 → 2706	Immunoglobulin I-set domain	Domain
  PF07679	I-set	2707 → 2785	Immunoglobulin I-set domain	Domain
  PF07679	I-set	2795 → 2879	Immunoglobulin I-set domain	Domain
  PF07679	I-set	2882 → 2967	Immunoglobulin I-set domain	Domain
  PF07679	I-set	2969 → 3054	Immunoglobulin I-set domain	Domain
  PF07679	I-set	3058 → 3142	Immunoglobulin I-set domain	Domain
  PF07679	I-set	3147 → 3233	Immunoglobulin I-set domain	Domain
  PF07679	I-set	3239 → 3328	Immunoglobulin I-set domain	Domain
  PF07679	I-set	3345 → 3433	Immunoglobulin I-set domain	Domain
  PF07679	I-set	3503 → 3592	Immunoglobulin I-set domain	Domain
  PF07679	I-set	3621 → 3711	Immunoglobulin I-set domain	Domain
  PF07679	I-set	4289 → 4377	Immunoglobulin I-set domain	Domain
  PF07679	I-set	4383 → 4472	Immunoglobulin I-set domain	Domain
  PF07679	I-set	4478 → 4567	Immunoglobulin I-set domain	Domain
  PF07679	I-set	4571 → 4660	Immunoglobulin I-set domain	Domain
  PF07679	I-set	4664 → 4754	Immunoglobulin I-set domain	Domain
  PF07679	I-set	4758 → 4845	Immunoglobulin I-set domain	Domain
  PF07679	I-set	4851 → 4940	Immunoglobulin I-set domain	Domain
  PF07679	I-set	4944 → 5033	Immunoglobulin I-set domain	Domain
  PF07679	I-set	5040 → 5129	Immunoglobulin I-set domain	Domain
  PF07679	I-set	5133 → 5222	Immunoglobulin I-set domain	Domain
  PF07679	I-set	5226 → 5316	Immunoglobulin I-set domain	Domain
  PF07679	I-set	5320 → 5409	Immunoglobulin I-set domain	Domain
  PF07679	I-set	5413 → 5502	Immunoglobulin I-set domain	Domain
  PF07679	I-set	5506 → 5595	Immunoglobulin I-set domain	Domain
  PF07679	I-set	5602 → 5691	Immunoglobulin I-set domain	Domain
  PF07679	I-set	5695 → 5784	Immunoglobulin I-set domain	Domain
  PF07679	I-set	5788 → 5878	Immunoglobulin I-set domain	Domain
  PF07679	I-set	5882 → 5971	Immunoglobulin I-set domain	Domain
  PF07679	I-set	5975 → 6064	Immunoglobulin I-set domain	Domain
  PF07679	I-set	6068 → 6157	Immunoglobulin I-set domain	Domain
  PF07679	I-set	6164 → 6253	Immunoglobulin I-set domain	Domain
  PF07679	I-set	6257 → 6346	Immunoglobulin I-set domain	Domain
  PF07679	I-set	6350 → 6440	Immunoglobulin I-set domain	Domain
  PF07679	I-set	6444 → 6533	Immunoglobulin I-set domain	Domain
  PF07679	I-set	6537 → 6627	Immunoglobulin I-set domain	Domain
  PF07679	I-set	6631 → 6720	Immunoglobulin I-set domain	Domain
  PF07679	I-set	6727 → 6816	Immunoglobulin I-set domain	Domain
  PF07679	I-set	6820 → 6909	Immunoglobulin I-set domain	Domain
  PF07679	I-set	6913 → 7001	Immunoglobulin I-set domain	Domain
  PF07679	I-set	7006 → 7095	Immunoglobulin I-set domain	Domain
  PF07679	I-set	7102 → 7191	Immunoglobulin I-set domain	Domain
  PF07679	I-set	7198 → 7287	Immunoglobulin I-set domain	Domain
  PF07679	I-set	7291 → 7381	Immunoglobulin I-set domain	Domain
  PF07679	I-set	7385 → 7474	Immunoglobulin I-set domain	Domain
  PF07679	I-set	7478 → 7568	Immunoglobulin I-set domain	Domain
  PF07679	I-set	7572 → 7661	Immunoglobulin I-set domain	Domain
  PF07679	I-set	7668 → 7757	Immunoglobulin I-set domain	Domain
  PF07679	I-set	7761 → 7850	Immunoglobulin I-set domain	Domain
  PF07679	I-set	7854 → 7943	Immunoglobulin I-set domain	Domain
  PF07679	I-set	7947 → 8036	Immunoglobulin I-set domain	Domain
  PF07679	I-set	8043 → 8132	Immunoglobulin I-set domain	Domain
  PF07679	I-set	8139 → 8228	Immunoglobulin I-set domain	Domain
  PF07679	I-set	8232 → 8322	Immunoglobulin I-set domain	Domain
  PF07679	I-set	8326 → 8415	Immunoglobulin I-set domain	Domain
  PF07679	I-set	8419 → 8509	Immunoglobulin I-set domain	Domain
  PF07679	I-set	8513 → 8602	Immunoglobulin I-set domain	Domain
  PF07679	I-set	8609 → 8698	Immunoglobulin I-set domain	Domain
  PF07679	I-set	8702 → 8791	Immunoglobulin I-set domain	Domain
  PF07679	I-set	8795 → 8884	Immunoglobulin I-set domain	Domain
  PF07679	I-set	8888 → 8977	Immunoglobulin I-set domain	Domain
  PF07679	I-set	8984 → 9073	Immunoglobulin I-set domain	Domain
  PF07679	I-set	9080 → 9169	Immunoglobulin I-set domain	Domain
  PF07679	I-set	9176 → 9266	Immunoglobulin I-set domain	Domain
  PF07679	I-set	9273 → 9362	Immunoglobulin I-set domain	Domain
  PF07679	I-set	9381 → 9471	Immunoglobulin I-set domain	Domain
  PF18362	THB	9505 → 9537	Tri-helix bundle domain	Domain
  PF07679	I-set	9583 → 9669	Immunoglobulin I-set domain	Domain
  PF07679	I-set	9672 → 9757	Immunoglobulin I-set domain	Domain
  PF07679	I-set	9761 → 9850	Immunoglobulin I-set domain	Domain
  PF02818	PPAK	10503 → 10529	PPAK motif	Motif
  PF02818	PPAK	10587 → 10613	PPAK motif	Motif
  PF02818	PPAK	10615 → 10641	PPAK motif	Motif
  PF02818	PPAK	10927 → 10953	PPAK motif	Motif
  PF02818	PPAK	10955 → 10981	PPAK motif	Motif
  PF02818	PPAK	10983 → 11009	PPAK motif	Motif
  PF02818	PPAK	11698 → 11724	PPAK motif	Motif
  PF07679	I-set	12043 → 12134	Immunoglobulin I-set domain	Domain
  PF07679	I-set	12413 → 12497	Immunoglobulin I-set domain	Domain
  PF07679	I-set	12501 → 12585	Immunoglobulin I-set domain	Domain
  PF07679	I-set	12590 → 12675	Immunoglobulin I-set domain	Domain
  PF07679	I-set	12767 → 12850	Immunoglobulin I-set domain	Domain
  PF07679	I-set	12856 → 12941	Immunoglobulin I-set domain	Domain
  PF07679	I-set	12945 → 13027	Immunoglobulin I-set domain	Domain
  PF07679	I-set	13124 → 13204	Immunoglobulin I-set domain	Domain
  PF07679	I-set	13212 → 13295	Immunoglobulin I-set domain	Domain
  PF07679	I-set	13301 → 13382	Immunoglobulin I-set domain	Domain
  PF07679	I-set	13390 → 13475	Immunoglobulin I-set domain	Domain
  PF07679	I-set	13479 → 13563	Immunoglobulin I-set domain	Domain
  PF07679	I-set	13567 → 13656	Immunoglobulin I-set domain	Domain
  PF07679	I-set	13661 → 13745	Immunoglobulin I-set domain	Domain
  PF07679	I-set	13750 → 13832	Immunoglobulin I-set domain	Domain
  PF07679	I-set	13839 → 13924	Immunoglobulin I-set domain	Domain
  PF07679	I-set	13927 → 14013	Immunoglobulin I-set domain	Domain
  PF00041	fn3	14018 → 14103	Fibronectin type III domain	Domain
  PF00041	fn3	14119 → 14204	Fibronectin type III domain	Domain
  PF00041	fn3	14220 → 14305	Fibronectin type III domain	Domain
  PF07679	I-set	14327 → 14411	Immunoglobulin I-set domain	Domain
  PF00041	fn3	14416 → 14500	Fibronectin type III domain	Domain
  PF00041	fn3	14516 → 14600	Fibronectin type III domain	Domain
  PF07679	I-set	14621 → 14707	Immunoglobulin I-set domain	Domain
  PF00041	fn3	14712 → 14795	Fibronectin type III domain	Domain
  PF00041	fn3	14811 → 14896	Fibronectin type III domain	Domain
  PF00041	fn3	14912 → 14996	Fibronectin type III domain	Domain
  PF00041	fn3	15012 → 15096	Fibronectin type III domain	Domain
  PF00041	fn3	15112 → 15197	Fibronectin type III domain	Domain
  PF00041	fn3	15213 → 15299	Fibronectin type III domain	Domain
  PF07679	I-set	15314 → 15403	Immunoglobulin I-set domain	Domain
  PF00041	fn3	15407 → 15491	Fibronectin type III domain	Domain
  PF00041	fn3	15508 → 15593	Fibronectin type III domain	Domain
  PF07679	I-set	15610 → 15725	Immunoglobulin I-set domain	Domain
  PF00041	fn3	15730 → 15815	Fibronectin type III domain	Domain
  PF00041	fn3	15831 → 15915	Fibronectin type III domain	Domain
  PF00041	fn3	15930 → 16015	Fibronectin type III domain	Domain
  PF07679	I-set	16036 → 16120	Immunoglobulin I-set domain	Domain
  PF00041	fn3	16125 → 16208	Fibronectin type III domain	Domain
  PF00041	fn3	16223 → 16308	Fibronectin type III domain	Domain
  PF07679	I-set	16327 → 16421	Immunoglobulin I-set domain	Domain
  PF00041	fn3	16426 → 16511	Fibronectin type III domain	Domain
  PF00041	fn3	16527 → 16617	Fibronectin type III domain	Domain
  PF00041	fn3	16633 → 16720	Fibronectin type III domain	Domain
  PF07679	I-set	16741 → 16835	Immunoglobulin I-set domain	Domain
  PF00041	fn3	16840 → 16924	Fibronectin type III domain	Domain
  PF00041	fn3	16940 → 17030	Fibronectin type III domain	Domain
  PF07679	I-set	17047 → 17140	Immunoglobulin I-set domain	Domain
  PF00041	fn3	17146 → 17229	Fibronectin type III domain	Domain
  PF00041	fn3	17245 → 17334	Fibronectin type III domain	Domain
  PF00041	fn3	17349 → 17434	Fibronectin type III domain	Domain
  PF07679	I-set	17454 → 17539	Immunoglobulin I-set domain	Domain
  PF00041	fn3	17545 → 17628	Fibronectin type III domain	Domain
  PF00041	fn3	17645 → 17730	Fibronectin type III domain	Domain
  PF07679	I-set	17750 → 17835	Immunoglobulin I-set domain	Domain
  PF00041	fn3	17841 → 17924	Fibronectin type III domain	Domain
  PF00041	fn3	17940 → 18025	Fibronectin type III domain	Domain
  PF00041	fn3	18041 → 18128	Fibronectin type III domain	Domain
  PF07679	I-set	18149 → 18233	Immunoglobulin I-set domain	Domain
  PF00041	fn3	18238 → 18321	Fibronectin type III domain	Domain
  PF00041	fn3	18338 → 18421	Fibronectin type III domain	Domain
  PF07679	I-set	18439 → 18527	Immunoglobulin I-set domain	Domain
  PF00041	fn3	18532 → 18616	Fibronectin type III domain	Domain
  PF00041	fn3	18632 → 18716	Fibronectin type III domain	Domain
  PF00041	fn3	18732 → 18818	Fibronectin type III domain	Domain
  PF07679	I-set	18838 → 18925	Immunoglobulin I-set domain	Domain
  PF00041	fn3	18929 → 19013	Fibronectin type III domain	Domain
  PF00041	fn3	19029 → 19113	Fibronectin type III domain	Domain
  PF07679	I-set	19128 → 19220	Immunoglobulin I-set domain	Domain
  PF00041	fn3	19225 → 19309	Fibronectin type III domain	Domain
  PF00041	fn3	19324 → 19409	Fibronectin type III domain	Domain
  PF00041	fn3	19425 → 19516	Fibronectin type III domain	Domain
  PF07679	I-set	19536 → 19622	Immunoglobulin I-set domain	Domain
  PF00041	fn3	19627 → 19711	Fibronectin type III domain	Domain
  PF00041	fn3	19727 → 19812	Fibronectin type III domain	Domain
  PF07679	I-set	19828 → 19915	Immunoglobulin I-set domain	Domain
  PF00041	fn3	19920 → 20004	Fibronectin type III domain	Domain
  PF00041	fn3	20020 → 20105	Fibronectin type III domain	Domain
  PF00041	fn3	20118 → 20205	Fibronectin type III domain	Domain
  PF07679	I-set	20225 → 20312	Immunoglobulin I-set domain	Domain
  PF00041	fn3	20317 → 20400	Fibronectin type III domain	Domain
  PF00041	fn3	20418 → 20501	Fibronectin type III domain	Domain
  PF00041	fn3	20517 → 20603	Fibronectin type III domain	Domain
  PF07679	I-set	20624 → 20710	Immunoglobulin I-set domain	Domain
  PF00041	fn3	20715 → 20799	Fibronectin type III domain	Domain
  PF00041	fn3	20812 → 20894	Fibronectin type III domain	Domain
  PF07679	I-set	20919 → 20999	Immunoglobulin I-set domain	Domain
  PF00041	fn3	21006 → 21089	Fibronectin type III domain	Domain
  PF00041	fn3	21104 → 21189	Fibronectin type III domain	Domain
  PF00041	fn3	21202 → 21288	Fibronectin type III domain	Domain
  PF07679	I-set	21309 → 21396	Immunoglobulin I-set domain	Domain
  PF00041	fn3	21401 → 21485	Fibronectin type III domain	Domain
  PF00041	fn3	21500 → 21585	Fibronectin type III domain	Domain
  PF00041	fn3	21601 → 21687	Fibronectin type III domain	Domain
  PF07679	I-set	21704 → 21791	Immunoglobulin I-set domain	Domain
  PF00041	fn3	21796 → 21880	Fibronectin type III domain	Domain
  PF00041	fn3	21893 → 21976	Fibronectin type III domain	Domain
  PF07679	I-set	21996 → 22082	Immunoglobulin I-set domain	Domain
  PF00041	fn3	22087 → 22171	Fibronectin type III domain	Domain
  PF00041	fn3	22187 → 22272	Fibronectin type III domain	Domain
  PF00041	fn3	22285 → 22371	Fibronectin type III domain	Domain
  PF07679	I-set	22388 → 22478	Immunoglobulin I-set domain	Domain
  PF00041	fn3	22483 → 22568	Fibronectin type III domain	Domain
  PF00041	fn3	22583 → 22668	Fibronectin type III domain	Domain
  PF00041	fn3	22684 → 22770	Fibronectin type III domain	Domain
  PF07679	I-set	22790 → 22875	Immunoglobulin I-set domain	Domain
  PF00041	fn3	22880 → 22964	Fibronectin type III domain	Domain
  PF00041	fn3	22977 → 23060	Fibronectin type III domain	Domain
  PF07679	I-set	23075 → 23164	Immunoglobulin I-set domain	Domain
  PF00041	fn3	23169 → 23253	Fibronectin type III domain	Domain
  PF00041	fn3	23269 → 23354	Fibronectin type III domain	Domain
  PF00041	fn3	23367 → 23453	Fibronectin type III domain	Domain
  PF07679	I-set	23470 → 23560	Immunoglobulin I-set domain	Domain
  PF00041	fn3	23565 → 23650	Fibronectin type III domain	Domain
  PF00041	fn3	23665 → 23750	Fibronectin type III domain	Domain
  PF00041	fn3	23766 → 23852	Fibronectin type III domain	Domain
  PF07679	I-set	23873 → 23957	Immunoglobulin I-set domain	Domain
  PF00041	fn3	23962 → 24046	Fibronectin type III domain	Domain
  PF00041	fn3	24059 → 24143	Fibronectin type III domain	Domain
  PF07679	I-set	24157 → 24245	Immunoglobulin I-set domain	Domain
  PF00041	fn3	24251 → 24335	Fibronectin type III domain	Domain
  PF00041	fn3	24351 → 24436	Fibronectin type III domain	Domain
  PF00041	fn3	24449 → 24535	Fibronectin type III domain	Domain
  PF07679	I-set	24552 → 24642	Immunoglobulin I-set domain	Domain
  PF00041	fn3	24647 → 24732	Fibronectin type III domain	Domain
  PF00041	fn3	24747 → 24832	Fibronectin type III domain	Domain
  PF00041	fn3	24848 → 24934	Fibronectin type III domain	Domain
  PF07679	I-set	24953 → 25039	Immunoglobulin I-set domain	Domain
  PF00041	fn3	25044 → 25127	Fibronectin type III domain	Domain
  PF00041	fn3	25141 → 25224	Fibronectin type III domain	Domain
  PF07679	I-set	25239 → 25328	Immunoglobulin I-set domain	Domain
  PF00041	fn3	25334 → 25417	Fibronectin type III domain	Domain
  PF00041	fn3	25433 → 25518	Fibronectin type III domain	Domain
  PF00041	fn3	25531 → 25617	Fibronectin type III domain	Domain
  PF07679	I-set	25637 → 25725	Immunoglobulin I-set domain	Domain
  PF00041	fn3	25730 → 25815	Fibronectin type III domain	Domain
  PF00041	fn3	25830 → 25915	Fibronectin type III domain	Domain
  PF00041	fn3	25931 → 26017	Fibronectin type III domain	Domain
  PF07679	I-set	26035 → 26122	Immunoglobulin I-set domain	Domain
  PF00041	fn3	26127 → 26211	Fibronectin type III domain	Domain
  PF00041	fn3	26224 → 26307	Fibronectin type III domain	Domain
  PF07679	I-set	26322 → 26411	Immunoglobulin I-set domain	Domain
  PF00041	fn3	26416 → 26500	Fibronectin type III domain	Domain
  PF00041	fn3	26515 → 26600	Fibronectin type III domain	Domain
  PF00041	fn3	26613 → 26699	Fibronectin type III domain	Domain
  PF07679	I-set	26717 → 26806	Immunoglobulin I-set domain	Domain
  PF00041	fn3	26811 → 26896	Fibronectin type III domain	Domain
  PF00041	fn3	26911 → 26996	Fibronectin type III domain	Domain
  PF00041	fn3	27012 → 27096	Fibronectin type III domain	Domain
  PF07679	I-set	27114 → 27201	Immunoglobulin I-set domain	Domain
  PF00041	fn3	27206 → 27290	Fibronectin type III domain	Domain
  PF00041	fn3	27303 → 27386	Fibronectin type III domain	Domain
  PF07679	I-set	27404 → 27493	Immunoglobulin I-set domain	Domain
  PF00041	fn3	27498 → 27582	Fibronectin type III domain	Domain
  PF00041	fn3	27598 → 27683	Fibronectin type III domain	Domain
  PF00041	fn3	27696 → 27782	Fibronectin type III domain	Domain
  PF07679	I-set	27803 → 27889	Immunoglobulin I-set domain	Domain
  PF00041	fn3	27894 → 27979	Fibronectin type III domain	Domain
  PF00041	fn3	27994 → 28079	Fibronectin type III domain	Domain
  PF00041	fn3	28095 → 28181	Fibronectin type III domain	Domain
  PF07679	I-set	28201 → 28289	Immunoglobulin I-set domain	Domain
  PF00041	fn3	28294 → 28377	Fibronectin type III domain	Domain
  PF00041	fn3	28390 → 28473	Fibronectin type III domain	Domain
  PF07679	I-set	28491 → 28578	Immunoglobulin I-set domain	Domain
  PF00041	fn3	28585 → 28669	Fibronectin type III domain	Domain
  PF00041	fn3	28685 → 28770	Fibronectin type III domain	Domain
  PF00041	fn3	28783 → 28868	Fibronectin type III domain	Domain
  PF07679	I-set	28891 → 28975	Immunoglobulin I-set domain	Domain
  PF00041	fn3	28981 → 29064	Fibronectin type III domain	Domain
  PF00041	fn3	29080 → 29166	Fibronectin type III domain	Domain
  PF00041	fn3	29182 → 29266	Fibronectin type III domain	Domain
  PF07679	I-set	29286 → 29372	Immunoglobulin I-set domain	Domain
  PF00041	fn3	29377 → 29461	Fibronectin type III domain	Domain
  PF00041	fn3	29474 → 29557	Fibronectin type III domain	Domain
  PF07679	I-set	29577 → 29664	Immunoglobulin I-set domain	Domain
  PF00041	fn3	29670 → 29753	Fibronectin type III domain	Domain
  PF00041	fn3	29769 → 29854	Fibronectin type III domain	Domain
  PF00041	fn3	29867 → 29956	Fibronectin type III domain	Domain
  PF07679	I-set	29980 → 30064	Immunoglobulin I-set domain	Domain
  PF00041	fn3	30068 → 30152	Fibronectin type III domain	Domain
  PF00041	fn3	30168 → 30254	Fibronectin type III domain	Domain
  PF00041	fn3	30270 → 30356	Fibronectin type III domain	Domain
  PF07679	I-set	30376 → 30461	Immunoglobulin I-set domain	Domain
  PF00041	fn3	30466 → 30549	Fibronectin type III domain	Domain
  PF00041	fn3	30563 → 30648	Fibronectin type III domain	Domain
  PF07679	I-set	30666 → 30755	Immunoglobulin I-set domain	Domain
  PF00041	fn3	30760 → 30844	Fibronectin type III domain	Domain
  PF00041	fn3	30860 → 30945	Fibronectin type III domain	Domain
  PF00041	fn3	30961 → 31046	Fibronectin type III domain	Domain
  PF07679	I-set	31067 → 31151	Immunoglobulin I-set domain	Domain
  PF00041	fn3	31157 → 31240	Fibronectin type III domain	Domain
  PF00041	fn3	31257 → 31343	Fibronectin type III domain	Domain
  PF00041	fn3	31359 → 31444	Fibronectin type III domain	Domain
  PF07679	I-set	31460 → 31549	Immunoglobulin I-set domain	Domain
  PF07679	I-set	31562 → 31646	Immunoglobulin I-set domain	Domain
  PF00041	fn3	31651 → 31736	Fibronectin type III domain	Domain
  PF00041	fn3	31753 → 31838	Fibronectin type III domain	Domain
  PF07679	I-set	31855 → 31946	Immunoglobulin I-set domain	Domain
  PF07679	I-set	31955 → 32045	Immunoglobulin I-set domain	Domain
  PF00041	fn3	32050 → 32133	Fibronectin type III domain	Domain
  PF00069	Pkinase	32178 → 32432	Protein kinase domain	Domain
  PF07679	I-set	32496 → 32585	Immunoglobulin I-set domain	Domain
  PF07679	I-set	32617 → 32709	Immunoglobulin I-set domain	Domain
  PF07679	I-set	32722 → 32812	Immunoglobulin I-set domain	Domain
  PF07679	I-set	33301 → 33390	Immunoglobulin I-set domain	Domain
  PF07679	I-set	33488 → 33577	Immunoglobulin I-set domain	Domain
  PF07679	I-set	33645 → 33734	Immunoglobulin I-set domain	Domain
  PF07679	I-set	33779 → 33868	Immunoglobulin I-set domain	Domain
  PF07679	I-set	33966 → 34053	Immunoglobulin I-set domain	Domain
  PF07679	I-set	34061 → 34150	Immunoglobulin I-set domain	Domain
  PF07679	I-set	34256 → 34347	Immunoglobulin I-set domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Isoforms 3, 7 and 8 are expressed in cardiac muscle. Isoform 4 is expressed in vertebrate skeletal muscle. Isoform 6 is expressed in skeletal muscle (at protein level). {ECO:0000269|PubMed:11717165, ECO:0000269|PubMed:7819249}.
• Sequence:

  MTTQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSD
  GRAKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQ
  VRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATN
  SVGRATSTAELLVQGEEEVPAKKTKTIVSTAQISESRQTRIEKKIEAHFDARSIATVEMV
  IDGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPT
  PSPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPPWKQEGYVASSSEAEMR
  ETTLTTSTQIRTEERWEGRYGVQEQVTISGAAGAAASVSASASYAAEAVATGAKEVKQDA
  DKSAAVATVVAAVDMARVREPVISAVEQTAQRTTTTAVHIQPAQEQVRKEAEKTAVTKVV
  VAADKAKEQELKSRTKEVITTKQEQMHVTHEQIRKETEKTFVPKVVISAAKAKEQETRIS
  EEITKKQKQVTQEAIRQETEITAASMVVVATAKSTKLETVPGAQEETTTQQDQMHLSYEK
  IMKETRKTVVPKVIVATPKVKEQDLVSRGREGITTKREQVQITQEKMRKEAEKTALSTIA
  VATAKAKEQETILRTRETMATRQEQIQVTHGKVDVGKKAEAVATVVAAVDQARVREPREP
  GHLEESYAQQTTLEYGYKERISAAKVAEPPQRPASEPHVVPKAVKPRVIQAPSETHIKTT
  DQKGMHISSQIKKTTDLTTERLVHVDKRPRTASPHFTVSKISVPKTEHGYEASIAGSAIA
  TLQKELSATSSAQKITKSVKAPTVKPSETRVRAEPTPLPQFPFADTPDTYKSEAGVEVKK
  EVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESV
  TLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNE
  AGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRDVVMTDTSLTEEQAGPGEPA
  APYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECK
  LVISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTAFVQEP
  KVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQEFHISSFEERLIKEIEY
  RIIKTTLEELLEEDGEEKMAVDISESEAVESGFDSRIKNYRILEGMGVTFHCKMSGYPLP
  KIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIYTAFASNIKGNAICSGKLY
  VEPAAPLGAPTYIPTLEPVSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPG
  RRLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVND
  YTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE
  KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDST
  VSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEPEPERKLIIPRGTYRAKEIAAPELEPL
  HLRYGQEQWEEGDLYDKEKQQKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLH
  DGKPLEAANRLRMINEFGYCSLDYGVAYSRDSGIITCRATNKYGTDHTSATLIVKDEKSL
  VEESQLPEGRKGLQRIEELERMAHEGALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARF
  RCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEGV
  IEHKVKLEIQQREDFRSVLRRAPEPRPEFHVHEPGKLQFEVQKVDRPVDTTETKEVVKLK
  RAERITHEKVPEESEELRSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRKTKDELLH
  WTKELTEEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVR
  VVGKPDPECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAGET
  SSHAFLLVQAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKY
  RMHSDRKVHFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPE
  SYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVI
  DGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDR
  VHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGT
  KAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVG
  RVETNCNLSVEKIKIIRGLRDLTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKI
  EAHGKIYKLTVLNMMKDDEGKYTFYAGENMTSGKLTVAGGAISKPLTDQTVAESQEAVFE
  CEVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVATSKTSA
  KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGT
  IYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVAFEVSVSH
  DTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKAKLFVE
  TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLII
  MNTSTEDSAEYTFVCGNDQVSATLTVTPIMITSMLKDINAEEKDTITFEVTVNYEGISYK
  WLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKATSTATLYVEARHIEF
  RKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTR
  MSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWY
  KDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQ
  VLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIE
  AFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQ
  PARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASN
  AVGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLSKINET
  LELLSESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNG
  VLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHK
  DTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQ
  LCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTD
  TPCKAKSTPEAPEDFPQTPLKGPAVEALDSEQEIATFVKDTILKAALITEENQQLSYEHI
  AKANELSSQLPLGAQELQSILEQDKLTPESTREFLCINGSIHFQPLKEPSPNLQLQIVQS
  QKTFSKEGILMPEEPETQAVLSDTEKIFPSAMSIEQINSLTVEPLKTLLAEPEGNYPQSS
  IEPPMHSYLTSVAEEVLSPKEKTVSDTNREQRVTLQKQEAQSALILSQSLAEGHVESLQS
  PDVMISQVNYEPLVPSEHSCTEGGKILIESANPLENAGQDSAVRIEEGKSLRFPLALEEK
  QVLLKEEHSDNVVMPPDQIIESKREPVAIKKVQEVQGRDLLSKESLLSGIPEEQRLNLKI
  QICRALQAAVASEQPGLFSEWLRNIEKVEVEAVNITQEPRHIMCMYLVTSAKSVTEEVTI
  IIEDVDPQMANLKMELRDALCAIIYEEIDILTAEGPRIQQGAKTSLQEEMDSFSGSQKVE
  PITEPEVESKYLISTEEVSYFNVQSRVKYLDATPVTKGVASAVVSDEKQDESLKPSEEKE
  ESSSESGTEEVATVKIQEAEGGLIKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNW
  YFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKR
  AAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSL
  EILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICT
  VTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADI
  CQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKIC
  FEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGE
  SARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAV
  NDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRS
  SKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDL
  IALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGK
  YTCLAENEAGSQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYKD
  GRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAP
  FFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEII
  RVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGST
  PLTIRWFKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANL
  FVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVES
  TAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEYDVMLL
  AEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGS
  SICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIR
  MTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQG
  DPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEV
  QNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQ
  EISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEK
  PQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKAT
  DSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRV
  SWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKVKE
  PPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVFNLH
  ITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAG
  SPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYA
  FLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYFSMSFEN
  NVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSS
  IHMECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSN
  VAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSG
  PKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASK
  IVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGD
  FICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKD
  KRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKEPPRFV
  SKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKA
  EPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPEL
  SVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDV
  SDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDN
  VCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFT
  SVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQ
  ASCTTRLFVKEPAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCN
  IVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVG
  DSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKA
  ENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGV
  LLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFF
  DIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKV
  GKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPE
  IKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALT
  VKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDT
  SLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAI
  VEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMR
  ECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHI
  TFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAI
  LGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTC
  VAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRE
  LVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRL
  ADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIED
  YAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISW
  YKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARK
  LPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATL
  QILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKC
  HVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKD
  SCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFR
  MSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKG
  ADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKA
  TNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIV
  RESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPE
  SIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDS
  GVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISV
  SWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVRE
  PPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELE
  LFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTG
  TPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSA
  QILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRN
  NVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLP
  VVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATN
  PIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREI
  RSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK
  RLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAG
  MNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSE
  PIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKV
  TIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWR
  QLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQVDERKKQEKI
  EGDLRAMLKKTPILKKGAGEEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELL
  KQSQEEETHRLEIEEIERSERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDA
  VFEIDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGP
  HIASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRHKTE
  VEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATF
  ECEVSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRG
  EARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPE
  EKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSK
  AEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPY
  YEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQ
  KEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKI
  VPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEK
  IHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPV
  PKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREE
  SPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPP
  RAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEE
  REEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIE
  EPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLP
  AKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVT
  EFRKRVVKEEKVSIEAPKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDY
  KEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAK
  VLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMK
  PKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEE
  EEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLI
  PKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKV
  EAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEI
  VPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEV
  LPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVL
  PVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPA
  KVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSV
  AFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEH
  RVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVP
  KKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVV
  PEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKK
  VPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEA
  IPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKK
  PELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPA
  KVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPE
  VPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV
  KEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVL
  RKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPA
  IPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPI
  KGVPKKTPSPIEAERRKLRPGSGGEKPPDEAPFTYQLKAVPLKFVKEIKDIILTESEFVG
  SSAIFECLVSPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLR
  LGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCELNKERDVVWRKDGKIVVE
  KPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIR
  DQHVKPKGTAIFACDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPED
  IAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKG
  ELLRPSPTCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLK
  DVTVPERRQARFECVLTREANVIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGV
  YTAEVEGKKTSARLFVTGIRLKFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKL
  HTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKT
  AVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVC
  DCGTDKTKANVTVEARLIKVEKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPLTAS
  PDCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPLIFITPLSDVKVFE
  KDEAKFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEA
  EDKHTSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRLHTTRS
  VSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKD
  EVILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGT
  DKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDCE
  IKEEGKIHSLVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETA
  TFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFK
  THANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIV
  ADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARF
  ECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSCEVRTARTS
  GMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEIIETGRYEILTE
  GRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNLEILEGEKAEFVC
  SISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAARAAAH
  LTVIEKLRIVVPLKDTRVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLV
  YTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTF
  WCKVNRLNVTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSV
  AELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKD
  GSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLA
  ELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAK
  LELAAAPKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTS
  FRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEP
  LTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTG
  EPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKT
  SIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPS
  PPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKV
  TGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPIT
  ILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRV
  KTISGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKT
  WTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPEN
  VKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEE
  GKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPAT
  VTGKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRAT
  AVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL
  SSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSD
  ITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKY
  RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGA
  KIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSD
  PVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV
  DTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVV
  DVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTE
  VQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGG
  SPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSE
  ISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRL
  TMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITK
  SSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRV
  KAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMG
  YIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTK
  AVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLV
  RRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAP
  CTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEWIVV
  TSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVED
  VTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYV
  FRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEI
  VGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPV
  TVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVID
  NVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMC
  LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKN
  KFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEK
  RRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEV
  PPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEV
  SRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAES
  CYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRV
  RAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGY
  WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPS
  DPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKR
  VNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFID
  IGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENS
  SVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWK
  MPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGI
  GPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAW
  DPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPVTVKD
  QTCPPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKL
  VVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQ
  MTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMA
  QNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWL
  EMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA
  TARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDK
  EVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQLDASVRDR
  IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVY
  SLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI
  EKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREP
  ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLS
  RKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRDKLTIRVG
  EAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVV
  ENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKE
  VGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPD
  APDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRV
  PDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTW
  QPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVN
  AAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWK
  KEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPP
  RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHL
  NEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKP
  DRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLP
  DTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKT
  DEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINI
  LDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCE
  YVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGS
  PITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSD
  PIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRI
  NKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVT
  CRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVR
  ADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEI
  TNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPIL
  AINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKG
  SIKETHYMVDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKPVLDLKLSGVLTV
  KAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGK
  YVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYIL
  EKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKY
  DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPER
  RMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSI
  TLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEY
  EFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGR
  PAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNV
  RVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK
  KTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKN
  SATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRV
  AARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWK
  KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG
  PPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRV
  GKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWD
  RPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG
  SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG
  DKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPP
  RIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTL
  ELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPL
  EDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDP
  VFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVN
  WTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPA
  FPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTG
  LMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRL
  YVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCG
  KKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSW
  STVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVR
  SVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTF
  RVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPS
  VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV
  GKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKT
  TFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVS
  LTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAI
  NLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKR
  DLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEY
  EAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPT
  SSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTW
  TPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYG
  KGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREK
  KSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPP
  GPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQF
  VVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLS
  IRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPA
  GKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS
  YSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNI
  MDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEY
  TFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRP
  KPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITI
  QVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTV
  IRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKD
  SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRV
  IAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIV
  EKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCR
  DDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA
  DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEKCV
  LSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVN
  KYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVER
  RDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTV
  FKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKA
  TSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIR
  ACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTV
  ENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRES
  TRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPG
  KITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQ
  GEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIG
  RPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETL
  NVIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSA
  TVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSS
  RDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEF
  RVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGY
  IVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAIT
  ARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIK
  STDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEK
  CTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMA
  VNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVL
  EKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACD
  PIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGI
  NKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKLEAPDIDLDLELRKIIN
  IRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTL
  TLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKR
  EATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQP
  PGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQAVITNL
  TQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPI
  SGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTA
  SIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVV
  SATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATA
  ISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEY
  EFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMIT
  GYIVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGP
  ITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCE
  IKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTS
  EKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRI
  MAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGY
  IVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKA
  CDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQT
  GLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKG
  IVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY
  ILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVID
  KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPP
  SPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVT
  GLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIEI
  PVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTA
  TENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIVEKRDTTTTTWH
  MVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFV
  TSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGL
  EYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSK
  ITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSS
  GAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAA
  RMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTG
  VTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYI
  FRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEI
  EGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVF
  YRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCT
  PPTGLQGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADL
  RKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDS
  GRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNY
  IVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVS
  EPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEA
  TISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK
  IDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSA
  GSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTT
  WHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTP
  KVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDE
  GLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGG
  AKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSE
  STGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEER
  ARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEIN
  GLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEY
  IFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSE
  ISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSP
  LIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTS
  IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMR
  KTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSG
  KYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYH
  IEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKITE
  KPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHV
  VSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSN
  LKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAAN
  SSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETS
  TAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPP
  STPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTT
  ISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAF
  DGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISN
  PSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKEL
  QTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPI
  EFKTVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKG
  NEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADG
  GSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSE
  PSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEW
  TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL
  DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQ
  VTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDG
  GSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCET
  TEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAG
  ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQV
  TVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGK
  YTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYS
  IEKRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQ
  FRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISG
  REYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITL
  KWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNA
  VGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWF
  KDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG
  KVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTA
  IKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWA
  RPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAA
  GVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMC
  KADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRLT
  APELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTL
  TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKDVTRGSATLMWDAPL
  LDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEP
  YEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWV
  EAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGIT
  NQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRG
  DSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEI
  TNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPII
  AEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKV
  PCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRS
  TVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYE
  FRVLAKNAAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGG
  KPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSV
  MVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGE
  CPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGK
  EHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQF
  RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDI
  VGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIA
  EIEPVERIEIPDLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAII
  DTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDS
  VTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLP
  ENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA
  CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR
  VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV
  AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW
  EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFG
  IGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEV
  RADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPP
  GKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYT
  LTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGV
  IRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKC
  GKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKA
  AWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPS
  NPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTG
  LVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEK
  PECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGL
  SRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKEL
  IQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYP
  LKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQR
  KTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGS
  WITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQNTFGISDPLEVS
  SVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWIS
  VTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEE
  LRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVT
  DDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSG
  KPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKT
  VELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQ
  ARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDEEVDETRE
  VSMTKASHSSTKELYEKYMIAEDLGRGEFGIVHRCVETSSKKTYMAKFVKVKGTDQVLVK
  KEISILNIARHRNILHLHESFESMEELVMIFEFISGLDIFERINTSAFELNEREIVSYVH
  QVCEALQFLHSHNIGHFDIRPENIIYQTRRSSTIKIIEFGQARQLKPGDNFRLLFTAPEY
  YAPEVHQHDVVSTATDMWSLGTLVYVLLSGINPFLAETNQQIIENIMNAEYTFDEEAFKE
  ISIEAMDFVDRLLVKERKSRMTASEALQHPWLKQKIERVSTKVIRTLKHRRYYHTLIKKD
  LNMVVSAARISCGGAIRSQKGVSVAKVKVASIEIGPVSGQIMHAVGEEGGHVKYVCKIEN
  YDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSY
  AELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKTAYVGENVRFGVTI
  TVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNKYGE
  DSCKAKLTVTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDG
  

• Sequence length: 34350

Pathways

KEGG:

Cytoskeleton in muscle cells
Hypertrophic cardiomyopathy
Dilated cardiomyopathy

Reactome:

Platelet degranulation
Striated Muscle Contraction

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Associated diseases

Causal
Disease merge term	Disease name	dbSNP ID	References
Arrhythmogenic right ventricular cardiomyopathy	Arrhythmogenic right ventricular dysplasia 1	rs766450773	N/A
cardiomyopathy	Cardiomyopathy	rs2060187635, rs397517735, rs971618751, rs730880365, rs371678190, rs1559556267, rs886043718, rs746115846, rs553526525, rs727504825, rs748313513, rs794729354, rs1064792916, rs1559746821, rs764243269, rs397517633, rs397517689, rs368452607, rs869312054, rs1559873786, rs869320740, rs751502842, rs869312085, rs1285329277, rs876657666, rs1553611989, rs869025556, rs794729278, rs397517601, rs1561323791, rs886038928, rs1205836993, rs749961489, rs869312116, rs766265889, rs797046064, rs1575872984, rs1561445221, rs557312035, rs769665204, rs869312055, rs727505319, rs1559712733, rs72646846, rs1243301263, rs727504466, rs1558988204, rs794729301, rs886044536, rs774604740, rs869178171, rs1559051231, rs1553488049, rs727503607, rs869312112, rs794729332, rs727504851, rs1575614351, rs1559262463, rs397517626, rs751746401, rs876657670, rs1559448864, rs1553644307, rs869038795, rs1322596650, rs1576018303, rs776970935, rs794729380, rs72648222, rs753948675, rs1559469421, rs1553663867	N/A
Cardiomyopathy	Primary dilated cardiomyopathy, left ventricular noncompaction cardiomyopathy, Primary familial dilated cardiomyopathy	rs397517689, rs869312083, rs869312059, rs974671846, rs876657669, rs1266489077, rs727504856, rs869025552, rs869312113, rs869312077, rs727504825, rs397517587, rs727504843, rs1575799625, rs869312041, rs869312118, rs869312052, rs1575796530, rs869025545, rs794729284, rs764243269, rs397517633, rs730880243, rs869312084, rs869312060, rs876657668, rs1575610911, rs1553539995, rs869025548, rs587782986, rs869312114, rs368452607, rs869312078, rs991187915, rs869312102, rs869312066, rs397517589, rs1575285509, rs1553662326, rs727504452, rs869312042, rs730880365, rs869312119, rs869312054, rs1574659116, rs371678190, rs869312108, rs1060500575, rs1553940122, rs730880242, rs794729265, rs869312085, rs112240298, rs747662439, rs770038577, rs876657666, rs1708504899, rs727504782, rs869025556, rs727503537, rs869312115, rs1576014673, rs869312079, rs1575649368, rs727503565, rs397517741, rs869312103, rs869312067, rs397517601, rs727503697, rs869312044, rs727504646, rs869312120, rs770878165, rs878854371, rs1060500505, rs1553603152, rs869312109, rs1559003939, rs397517643, rs730880241, rs748382770, rs727504660, rs727504535, rs869312116, rs1576147786, rs869312080, rs869312121, rs727504655, rs397517749, rs869312104, rs794729353, rs869312068, rs727503598, rs869312046, rs727505014, rs574660186, rs869312055, rs1553503113, rs267607156, rs1575512482, rs727503586, rs869025558, rs869312110, rs397517695, rs794729365, rs886043924, rs397517547, rs2054381012, rs557312035, rs1477669354, rs770029258, rs747469275, rs1060500562, rs1064796347, rs727505352, rs397517750, rs869312069, rs397517620, rs727503602, rs373040154, rs727505288, rs1553691320, rs876657672, rs727505319, rs869025557, rs869312111, rs794729338, rs926741242, rs768345594, rs886038928, rs72646846, rs772121356, rs794729320, rs397517696, rs869312086, rs773840992, rs869312061, rs876657665, rs869312028, rs774604740, rs869312122, rs1575253896, rs727504466, rs766265889, rs397517758, rs869312105, rs771562210, rs397517624, rs727503607, rs869312047, rs727503557, rs1553577362, rs876657671, rs1161735211, rs200797552, rs755261062, rs1559598775, rs869312081, rs869312087, rs869312062, rs876657664, rs397517576, rs727505284, rs1575584918, rs727504550, rs794729325, rs1575616801, rs751039219, rs397517776, rs869312106, rs869312070, rs397517626, rs727503559, rs777602537, rs1553603456, rs868494032, rs1576141328, rs727503547, rs869025550, rs869312112, rs1559415567, rs397517698, rs869312100, rs869312063, rs727504851, rs869312037, rs727504679, rs794729324, rs869312045, rs1575775337, rs1131691873, rs727504531, rs869025555, rs770767998, rs869312071, rs869312048, rs869312082, rs730880245, rs869312056, rs1553741321, rs876657670, rs906494713, rs727505076, rs869025549, rs869312074, rs879139686, rs397517721, rs779129892, rs757451467, rs869312064, rs876657663, rs397517580, rs971618751, rs869312038, rs727503546, rs869312117, rs730880343, rs1419374180, rs1575948935, rs1131691655, rs869025546, rs794729285, rs1060500495, rs759231562, rs1695435412, rs1389777522, rs727504184, rs869312049, rs72648250, rs869312057, rs1553479603, rs727505224, rs869312075, rs1559877046, rs397517664, rs1064793814, rs869312065, rs974510652, rs397517584, rs727504589, rs1575614351, rs869312039, rs779996703, rs869312050, rs753948675, rs1574083547, rs727503567, rs869025554, rs397517787, rs869312107, rs869312072, rs397517628, rs730880246, rs112188483, rs886042331, rs869312058, rs1553607425, rs780512337, rs1576685753, rs727503552, rs869025544, rs763824247, rs869312076, rs397517679, rs727503615, rs397517735, rs756367933, rs794729359, rs397517586, rs727504499, rs869312040, rs764985774, rs754866489, rs869312051, rs267607155, rs1574087037, rs1408345511, rs869025559, rs397517830, rs775186117, rs869312073, rs72646831, rs1699247877, rs72648265	N/A
Centronuclear Myopathy	centronuclear myopathy	rs794729338, rs574660186, rs926741242, rs2093158866, rs2070649864, rs878854372	N/A
Dilated Cardiomyopathy	Dilated cardiomyopathy 1G, Dilated cardiomyopathy 1S, Dilated cardiomyopathy 1A	rs794729305, rs1322596650, rs570046043, rs794729280, rs1060500442, rs553526525, rs754866489, rs1576251664, rs1064793911, rs794729311, rs756367933, rs794729356, rs780415493, rs869312065, rs878854433, rs1553636843, rs1553682760, rs202094100, rs1477101279, rs1553524807, rs775186117, rs1060500572, rs1553692435, rs878854315, rs769664554, rs2060187635, rs794729367, rs1064792914, rs1064793845, rs1559321340, rs397517735, rs747286444, rs878854432, rs1553693444, rs1553603152, rs794729284, rs886037909, rs1703664543, rs1060500489, rs1483931960, rs1064796112, rs1559449398, rs771511344, rs794729384, rs545954490, rs1553562793, rs1114167323, rs371678190, rs869025545, rs794729339, rs1060500575, rs886038916, rs1559301344, rs2092847994, rs397517689, rs1396898734, rs886043924, rs770038577, rs1218695159, rs1064792915, rs752948913, rs766265889, rs1553692107, rs1114167324, rs1553636324, rs1060500405, rs764243269, rs747236787, rs886055237, rs869312085, rs1250461669, rs876657666, rs794729278, rs869312121, rs869312104, rs1200988060, rs1476017129, rs1213930919, rs574660186, rs1114167335, rs869312055, rs869320740, rs1559598775, rs1708864326, rs794729365, rs1553504889, rs768431507, rs747469275, rs794729343, rs1060500544, rs767450912, rs1466647934, rs1114167333, rs1553754743, rs781540455, rs768345594, rs886038831, rs1330960948, rs374140736, rs769488730, rs886044536, rs1553565316, rs769097909, rs869312028, rs774604740, rs1064793419, rs1553539391, rs1085307600, rs794729382, rs1060500514, rs1553649171, rs869312047, rs869312081, rs1553939749, rs267607158, rs869320741, rs794729281, rs1060500479, rs72646846, rs2051361827, rs760915007, rs1553659902, rs1578126437, rs752697861, rs72648224, rs1575540533, rs1064796323, rs727503559, rs397517776, rs794729286, rs1553614378, rs878854335, rs397517626, rs772061676, rs1553661994, rs886039027, rs1553482872, rs751319893, rs1343120755, rs794729319, rs1057518195, rs1553703310, rs1574982376, rs794729324, rs776065839, rs2147483647, rs727504531, rs770767998, rs1553524697, rs878854332, rs376799532, rs774395395, rs1553501572, rs1575283255, rs869025549, rs869312112, rs794729332, rs1553643260, rs2052563186, rs794729300, rs1574066113, rs1219954334, rs727503546, rs794729323, rs769912484, rs1419374180, rs267607155, rs1553882262, rs1060500593, rs72648250, rs794729331, rs1060500420, rs1064795407, rs1057522256, rs971618751, rs878854281, rs1553628052, rs779996703, rs1553490574, rs794729285, rs1060500399, rs878854322, rs869038795	N/A
Hypertrophic Cardiomyopathy	Hypertrophic cardiomyopathy 9	rs974671846, rs878854428, rs1213930919, rs869320740, rs1709195189, rs28933405	N/A
Hypertrophic cardiomyopathy	hypertrophic cardiomyopathy	rs1198682781	N/A
Left ventricular noncompaction	left ventricular noncompaction 2	rs1114167338, rs794729390	N/A
Limb-girdle muscular dystrophy	Autosomal recessive limb-girdle muscular dystrophy type 2J	rs756339648, rs1575285509, rs543860009, rs281864927, rs281864930, rs1009131948, rs557526069, rs1200988060, rs1553775212, rs397517643, rs1559446852, rs375159973, rs534484592, rs1250461669, rs397517547, rs1577824925, rs727504535, rs1574817395, rs281864928, rs760915007, rs887577241, rs869312122, rs1553482872, rs876657664, rs777924443, rs1688921542, rs794727544, rs1559267059, rs779129892, rs878854324, rs767120669, rs1575185742	N/A
multiminicore myopathy	Multiminicore myopathy	rs1703164675	N/A
Muscular dystrophy	muscular dystrophy	rs886039913	N/A
Myofibrillar myopathy	Myopathy, myofibrillar, 9, with early respiratory failure	rs281864930, rs869320743, rs1560689563, rs869320740, rs1064793560, rs878854428, rs1553636324, rs1553501227, rs869320741, rs786205367, rs1559187287, rs869320742, rs753334568	N/A
Myopathy	myopathy	rs797046064, rs797046060, rs1198364572, rs1057518851	N/A
Myopathy With Fatal Cardiomyopathy	early-onset myopathy with fatal cardiomyopathy	rs1250336644, rs746115846, rs1553809971, rs375159973, rs1554015228, rs1064793560, rs397517576, rs587776772, rs769912484, rs397517776, rs199469665, rs794729285, rs2060187635, rs1576251664	N/A
Tibial muscular dystrophy	tibial muscular dystrophy	rs587780495, rs543860009, rs281864927, rs2067087661, rs281864933, rs267607156, rs281864932, rs878854428, rs751502842, rs770038577, rs1553707780, rs281864928, rs281864930	N/A
Atrioventricular block	Third degree atrioventricular block	rs766840243, rs763809932	N/A
Feingold Syndrome	feingold syndrome type 1	rs574660186	N/A
Noncompaction cardiomyopathy	noncompaction cardiomyopathy	rs1553915256	N/A
Wolff-Parkinson-White Syndrome	Wolff-Parkinson-White pattern	rs1553624186, rs869312065	N/A

Unknown
Disease merge term	Disease name	Evidence	References	Source
Atrial Fibrillation	atrial fibrillation, Atrial fibrillation	N/A	N/A	ClinVar, GWAS
Brugada Syndrome	brugada syndrome	N/A	N/A	ClinVar
Catecholaminergic Polymorphic Ventricular Tachycardia	catecholaminergic polymorphic ventricular tachycardia	N/A	N/A	ClinVar
Congenital Long QT Syndrome	congenital long qt syndrome	N/A	N/A	ClinVar
Congenital Multicore Myopathy With External Ophthalmoplegia	congenital multicore myopathy with external ophthalmoplegia	N/A	N/A	ClinVar
congenital myopathy	Congenital myopathy	N/A	N/A	ClinVar
Congestive Heart Failure	congestive heart failure	N/A	N/A	ClinVar
Diabetes	Type 2 diabetes	N/A	N/A	GWAS
Heart Failure	heart failure	N/A	N/A	ClinVar
Left Ventricular Hypertrophy	left ventricular hypertrophy	N/A	N/A	ClinVar
Long QT Syndrome	long qt syndrome	N/A	N/A	ClinVar
Myopathy With Postural Muscle Atrophy, X-Linked	x-linked myopathy with postural muscle atrophy	N/A	N/A	ClinVar
Orofacial Cleft	orofacial cleft 1	N/A	N/A	ClinVar
Restrictive cardiomyopathy	Familial restrictive cardiomyopathy, restrictive cardiomyopathy	N/A	N/A	ClinVar
Sick Sinus Syndrome	Sick sinus syndrome	N/A	N/A	GWAS
Ventricular Fibrillation	ventricular fibrillation, Ventricular fibrillation, paroxysmal familial, type 1	N/A	N/A	ClinVar
ventricular tachycardia	Ventricular tachycardia	N/A	N/A	ClinVar

Associations from Text Mining
Disease Name	Relationship Type	References
Adenocarcinoma of Lung	Associate	30075702, 33619234, 38013642, 38166691
Adenoma	Associate	29575536
Adrenal Insufficiency	Associate	26315439
Alzheimer Disease	Associate	19902006
Aortic Diseases	Associate	19154184
Aortic Valve Stenosis	Associate	19154184
Arrhythmias Cardiac	Associate	27321809, 31251381, 34338756, 40088216
Arrhythmogenic Right Ventricular Dysplasia	Associate	21810661, 25157032, 25445213, 29221435, 29750433, 36037555
Arthrogryposis	Associate	24105469, 31660661, 35605965, 36977548, 39684706
Arthrogryposis multiplex congenita distal type 1	Associate	36945066
Atrial Fibrillation	Associate	29290336, 29568937, 30535219, 31251381, 31691645, 32572052, 33682005, 36637017, 36669898, 39453294, 39851047
Atrial Remodeling	Associate	21810661
Autism Spectrum Disorder	Associate	31838722
Bicuspid Aortic Valve Disease	Associate	36071494
Blood Protein Disorders	Associate	35893073
Bohring syndrome	Associate	32969603, 37461109
Breast Neoplasms	Associate	26920143, 27153670, 33179096, 34888385, 36805828, 37454130
Bulbo Spinal Atrophy X Linked	Associate	36376797
Capillary Malformation Arteriovenous Malformation	Associate	33449170
Carcinogenesis	Associate	29575536, 32820147, 33179096
Carcinoma Acinar Cell	Associate	34629449
Carcinoma Hepatocellular	Associate	28700999, 30046591, 32017470, 33861762, 36153509
Cardiomyopathies	Associate	16352453, 24105469, 26735901, 27511179, 29997384, 30021846, 31243866, 31664938, 32815318, 33226272, 33595762, 33682005, 33870097, 34338756, 34461741, 34618459, 35544052, 35581137, 36012532, 36037555, 36548481, 36637017, 36977548, 37622577, 37904158, 37967257
Cardiomyopathy Alcoholic	Associate	29773157
Cardiomyopathy Dilated	Associate	15582318, 22335739, 22763267, 22892539, 23418287, 23463027, 24105469, 24119082, 24503780, 25589632, 25961010, 26084686, 26315439, 26567375, 26701604, 26735901, 27625338, 27813223, 28045975, 28296976, 28423146, 29073955, 29386531, 29523227, 29773157, 30150400, 30165862, 30332462, 30851055, 30858397, 31216868, 31251381, 31489791, 31583969, 31712709, 31983221, 32005173, 32041989, 32371228, 32382064, 32603605, 32815318, 32964742, 33135063, 33445410, 33610015, 33678800, 33941202, 34088019, 34137518, 34213952, 34273475, 34461741, 34486814, 34731015, 34905694, 35138330, 35728000, 35741855, 36037555, 36270069, 36472615, 36495114, 36525964, 36637017, 37032351, 37191081, 37230314, 37461109, 37477868, 37526719, 37904158, 37914990, 37962957, 37999665, 38052212, 38226618, 38235591, 39425739, 40088216
Cardiomyopathy Dilated with Left Ventricular Noncompaction	Associate	29447731, 30371277, 35893073
Cardiomyopathy Hypertrophic	Associate	16352453, 22763267, 28223422, 28771489, 28797094, 32344918, 36037555, 37499109
Cardiomyopathy Hypertrophic Familial	Associate	36304977
Cardiomyopathy Restrictive	Associate	36037555
Cardiotoxicity	Associate	26758806
Cardiovascular Diseases	Associate	32371228
Cholangiocarcinoma	Associate	32801339, 34903127
Cholesteatoma Congenital	Associate	26335306
Cleft Palate	Associate	37967257
Colonic Neoplasms	Associate	35151825
Colorectal Neoplasms	Associate	32859214, 33624434
Colorectal Neoplasms	Inhibit	37499109
Congenital Abnormalities	Associate	36525964
Congenital heart block	Associate	28018021
Contracture	Associate	26581302, 31660661, 33449170, 35605965
Crisponi syndrome	Associate	26329309
Death	Associate	29523227
Death Sudden	Associate	21810661, 24119082, 32101375, 33445410
Death Sudden Cardiac	Associate	21810661, 26516846, 27321809, 32973354, 33445410
Dermatomyositis	Associate	20186858
Diabetes Mellitus Type 1	Associate	33029194
Diabetes Mellitus Type 2	Associate	37072623
Diabetic Nephropathies	Associate	34545296
Disease	Associate	21810661, 35177841
Distal Myopathies	Associate	12145747, 19797833, 20634290, 22577215, 24618559, 28295036, 29435569
Distal myopathy Nonaka type	Associate	40033712
Down Syndrome	Associate	19902006
Dyskinesia Familial with Facial Myokymia	Associate	22577215
Ehlers Danlos Syndrome	Associate	22223454
Endometrial Neoplasms	Associate	32945477
Fabry Disease	Associate	37914990
familial dilated cardiomyopathy	Associate	28045975, 28296976, 31587567, 33678800, 34618459, 37032351, 37999665
Fasciculation	Associate	12145747, 29435569, 32039858, 37999665
Fatigue	Associate	36376797
Fibrosis	Associate	24726255
Gait Disorders Neurologic	Associate	31489791
Genetic Diseases Inborn	Associate	32039858, 32973354, 36012532, 38052212
Glioma	Associate	35676651
Glomerulonephritis IGA	Associate	37914990
Glucose Galactose Malabsorption	Associate	9546812
Hallux Valgus	Associate	33926255
Heart Block	Associate	27511179, 28018021
Heart Defects Congenital	Associate	36977548
Heart Diseases	Associate	20383812, 21810661, 22736676, 24105469, 24630725, 27511179, 29518215, 29523227, 31216868, 33170376, 33449170, 33595762, 38226618, 39967429
Heart Failure	Associate	24119082, 25637629, 30851055, 31554410, 33583186, 33678800, 37914935
Heart Failure Diastolic	Associate	29889873
Heart Failure Systolic	Associate	37191081
Hepatitis B	Associate	28700999
Hereditary Myopathy with Early Respiratory Failure	Associate	23486992, 23514108, 27511179, 30666435, 34670883, 40033712
Hernia Inguinal	Associate	27115767
Hernias Diaphragmatic Congenital	Associate	16339921
Hypertension	Associate	25637629, 37451613
Hypertrophy	Associate	29523227
Hypertrophy Right Ventricular	Associate	28323875
Hypomagnesemia primary	Associate	26581302
Hypophosphatasia	Associate	39519277
Hypoxia	Associate	37239452, 38013642
Isolated Noncompaction of the Ventricular Myocardium	Associate	30471092, 30851055
Kidney Calculi	Stimulate	40253023
Kidney Failure Chronic	Associate	25589632
Leukemia Large Granular Lymphocytic	Associate	35015834
Leukemic Infiltration	Associate	40033712
Light Fixation Seizure Syndrome	Associate	29792937
Limb girdle muscular dystrophy autosomal recessive	Associate	31664938
Limbal Stem Cell Deficiency	Associate	30332462
Lung Neoplasms	Associate	36653483, 39413743
Lymphatic Metastasis	Associate	36653483
Lymphedema	Associate	31353864, 36945066, 39684706
Lymphedema Congenital Recessive	Associate	32778822, 33449170
Melanoma	Associate	23770775, 37377956, 39240165
Melanoma Cutaneous Malignant	Associate	32820147, 39240165
Mental Disorders	Associate	22363459, 37301943
Metabolic Syndrome	Associate	35177841
Migraine Disorders	Associate	31251381
Mouth Neoplasms	Associate	39337369
Multiple Myeloma	Associate	23770775
Muscle Hypotonia	Associate	35605965, 39684706
Muscle Neoplasms	Associate	22577215, 35605965
Muscle Weakness	Associate	22223454, 22577215, 31489791, 32778822, 33449170, 36945066
Muscular Diseases	Associate	27854218, 29435569, 31332964, 31489791, 31660661, 32815318, 33449170, 33870097, 34670883, 35580751, 35605965, 36037555, 36977548, 37999665, 39851047, 39967429, 40033712
Muscular Disorders Atrophic	Associate	20186858
Muscular Dystrophies	Associate	29435569, 29792937, 32815318, 40033712
Muscular Dystrophies Limb Girdle	Associate	20634290, 31664938
Muscular Dystrophy Duchenne	Associate	37671549
Myasthenia Gravis	Associate	20926005, 8669470, 9546812
Myofibrillar Myopathy	Associate	23486992, 39973468
Myopathies Nemaline	Associate	30040739
Myopathies Structural Congenital	Associate	23975875, 33170376, 33870097, 37364426
Myopathy Central Core	Associate	24105469
Myositis	Associate	34499219
Myotonia Congenita	Associate	23975875, 29435569, 31332964, 31353864, 31664938, 32778822, 33127292, 33449170, 35605965, 36945066, 39684706, 40033712
Myotonic Dystrophy	Associate	34371182
Neoplasm Metastasis	Associate	32820147, 32945477, 34903127
Neoplasm Metastasis	Stimulate	37499109
Neoplasms	Associate	31092729, 32017470, 33179096, 34090483, 34946814, 37239452, 37454130, 37730847, 38217005, 39337369, 40420762
Neoplasms	Stimulate	33624434
Neoplasms Squamous Cell	Associate	39337369
Neoplastic Syndromes Hereditary	Associate	22577215, 24444549, 32912888, 34495297
Neuroblastoma	Associate	36037157
Neurofibromatosis Noonan syndrome	Associate	34312993
Neuromuscular Diseases	Associate	30040739, 32403337, 33127292
Non Muscle Invasive Bladder Neoplasms	Associate	39817975
Norrie disease	Associate	25157032
Osteoporosis	Associate	32930132
Ovarian Diseases	Associate	37239452
Ovarian Neoplasms	Associate	30786925
Pancreatic Neoplasms	Associate	33144687, 35638462
Paralyses Familial Periodic	Associate	30838349
Parkinson Disease	Associate	31827228
Pena Shokeir syndrome type 1	Associate	36495114
Polypoidal Choroidal Vasculopathy	Associate	34312993
Pre Eclampsia	Associate	30021846
Proteostasis Deficiencies	Associate	36525964
Pulmonary Disease Chronic Obstructive	Associate	16840573
Respiratory Insufficiency	Associate	22577215, 23486992, 24444549, 30666435, 32912888, 34670883, 37364426
Rigid spine syndrome	Associate	36945066
Sarcoma Ewing	Associate	39486665
Scoliosis	Associate	33449170
Sick Sinus Syndrome	Associate	27511179, 29568937, 33580673
Signs and Symptoms Respiratory	Associate	33449170
Squamous Cell Carcinoma of Head and Neck	Associate	33390791, 37340028, 37373553, 39337369
Stiff Skin Syndrome	Associate	25637629, 29523227
Stomach Neoplasms	Associate	32034058, 34761007
Sudden Infant Death	Associate	39425739
Sudden Unexpected Death in Epilepsy	Associate	28704380
Tachycardia Atrioventricular Nodal Reentry	Associate	27511179
Tachycardia Supraventricular	Associate	27511179
Tachycardia Ventricular	Associate	39453294
Tetralogy of Fallot	Stimulate	12393179
Thymic epithelial tumor	Associate	8669470
Thyroid Neoplasms	Associate	35766333
Triple Negative Breast Neoplasms	Associate	33179096, 40133516
Urinary Bladder Neoplasms	Associate	32012118, 32239176, 35087173, 40043910
Ventricular Dysfunction Left	Associate	29447731, 36304977, 39453294
Ventricular Dysfunction Right	Associate	34273475
Ventricular Fibrillation	Associate	18811803, 24119082, 31251381, 39453294
Ventricular Remodeling	Associate	29386531, 30275597, 34273475