Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	7188
Gene name	TNF receptor associated factor 5
Gene symbol	TRAF5
Synonyms (NCBI Gene)	MGC:39780RNF84
Chromosome	1
Chromosome location	1q32.3
Summary	The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF protei

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SNP ID	Visualize variation	Clinical significance	Consequence
rs756183569	AGAG>-	Likely-pathogenic	Frameshift variant, coding sequence variant, genic downstream transcript variant

380

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miRTarBase ID	miRNA	Experiments	Reference
MIRT553425	hsa-miR-8485	PAR-CLIP	21572407
MIRT553424	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT553423	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT553422	hsa-miR-603	PAR-CLIP	21572407
MIRT553421	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT553420	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT553419	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT553418	hsa-miR-567	PAR-CLIP	21572407
MIRT553417	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT553416	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT553415	hsa-miR-3941	PAR-CLIP	21572407
MIRT553414	hsa-miR-3924	PAR-CLIP	21572407
MIRT553413	hsa-miR-297	PAR-CLIP	21572407
MIRT553412	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT553411	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT465320	hsa-miR-383-5p	PAR-CLIP	23592263
MIRT465319	hsa-miR-3614-5p	PAR-CLIP	23592263
MIRT465318	hsa-miR-6500-3p	PAR-CLIP	23592263
MIRT465317	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT465315	hsa-miR-4459	PAR-CLIP	23592263
MIRT465316	hsa-miR-4433a-3p	PAR-CLIP	23592263
MIRT731422	hsa-miR-26b-5p	Luciferase reporter assay	26872428
MIRT731422	hsa-miR-26b-5p	Luciferase reporter assay	26872428
MIRT737074	hsa-miR-23a-3p	Luciferase reporter assayWestern blottingImmunohistochemistry (IHC)qRT-PCR	34249436
MIRT553425	hsa-miR-8485	PAR-CLIP	21572407
MIRT553424	hsa-miR-329-3p	PAR-CLIP	21572407
MIRT553423	hsa-miR-362-3p	PAR-CLIP	21572407
MIRT553422	hsa-miR-603	PAR-CLIP	21572407
MIRT553421	hsa-miR-4789-3p	PAR-CLIP	21572407
MIRT553420	hsa-miR-5011-5p	PAR-CLIP	21572407
MIRT553419	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT553418	hsa-miR-567	PAR-CLIP	21572407
MIRT553417	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT553416	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT553415	hsa-miR-3941	PAR-CLIP	21572407
MIRT553414	hsa-miR-3924	PAR-CLIP	21572407
MIRT553413	hsa-miR-297	PAR-CLIP	21572407
MIRT553412	hsa-miR-1277-5p	PAR-CLIP	21572407
MIRT553411	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT465320	hsa-miR-383-5p	PAR-CLIP	23592263
MIRT465319	hsa-miR-3614-5p	PAR-CLIP	23592263
MIRT465318	hsa-miR-6500-3p	PAR-CLIP	23592263
MIRT465317	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT465315	hsa-miR-4459	PAR-CLIP	23592263
MIRT465316	hsa-miR-4433a-3p	PAR-CLIP	23592263
MIRT1451006	hsa-miR-1262	CLIP-seq
MIRT1451007	hsa-miR-153	CLIP-seq
MIRT1451008	hsa-miR-15a	CLIP-seq
MIRT1451009	hsa-miR-15b	CLIP-seq
MIRT1451010	hsa-miR-16	CLIP-seq
MIRT1451011	hsa-miR-181a	CLIP-seq
MIRT1451012	hsa-miR-181b	CLIP-seq
MIRT1451013	hsa-miR-181c	CLIP-seq
MIRT1451014	hsa-miR-181d	CLIP-seq
MIRT1451015	hsa-miR-195	CLIP-seq
MIRT1451016	hsa-miR-3145-5p	CLIP-seq
MIRT1451017	hsa-miR-3149	CLIP-seq
MIRT1451018	hsa-miR-329	CLIP-seq
MIRT1451019	hsa-miR-365	CLIP-seq
MIRT1451020	hsa-miR-410	CLIP-seq
MIRT1451021	hsa-miR-424	CLIP-seq
MIRT1451022	hsa-miR-4252	CLIP-seq
MIRT1451023	hsa-miR-4262	CLIP-seq
MIRT1451024	hsa-miR-4457	CLIP-seq
MIRT1451025	hsa-miR-448	CLIP-seq
MIRT1451026	hsa-miR-4504	CLIP-seq
MIRT1451027	hsa-miR-452	CLIP-seq
MIRT1451028	hsa-miR-4524	CLIP-seq
MIRT1451029	hsa-miR-4641	CLIP-seq
MIRT1451030	hsa-miR-4676-3p	CLIP-seq
MIRT1451031	hsa-miR-4701-3p	CLIP-seq
MIRT1451032	hsa-miR-4789-5p	CLIP-seq
MIRT1451033	hsa-miR-4795-5p	CLIP-seq
MIRT1451034	hsa-miR-494	CLIP-seq
MIRT1451035	hsa-miR-497	CLIP-seq
MIRT1451036	hsa-miR-499-3p	CLIP-seq
MIRT1451037	hsa-miR-499a-3p	CLIP-seq
MIRT1451038	hsa-miR-503	CLIP-seq
MIRT1451039	hsa-miR-508-5p	CLIP-seq
MIRT1451040	hsa-miR-513b	CLIP-seq
MIRT1451041	hsa-miR-520d-5p	CLIP-seq
MIRT1451042	hsa-miR-524-5p	CLIP-seq
MIRT1451043	hsa-miR-568	CLIP-seq
MIRT1451044	hsa-miR-646	CLIP-seq
MIRT1451045	hsa-miR-661	CLIP-seq
MIRT1451046	hsa-miR-766	CLIP-seq
MIRT1451047	hsa-miR-1827	CLIP-seq
MIRT1451048	hsa-miR-3120-5p	CLIP-seq
MIRT1451049	hsa-miR-34b	CLIP-seq
MIRT1451050	hsa-miR-3613-3p	CLIP-seq
MIRT1451051	hsa-miR-3664-3p	CLIP-seq
MIRT1451052	hsa-miR-3664-5p	CLIP-seq
MIRT1451053	hsa-miR-371-5p	CLIP-seq
MIRT1451054	hsa-miR-371b-5p	CLIP-seq
MIRT1451055	hsa-miR-3929	CLIP-seq
MIRT1451056	hsa-miR-4419b	CLIP-seq
MIRT1451057	hsa-miR-4433	CLIP-seq
MIRT1451058	hsa-miR-4452	CLIP-seq
MIRT1451059	hsa-miR-4478	CLIP-seq
MIRT1451026	hsa-miR-4504	CLIP-seq
MIRT1451060	hsa-miR-4649-3p	CLIP-seq
MIRT1451061	hsa-miR-4695-5p	CLIP-seq
MIRT1451062	hsa-miR-4722-5p	CLIP-seq
MIRT1451063	hsa-miR-4738-3p	CLIP-seq
MIRT1451033	hsa-miR-4795-5p	CLIP-seq
MIRT1451064	hsa-miR-485-5p	CLIP-seq
MIRT1451065	hsa-miR-501-3p	CLIP-seq
MIRT1451066	hsa-miR-502-3p	CLIP-seq
MIRT1451067	hsa-miR-510	CLIP-seq
MIRT1451068	hsa-miR-512-5p	CLIP-seq
MIRT1451069	hsa-miR-563	CLIP-seq
MIRT1451070	hsa-miR-659	CLIP-seq
MIRT1451071	hsa-miR-940	CLIP-seq
MIRT1451007	hsa-miR-153	CLIP-seq
MIRT1451008	hsa-miR-15a	CLIP-seq
MIRT1451009	hsa-miR-15b	CLIP-seq
MIRT1451010	hsa-miR-16	CLIP-seq
MIRT1451047	hsa-miR-1827	CLIP-seq
MIRT1451015	hsa-miR-195	CLIP-seq
MIRT1451072	hsa-miR-29a	CLIP-seq
MIRT1451073	hsa-miR-29b	CLIP-seq
MIRT1451074	hsa-miR-29c	CLIP-seq
MIRT1451075	hsa-miR-3119	CLIP-seq
MIRT1451076	hsa-miR-3122	CLIP-seq
MIRT1451077	hsa-miR-3140-3p	CLIP-seq
MIRT1451078	hsa-miR-3160-3p	CLIP-seq
MIRT1451079	hsa-miR-3166	CLIP-seq
MIRT1451080	hsa-miR-3678-3p	CLIP-seq
MIRT1451081	hsa-miR-3689a-3p	CLIP-seq
MIRT1451082	hsa-miR-3689c	CLIP-seq
MIRT1451083	hsa-miR-3913-5p	CLIP-seq
MIRT1451021	hsa-miR-424	CLIP-seq
MIRT1451084	hsa-miR-4311	CLIP-seq
MIRT1451057	hsa-miR-4433	CLIP-seq
MIRT1451025	hsa-miR-448	CLIP-seq
MIRT1451085	hsa-miR-4487	CLIP-seq
MIRT1451086	hsa-miR-450b-5p	CLIP-seq
MIRT1451028	hsa-miR-4524	CLIP-seq
MIRT1451087	hsa-miR-4728-5p	CLIP-seq
MIRT1451088	hsa-miR-4753-5p	CLIP-seq
MIRT1451089	hsa-miR-4771	CLIP-seq
MIRT1451033	hsa-miR-4795-5p	CLIP-seq
MIRT1451035	hsa-miR-497	CLIP-seq
MIRT1451090	hsa-miR-499a-5p	CLIP-seq
MIRT1451038	hsa-miR-503	CLIP-seq
MIRT1451091	hsa-miR-507	CLIP-seq
MIRT1451041	hsa-miR-520d-5p	CLIP-seq
MIRT1451042	hsa-miR-524-5p	CLIP-seq
MIRT1451092	hsa-miR-557	CLIP-seq
MIRT1451093	hsa-miR-558	CLIP-seq
MIRT1451094	hsa-miR-601	CLIP-seq
MIRT1451044	hsa-miR-646	CLIP-seq
MIRT1555184	hsa-miR-4797-5p	CLIP-seq
MIRT2134812	hsa-miR-1226	CLIP-seq
MIRT1451011	hsa-miR-181a	CLIP-seq
MIRT1451012	hsa-miR-181b	CLIP-seq
MIRT1451013	hsa-miR-181c	CLIP-seq
MIRT1451014	hsa-miR-181d	CLIP-seq
MIRT2134813	hsa-miR-216a	CLIP-seq
MIRT2134814	hsa-miR-216b	CLIP-seq
MIRT2134815	hsa-miR-218	CLIP-seq
MIRT2134816	hsa-miR-3148	CLIP-seq
MIRT2134817	hsa-miR-3660	CLIP-seq
MIRT2134818	hsa-miR-3682-5p	CLIP-seq
MIRT2134819	hsa-miR-382	CLIP-seq
MIRT2134820	hsa-miR-4256	CLIP-seq
MIRT1451023	hsa-miR-4262	CLIP-seq
MIRT2134821	hsa-miR-4279	CLIP-seq
MIRT2134822	hsa-miR-4328	CLIP-seq
MIRT2134823	hsa-miR-4477b	CLIP-seq
MIRT2134824	hsa-miR-4496	CLIP-seq
MIRT2134825	hsa-miR-4517	CLIP-seq
MIRT2134826	hsa-miR-4526	CLIP-seq
MIRT2134827	hsa-miR-4693-3p	CLIP-seq
MIRT2134828	hsa-miR-4693-5p	CLIP-seq
MIRT2134829	hsa-miR-4733-3p	CLIP-seq
MIRT2134830	hsa-miR-4799-5p	CLIP-seq
MIRT2134831	hsa-miR-491-3p	CLIP-seq
MIRT1451041	hsa-miR-520d-5p	CLIP-seq
MIRT1451042	hsa-miR-524-5p	CLIP-seq
MIRT2134832	hsa-miR-548an	CLIP-seq
MIRT2134833	hsa-miR-548g	CLIP-seq
MIRT2134834	hsa-miR-548m	CLIP-seq
MIRT2134835	hsa-miR-556-3p	CLIP-seq
MIRT2134836	hsa-miR-605	CLIP-seq
MIRT2134837	hsa-miR-636	CLIP-seq
MIRT2134838	hsa-miR-639	CLIP-seq
MIRT1451044	hsa-miR-646	CLIP-seq
MIRT2134839	hsa-miR-924	CLIP-seq
MIRT2356081	hsa-miR-1323	CLIP-seq
MIRT1451047	hsa-miR-1827	CLIP-seq
MIRT2134813	hsa-miR-216a	CLIP-seq
MIRT2134814	hsa-miR-216b	CLIP-seq
MIRT2356082	hsa-miR-3065-3p	CLIP-seq
MIRT1451076	hsa-miR-3122	CLIP-seq
MIRT2356083	hsa-miR-3187-3p	CLIP-seq
MIRT1451049	hsa-miR-34b	CLIP-seq
MIRT2356084	hsa-miR-3612	CLIP-seq
MIRT1451051	hsa-miR-3664-3p	CLIP-seq
MIRT1451081	hsa-miR-3689a-3p	CLIP-seq
MIRT1451082	hsa-miR-3689c	CLIP-seq
MIRT2134819	hsa-miR-382	CLIP-seq
MIRT1451083	hsa-miR-3913-5p	CLIP-seq
MIRT2356085	hsa-miR-3926	CLIP-seq
MIRT1451055	hsa-miR-3929	CLIP-seq
MIRT2134821	hsa-miR-4279	CLIP-seq
MIRT1451056	hsa-miR-4419b	CLIP-seq
MIRT1451057	hsa-miR-4433	CLIP-seq
MIRT2356086	hsa-miR-4435	CLIP-seq
MIRT1451058	hsa-miR-4452	CLIP-seq
MIRT2356087	hsa-miR-4455	CLIP-seq
MIRT2356088	hsa-miR-4470	CLIP-seq
MIRT1451059	hsa-miR-4478	CLIP-seq
MIRT2134824	hsa-miR-4496	CLIP-seq
MIRT1451060	hsa-miR-4649-3p	CLIP-seq
MIRT2356089	hsa-miR-4684-5p	CLIP-seq
MIRT1451061	hsa-miR-4695-5p	CLIP-seq
MIRT2356090	hsa-miR-4701-5p	CLIP-seq
MIRT1451062	hsa-miR-4722-5p	CLIP-seq
MIRT1451087	hsa-miR-4728-5p	CLIP-seq
MIRT1451064	hsa-miR-485-5p	CLIP-seq
MIRT1451067	hsa-miR-510	CLIP-seq
MIRT1451068	hsa-miR-512-5p	CLIP-seq
MIRT2356091	hsa-miR-548c-3p	CLIP-seq
MIRT2134834	hsa-miR-548m	CLIP-seq
MIRT2356092	hsa-miR-548o	CLIP-seq
MIRT2356093	hsa-miR-548s	CLIP-seq
MIRT2356094	hsa-miR-566	CLIP-seq
MIRT2356095	hsa-miR-588	CLIP-seq
MIRT2356096	hsa-miR-650	CLIP-seq
MIRT1451071	hsa-miR-940	CLIP-seq
MIRT1451076	hsa-miR-3122	CLIP-seq
MIRT1451081	hsa-miR-3689a-3p	CLIP-seq
MIRT1451082	hsa-miR-3689c	CLIP-seq
MIRT1451083	hsa-miR-3913-5p	CLIP-seq
MIRT2134821	hsa-miR-4279	CLIP-seq
MIRT1451057	hsa-miR-4433	CLIP-seq
MIRT1451025	hsa-miR-448	CLIP-seq
MIRT2134824	hsa-miR-4496	CLIP-seq
MIRT1451087	hsa-miR-4728-5p	CLIP-seq
MIRT2134834	hsa-miR-548m	CLIP-seq
MIRT2134813	hsa-miR-216a	CLIP-seq
MIRT2134814	hsa-miR-216b	CLIP-seq
MIRT2356082	hsa-miR-3065-3p	CLIP-seq
MIRT1451048	hsa-miR-3120-5p	CLIP-seq
MIRT1451076	hsa-miR-3122	CLIP-seq
MIRT1451050	hsa-miR-3613-3p	CLIP-seq
MIRT1451052	hsa-miR-3664-5p	CLIP-seq
MIRT1451081	hsa-miR-3689a-3p	CLIP-seq
MIRT1451082	hsa-miR-3689c	CLIP-seq
MIRT1451053	hsa-miR-371-5p	CLIP-seq
MIRT1451054	hsa-miR-371b-5p	CLIP-seq
MIRT1451083	hsa-miR-3913-5p	CLIP-seq
MIRT2356089	hsa-miR-4684-5p	CLIP-seq
MIRT1451087	hsa-miR-4728-5p	CLIP-seq
MIRT1451063	hsa-miR-4738-3p	CLIP-seq
MIRT2356091	hsa-miR-548c-3p	CLIP-seq
MIRT2462275	hsa-miR-619	CLIP-seq
MIRT2649595	hsa-miR-1256	CLIP-seq
MIRT2356081	hsa-miR-1323	CLIP-seq
MIRT1451007	hsa-miR-153	CLIP-seq
MIRT1451008	hsa-miR-15a	CLIP-seq
MIRT1451009	hsa-miR-15b	CLIP-seq
MIRT1451010	hsa-miR-16	CLIP-seq
MIRT1451047	hsa-miR-1827	CLIP-seq
MIRT1451015	hsa-miR-195	CLIP-seq
MIRT2649596	hsa-miR-2053	CLIP-seq
MIRT2134813	hsa-miR-216a	CLIP-seq
MIRT2134814	hsa-miR-216b	CLIP-seq
MIRT2134815	hsa-miR-218	CLIP-seq
MIRT2649597	hsa-miR-24	CLIP-seq
MIRT2649598	hsa-miR-298	CLIP-seq
MIRT2356082	hsa-miR-3065-3p	CLIP-seq
MIRT1451048	hsa-miR-3120-5p	CLIP-seq
MIRT1451076	hsa-miR-3122	CLIP-seq
MIRT2134816	hsa-miR-3148	CLIP-seq
MIRT2649599	hsa-miR-3154	CLIP-seq
MIRT2356083	hsa-miR-3187-3p	CLIP-seq
MIRT1451050	hsa-miR-3613-3p	CLIP-seq
MIRT1451019	hsa-miR-365	CLIP-seq
MIRT1451051	hsa-miR-3664-3p	CLIP-seq
MIRT1451052	hsa-miR-3664-5p	CLIP-seq
MIRT1451081	hsa-miR-3689a-3p	CLIP-seq
MIRT1451082	hsa-miR-3689c	CLIP-seq
MIRT1451053	hsa-miR-371-5p	CLIP-seq
MIRT1451054	hsa-miR-371b-5p	CLIP-seq
MIRT1451083	hsa-miR-3913-5p	CLIP-seq
MIRT2356085	hsa-miR-3926	CLIP-seq
MIRT1451055	hsa-miR-3929	CLIP-seq
MIRT1451020	hsa-miR-410	CLIP-seq
MIRT1451021	hsa-miR-424	CLIP-seq
MIRT1451056	hsa-miR-4419b	CLIP-seq
MIRT1451057	hsa-miR-4433	CLIP-seq
MIRT2356086	hsa-miR-4435	CLIP-seq
MIRT2649600	hsa-miR-4436a	CLIP-seq
MIRT2649601	hsa-miR-4437	CLIP-seq
MIRT2649602	hsa-miR-4453	CLIP-seq
MIRT1451024	hsa-miR-4457	CLIP-seq
MIRT2356088	hsa-miR-4470	CLIP-seq
MIRT2134823	hsa-miR-4477b	CLIP-seq
MIRT1451059	hsa-miR-4478	CLIP-seq
MIRT1451025	hsa-miR-448	CLIP-seq
MIRT2134825	hsa-miR-4517	CLIP-seq
MIRT1451028	hsa-miR-4524	CLIP-seq
MIRT2649603	hsa-miR-4538	CLIP-seq
MIRT1451029	hsa-miR-4641	CLIP-seq
MIRT2649604	hsa-miR-4642	CLIP-seq
MIRT1451060	hsa-miR-4649-3p	CLIP-seq
MIRT2356089	hsa-miR-4684-5p	CLIP-seq
MIRT1451061	hsa-miR-4695-5p	CLIP-seq
MIRT2356090	hsa-miR-4701-5p	CLIP-seq
MIRT1451062	hsa-miR-4722-5p	CLIP-seq
MIRT1451087	hsa-miR-4728-5p	CLIP-seq
MIRT1451063	hsa-miR-4738-3p	CLIP-seq
MIRT2134830	hsa-miR-4799-5p	CLIP-seq
MIRT1451064	hsa-miR-485-5p	CLIP-seq
MIRT1451034	hsa-miR-494	CLIP-seq
MIRT1451035	hsa-miR-497	CLIP-seq
MIRT1451036	hsa-miR-499-3p	CLIP-seq
MIRT1451037	hsa-miR-499a-3p	CLIP-seq
MIRT1451038	hsa-miR-503	CLIP-seq
MIRT1451067	hsa-miR-510	CLIP-seq
MIRT1451068	hsa-miR-512-5p	CLIP-seq
MIRT1451040	hsa-miR-513b	CLIP-seq
MIRT1451041	hsa-miR-520d-5p	CLIP-seq
MIRT1451042	hsa-miR-524-5p	CLIP-seq
MIRT2134832	hsa-miR-548an	CLIP-seq
MIRT2356091	hsa-miR-548c-3p	CLIP-seq
MIRT2356092	hsa-miR-548o	CLIP-seq
MIRT2356093	hsa-miR-548s	CLIP-seq
MIRT2649605	hsa-miR-549	CLIP-seq
MIRT2356094	hsa-miR-566	CLIP-seq
MIRT2356095	hsa-miR-588	CLIP-seq
MIRT2134836	hsa-miR-605	CLIP-seq
MIRT2649606	hsa-miR-617	CLIP-seq
MIRT2462275	hsa-miR-619	CLIP-seq
MIRT2649607	hsa-miR-627	CLIP-seq
MIRT2134837	hsa-miR-636	CLIP-seq
MIRT1451044	hsa-miR-646	CLIP-seq
MIRT2134839	hsa-miR-924	CLIP-seq
MIRT1451071	hsa-miR-940	CLIP-seq
MIRT2356081	hsa-miR-1323	CLIP-seq
MIRT2356092	hsa-miR-548o	CLIP-seq
MIRT2356081	hsa-miR-1323	CLIP-seq
MIRT1451047	hsa-miR-1827	CLIP-seq
MIRT2134813	hsa-miR-216a	CLIP-seq
MIRT2134814	hsa-miR-216b	CLIP-seq
MIRT2356082	hsa-miR-3065-3p	CLIP-seq
MIRT1451076	hsa-miR-3122	CLIP-seq
MIRT2356083	hsa-miR-3187-3p	CLIP-seq
MIRT1451049	hsa-miR-34b	CLIP-seq
MIRT1451051	hsa-miR-3664-3p	CLIP-seq
MIRT1451081	hsa-miR-3689a-3p	CLIP-seq
MIRT1451082	hsa-miR-3689c	CLIP-seq
MIRT1451083	hsa-miR-3913-5p	CLIP-seq
MIRT2356085	hsa-miR-3926	CLIP-seq
MIRT1451055	hsa-miR-3929	CLIP-seq
MIRT1451056	hsa-miR-4419b	CLIP-seq
MIRT1451057	hsa-miR-4433	CLIP-seq
MIRT2356086	hsa-miR-4435	CLIP-seq
MIRT2649602	hsa-miR-4453	CLIP-seq
MIRT2356088	hsa-miR-4470	CLIP-seq
MIRT1451059	hsa-miR-4478	CLIP-seq
MIRT2649603	hsa-miR-4538	CLIP-seq
MIRT1451060	hsa-miR-4649-3p	CLIP-seq
MIRT2356089	hsa-miR-4684-5p	CLIP-seq
MIRT1451061	hsa-miR-4695-5p	CLIP-seq
MIRT2356090	hsa-miR-4701-5p	CLIP-seq
MIRT1451062	hsa-miR-4722-5p	CLIP-seq
MIRT1451087	hsa-miR-4728-5p	CLIP-seq
MIRT1451064	hsa-miR-485-5p	CLIP-seq
MIRT1451067	hsa-miR-510	CLIP-seq
MIRT1451068	hsa-miR-512-5p	CLIP-seq
MIRT2356091	hsa-miR-548c-3p	CLIP-seq
MIRT2356092	hsa-miR-548o	CLIP-seq
MIRT2356093	hsa-miR-548s	CLIP-seq
MIRT2356094	hsa-miR-566	CLIP-seq
MIRT2356095	hsa-miR-588	CLIP-seq
MIRT2462275	hsa-miR-619	CLIP-seq
MIRT1451071	hsa-miR-940	CLIP-seq

Show/Hide all (41)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005164	Function	Tumor necrosis factor receptor binding	IEA
GO:0005515	Function	Protein binding	IPI	9153189, 9162022, 15121867, 21516116, 21822258, 22493164, 25241761, 25416956, 27107012, 28514442, 32296183, 32814053, 33961781
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	15121867
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IDA	21399614
GO:0005829	Component	Cytosol	IDA	15121867
GO:0005829	Component	Cytosol	IEA
GO:0006915	Process	Apoptotic process	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0007165	Process	Signal transduction	IEA
GO:0007165	Process	Signal transduction	TAS	9511754
GO:0007166	Process	Cell surface receptor signaling pathway	IBA
GO:0007166	Process	Cell surface receptor signaling pathway	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	IEA
GO:0009898	Component	Cytoplasmic side of plasma membrane	IBA
GO:0009898	Component	Cytoplasmic side of plasma membrane	IEA
GO:0009898	Component	Cytoplasmic side of plasma membrane	ISS
GO:0023019	Process	Signal transduction involved in regulation of gene expression	IEA
GO:0023035	Process	CD40 signaling pathway	IDA	15708970
GO:0031625	Function	Ubiquitin protein ligase binding	IEA
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	11279055
GO:0031996	Function	Thioesterase binding	IEA
GO:0031996	Function	Thioesterase binding	IPI	11279055
GO:0033209	Process	Tumor necrosis factor-mediated signaling pathway	IMP	12296995
GO:0035591	Function	Signaling adaptor activity	IBA
GO:0035631	Component	CD40 receptor complex	IEA
GO:0035631	Component	CD40 receptor complex	ISS
GO:0042802	Function	Identical protein binding	IEA
GO:0042802	Function	Identical protein binding	IPI	22493164, 25416956, 32296183
GO:0042981	Process	Regulation of apoptotic process	IEA
GO:0043122	Process	Regulation of canonical NF-kappaB signal transduction	IBA
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IEA
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IEP	12761501
GO:0043123	Process	Positive regulation of canonical NF-kappaB signal transduction	IMP	12296995
GO:0046872	Function	Metal ion binding	IEA
GO:0048255	Process	MRNA stabilization	IEA
GO:0051092	Process	Positive regulation of NF-kappaB transcription factor activity	IMP	15121867
GO:0061630	Function	Ubiquitin protein ligase activity	IDA	26453305
GO:0097400	Process	Interleukin-17-mediated signaling pathway	IEA

MIM	HGNC	e!Ensembl
602356	12035	ENSG00000082512

O00463

Protein name

TNF receptor-associated factor 5 (RING finger protein 84)

Protein function

Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably

PDB

7L3L

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00097	zf-C3HC4	45 → 83	Zinc finger, C3HC4 type (RING finger)	Domain
PF02176	zf-TRAF	128 → 183	TRAF-type zinc finger	Family
PF02176	zf-TRAF	183 → 241	TRAF-type zinc finger	Family

Tissue specificity

TISSUE SPECIFICITY: Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood.

Sequence

MAYSEEHKGMPCGFIRQNSGNSISLDFEPSIEYQFVERLEERYKCAFCHSVLHNPHQTGC
GHRFCQHCILSLRELNTVPICPVDKEVIKSQEVFKDNCCKREVLNLYVYCSNAPGCNAKV
ILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCLYCKKDVVVINL
QNHEENLCPEYPVFCPNNCAKIILKTEVDEHLAVCPEAEQDCPFKHYGCAVTDKRRNLQQ
HEHSALREHMRLVLEKNVQLEEQISDLHKSLEQKESKIQQLAETIKKLEKEFKQFAQLFG
KNGSFLPNIQVFASHIDKSAWLEAQVHQLLQMVNQQQNKFDLRPLMEAVDTVKQKITLLE
NNDQRLAVLEEETNKHDTHINIHKAQLSKNEERFKLLEGTCYNGKLIWKVTDYKMKKREA
VDGHTVSIFSQSFYTSRCGYRLCARAYLNGDGSGRGSHLSLYFVVMRGEFDSLLQWPFRQ
RVTLMLLDQSGKKNIMETFKPDPNSSSFKRPDGEMNIASGCPRFVAHSVLENAKNAYIKD
DTLFLKVAVDLTDLEDL

Sequence length

557

Interactions

View interactions

	KEGG
	NF-kappa B signaling pathway Necroptosis NOD-like receptor signaling pathway IL-17 signaling pathway TNF signaling pathway Shigellosis Human cytomegalovirus infection Herpes simplex virus 1 infection Epstein-Barr virus infection Human immunodeficiency virus 1 infection Pathways in cancer Viral carcinogenesis Small cell lung cancer

Show/Hide Causal Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Multiple myeloma	Likely pathogenic	rs756183569	RCV000984094

Show/Hide Unknown Diseases (1)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Chronic lymphocytic leukemia/small lymphocytic lymphoma	Uncertain significance	rs149548418	RCV005939283

Show/Hide Text Mining Associations (32)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Adenocarcinoma of Lung	Inhibit	38088510
Arthritis Rheumatoid	Associate	17277003
Atherosclerosis	Associate	37330462
Autoimmune Diseases	Associate	24020968, 24416204
Behcet Syndrome	Associate	24416204
Carcinoma Hepatocellular	Associate	30021196, 37366426
Carcinoma Ovarian Epithelial	Associate	34983361
Colitis	Stimulate	23329887
Colitis Ulcerative	Associate	23329887
Colorectal Neoplasms	Associate	29328486
Crohn Disease	Stimulate	23329887
Dermatitis Herpetiformis	Associate	22991566
Glioma	Associate	22593207
Hereditary leiomyomatosis and renal cell cancer	Associate	12000717
HTLV I Infections	Associate	17409010
Inflammation	Associate	26308008, 26453305
Inflammatory Bowel Diseases	Associate	23329887
Leukemia	Associate	10595933
Lipoma of the Conjunctiva	Associate	34349764
Lupus Erythematosus Systemic	Associate	26453305
Lymphoma Large B Cell Diffuse	Associate	19412164, 36619898
Malformations of Cortical Development Group I	Stimulate	15749123
Neoplasm Metastasis	Associate	38088510
Neoplasms	Associate	15142883, 30021196, 38088510
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	31722554
Prostatic Neoplasms	Associate	29202848
Retinal Vasculitis	Associate	24020968
Sjogren's Syndrome	Associate	34349764
Spondylitis Ankylosing	Associate	24020968
Uveitis	Associate	24020968
Uveitis Anterior	Associate	24020968
Uveomeningoencephalitic Syndrome	Associate	24416204

TRAF5 (TNF receptor associated factor 5)