Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	7185
Gene name Gene Name - the full gene name approved by the HGNC.	TNF receptor associated factor 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	TRAF1
Synonyms (NCBI Gene) Gene synonyms aliases	EBI6, MGC:10353
Chromosome Chromosome number	9
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	9q33.2
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form

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miRTarBase ID	miRNA	Experiments	Reference
MIRT027456	hsa-miR-98-5p	Microarray	19088304
MIRT028837	hsa-miR-26b-5p	Microarray	19088304
MIRT043860	hsa-miR-378a-3p	CLASH	23622248
MIRT709882	hsa-miR-361-3p	HITS-CLIP	19536157
MIRT709881	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709880	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709879	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709878	hsa-miR-4763-5p	HITS-CLIP	19536157
MIRT709877	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709876	hsa-miR-6894-3p	HITS-CLIP	19536157
MIRT709875	hsa-miR-6514-3p	HITS-CLIP	19536157
MIRT709874	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT717286	hsa-miR-136-3p	HITS-CLIP	19536157
MIRT717285	hsa-miR-382-3p	HITS-CLIP	19536157
MIRT717284	hsa-miR-6733-3p	HITS-CLIP	19536157
MIRT717283	hsa-miR-4302	HITS-CLIP	19536157
MIRT717282	hsa-miR-5196-3p	HITS-CLIP	19536157
MIRT717281	hsa-miR-4793-5p	HITS-CLIP	19536157
MIRT717280	hsa-miR-370-3p	HITS-CLIP	19536157
MIRT717279	hsa-miR-6893-3p	HITS-CLIP	19536157
MIRT717278	hsa-miR-6870-3p	HITS-CLIP	19536157
MIRT717277	hsa-miR-302a-5p	HITS-CLIP	19536157
MIRT717276	hsa-miR-200c-5p	HITS-CLIP	19536157
MIRT717275	hsa-miR-550a-3p	HITS-CLIP	19536157
MIRT717274	hsa-miR-4711-3p	HITS-CLIP	19536157
MIRT717273	hsa-miR-4276	HITS-CLIP	19536157
MIRT709882	hsa-miR-361-3p	HITS-CLIP	19536157
MIRT709881	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709880	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709879	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709878	hsa-miR-4763-5p	HITS-CLIP	19536157
MIRT717272	hsa-miR-1251-3p	HITS-CLIP	19536157
MIRT709877	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709876	hsa-miR-6894-3p	HITS-CLIP	19536157
MIRT709875	hsa-miR-6514-3p	HITS-CLIP	19536157
MIRT717271	hsa-miR-4774-3p	HITS-CLIP	19536157
MIRT709874	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT709882	hsa-miR-361-3p	HITS-CLIP	19536157
MIRT709881	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709880	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709879	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709878	hsa-miR-4763-5p	HITS-CLIP	19536157
MIRT709877	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709876	hsa-miR-6894-3p	HITS-CLIP	19536157
MIRT709875	hsa-miR-6514-3p	HITS-CLIP	19536157
MIRT709874	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT709882	hsa-miR-361-3p	HITS-CLIP	19536157
MIRT709881	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709880	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709879	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709878	hsa-miR-4763-5p	HITS-CLIP	19536157
MIRT709877	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709876	hsa-miR-6894-3p	HITS-CLIP	19536157
MIRT709875	hsa-miR-6514-3p	HITS-CLIP	19536157
MIRT709874	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT665672	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT665671	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT665670	hsa-miR-940	HITS-CLIP	23824327
MIRT665669	hsa-miR-3929	HITS-CLIP	23824327
MIRT665668	hsa-miR-4419b	HITS-CLIP	23824327
MIRT665667	hsa-miR-4478	HITS-CLIP	23824327
MIRT665666	hsa-miR-5690	HITS-CLIP	23824327
MIRT665665	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT665664	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT665663	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT665662	hsa-miR-769-5p	HITS-CLIP	23824327
MIRT665661	hsa-miR-1827	HITS-CLIP	23824327
MIRT665660	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT665659	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT665658	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT455550	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT665657	hsa-miR-6807-5p	HITS-CLIP	23824327
MIRT665656	hsa-miR-665	HITS-CLIP	23824327
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	20371350
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	20371350
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	20371350
MIRT455554	hsa-miR-558	PAR-CLIP	20371350
MIRT455553	hsa-miR-4487	PAR-CLIP	20371350
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	20371350
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	20371350
MIRT550671	hsa-miR-483-5p	PAR-CLIP	21572407
MIRT550670	hsa-miR-3976	PAR-CLIP	21572407
MIRT550668	hsa-miR-4781-3p	PAR-CLIP	21572407
MIRT550669	hsa-miR-31-3p	PAR-CLIP	21572407
MIRT550667	hsa-miR-6131	PAR-CLIP	21572407
MIRT550665	hsa-miR-6501-5p	PAR-CLIP	21572407
MIRT550666	hsa-miR-4423-5p	PAR-CLIP	21572407
MIRT550664	hsa-miR-744-3p	PAR-CLIP	21572407
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	22012620
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	22012620
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	22012620
MIRT455554	hsa-miR-558	PAR-CLIP	22012620
MIRT455553	hsa-miR-4487	PAR-CLIP	22012620
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	22012620
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	22012620
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	22012620
MIRT528309	hsa-miR-455-3p	PAR-CLIP	22012620
MIRT528308	hsa-miR-6516-5p	PAR-CLIP	22012620
MIRT528307	hsa-miR-1273g-3p	PAR-CLIP	22012620
MIRT455571	hsa-miR-320e	PAR-CLIP	23592263
MIRT455570	hsa-miR-922	PAR-CLIP	23592263
MIRT455569	hsa-miR-214-3p	PAR-CLIP	23592263
MIRT455568	hsa-miR-3619-5p	PAR-CLIP	23592263
MIRT455567	hsa-miR-761	PAR-CLIP	23592263
MIRT455566	hsa-miR-3665	PAR-CLIP	23592263
MIRT455565	hsa-miR-6077	PAR-CLIP	23592263
MIRT455564	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT455563	hsa-miR-7154-3p	PAR-CLIP	23592263
MIRT455562	hsa-miR-765	PAR-CLIP	23592263
MIRT455561	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT455560	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT455558	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT455559	hsa-miR-4291	PAR-CLIP	23592263
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	23592263
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	23592263
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	23592263
MIRT455554	hsa-miR-558	PAR-CLIP	23592263
MIRT455553	hsa-miR-4487	PAR-CLIP	23592263
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	23592263
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	23592263
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	26701625
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	26701625
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	26701625
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	26701625
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	26701625
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	26701625
MIRT455553	hsa-miR-4487	PAR-CLIP	26701625
MIRT455553	hsa-miR-4487	PAR-CLIP	26701625
MIRT455553	hsa-miR-4487	PAR-CLIP	26701625
MIRT455553	hsa-miR-4487	PAR-CLIP	26701625
MIRT455553	hsa-miR-4487	PAR-CLIP	26701625
MIRT455553	hsa-miR-4487	PAR-CLIP	26701625
MIRT528309	hsa-miR-455-3p	PAR-CLIP	26701625
MIRT528309	hsa-miR-455-3p	PAR-CLIP	26701625
MIRT455554	hsa-miR-558	PAR-CLIP	26701625
MIRT455554	hsa-miR-558	PAR-CLIP	26701625
MIRT455554	hsa-miR-558	PAR-CLIP	26701625
MIRT455554	hsa-miR-558	PAR-CLIP	26701625
MIRT455554	hsa-miR-558	PAR-CLIP	26701625
MIRT455554	hsa-miR-558	PAR-CLIP	26701625
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	26701625
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	26701625
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	26701625
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	26701625
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	26701625
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	26701625
MIRT528308	hsa-miR-6516-5p	PAR-CLIP	26701625
MIRT528308	hsa-miR-6516-5p	PAR-CLIP	26701625
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	26701625
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	26701625
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	26701625
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	26701625
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	26701625
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	26701625
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	26701625
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	26701625
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	26701625
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	26701625
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	26701625
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	26701625
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	26701625
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	26701625
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	26701625
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	26701625
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	26701625
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	26701625
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	26701625
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	26701625
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	26701625
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	26701625
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	26701625
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	26701625
MIRT528307	hsa-miR-1273g-3p	PAR-CLIP	27292025
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	27292025
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	27292025
MIRT455553	hsa-miR-4487	PAR-CLIP	27292025
MIRT455553	hsa-miR-4487	PAR-CLIP	27292025
MIRT455554	hsa-miR-558	PAR-CLIP	27292025
MIRT455554	hsa-miR-558	PAR-CLIP	27292025
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	27292025
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	27292025
MIRT528308	hsa-miR-6516-5p	PAR-CLIP	27292025
MIRT528308	hsa-miR-6516-5p	PAR-CLIP	27292025
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	27292025
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	27292025
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	27292025
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	27292025
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	27292025
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	27292025
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	27292025
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	27292025
MIRT734554	hsa-miR-532-3p	Luciferase reporter assay, Western blotting	32368615
MIRT709882	hsa-miR-361-3p	HITS-CLIP	19536157
MIRT709881	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709880	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709879	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709878	hsa-miR-4763-5p	HITS-CLIP	19536157
MIRT709877	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709876	hsa-miR-6894-3p	HITS-CLIP	19536157
MIRT709875	hsa-miR-6514-3p	HITS-CLIP	19536157
MIRT709874	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT717286	hsa-miR-136-3p	HITS-CLIP	19536157
MIRT717285	hsa-miR-382-3p	HITS-CLIP	19536157
MIRT717284	hsa-miR-6733-3p	HITS-CLIP	19536157
MIRT717283	hsa-miR-4302	HITS-CLIP	19536157
MIRT717282	hsa-miR-5196-3p	HITS-CLIP	19536157
MIRT717281	hsa-miR-4793-5p	HITS-CLIP	19536157
MIRT717280	hsa-miR-370-3p	HITS-CLIP	19536157
MIRT717279	hsa-miR-6893-3p	HITS-CLIP	19536157
MIRT717278	hsa-miR-6870-3p	HITS-CLIP	19536157
MIRT717277	hsa-miR-302a-5p	HITS-CLIP	19536157
MIRT717276	hsa-miR-200c-5p	HITS-CLIP	19536157
MIRT717275	hsa-miR-550a-3p	HITS-CLIP	19536157
MIRT717274	hsa-miR-4711-3p	HITS-CLIP	19536157
MIRT717273	hsa-miR-4276	HITS-CLIP	19536157
MIRT709882	hsa-miR-361-3p	HITS-CLIP	19536157
MIRT709881	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709880	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709879	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709878	hsa-miR-4763-5p	HITS-CLIP	19536157
MIRT717272	hsa-miR-1251-3p	HITS-CLIP	19536157
MIRT709877	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709876	hsa-miR-6894-3p	HITS-CLIP	19536157
MIRT709875	hsa-miR-6514-3p	HITS-CLIP	19536157
MIRT717271	hsa-miR-4774-3p	HITS-CLIP	19536157
MIRT709874	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT709882	hsa-miR-361-3p	HITS-CLIP	19536157
MIRT709881	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709880	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709879	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709878	hsa-miR-4763-5p	HITS-CLIP	19536157
MIRT709877	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709876	hsa-miR-6894-3p	HITS-CLIP	19536157
MIRT709875	hsa-miR-6514-3p	HITS-CLIP	19536157
MIRT709874	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT709882	hsa-miR-361-3p	HITS-CLIP	19536157
MIRT709881	hsa-miR-6778-3p	HITS-CLIP	19536157
MIRT709880	hsa-miR-6791-3p	HITS-CLIP	19536157
MIRT709879	hsa-miR-6829-3p	HITS-CLIP	19536157
MIRT709878	hsa-miR-4763-5p	HITS-CLIP	19536157
MIRT709877	hsa-miR-6836-3p	HITS-CLIP	19536157
MIRT709876	hsa-miR-6894-3p	HITS-CLIP	19536157
MIRT709875	hsa-miR-6514-3p	HITS-CLIP	19536157
MIRT709874	hsa-miR-3152-5p	HITS-CLIP	19536157
MIRT665672	hsa-miR-6808-5p	HITS-CLIP	23824327
MIRT665671	hsa-miR-6893-5p	HITS-CLIP	23824327
MIRT665670	hsa-miR-940	HITS-CLIP	23824327
MIRT665669	hsa-miR-3929	HITS-CLIP	23824327
MIRT665668	hsa-miR-4419b	HITS-CLIP	23824327
MIRT665667	hsa-miR-4478	HITS-CLIP	23824327
MIRT665666	hsa-miR-5690	HITS-CLIP	23824327
MIRT665665	hsa-miR-4768-3p	HITS-CLIP	23824327
MIRT665664	hsa-miR-6746-5p	HITS-CLIP	23824327
MIRT665663	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT665662	hsa-miR-769-5p	HITS-CLIP	23824327
MIRT665661	hsa-miR-1827	HITS-CLIP	23824327
MIRT665660	hsa-miR-485-5p	HITS-CLIP	23824327
MIRT665659	hsa-miR-6884-5p	HITS-CLIP	23824327
MIRT665658	hsa-miR-4722-5p	HITS-CLIP	23824327
MIRT455550	hsa-miR-7160-5p	HITS-CLIP	23824327
MIRT665657	hsa-miR-6807-5p	HITS-CLIP	23824327
MIRT665656	hsa-miR-665	HITS-CLIP	23824327
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	20371350
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	20371350
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	20371350
MIRT455554	hsa-miR-558	PAR-CLIP	20371350
MIRT455553	hsa-miR-4487	PAR-CLIP	20371350
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	20371350
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	20371350
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	20371350
MIRT550671	hsa-miR-483-5p	PAR-CLIP	21572407
MIRT550670	hsa-miR-3976	PAR-CLIP	21572407
MIRT550668	hsa-miR-4781-3p	PAR-CLIP	21572407
MIRT550669	hsa-miR-31-3p	PAR-CLIP	21572407
MIRT550667	hsa-miR-6131	PAR-CLIP	21572407
MIRT550665	hsa-miR-6501-5p	PAR-CLIP	21572407
MIRT550666	hsa-miR-4423-5p	PAR-CLIP	21572407
MIRT550664	hsa-miR-744-3p	PAR-CLIP	21572407
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	22012620
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	22012620
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	22012620
MIRT455554	hsa-miR-558	PAR-CLIP	22012620
MIRT455553	hsa-miR-4487	PAR-CLIP	22012620
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	22012620
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	22012620
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	22012620
MIRT528309	hsa-miR-455-3p	PAR-CLIP	22012620
MIRT528308	hsa-miR-6516-5p	PAR-CLIP	22012620
MIRT528307	hsa-miR-1273g-3p	PAR-CLIP	22012620
MIRT455571	hsa-miR-320e	PAR-CLIP	23592263
MIRT455570	hsa-miR-922	PAR-CLIP	23592263
MIRT455569	hsa-miR-214-3p	PAR-CLIP	23592263
MIRT455568	hsa-miR-3619-5p	PAR-CLIP	23592263
MIRT455567	hsa-miR-761	PAR-CLIP	23592263
MIRT455566	hsa-miR-3665	PAR-CLIP	23592263
MIRT455565	hsa-miR-6077	PAR-CLIP	23592263
MIRT455564	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT455563	hsa-miR-7154-3p	PAR-CLIP	23592263
MIRT455562	hsa-miR-765	PAR-CLIP	23592263
MIRT455561	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT455560	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT455558	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT455559	hsa-miR-4291	PAR-CLIP	23592263
MIRT455557	hsa-miR-6890-3p	PAR-CLIP	23592263
MIRT455556	hsa-miR-7162-3p	PAR-CLIP	23592263
MIRT455555	hsa-miR-3160-3p	PAR-CLIP	23592263
MIRT455554	hsa-miR-558	PAR-CLIP	23592263
MIRT455553	hsa-miR-4487	PAR-CLIP	23592263
MIRT455552	hsa-miR-6499-3p	PAR-CLIP	23592263
MIRT455551	hsa-miR-7112-3p	PAR-CLIP	23592263
MIRT455550	hsa-miR-7160-5p	PAR-CLIP	23592263
MIRT1450692	hsa-miR-1182	CLIP-seq
MIRT1450693	hsa-miR-15a	CLIP-seq
MIRT1450694	hsa-miR-15b	CLIP-seq
MIRT1450695	hsa-miR-16	CLIP-seq
MIRT1450696	hsa-miR-1909	CLIP-seq
MIRT1450697	hsa-miR-195	CLIP-seq
MIRT1450698	hsa-miR-214	CLIP-seq
MIRT1450699	hsa-miR-3175	CLIP-seq
MIRT1450700	hsa-miR-424	CLIP-seq
MIRT1450701	hsa-miR-497	CLIP-seq
MIRT1450702	hsa-miR-873	CLIP-seq
MIRT1450703	hsa-miR-1207-5p	CLIP-seq
MIRT1450704	hsa-miR-128	CLIP-seq
MIRT1450705	hsa-miR-1304	CLIP-seq
MIRT1450706	hsa-miR-1321	CLIP-seq
MIRT1450707	hsa-miR-1908	CLIP-seq
MIRT1450708	hsa-miR-1910	CLIP-seq
MIRT1450709	hsa-miR-27a	CLIP-seq
MIRT1450710	hsa-miR-27b	CLIP-seq
MIRT1450711	hsa-miR-3141	CLIP-seq
MIRT1450712	hsa-miR-3675-3p	CLIP-seq
MIRT1450713	hsa-miR-3909	CLIP-seq
MIRT1450714	hsa-miR-3919	CLIP-seq
MIRT1450715	hsa-miR-3924	CLIP-seq
MIRT1450716	hsa-miR-4270	CLIP-seq
MIRT1450717	hsa-miR-4436b-3p	CLIP-seq
MIRT1450718	hsa-miR-4441	CLIP-seq
MIRT1450719	hsa-miR-4447	CLIP-seq
MIRT1450720	hsa-miR-4472	CLIP-seq
MIRT1450721	hsa-miR-4651	CLIP-seq
MIRT1450722	hsa-miR-4659a-5p	CLIP-seq
MIRT1450723	hsa-miR-4659b-5p	CLIP-seq
MIRT1450724	hsa-miR-4728-5p	CLIP-seq
MIRT1450725	hsa-miR-4739	CLIP-seq
MIRT1450726	hsa-miR-4756-3p	CLIP-seq
MIRT1450727	hsa-miR-4756-5p	CLIP-seq
MIRT1450728	hsa-miR-4761-3p	CLIP-seq
MIRT1450729	hsa-miR-4763-3p	CLIP-seq
MIRT1450730	hsa-miR-4776-3p	CLIP-seq
MIRT1450731	hsa-miR-4786-3p	CLIP-seq
MIRT1450732	hsa-miR-608	CLIP-seq
MIRT1450733	hsa-miR-663	CLIP-seq
MIRT1450703	hsa-miR-1207-5p	CLIP-seq
MIRT1450734	hsa-miR-1225-3p	CLIP-seq
MIRT1450707	hsa-miR-1908	CLIP-seq
MIRT1450711	hsa-miR-3141	CLIP-seq
MIRT1450735	hsa-miR-3664-3p	CLIP-seq
MIRT1450736	hsa-miR-4433	CLIP-seq
MIRT1450719	hsa-miR-4447	CLIP-seq
MIRT1450737	hsa-miR-4459	CLIP-seq
MIRT1450738	hsa-miR-4469	CLIP-seq
MIRT1450720	hsa-miR-4472	CLIP-seq
MIRT1450739	hsa-miR-4633-3p	CLIP-seq
MIRT1450721	hsa-miR-4651	CLIP-seq
MIRT1450729	hsa-miR-4763-3p	CLIP-seq
MIRT1450732	hsa-miR-608	CLIP-seq
MIRT1450733	hsa-miR-663	CLIP-seq
MIRT1450703	hsa-miR-1207-5p	CLIP-seq
MIRT1450704	hsa-miR-128	CLIP-seq
MIRT2134726	hsa-miR-146b-3p	CLIP-seq
MIRT2134727	hsa-miR-149	CLIP-seq
MIRT1450708	hsa-miR-1910	CLIP-seq
MIRT1450709	hsa-miR-27a	CLIP-seq
MIRT1450710	hsa-miR-27b	CLIP-seq
MIRT2134728	hsa-miR-3064-5p	CLIP-seq
MIRT2134729	hsa-miR-3173-5p	CLIP-seq
MIRT1450713	hsa-miR-3909	CLIP-seq
MIRT1450717	hsa-miR-4436b-3p	CLIP-seq
MIRT2134730	hsa-miR-4722-3p	CLIP-seq
MIRT1450728	hsa-miR-4761-3p	CLIP-seq
MIRT1450729	hsa-miR-4763-3p	CLIP-seq
MIRT2134731	hsa-miR-4794	CLIP-seq
MIRT2134732	hsa-miR-874	CLIP-seq
MIRT2396268	hsa-miR-622	CLIP-seq
MIRT2694016	hsa-miR-3689d	CLIP-seq
MIRT2694017	hsa-miR-383	CLIP-seq
MIRT2694018	hsa-miR-432	CLIP-seq
MIRT2694019	hsa-miR-4443	CLIP-seq
MIRT2694020	hsa-miR-4709-3p	CLIP-seq
MIRT2694021	hsa-miR-4772-5p	CLIP-seq
MIRT2694022	hsa-miR-604	CLIP-seq
MIRT2396268	hsa-miR-622	CLIP-seq
MIRT2694023	hsa-miR-647	CLIP-seq

Transcription factors

Show/Hide all(5)

Transcription factor	Regulation	Reference
NFKB1	Activation	11297551;17018379;19343319;9733827
NFKB1	Unknown	10823821;14991743;17673602
NFKBIA	Repression	9733827
RELA	Activation	11297551;17018379;19343319;9733827
RELA	Unknown	10823821;14991743;17673602

Show/Hide all(21)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005164	Function	Tumor necrosis factor receptor binding	IBA	21873635
GO:0005164	Function	Tumor necrosis factor receptor binding	IPI	11728344
GO:0005515	Function	Protein binding	IPI	8069916, 9208847, 11279055, 11907583, 14743216, 20447407, 21516116, 21911467, 21988832, 23088713, 23524849, 25241761, 25416956, 26871637, 27107012, 28514442, 29892012, 30561431, 31515488, 32296183
GO:0005737	Component	Cytoplasm	TAS	8069916
GO:0005829	Component	Cytosol	TAS
GO:0006915	Process	Apoptotic process	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0009898	Component	Cytoplasmic side of plasma membrane	IBA	21873635
GO:0010803	Process	Regulation of tumor necrosis factor-mediated signaling pathway	TAS
GO:0031625	Function	Ubiquitin protein ligase binding	IBA	21873635
GO:0031625	Function	Ubiquitin protein ligase binding	IPI	11279055
GO:0031996	Function	Thioesterase binding	IPI	11279055
GO:0033209	Process	Tumor necrosis factor-mediated signaling pathway	IBA	21873635
GO:0042802	Function	Identical protein binding	IPI	8069916, 25416956, 27107012
GO:0043122	Process	Regulation of I-kappaB kinase/NF-kappaB signaling	IBA	21873635
GO:0046330	Process	Positive regulation of JNK cascade	IBA	21873635
GO:0051092	Process	Positive regulation of NF-kappaB transcription factor activity	IDA	10692572
GO:0065003	Process	Protein-containing complex assembly	TAS	8069916
GO:0070534	Process	Protein K63-linked ubiquitination	IBA	21873635
GO:0098802	Component	Plasma membrane signaling receptor complex	IBA	21873635
GO:2001236	Process	Regulation of extrinsic apoptotic signaling pathway	IDA	10692572

MIM	HGNC	e!Ensembl
601711	12031	ENSG00000056558

Protein

UniProt ID

Q13077

Protein name

TNF receptor-associated factor 1 (Epstein-Barr virus-induced protein 6)

Protein function

Adapter molecule that regulates the activation of NF-kappa-B and JNK. Plays a role in the regulation of cell survival and apoptosis. The heterotrimer formed by TRAF1 and TRAF2 is part of a E3 ubiquitin-protein ligase complex that promotes ubiqui

PDB

3M0D , 5E1T , 5H10

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF16673	TRAF_BIRC3_bd	182 → 245	TNF receptor-associated factor BIRC3 binding domain	Coiled-coil

Sequence

MASSSGSSPRPAPDENEFPFGCPPTVCQDPKEPRALCCAGCLSENPRNGEDQICPKCRGE
DLQSISPGSRLRTQEKAHPEVAEAGIGCPFAGVGCSFKGSPQSVQEHEVTSQTSHLNLLL
GFMKQWKARLGCGLESGPMALEQNLSDLQLQAAVEVAGDLEVDCYRAPCSESQEELALQH
FMKEKLLAELEGKLRVFENIVAVLNKEVEASHLALATSIHQSQLDRERILSLEQRVVELQ
QTLAQKDQALGKLEQSLRLMEEASFDGTFLWKITNVTRRCHESACGRTVSLFSPAFYTAK
YGYKLCLRLYLNGDGTGKRTHLSLFIVIMRGEYDALLPWPFRNKVTFMLLDQNNREHAID
AFRPDLSSASFQRPQSETNVASGCPLFFPLSKLQSPKHAYVKDDTMFLKCIVETST

Sequence length

416

Interactions

View interactions

	KEGG		Reactome
	NF-kappa B signaling pathway Apoptosis TNF signaling pathway Pathways in cancer Transcriptional misregulation in cancer Viral carcinogenesis Small cell lung cancer		Regulation of TNFR1 signaling TNFR1-induced NFkappaB signaling pathway

Show/Hide Causal Diseases (5)

Disease term	Disease name	dbSNP ID	References
Causal
Autoimmune diseases	Autoimmune Diseases	rs869025224	21383967
Multiple sclerosis	Multiple Sclerosis	rs104895219, rs483353022, rs483353023, rs483353028, rs483353029, rs483353024, rs483353030, rs3207617, rs483353031, rs483353032, rs483353033, rs483353034, rs483353035, rs483353036, rs483353039 View all (4 more)	22190364
Patent ductus arteriosus	Patent ductus arteriosus, Patent Ductus Arteriosus Familial	rs80338911, rs879253870, rs879253871, rs879255278, rs879255279, rs879253872	19336370
Prostate cancer	Malignant neoplasm of prostate	rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582	17013881
Rheumatoid arthritis	Rheumatoid Arthritis	rs587776843	17804836, 18794853, 19503088, 23143596, 20453842

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Asthma	Asthma			GWAS

Show/Hide Text Mining Associations (49)

Disease Name	Relationship Type	References
Associations from Text Mining
Alzheimer Disease	Associate	26330267
Arthritis	Associate	18593758, 20219786
Arthritis Juvenile	Associate	18593758, 19674979, 19714643
Arthritis Rheumatoid	Associate	17804836, 17880261, 18434327, 18593758, 18759306, 19116907, 19445664, 19503088, 19714643, 19741008, 20219786, 20353580, 21492465, 23125866, 23242182 View all (8 more)
Autoimmune Diseases	Associate	21804190, 29339359, 32231389, 37108746
Breast Neoplasms	Associate	24699530, 29339359
Burkitt Lymphoma	Associate	9733827
Carcinogenesis	Associate	35194031
Carcinoma Hepatocellular	Associate	30021196
Carcinoma Squamous Cell	Associate	22808251
Cognitive Dysfunction	Associate	23710202
Colitis Ulcerative	Associate	31918598
Colorectal Neoplasms	Associate	30173777, 34975867
Death	Associate	19116907
Gastritis Atrophic	Associate	40138873
Glioblastoma	Associate	28926524
Graves Disease	Associate	26699338
Hereditary Angioedema Type III	Associate	29339359
HIV Infections	Associate	29222166
Hodgkin Disease	Associate	12782762
Hodgkin Disease	Stimulate	9885224
IgA Vasculitis	Associate	40717085
Infections	Associate	40138873
Inflammation	Associate	17804836, 23283995, 36049539, 37821650
Inflammation	Stimulate	31918598
Joint Diseases	Associate	25566937
Leukemia	Associate	10595933
Leukemia Lymphocytic Chronic B Cell	Associate	12411322
Liver Cirrhosis Biliary	Associate	23125866, 23710202
Liver Diseases	Associate	23125866
Lupus Erythematosus Systemic	Associate	21905002
Lymphocytic Choriomeningitis	Associate	29222166
Lymphoma	Associate	12502848
Lymphoma B Cell	Stimulate	12933571
Lymphoma Large B Cell Diffuse	Associate	9885224
Lymphoma Large Cell Anaplastic	Associate	25501114, 26187744
Lymphoma Non Hodgkin	Associate	17827388
Lymphoproliferative Disorders	Associate	14521460, 25996949
Multiple Myeloma	Associate	34759347
Multiple Sclerosis	Associate	35561450
Neoplasms	Associate	19116907, 20205706, 26187744, 29339359, 30021196
Osteoporosis	Associate	34910834
Sepsis	Associate	19116907, 20205706
Squamous Cell Carcinoma of Head and Neck	Associate	28381191, 37210507
Stomach Neoplasms	Associate	35936362
Thyroiditis Autoimmune	Associate	26699338
Tooth Erosion	Associate	20219786
Triple Negative Breast Neoplasms	Associate	32235890
Urinary Bladder Neoplasms	Associate	33452764, 35194031

TRAF1 (TNF receptor associated factor 1)