TPD52L1 (TPD52 like 1)

Gene

• Entrez ID: 7164
• Gene name: TPD52 like 1
• Gene symbol: TPD52L1
• Synonyms (NCBI Gene): D53, TPD53
• Chromosome: 6
• Chromosome location: 6q22.31
• Summary: This gene encodes a member of a family of proteins that contain coiled-coil domains and may form hetero- or homomers. The encoded protein is involved in cell proliferation and calcium signaling. It also interacts with the mitogen-activated protein kinase

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT018898	hsa-miR-335-5p	Microarray	18185580
MIRT499298	hsa-miR-200b-3p	PAR-CLIP	24398324
MIRT499297	hsa-miR-200c-3p	PAR-CLIP	24398324
MIRT499296	hsa-miR-429	PAR-CLIP	24398324
MIRT238793	hsa-miR-8066	PAR-CLIP	24398324
MIRT499294	hsa-miR-4724-5p	PAR-CLIP	24398324
MIRT499295	hsa-miR-6513-3p	PAR-CLIP	24398324
MIRT238790	hsa-miR-203a-3p	PAR-CLIP	24398324
MIRT499293	hsa-miR-8069	PAR-CLIP	24398324
MIRT443346	hsa-miR-3173-3p	PAR-CLIP	22100165
MIRT443344	hsa-miR-6891-5p	PAR-CLIP	22100165
MIRT443345	hsa-miR-548p	PAR-CLIP	22100165
MIRT443342	hsa-miR-4695-5p	PAR-CLIP	22100165
MIRT443343	hsa-miR-5589-3p	PAR-CLIP	22100165
MIRT499298	hsa-miR-200b-3p	PAR-CLIP	24398324
MIRT499297	hsa-miR-200c-3p	PAR-CLIP	24398324
MIRT499296	hsa-miR-429	PAR-CLIP	24398324
MIRT238793	hsa-miR-8066	PAR-CLIP	24398324
MIRT499294	hsa-miR-4724-5p	PAR-CLIP	24398324
MIRT499295	hsa-miR-6513-3p	PAR-CLIP	24398324
MIRT238790	hsa-miR-203a-3p	PAR-CLIP	24398324
MIRT499293	hsa-miR-8069	PAR-CLIP	24398324
MIRT443346	hsa-miR-3173-3p	PAR-CLIP	22100165
MIRT443344	hsa-miR-6891-5p	PAR-CLIP	22100165
MIRT443345	hsa-miR-548p	PAR-CLIP	22100165
MIRT443342	hsa-miR-4695-5p	PAR-CLIP	22100165
MIRT443343	hsa-miR-5589-3p	PAR-CLIP	22100165
MIRT1449115	hsa-miR-1261	CLIP-seq
MIRT1449116	hsa-miR-1273f	CLIP-seq
MIRT1449117	hsa-miR-1287	CLIP-seq
MIRT1449118	hsa-miR-1290	CLIP-seq
MIRT1449119	hsa-miR-1324	CLIP-seq
MIRT1449120	hsa-miR-133a	CLIP-seq
MIRT1449121	hsa-miR-133b	CLIP-seq
MIRT1449122	hsa-miR-137	CLIP-seq
MIRT1449123	hsa-miR-1587	CLIP-seq
MIRT1449124	hsa-miR-200b	CLIP-seq
MIRT1449125	hsa-miR-200c	CLIP-seq
MIRT1449126	hsa-miR-203	CLIP-seq
MIRT1449127	hsa-miR-302f	CLIP-seq
MIRT1449128	hsa-miR-3126-3p	CLIP-seq
MIRT1449129	hsa-miR-3132	CLIP-seq
MIRT1449130	hsa-miR-3135b	CLIP-seq
MIRT1449131	hsa-miR-3143	CLIP-seq
MIRT1449132	hsa-miR-3545-5p	CLIP-seq
MIRT1449133	hsa-miR-3941	CLIP-seq
MIRT1449134	hsa-miR-4492	CLIP-seq
MIRT1449135	hsa-miR-4498	CLIP-seq
MIRT1449136	hsa-miR-4501	CLIP-seq
MIRT1449137	hsa-miR-4504	CLIP-seq
MIRT1449138	hsa-miR-4505	CLIP-seq
MIRT1449139	hsa-miR-4514	CLIP-seq
MIRT1449140	hsa-miR-4645-3p	CLIP-seq
MIRT1449141	hsa-miR-4656	CLIP-seq
MIRT1449142	hsa-miR-466	CLIP-seq
MIRT1449143	hsa-miR-4668-3p	CLIP-seq
MIRT1449144	hsa-miR-4672	CLIP-seq
MIRT1449145	hsa-miR-4675	CLIP-seq
MIRT1449146	hsa-miR-4692	CLIP-seq
MIRT1449147	hsa-miR-4741	CLIP-seq
MIRT1449148	hsa-miR-4756-3p	CLIP-seq
MIRT1449149	hsa-miR-4778-3p	CLIP-seq
MIRT1449150	hsa-miR-4782-5p	CLIP-seq
MIRT1449151	hsa-miR-4793-5p	CLIP-seq
MIRT1449152	hsa-miR-4803	CLIP-seq
MIRT1449153	hsa-miR-542-3p	CLIP-seq
MIRT1449154	hsa-miR-628-5p	CLIP-seq
MIRT1449155	hsa-miR-762	CLIP-seq
MIRT1449156	hsa-miR-1206	CLIP-seq
MIRT1449115	hsa-miR-1261	CLIP-seq
MIRT1449116	hsa-miR-1273f	CLIP-seq
MIRT1449118	hsa-miR-1290	CLIP-seq
MIRT1449157	hsa-miR-1292	CLIP-seq
MIRT1449158	hsa-miR-1298	CLIP-seq
MIRT1449119	hsa-miR-1324	CLIP-seq
MIRT1449120	hsa-miR-133a	CLIP-seq
MIRT1449121	hsa-miR-133b	CLIP-seq
MIRT1449123	hsa-miR-1587	CLIP-seq
MIRT1449124	hsa-miR-200b	CLIP-seq
MIRT1449125	hsa-miR-200c	CLIP-seq
MIRT1449126	hsa-miR-203	CLIP-seq
MIRT1449159	hsa-miR-221	CLIP-seq
MIRT1449160	hsa-miR-222	CLIP-seq
MIRT1449128	hsa-miR-3126-3p	CLIP-seq
MIRT1449129	hsa-miR-3132	CLIP-seq
MIRT1449161	hsa-miR-3148	CLIP-seq
MIRT1449162	hsa-miR-3157-5p	CLIP-seq
MIRT1449163	hsa-miR-3177-5p	CLIP-seq
MIRT1449164	hsa-miR-3199	CLIP-seq
MIRT1449165	hsa-miR-330-3p	CLIP-seq
MIRT1449132	hsa-miR-3545-5p	CLIP-seq
MIRT1449166	hsa-miR-3614-3p	CLIP-seq
MIRT1449167	hsa-miR-3662	CLIP-seq
MIRT1449168	hsa-miR-3677-5p	CLIP-seq
MIRT1449169	hsa-miR-3922-5p	CLIP-seq
MIRT1449133	hsa-miR-3941	CLIP-seq
MIRT1449170	hsa-miR-3978	CLIP-seq
MIRT1449171	hsa-miR-4446-5p	CLIP-seq
MIRT1449172	hsa-miR-4471	CLIP-seq
MIRT1449173	hsa-miR-4475	CLIP-seq
MIRT1449134	hsa-miR-4492	CLIP-seq
MIRT1449135	hsa-miR-4498	CLIP-seq
MIRT1449137	hsa-miR-4504	CLIP-seq
MIRT1449138	hsa-miR-4505	CLIP-seq
MIRT1449139	hsa-miR-4514	CLIP-seq
MIRT1449140	hsa-miR-4645-3p	CLIP-seq
MIRT1449141	hsa-miR-4656	CLIP-seq
MIRT1449142	hsa-miR-466	CLIP-seq
MIRT1449174	hsa-miR-4666-5p	CLIP-seq
MIRT1449144	hsa-miR-4672	CLIP-seq
MIRT1449145	hsa-miR-4675	CLIP-seq
MIRT1449146	hsa-miR-4692	CLIP-seq
MIRT1449147	hsa-miR-4741	CLIP-seq
MIRT1449148	hsa-miR-4756-3p	CLIP-seq
MIRT1449149	hsa-miR-4778-3p	CLIP-seq
MIRT1449150	hsa-miR-4782-5p	CLIP-seq
MIRT1449175	hsa-miR-488	CLIP-seq
MIRT1449153	hsa-miR-542-3p	CLIP-seq
MIRT1449176	hsa-miR-548c-3p	CLIP-seq
MIRT1449177	hsa-miR-629	CLIP-seq
MIRT1449178	hsa-miR-661	CLIP-seq
MIRT1449155	hsa-miR-762	CLIP-seq
MIRT1449179	hsa-miR-767-3p	CLIP-seq
MIRT1449156	hsa-miR-1206	CLIP-seq
MIRT1449116	hsa-miR-1273f	CLIP-seq
MIRT1449117	hsa-miR-1287	CLIP-seq
MIRT1449158	hsa-miR-1298	CLIP-seq
MIRT2134369	hsa-miR-1299	CLIP-seq
MIRT2134370	hsa-miR-1301	CLIP-seq
MIRT1449122	hsa-miR-137	CLIP-seq
MIRT1449123	hsa-miR-1587	CLIP-seq
MIRT1449129	hsa-miR-3132	CLIP-seq
MIRT1449130	hsa-miR-3135b	CLIP-seq
MIRT1449162	hsa-miR-3157-5p	CLIP-seq
MIRT2134371	hsa-miR-3184	CLIP-seq
MIRT1449164	hsa-miR-3199	CLIP-seq
MIRT2134372	hsa-miR-3545-3p	CLIP-seq
MIRT1449132	hsa-miR-3545-5p	CLIP-seq
MIRT1449166	hsa-miR-3614-3p	CLIP-seq
MIRT1449168	hsa-miR-3677-5p	CLIP-seq
MIRT2134373	hsa-miR-423-5p	CLIP-seq
MIRT1449173	hsa-miR-4475	CLIP-seq
MIRT1449134	hsa-miR-4492	CLIP-seq
MIRT1449135	hsa-miR-4498	CLIP-seq
MIRT1449138	hsa-miR-4505	CLIP-seq
MIRT2134374	hsa-miR-4539	CLIP-seq
MIRT1449141	hsa-miR-4656	CLIP-seq
MIRT2134375	hsa-miR-4660	CLIP-seq
MIRT1449145	hsa-miR-4675	CLIP-seq
MIRT2134376	hsa-miR-4686	CLIP-seq
MIRT2134377	hsa-miR-4709-3p	CLIP-seq
MIRT1449147	hsa-miR-4741	CLIP-seq
MIRT2134378	hsa-miR-4743	CLIP-seq
MIRT1449148	hsa-miR-4756-3p	CLIP-seq
MIRT2134379	hsa-miR-4766-5p	CLIP-seq
MIRT1449150	hsa-miR-4782-5p	CLIP-seq
MIRT1449151	hsa-miR-4793-5p	CLIP-seq
MIRT1449175	hsa-miR-488	CLIP-seq
MIRT2134380	hsa-miR-5047	CLIP-seq
MIRT2134381	hsa-miR-516b	CLIP-seq
MIRT1449155	hsa-miR-762	CLIP-seq
MIRT1449156	hsa-miR-1206	CLIP-seq
MIRT2355632	hsa-miR-1244	CLIP-seq
MIRT1449115	hsa-miR-1261	CLIP-seq
MIRT2355633	hsa-miR-1267	CLIP-seq
MIRT1449117	hsa-miR-1287	CLIP-seq
MIRT1449157	hsa-miR-1292	CLIP-seq
MIRT1449158	hsa-miR-1298	CLIP-seq
MIRT2134369	hsa-miR-1299	CLIP-seq
MIRT1449120	hsa-miR-133a	CLIP-seq
MIRT1449121	hsa-miR-133b	CLIP-seq
MIRT1449122	hsa-miR-137	CLIP-seq
MIRT1449124	hsa-miR-200b	CLIP-seq
MIRT1449125	hsa-miR-200c	CLIP-seq
MIRT1449126	hsa-miR-203	CLIP-seq
MIRT1449128	hsa-miR-3126-3p	CLIP-seq
MIRT1449130	hsa-miR-3135b	CLIP-seq
MIRT1449162	hsa-miR-3157-5p	CLIP-seq
MIRT2355634	hsa-miR-3171	CLIP-seq
MIRT1449163	hsa-miR-3177-5p	CLIP-seq
MIRT2134371	hsa-miR-3184	CLIP-seq
MIRT1449164	hsa-miR-3199	CLIP-seq
MIRT1449132	hsa-miR-3545-5p	CLIP-seq
MIRT1449166	hsa-miR-3614-3p	CLIP-seq
MIRT1449167	hsa-miR-3662	CLIP-seq
MIRT1449169	hsa-miR-3922-5p	CLIP-seq
MIRT2134373	hsa-miR-423-5p	CLIP-seq
MIRT2355635	hsa-miR-4259	CLIP-seq
MIRT1449171	hsa-miR-4446-5p	CLIP-seq
MIRT2355636	hsa-miR-4457	CLIP-seq
MIRT1449172	hsa-miR-4471	CLIP-seq
MIRT1449136	hsa-miR-4501	CLIP-seq
MIRT1449137	hsa-miR-4504	CLIP-seq
MIRT1449140	hsa-miR-4645-3p	CLIP-seq
MIRT2355637	hsa-miR-4703-3p	CLIP-seq
MIRT2134377	hsa-miR-4709-3p	CLIP-seq
MIRT2355638	hsa-miR-4715-5p	CLIP-seq
MIRT1449149	hsa-miR-4778-3p	CLIP-seq
MIRT1449150	hsa-miR-4782-5p	CLIP-seq
MIRT1449151	hsa-miR-4793-5p	CLIP-seq
MIRT2355639	hsa-miR-513b	CLIP-seq
MIRT2134381	hsa-miR-516b	CLIP-seq
MIRT1449153	hsa-miR-542-3p	CLIP-seq
MIRT1449177	hsa-miR-629	CLIP-seq
MIRT1449178	hsa-miR-661	CLIP-seq
MIRT1449179	hsa-miR-767-3p	CLIP-seq
MIRT1449157	hsa-miR-1292	CLIP-seq
MIRT1449119	hsa-miR-1324	CLIP-seq
MIRT1449163	hsa-miR-3177-5p	CLIP-seq
MIRT1449167	hsa-miR-3662	CLIP-seq
MIRT1449133	hsa-miR-3941	CLIP-seq
MIRT1449172	hsa-miR-4471	CLIP-seq
MIRT1449142	hsa-miR-466	CLIP-seq
MIRT1449144	hsa-miR-4672	CLIP-seq
MIRT1449179	hsa-miR-767-3p	CLIP-seq
MIRT1449157	hsa-miR-1292	CLIP-seq
MIRT1449119	hsa-miR-1324	CLIP-seq
MIRT1449163	hsa-miR-3177-5p	CLIP-seq
MIRT1449133	hsa-miR-3941	CLIP-seq
MIRT1449172	hsa-miR-4471	CLIP-seq
MIRT1449142	hsa-miR-466	CLIP-seq
MIRT1449144	hsa-miR-4672	CLIP-seq
MIRT1449179	hsa-miR-767-3p	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000086	Process	G2/M transition of mitotic cell cycle	IBA
GO:0000086	Process	G2/M transition of mitotic cell cycle	IDA	16112108
GO:0005515	Function	Protein binding	IPI	9484778, 12963375, 14761963, 16631610, 32296183, 33961781
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	12963375, 16112108
GO:0042802	Function	Identical protein binding	IPI	9484778
GO:0042803	Function	Protein homodimerization activity	IDA	9484778
GO:0043406	Process	Positive regulation of MAP kinase activity	IDA	14761963
GO:0046330	Process	Positive regulation of JNK cascade	IBA
GO:0046330	Process	Positive regulation of JNK cascade	IDA	14761963
GO:0048471	Component	Perinuclear region of cytoplasm	IDA	12963375, 16112108
GO:2001235	Process	Positive regulation of apoptotic signaling pathway	IBA
GO:2001235	Process	Positive regulation of apoptotic signaling pathway	IDA	14761963

Other IDs

• MIM: 604069
• HGNC: 12006
• e!Ensembl: ENSG00000111907

Protein

• UniProt ID: Q16890
• Protein name: Tumor protein D53 (hD53) (Tumor protein D52-like 1)
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF04201	TPD52	9 → 187	Tumour protein D52 family	Family

• Sequence:

  MEAQAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAK
  ERHLVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTA
  ISKKFGDMSYSIRHSISMPAMRNSPTFKSFEERVETTVTSLKTKVGGTNPNGGSFEEVLS
  STAHASAQSLAGGSRRTKEEELQC

• Sequence length: 204

Pathways

Reactome:

Golgi Associated Vesicle Biogenesis