Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
7163
Gene name Gene Name - the full gene name approved by the HGNC.
Tumor protein D52
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TPD52
Synonyms (NCBI Gene) Gene synonyms aliases
D52, N8L, PC-1, PrLZ, hD52
Chromosome Chromosome number
8
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
8q21.13
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT021038 hsa-miR-155-5p Proteomics 18668040
MIRT024215 hsa-miR-218-5p Sequencing 20371350
MIRT025584 hsa-miR-34a-5p Sequencing 20371350
MIRT025584 hsa-miR-34a-5p Proteomics 21566225
MIRT027218 hsa-miR-103a-3p Sequencing 20371350
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005509 Function Calcium ion binding IDA 15576473
GO:0005515 Function Protein binding IPI 9484778, 12963375, 15576473, 16631610, 32296183, 33961781
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IDA 15576473, 16112108
GO:0005783 Component Endoplasmic reticulum IDA 10942595
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
604068 12005 ENSG00000076554
Protein
UniProt ID P55327
Protein name Tumor protein D52 (Protein N8)
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF04201 TPD52 49 210 Tumour protein D52 family Family
Tissue specificity TISSUE SPECIFICITY: Isoform 2 is expressed in colon, breast, prostate, pancreas and kidney tumor cell lines. Isoform 2 is expressed at high levels in kidney, prostate, brain, small intestine and pancreas, at moderate levels in placenta and colon, at low l
Sequence
Sequence length 224
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Golgi Associated Vesicle Biogenesis
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Prostate cancer Prostate cancer N/A N/A GWAS
Rheumatoid arthritis Rheumatoid arthritis N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Astrocytoma Associate 31170943
Brain Neoplasms Stimulate 35577881
Breast Neoplasms Stimulate 18959755
Breast Neoplasms Associate 20139910, 25629696, 27983918, 31755218, 33490232
Carcinogenesis Associate 26575170, 37098483
Carcinoma Hepatocellular Associate 25912578
Carcinoma Hepatocellular Inhibit 26575170
Carcinoma Non Small Cell Lung Associate 37564195
Carcinoma Renal Cell Associate 20846453
Carcinoma Squamous Cell Associate 27633630, 27765924