TNFAIP1 (TNF alpha induced protein 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7126 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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TNF alpha induced protein 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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TNFAIP1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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B12, B61, BTBD34, EDP1, hBACURD2 |
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Chromosome
Chromosome number
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17 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17q11.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q13829 | ||||||||||
| Protein name | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2) (BTB/POZ domain-containing protein TNFAIP1) (Protein B12) (Tumor necrosis factor, alpha-induced protein 1, endothelial) | ||||||||||
| Protein function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradatio | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 316 | ||||||||||
| Interactions | View interactions | ||||||||||