TNFAIP1 (TNF alpha induced protein 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
|
7126 |
Gene name
Gene Name - the full gene name approved by the HGNC.
|
TNF alpha induced protein 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
|
TNFAIP1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
|
B12, B61, BTBD34, EDP1, hBACURD2 |
Chromosome
Chromosome number
|
17 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
|
17q11.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
|
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a |
miRNA
miRNA information provided by mirtarbase database.
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
|
|||||||
|
Protein | |||||||||||
UniProt ID | Q13829 | ||||||||||
Protein name | BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2) (BTB/POZ domain-containing protein TNFAIP1) (Protein B12) (Tumor necrosis factor, alpha-induced protein 1, endothelial) | ||||||||||
Protein function | Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(TNFAIP1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradatio | ||||||||||
Family and domains |
Pfam
|
||||||||||
Sequence |
|
||||||||||
Sequence length | 316 | ||||||||||
Interactions | View interactions |