TLN1 (talin 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7094 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Talin 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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TLN1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ILWEQ, TLN, talin-1 |
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Chromosome
Chromosome number
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9 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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9p13.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, includi |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||||||||||||||||||||||
| UniProt ID | Q9Y490 | ||||||||||||||||||||||||||||||
| Protein name | Talin-1 | ||||||||||||||||||||||||||||||
| Protein function | High molecular weight cytoskeletal protein concentrated at regions of cell-matrix and cell-cell contacts. Involved in connections of major cytoskeletal structures to the plasma membrane. With KANK1 co-organize the assembly of cortical microtubul | ||||||||||||||||||||||||||||||
| PDB | 1SYQ , 2MWN , 4DJ9 , 6R9T | ||||||||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: [Isoform 2]: Expressed at low to non-detectable levels in many tissues but highly expressed in skin and pancreas with other tissues including kidney cortex, endocervix, testis, pituitary, liver, and spleen also showing robust expressio | ||||||||||||||||||||||||||||||
| Sequence |
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| Sequence length | 2541 | ||||||||||||||||||||||||||||||
| Interactions | View interactions | ||||||||||||||||||||||||||||||