NR2F2 (nuclear receptor subfamily 2 group F member 2)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7026 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Nuclear receptor subfamily 2 group F member 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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NR2F2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ARP-1, ARP1, CHTD4, COUPTF2, COUPTFB, COUPTFII, NF-E3, SRXX5, SVP40, TFCOUP2 |
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Chromosome
Chromosome number
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15 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q26.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple t |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | P24468 | |||||||||||||||
| Protein name | COUP transcription factor 2 (COUP-TF2) (Apolipoprotein A-I regulatory protein 1) (ARP-1) (COUP transcription factor II) (COUP-TF II) (Nuclear receptor subfamily 2 group F member 2) | |||||||||||||||
| Protein function | Ligand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. B | |||||||||||||||
| PDB | 3CJW | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Ubiquitous. Expressed in the stromal cells of developing fetal ovaries (PubMed:29478779). {ECO:0000269|PubMed:29478779}. | |||||||||||||||
| Sequence |
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| Sequence length | 414 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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