Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6988
Gene name Gene Name - the full gene name approved by the HGNC.
T cell leukemia translocation altered
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TCTA
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
3p21.31
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT022449 hsa-miR-124-3p Microarray 18668037
MIRT029182 hsa-miR-26b-5p Microarray 19088304
MIRT1416732 hsa-miR-1197 CLIP-seq
MIRT1416733 hsa-miR-1205 CLIP-seq
MIRT1416734 hsa-miR-1245b-3p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003674 Function Molecular_function ND
GO:0005515 Function Protein binding IPI 32296183
GO:0016021 Component Integral component of membrane IEA
GO:0045671 Process Negative regulation of osteoclast differentiation IDA 19560569
GO:0072675 Process Osteoclast fusion IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
600690 11692 ENSG00000145022
Protein
UniProt ID P57738
Protein name T-cell leukemia translocation-altered gene protein (T-cell leukemia translocation-associated gene protein)
Protein function May be required for cellular fusion during osteoclastogenesis.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15128 T_cell_tran_alt 12 103 T-cell leukemia translocation-altered Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. Highest level of expression in kidney. Present in monocytes, osteoclasts, macrophages, synoviocytes and synovial lining cells (at protein level). {ECO:0000269|PubMed:7728759}.
Sequence
Sequence length 103
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Crohn disease Crohn Disease 17804789, 18587394 ClinVar
Associations from Text Mining
Disease Name Relationship Type References
Hematologic Neoplasms Associate 40095473
Leukemia Myeloid Acute Associate 40095473
Neoplasms Associate 29596435
Pancreatic Neoplasms Associate 29596435