TCP11 (t-complex 11)

Gene
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
6954
Gene name Gene Name - the full gene name approved by the HGNC.
T-complex 11
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
TCP11
Synonyms (NCBI Gene) Gene synonyms aliases
D6S230E, FPPR
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6p21.31
miRNA miRNA information provided by mirtarbase database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(7)
miRTarBase ID miRNA Experiments Reference
MIRT023346 hsa-miR-122-5p Microarray 17612493
MIRT1416684 hsa-miR-3921 CLIP-seq
MIRT1416685 hsa-miR-4303 CLIP-seq
MIRT1416686 hsa-miR-4537 CLIP-seq
MIRT1416687 hsa-miR-4653-5p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide all(17)
GO ID Ontology Definition Evidence Reference
GO:0001669 Component Acrosomal vesicle IBA 21873635
GO:0001669 Component Acrosomal vesicle IDA 21597245
GO:0001669 Component Acrosomal vesicle ISS
GO:0007165 Process Signal transduction IBA 21873635
GO:0007275 Process Multicellular organism development TAS 1893875
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
MIM HGNC e!Ensembl
186982 11658 ENSG00000124678
Protein
Gene miRNA Gene ontology Other IDs Protein Associated diseases
UniProt ID Q8WWU5
Protein name T-complex protein 11 homolog
Protein function Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization-promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. {ECO:00
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF05794 Tcp11 58 → 487 T-complex protein 11 Family
Tissue specificity TISSUE SPECIFICITY: Isoform 2 and isoform 3 are expressed in sperm. Isoform 1 is not detected in sperm (at protein level) (PubMed:21597245). Testis-specific (PubMed:11756566). Isoform 1, isoform 2 and isoform 3 are expressed in sperm (PubMed:21597245). {E
Sequence
Sequence length 503
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Gene miRNA Gene ontology Other IDs Protein Associated diseases
Show/Hide Unknown Diseases (4)
Unknown
Disease term Disease name Evidence References Source
Asthma Asthma GWAS
Systemic lupus erythematosus Systemic lupus erythematosus GWAS
Sinusitis Sinusitis GWAS
Insomnia Insomnia GWAS
Show/Hide Text Mining Associations (2)
Associations from Text Mining
Disease Name Relationship Type References
Sarcoma Associate 28088687
Uterine Cervical Neoplasms Associate 37697257